DAFTAR PUSTAKA

Ahmad, H., Suprianto., Marhamah., Rasmidar., 2014, Aktivitas Antikanker dan

Antiproliferasi fraksi etanol sarang semut(Myrmecodya pendans) pada sel
kanker lidah manusia SP-C1, Dentofasial, Vol. 13, No.1, 1-6
Anam, S., Yuliet., Agus, R., Firmanita, D.,Dewi, R., Muhammad, S.Z., 2014, Aktivitas
Sitotoksik Ekstrak Metanol Benalu Batu (Begonia sp.): ethnomedicine Suku
Wana Sulawesi Tengah, Jurnal Ilmu Kefarmasian Indonesia, Vol.12 No.1, 10-16
Buncharoen, W., Kanokporn, S., Supap, S., Chatchote, T., 2016, Uvaria rufa Blume
attenuates benign prostatic hyperplasia via inhibiting 5a-reductase and
enhancing antioxidant status, Journal of Ethnopharmacology, JEP10494,
Thailand
Deepralard, K., Kawanishi, K., Moriyasu, M., Pengsuparp, T., Suttisri, R., 2009,
Flavonoid glycosides from the leaves of Uvaria rufa with advanced glycation
end-products inhibitory activity. The Thai J. Pharm. Sci. 33(2): 84-90
Depkes RI., 1995, Farmakope Indonesia edisi IV, Departemen Kesehatan RI : Jakarta
Depkes RI., 2007, Sediaan Galenik, Departemen Kesehatan RI : Jakarta, 5-12
Harborne, J.B., 1987, Metode Fitokimia, Institut Teknologi Bandung :
Bandung.
Hilaria, M., Elisma, Dapa, M.Y., Teti, M., 2016, Antioxidant Activities of Ethyl Acetate
Extract and Hexane Extract of Lelak (Uvaria rufa Blume) Leaves, Asian Journal
of Applied Sciences Volume 04-Issue 04:930-934

Kemenkes RI., 2016, Pusat data dan Informasi Kementerian Kesehatan RI. Kanker
Payudara, Kemenkes RI, Jakarta.

Meiyanto, E., Susidarti, R.A., Handayani, S., Rahmi, F., 2008, Ekstrak etanolik biji buah
pinang (Areca cathecu Linn) mampu menghambat proliferasi dan memacu
apoptosis sel MCF-7, Majalah Farmasi Indonesia, 19 (1): 12-19.
Mihajlivic, M.L dan Petar, M.M., 2008, Recent Advances In Radiation Therapy Of
Cancer Cells: A Step Towards An Experimental And Systems Biology
Framework, Current Radiopharmaceuticals, , Bentham Science Publishers Ltd,
Vol.1 no.1, 22-29, Yugoslavia.
Paragas, E.M., Dietmar. G., Karsten, K., Scott, G.F., Macabeo, A.P.G., 2014, Anti-
Tubercular Flavonol Derivatives from Uvaria rufa, Research Journal of
Pharmaceutical, Biological and Chemical Sciences RJPBCS 5(6): 856-859
Rosandy, A.R., Din, L.B., Yaacob, W.A., Yusoff, N.I., Sahidin, I., Latip, J., Nataqain, S.,
Noor, N.M., 2013, Isolation and characterization of compounds from the stem
bark of Uvaria rufa (Annonaceae), Malaysian J. Anal. Sci, 17(1): 50-58
Rosidah, Y.M.F., Sadikun, A dan Asmawi, M.Z., 2008, Antioxidant Potential of Gynura
procumbens, Pharmaceutical Biol, 46: 616-625
Thang, T.D., Hoang, V.L., Nguyen, N.T., Nguyen, H.H., Do,N.D and Isiaka, A.O., 2014,
Constituents of Essential Oils from the Leaves and Stem Barks of Uvaria rufa
and Uvaria cordata (Annonaceae) from Vietnam, in Journal of essential oil-
bearing plants JEOP 17 (3):427-434
Wahyuningsih, M.S.H., 2010, Potensi Pengembangan Obat Bahan Alam
Indonesia Untuk Penyakit Kanker: Tantangan dan Harapan, Universitas
Gadjah Mada: Yogyakarta.

