SHIFA

FERTILITY CENTER

Your Dreams
are our
Expertise!

CENTERS, USA LLC

Shifa Fertility Centre

Sector H-8/4, Islamabad - Pakistan
Ph. +92 310 5847521, +92 51 846 4646
or Email: afc@shifa.com.pk
Rizwan Malik
M.D., MSc, FACOG, FACS (USA)
Board Certied

Dr. Malik completed Bachelor of Science in

Biomedical and Electrical Engineering with honors
from University of Southern California School of
Engineering, Los Angeles, USA. He earned his
doctorate of Medicine - MD degree from Boston
University School of Medicine, Boston MA / USA.
Dr Malik completed his residency in Obstetrics &
Gynecology from University of Miami School of
Medicine, sub-specialty Fellowship Training in
Reproductive Endocrinology and Infertility from University of South Alabama,
and Master in Embryology and Andrology from Eastern Virginia Medical
School, Jones Institute for Reproductive Medicine.
Dr Malik is a faculty member at Indiana University School of Medicine,
Fellow of American College of Obstetrics and Gynecology as well as
American College of Surgeons. He is an active member of American College
of Obstetrics and Gynecology as well as American Society of Reproductive
Medicine.
Dr. Malik holds a Board certication from American Board of Obstetrics and
Gynecology.

Botros RMB Rizk

M.D., MA, FRCOG, FRCS, HCLD, FACOG, FACS

Professor and Head, Division of Reproductive

Medicine & Infertility, University of South Alabama,
Mobile AL, is trained in Infertility with Sr Roberts
Edwards, at Bourn Hall, UK. He is author of over
100 peer reviewed articles, editor of over sixteen
textbooks in Infertility Reproductive Endocrinology
and Ultrasound.

Clinic: Center for IVF & Reproductive Medicine,

Shifa International Hospital, H-8/4, Islamabad.
Phone: +92 310 5847521, +92 51 846 4646
E-mail: afc@shifa.com.pk
 INTRODUCTION
Advanced Fertility Centers, USA
and Shifa International Hospital
Pakistan enter into a Joint Venture
to provide Infertility treatment IVF
and ICSI services along with
world class advanced minimally
invasive services to the residents
of Pakistan, Middle East and Sub-
continent
Our team of experts is leading
the world in innovative and surgical procedures performed in the eld of
Gynecology and Reproductive Medicine. Physicians at Shifa Fertility center
are here to help by offering the latest reproductive technologies and
procedures to enhance the possibility of conception. They understand the
physical, emotional and nancial toll that infertility can have on a woman or
man.
Working together, we specialize in determining the cause of infertility
challenges and offering the most effective treatment options. We provide a
full range of services depending on your needs. These can include
counseling, ofce hysteroscopy, inseminations, ovulation induction,
superovulation, in vitro fertilization, intracytoplasmic sperm injection, pre-
implantation genetic counseling and screening, and more.

INFERTILITY EVALUATION & TREATMENT

For some couples, becoming pregnant is a challenge. Infertility is the inability
to get pregnant despite having frequent, unprotected sex for at least a year.
Although many couples are really subfertile rather than infertile, they are
often considered infertile when they haven't conceived despite trying for one
year. This is usually the point to start seeking medical support as the monthly
chance of pregnancy is 4 percent or less after one year. Faster evaluation
may be appropriate for women over the age of 35, when there are known
medical conditions that interfere with fertility, or if trying to conceive causes
signicant stress.
Infertility is not just a woman's problem. Causes can involve one or both
partners. In fact, the incidence of sperm problems is on the rise, accounting
for up to half of infertility causes, according to some studies. In other
instances, couples want to plan ahead to ensure fertility after a disease, such
as cancer.
Among others, our services
include:
Ÿ Flexible ofce hysteroscopy
Ÿ Fertility preserving surgery for
gynecologic conditions
Ÿ Laparoscopic and open tubal
reanastomosis
Ÿ Follicular monitoring
Ÿ Intrauterine insemination (IUI)
Ÿ In vitro fertilization (IVF), including
Intracytoplasmic sperm injection (ICSI)
Ÿ Preimplantation genetic diagnosis (PGD) and screening (PGS)
Ÿ Gryopreservation of embryos, unfertilized eggs, and sperm
Ÿ Fertility preservation for cancer patients
Ÿ Donor egg and gestational carrier IVF

Care-Commitment-Excellence
After careful examination, we identify
potential barriers to conception and discuss
how to evaluate and treat them in the most
effective manner, realizing that cost is always
o n e f a c t o r. We a r e c o m m i t t e d t o
personalized care and unparalleled service
when promoting fertility. That commitment
coupled with our years of experience have
led to proven results.

Additionally, we treat other reproductive

disorder including:
Ÿ Hirsutism/androgen excess Ÿ Premature ovarian failure
Ÿ Hyperprolactinemia Ÿ Recurrent pregnancy loss
Ÿ Menstrual disorders Ÿ Uterine myomas (broids)
Ÿ Polycystic ovary syndrome Ÿ Delayed puberty
 TREATMENT METHODS AND TECHNIQUES
Male Evaluation
In up to 30 of the infertile couples male factor is important. We evaluate this
by performing a SEMEN ANALYSIS.

IVF
In Vitro Fertilization: We would stimulate ovaries to produce many eggs,
which are then retrieved and inseminated with partner's sperms. Fertilized
eggs now called an embryo is cultured in highly controlled incubators.
Resulting embryos are replaced into the uterus for implantation.

