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Name/ NIM : Elsa Novitasari / 190612642944

Nadia Regita Ayu Cahyani / 190612642931

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The Science Behind HIV / AIDS


HIV / AIDS has caused the loss of human life of around 39 million worldwide,
despite efforts to prevent and treat it. In HIV transmission, the virus enters the bloodstream,
semen, vaginal fluid, and breast milk through infected fluid. HIV generally attacks white
blood cells, especially T - Helper cells that work for the body's immunity and fight infections.
In the body, glycoproteins cover the infected part of the body by mutating frequently. Then, it
attaches to T cells that make HIV blend with the membrane.

Because HIV is a retrovirus, RNA is transcribed into DNA. DNA then joins into the
host cell genome. During the initial stage of replication, commonly called the Lately Period: a
person has no initial symptoms of HIV for 8 years. This HIV disease, if left untreated, HIV
eventually kills T cells infected with HIV, so the number of T cells decreases which
subsequently becomes AIDS (Acquired Immune Deficiency Virus).

With AIDS, the immune system becomes more vulnerable to cancer and opportunistic
infections such as pneumonia. AIDS actually does not cause people to die. However, diseases
that enter the body that make people die. Drugs that help fight AIDS infection are primordial
virgins, anti-retroviral drugs that slow the virus by blocking certain enzymes that the virus
needs to control itself. While for people who are at high risk of contracting HIV, they can use
the Axis profile or PeEP which has the same efficacy as anti-retroviral drugs. There are some
people who are immune to the virus, because of a mutation bound to the T-cell in their body.

References :

https://youtu.be/FDVNdn0CvKI

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