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Presented by-
SUPRIYA SUMAN
PharmD 4th year
Roll no.-15
INTRODUCTION:-
LIQUID
BIPHASIC MONOPHASIC
INSTILLED
USED IN APPLICATION
INTO BODY LINCTUS ELIXIR SYRUP
MOUTH ON THE SKIN
CAVITIES
THROAT MOUTH
NASAL SPRAY NASAL DROP EAR DROP GARGLES LOTION LINIMENT
PAINT WASH
Formulation /Manufacturing procedure
COMPONENTS
• API
• Vehicle
Aqueous vehicles: Water, Aromatic Water,
Alcohol, glycerine, Propylene Glycol.
Oily vehicles: Vegetable oils, mineral oils,
organic oily bases or emulsified bases.
COMPONENTS
• Surfactant
Solubilising agents – eg- Polysorbate 80.
Flocculating agent – eg- gum acacia,wool fat,methylcellulose,
Wetting agent – eg- Tweens 80, spans ,SLS.
Emulsifying agents
Antifoaming agents –eg- Castor oil, fatty acids.
CONTINUE.....
• Colouring agent – example- coal tar dyes such as amaranth
(red),caramel(brown),indigo(blue), napthol(black).
• Flavouring agents -
Tinctures- tincture lemon, and tincture ginger .
Fruit juices- raspberry juice , wild cherry.
Essence- vanilla, orange.
• Preservative –example-methyl paraben , sodium benzoate,
benzoic acid.
• Antioxidant agent-example- BHA,BHT
PROCEDURE
make up to
In ¾ th of add any liquid
Dissolve solid the volume by
vehicle ingredient
vehicle
CONTINUE....
Transfer content
Make it up to the Add any liquid
mortar to measuring
volume by vehicle ingredient
cylinder
CONTINUE...
• For indiffusible solid:-
Transfer the
Add vehicle for Add other liquid
mixture into
required volume ingredient
measuring cylinder
CONTINUE ...
• Biphasic dosage form
Suspension
2type of component