ICSI
Intracytoplasmic sperm injection is an advanced technique utilized to achieve
fertilization by injecting a selected sperm into a mature egg. This specialized
technique can be especially useful for couples with very low sperm counts.

Assisted Hatching
The embryo after culture is encased in a protective layer called zona pellucid.
In selected cases we open this protective coating to give the embryo
increased chances of implantation.

Blastocyst Culture
In selected cases, we culture the embryos to an advanced stage and perform
a day 5 transfer thus allowing us a greater ability to select the best embryos
and improving the success rates of implantation.

Embryo Cryopreservation
Embryo Cryopreservation also called embryo freezing allows us to freeze any
extra embryos in a cycle and use them for transfer in a subsequent 'frozen
cycle'. With improved freezing techniques some studies are reporting better
pregnancy rates in selected patients in frozen cycles as a result of more
receptive endometrial lining.

Semen Cryopreservation
Sperm freezing frequently utilized in cancer patients, for sample to be utilized
once battle against cancer has been won. Many patients undertake social
freezing such as busy work schedule, frequent travelling, overseas
deployment, where sperms sample can be thawed and used for insemination
at a time when female partner is ready. In addition sperms retrieved after
vasectomy, and testicular sperms obtained by TESE can be frozen and used
later on as well. Research shows that sperm that have been frozen and
thawed have promising fertilization rates and are no more likely to result in
birth defects than freshly ejaculated sperm.

Fertility Preservation
Oocyte (egg) freezing is an integral part of assisting cancer patients preserve
their reproductive potential before they start chemotherapy that may
damage the remaining eggs. In addition vast number of career oriented
women are preserving their eggs at a younger age when eggs have a lesser
chance of genetic mutations, and before their ovarian reserve gets
diminished as a result of age. We use an advanced technique called
vitrication to freeze the eggs, that gives us higher survival rates upon
thawing the eggs, and subsequently better pregnancy rates than many other
centers, that may be using older techniques.

Pre-Implantation Genetic Counseling and Screening

With a family history of genetic disease, advancing age, previous IVF failures,
PGD/PGS can help in having a healthy successful pregnancy.
Recurrent Pregnancy loss
Loss of pregnancy in early weeks frequently has an underlying anatomical or
endocrinological reason. Identifying and xing these defects, can improve
your chances of a successful pregnancy by two to three folds. Our physicians
will undertake a thorough evaluation and make a plan for an improved
outcome for your future pregnancies.

Pregnancy after having a

tubal ligation
It is still possible to have a child by either a
tubal reversal, or in vitro fertilization. As a
matter of fact you have a better chance of
success than someone of your age, who
has a history of infertility for other
reasons, of the same age, of a successful
pregnancy with assisted reproductive
technologies.

Vasectomy in Past
Can I have child? certainly! Through sperm retrieval from Vas deferens, and
In Vitro Fertilization, Our experts can help you achieve your dreams.

PCOS: Polycystic Ovarian Syndrome

PCOS has a genetic component. We can help you achieve pregnancy and
healthier lifestyle while living with PCOS through medical and surgical
options.

Endometriosis
This horrible disease can't only cause pain but can also be the cause of
Infertility in many cases. Endometriosis surgery can get very complex and
requires specialized surgical skills to achieve optimal outcomes. After surgery
aggressive medical therapy is needed to overcome the effects of
endometriosis and help you achieve an improved quality of life as well as a
pregnancy.
In vitro fertilisation (IVF)
SHIFA FERTILITY CENTER
Rizwan Malik
M.D., MSc, FACOG, FACS (USA)
Board Certied

Dr. Malik completed Bachelor of Science in

Biomedical and Electrical Engineering with honors
from University of Southern California School of
Engineering, Los Angeles, USA. He earned his
doctorate of Medicine - MD degree from Boston
University School of Medicine, Boston MA / USA.
Dr Malik completed his residency in Obstetrics &
Gynecology from University of Miami School of
Medicine, sub-specialty Fellowship Training in
Reproductive Endocrinology and Infertility from University of South Alabama,
and Master in Embryology and Andrology from Eastern Virginia Medical
School, Jones Institute for Reproductive Medicine.
Dr Malik is a faculty member at Indiana University School of Medicine,
Fellow of American College of Obstetrics and Gynecology as well as
American College of Surgeons. He is an active member of American College
of Obstetrics and Gynecology as well as American Society of Reproductive
Medicine.
Dr. Malik holds a Board certication from American Board of Obstetrics and
Gynecology.

Botros RMB Rizk

M.D., MA, FRCOG, FRCS, HCLD, FACOG, FACS

Professor and Head, Division of Reproductive

Medicine & Infertility, University of South Alabama,
Mobile AL, is trained in Infertility with Sr Roberts
Edwards, at Bourn Hall, UK. He is author of over
100 peer reviewed articles, editor of over sixteen
textbooks in Infertility Reproductive Endocrinology
and Ultrasound.

Clinic: Center for IVF & Reproductive Medicine,

Shifa International Hospital, H-8/4, Islamabad.
Phone: +92 310 5847521, +92 51 846 4646
E-mail: afc@shifa.com.pk
Your Dreams
are our
Expertise!

CENTERS, USA LLC

Shifa Fertility Centre

Sector H-8/4, Islamabad - Pakistan
Ph. +92 310 5847521, +92 51 846 4646
or Email: afc@shifa.com.pk