Wu, S.L., Ng, D.L., Huang, S., Wang, S., Lin, C., 2009, Extract Induces Apoptosis in
Human Hep G2 Cells through CD95/ CD95L system and the Mitochondrial
Signaling Transduction Pathway, Cancer Letters, 215(2):199-208
(https://www.gbif.org/species/3154300) diakses 02/12/2018 pukul 19.51

(Li dan Gilbert, 2011).

Tip-pyang, S., Payakarintarungkul, K., Sichaem, J., Phuwapraisirisan, P., 2011.

Chemical constituents from the roots of Uvaria rufa. Chem. Nat. Compd. 47, 475-
476.
Tudla, F.A., Aguinaldo, A.M., Krohn, K., Hussain, H., Macabeo, A.P.G., 2007.
Highly oxygenated cyclohexene metabolites from Uvaria rufa. Biochem. Syst. Ecol.
35, 45-47.
Macabeo, A.P.G., Tudla, F.A., Alejandro, G.J.D., Kouam, S.F., Hussain, H., Krohn,
K., 2010. Benzoylated derivatives from Uvaria rufa. Biochem. Syst. Ecol. 38, 857-
860.
Nguyen, T.H., Ho, V.D., Do, T.T., Bui, H.T., Phan, V.K., Sak, K., Raal, A., 2015. A new

lignan glycoside from the aerial parts and cytotoxic investigation of Uvaria rufa. Nat. Prod.

Res. 29, 247-252

Azmir J., Zaidul I.S.M., Rahman M.M., Sharif K.M., Mohamed A., Sahena F., Jahurul

M.H.A., Ghafoor K., Norulaini N.A.N. and Omar A.K.M., 2013, Techniques For Extraction

of Bioactive Compounds From Plant Materials: A review, Journal of Food Engineering,

117 (4), 426–436.

Prayong P., Barusrux S., Weerapreeyakul N., 2008, Cytotoxic Activity Screening of

Some Indigenous Thai Plants, Fitoterapia, 79 (7): 598-601.

Kumar V, Abas A.K, dan Foustro N. 2005. Pathology Basic of Dissease. New
York: Elsevier Inc. halaman 270-336.
Sudiana I.K. 2011. Patobiologi Moleuler Kanker. Jakarta: Salemba Empat.
Halaman 1, 45-52.
Vermeulen, K., Berneman, Z.N., and Van Bockstaele, D.R., 2003, Cell Cycle and
Apoptosis, Cell Prolif. 36(3): 165-175.Lapena dan Giordano, 2009

Satyanarayana, A., and Kaldis, P., 2009, Mammalian Cell-cycle Regulation: Several
Cdks, Numerous Cyclins, and Diverse Compensatory Mechanisms, Oncogene,
28: 2925-2939.

Cooper GM and Hausman RE, 2004, The Cell: A Molecular Approach, Fifth Edition,
ASM Press and Sinauer Associates, Inc.

Dhulipala, V.C., Welshons, W.V., and Reddy, C.S., 2006, Cell Cycle Proteins in Normal
and Chemically Induced Abnormal Secondary Palate Development: a Review,
Human Exp. Toxicol. 25: 675-682.
Baumforth and Crocker, 2003, Molecular and Immunological Aspects of Cell
Proliferation, in Molecular Biology in Cellular Pathology, Wiley
(http://onlinelibrary.wiley.com/doi/10.1002/0470867949.ch6/summary)Mulyadi 1997

Khomsan, A., 2009, Rahasia Sehat dengan Makanan Berkhasiat, Buku Kompas,
Jakarta, pp. 16-17
American Cancer Society, 2014, Colorectal Cancer Facts & Figures,
www.cancer.org/research/cancerfactsstatistics/colorectal-cancer-facts-
figures, diakses tanggal 25 Januari 2015.
Braun MS, Seymour MT. Balancing the efficacy and toxicity of
chemotherapy in colorectal cancer. Ther Adv Med Oncol. 2011;3:43-52.

