CEREBROVASCULAR DISEASE

AKI
Predisposing Factors: Precipitating Factors: (Pre-renal)
 73 years old  HPN (170/110 mmHg) Atherosclerosis ASHD
DM
 Male  Atrial Fibrillation Nephropathy
 Obesity  Hyperlipidemia DM Dehydration Obstructive
 Lifestyle  Previous Stroke/TIA uropathy
 Diet
 Smoker (50 pack years)
 Alcohol use (6 bottles, 2x/week) Rapture of BV

ISCHEMIC HEMORRHAGIC STROKE

Obstruction of blood
vessels
Embolic
Thrombotic Subtype:
or Atheroma HPN ↓ Cerebral Perfusion
Lacunar Emobuls /
Wandering clot

Heart Extracranial arteries

Obstruction of blood
vessels Create cavities Occlusion

Ischemic cascade: Disruption of cerebral Right frontoparietal area, corona

Aerobic respiration switch blood flow radiate, thalamus, external capsule
to anaerobic respiration (PERIVENTRICULAR AREA)

Producing lactic acid ↓ Cellular function

Increase pH
↓ Cerebral blood flow
Electrolyte imbalance

Vasoconstriction Membrane depolarization

of cell wall, causing increase COMPLICATIONS:
in Calcium, release of  Pnemonia (resolved)
o Frequent coughing
No perfusion glutamate and free radicals
o Coarse crackles left base
o Bilateral ronchi
o Tachypnea
MANIFESTATION:
Brain death  Constipation
 ICTUS (August 26, 2014)
o Abdominal pain
 (+) weakness of upper and lower
o No BM for 4 days
extremities dominant on left
o Bloatedness
STROKE  Dizziness
 Complicted UTI
 Muffled speech o Dysuria
 Difficulty swallowing o Hypogastric pain
 Dysarthria o Distended bladder
 Left hemiplegia