Is fibromyalgia masking your patient’s AS? Although separate syndromes with different mechanisms, Fibromyalgia signs and symptoms may overlap with those of AS* Fibromyalgia tender points** AS presentation™ Overlapping signs and symptoms™* Nocturnal back pain \ Morning stiffness a Disturbed sleep Neck pain Pain with pressure \ Fatigue IO In one study (N=98), 10% of patients with fibromyalgia met ASAS criteria for ‘SpA based on MRP Up to 25% of patients with AS have coexisting fibromyalgia* Nota comprehensive list of sgns/symptoms. AS ankylosing sponeyits; ASAS=Assessment of SpandyLothls international Soity: MRl=magnetic resonance imaging: SpA=spandycathitis,CRP levels can help identify patients with coexisting fibromyalgia and AxSpA Nearly 1/3 of fibromyalgia patients have elevated CRP? ‘AxSpA-axial spondyloarthrits; CRP=C-reactve protein References: 1. Ablin JN, Eshed |, Berman M, et al. Prevalence of axial spondyloarthritis among patients with fibromyalgia: a magnetic resonance imaging study with application of the Assessment of SpondyloArthris international Sccety classification eriteria, Arthritis Caro Res (Hoboken) 2017:69(5)724-728, 2. Chakrabarty 8, Zoorab R. Fibromyalgia. Am Fam Physician, 2007,76(2:247-254, 3, Lovies Ru, Baeten DL. Differences in pathophysiology between rheumatoid arthritis and ankylosing spondylitis. Clin Exp Rheumatol. 2008;27(4 supa '535}:S10-S14, 4, Mease PU. Fibromyalgia, a missed comorbicity in spondyloarthitis: prevalence and impact on assessment and treatment. (Curr Opin Rheumata. 2017;28(4:304-310, & Novartis Novartis Pharmaceuticals Corporation ast Hanover, Hew Jersey (79361080 (© 2018 Novartis as 91389783