Indrawati M. 2009. Bahaya Kanker bagi Wanita dan Pria. Cetakan pertama.
Jakarta: Pendidikan untuk Kehidupan.
a
[CCRC] Cancer Chemoprevention Research Centre. 2009 . Protokol Uji
sitotoksik. CCRC Fakultas Farmasi UGM.
http://ccrcfarmasi.ugm.wordpress. com/ protokol. [28 Februari 2016
pukul 08.55 AM]
[IARC] International Agency for Research on Cancer / WHO. 2012.
GLOBOCAN: Estimated cancer incidence, mortality, and prevalence
worldwide in 2012.

Corwin E.J. 2009. Buku Saku Patofisiologi. Edisi III. Subekti N B, penerjemah.
Jakarta Penerbit Buku Kedokteran. Terjemahan dari : LippincottWilliams & Wilkins.
Kintzios SE, Barberaki MG. 2005. Plant That Fight Cancer. United States
of America : CRC Press LLC.
Kintzios dan Barberaki, 2003

Meyerhardt, J.A., and Mayer, R.J., 2005, Systemic Therapy for Colorectal Cancer,
N Engl J Med., 352(5), 476-487.
Lapenna, S., and Giordano, A., 2009, Cell Cycle Kinases as Therapeutic Targets for
Cancer, Nat. Rev. Drug Discov. 8(7): 547-566.

Basmal J, Amini S, Sugiyono M. 2009. Seminar Nasional Pengelolahan Produk

dan Bioteknologi Kelautan dan Perikanan. Jakarta. Hal 208
Doyle A, Griffiths JB. 2000. Cell and Tissue Culture for Medical Research.
New York: John Willey and Sons Ltd.
Prawono. (2011). Terapi Medipic. Cetakan I. Jakarta. Hal. 38-39.

Sudiana, I.K., 2008, Patobiologi Molekuler Kanker, Salemba Medika, Jakarta, pp.
1-3, 46.
Chrestella, J., 2009, Neoplasma, Departemen Patologi Anatomi Fakultas Kedokteran,

Universitas Sumatra Utara, Medan, pp. 3-4Ramli 2000

Korsmeyer, S.J., Wei, M.C., Saito, M., Weiler, S., Oh, K.J., and Schlesinger, P.H.,
2000, Pro-apoptotic Cascade Activates BID, which Oligomerizes BAK or
BAX into Pores That Result in The Release of Cytochrome C, Cell Death
Differ, 7, 1166–1173.
Goldie, S.J., Gaffikin, L., Jeremy D., Amparo G.T., Levin, C.I., and Thomas, C.,
2005, Cost-Effectiveness of Cervical Cancer Screening in Five Developing
Countries, N Engl J Med., 353(21), 58-68.
Jong D. Buku Ajar Ilmu Bedah. In: Riwanto Ignatius, Hamami AH, Pieter
John, Tjambolang Tadjuddin Ahmadsyah Ibrahim. Usus Halus, Appendiks,
Kolon, dan Anorektum. Jakarta: EGC, 2013. 731-98.

