Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
WRITTEN OUTPUT
Case 1
3G Group 4
3 days PTC, patient complained of eye redness and watery discharge, OU upon
waking up. Later that day, she developed periorbital swelling and slight blurring of
vision. Patient applied a topical medication borrowed from her brother who also had
eye redness and tearing a week ago.
The following day, only slight improvement was noted so she applied breast milk on
both eyes. Upon an elderly neighbor’s advice, she also applied a drop of urine (her
own), OU. No consults were made.
1 day PTC, there was noted eye pain and photophobia, OS, profuse, purulent eye
discharge, OU and progressive blurring of vision, OS>OD. Persistence of the
aforementioned symptoms prompted consult.
Discussion
● Signs and Symptoms
○ Purulent discharge on both eyes
○ Eye redness
○ Periorbital swelling
○ Eye pain and photophobia on left eye
○ Progressive blurring of vision, predominantly on the left eye
● PE and Diagnostic or Laboratory Findings
● BCVA:
○ OD 20/30
○ OS HM with PLPj
● IOP:
○ OD soft
○ OS not fully assessed
● Pupils:
○ OD 3mm
○ OS not fully assessed
● EOMS:
○ full and equal
● Etiology
○ Gonococcal conjunctivitis is conjunctivitis caused by Neisseria
gonorrhoeae (gonorrhea), a sexually transmitted disease that also
may spread to the eye by contact with genital secretions from a
person who has a genital gonorrheal infection.
● Pharmacologic Intervention
○ Single dose of 1 g IM Ceftriaxone
○ Single dose of 1 g Oral Azithromycin
○ Corneal transplant on the left eye since there is a presence of corneal
melting
● Adverse Effects
○ Ceftriaxone
■ Diarrhoea, nausea, vomiting; neutropenia, eosinophilia,
anaemia, rash, pruritus, fever, chills, increased serum
concentrations of AST, ALT, BUN; local reactions (e.g. pain,
induration, ecchymosis, tenderness at inj site). Rarely,
pancreatitis, hypoprothrombinaemia.
■ Potentially Fatal: Anaphylaxis, Clostridium difficile-associated
diarrhoea and colitis, haemolytic anaemia.
○ Azithromycin
■ Significant: Myasthenia gravis.
■ Ear and labyrinth disorders: Deafness.
■ Eye disorders: Pruritus, burning, stinging of the eye or ocular
discomfort, sticky eye sensation, foreign body sensation
(ophthalmic).
■ Gastrointestinal disorders: Diarrhoea, vomiting, abdominal pain,
nausea, flatulence, dyspepsia, dysgeusia.
■ General disorders and admin site conditions: Injection site pain,
fatigue.
■ Investigations: Decreased lymphocyte count and blood
bicarbonate; increased eosinophil count, basophils, monocytes
and neutrophils.
■ Metabolism and nutrition disorders: Anorexia.
■ Musculoskeletal and connective tissue disorders: Arthralgia.
■ Nervous system disorders: Headache, dizziness, paraesthesia.
■ Skin and subcutaneous tissue disorders: Pruritus, rash.
■ Potentially Fatal: Rarely, serious hypersensitivity reactions (e.g.
anaphylaxis, angioedema, Stevens-Johnson syndrome, toxic
epidermal necrolysis, acute generalised exanthematous
pustulosis drug reaction with eosinophilia and systemic
symptoms), fulminant hepatitis leading to liver failure,
prolonged cardiac repolarisation and QT interval, cardiac
arrhythmia, torsades de pointes, Clostridium difficile associated
diarrhea (CDAD).
● Surgical Intervention
In cases of severe Gonococcal conjunctivitis where in the integrity of the cornea has
been ulcerated or in if the bacteria has melted the cornea, surgery can be required.