Hanahan dan Weinberg, 2011

Hanahan, D., and Weinberg, R.A., 2000, The Hallmarks of Cancer, Cell, 100, 59-
60.
Liu, H.C., Chen, G.G., Vlantis, A.C., Leung, B.C.S., Tong, M.C.E., and van
Hasselt, C.A., 2006, 5-Fluorouracil Mediates Apoptosis and G1/S Arrest
in Laryngeal Squamous Cell Carcinoma via a p53-Independent Pathway,
The Cancer Journal, 12(6), 482-483.
Palozza, P., Serini, S., Maggiano, N., Giuseppe, T., Navarra, P., and Ranelletti,
F.O., 2005, β-Carotene Downregulates the Steady-State and Heregulin-a-
Induced COX-2 Pathways in Colon Cancer Cells, J.Nutr., 135, 129.
Giovannetti, E., Backus, H.H.J., Wouters, D., Ferreira, C.G., van Houten, V.M.M.
and Brakenhoff, R.H., 2007, Changes in the Status of p53 Affect Drug
Sensitivity to Thymidylate Synthase (TS) Inhibitors by Altering TS Levels,
British J. Can., 96(3): 769-775.
 Sigmond, J., Backus, H.H., Wouters, D., Temmink, O.H., Jansen, G. and Peters,
G.J., 2008, Induction of Resistance to the Multitargeted Antifolate
Pemetrexed (ALIMTA) in WiDr Human Colon Cancer Cells is
Associated with Thymidilate Synthase Overexpression, Biochem.
Pharmacol 8(3).
Jansen, W.J.M., Zwart, B., Hulscher, S.T.M., Giaccone, Pinedo, H.M. and Boven,
E., 2009, CPT-11 in Human Colon-Cancer Cell Lines and Xenografts:
Characterization of Cellular Sensitivity Determinants, Int. J. Cancer, 70:
335-340.
Goncalves, E.M., Ventura, C.A., Yano. T., Macedo, M.L.D., dan Ganeri, S.C.2009.
Morphological and growth alterations in Vero Cells Transformed by
Cysplatin. Cell Biol. 30(6): 485-494.
Hartati, M.S., Mubarika, S., Bolhuis R.L.H., Nooter, K., Oostrum, R.G., Boersma,
A.W.M., et al., 2003, Sitotoksisitas Rimpang Temu Mangga (Curcuma
mangga Val. &V. Zijp.) dan Kunir Putih (Curcuma zedoaria I.) Terhadap
Beberapa Sel Kanker Manusia (in Vitro) dengan Metoda SRB, Berkala
llmu Kedokteran, 35(4), 198.
Ernawati, F., 2010, Uji Sitotoksik Isolat Aktif dari Ekstrak Kloroform Rumput
Mutiara (Hedyotis corymbosa (L.) Lamk.) Terhadap Sel Hela dan SiHa,
Skripsi, 17-18, Universitas Surakarta.
Nertika, K., 2008, Uji Sitotoksisitas Ekstrak Etanolik Daun Sirih Merah Terhadap
Kultur Sel Kanker Payudara, Skripsi, 16-17, Universitas Sanata Dharma,
Yogyakarta.
Zheng, Z., Huang, W., Yang, Y., Li, Z., Cai, J., and Su, H., 2000, Detection of
Antitumor and Antimicrobial Activities in Marine Organism Associated
Actinomycetes Isolated from the Taiwan Strait, China, Microbiol Lett,
188, 87–91.
Alfarabi, M., Bintang, M., Suryani, and Safithri, M., 2010, The Comparative
Ability of Antioxidant Activity of Piper crocatumin Inhibiting Fatty Acid
Oxidation and Free Radical Scavenging, Hayati J. Biosci, 17(4), 201-204.
Ren, Qiao, Wang, Zhu, and Zhang, 2003, Flavonoids: Promising Anticancer
Agents, Med Research Rev, 23(4), 519-534.
Robinson, T. 1995. Kandungan Senyawa Organik Tumbuhan Tinggi. Terjemahan
Kosasih Padmawinata. Bandung: Penerbit ITB.
Siadi. K.2012. Ekstrak Bungkil Biji Jarak Pagar (Jatropa curcas) Sebagai
Biopestisida Yang Efektif Dengan Penambahan Larutan NaCl.Jurnal Mipa
35(2): 77-83

National Cancer Institute, (2006

American Cancer Society, 2008

Azmir, dkk., 2013).

Akmal, dkk., 2010

Kemenkes RI, 2010

Goncalves, dkk., 2006

Depemede dan Rosyidi 2009

Kupcsik, dkk., 2011

Dewi, dkk., 2013

Setyowati, dkk.,2014)

(Sastrohamidjojo, 1996).

Abcam, 2007

Pebriana, dkk., 2008

Effendy, 2007

Prayong, dkk., 2008)

Taraphdar, 2001)

Raju & Rao, 2004).

Sismindari, 2002

(Beck, dkk., 2001).

King, 2000

Nunez, dkk., 1998

Saleh, dkk., 1999).

Meiyanto, 2002

Sayin, V.I., Ibrahim, M.X., Larsson, E., Nilsson, J.A., Lindahl, P., Bergo, M.O.,
2014, Antioxidants Accelerate Lung Cancer Progression in Mice,
Sci Transl Med, 6, 1-8.