LAST MINUTE REVISION POINTS (LMRP) for

JIPMER NOVEMBER 2017

1. Liver is held in its position by Intra-abdominal pressure and tone of muscles, Peritoneal fold and
Attachment of hepatic veins to IVC.
2. Injury to facial nerve below geniculate ganglion and above stylomastoid foramen level causes injury to
chordatympanic branch of facial nerve which leads to loss of taste sensation in anterior 2/3 of tongue, loss
of submandibular and sublingual gland secretions.
3. Root of the mesentery crosses the following 5 structures: 3rd part of the duodenum, Aorta, Inferior
vena cava, Right ureter, Right psoas major.
4. Azygos lobe is a congenital variation of the upper lobe of the right lung.
5. Ligament maintaining Atlantoaxial stability is: Transverse ligament.
6. Myelination in intrauterine period starts at: 20 weeks.
7. Wrist can be adducted more than abduction because: Ulnar styloid process placed more proximally .
8. Cervical pleura is a continuation of Costal pleura.
9. Deep inguinal ring is derived from: Fascia transversalis.
10. In-turned ischial spines are features of male hip bone.
11. Gray ramus communicates is grey in colour due to: Post- ganglionic non-myelinated sympathetic fibres.
12. Fast pain –Aδ-type fibers, Slow pain- C-type fibers, Heat and Cold sensation- by A delta and C fibers .
13. Enterohepatic circulation in GIT occurs at the level of: Terminal ileum .
14. According to Starling law, force of contraction is directly proportional to: End diastolic length of muscle
fibres .
15. Contractility is a variable independent from loading conditions, whereas the ejection fraction can be
affected by changes in preload and afterload.
16. Lipoprotein A Lp(a) consists of 1 mol of LDL attached to a 1 mol of apo(a). Apo(a) shows structural
homologies to plasminogen.
17. Glucose uptake in skeletal muscles, heart and adipose tissues is mediated by GLUT 4 which requires
insulin.
18. Acetyl Co-A carboxylase is the rate- limiting step of fatty acid synthesis. Fatty acid synthesis. occurs
during well fed state. Insulin is the predominant hormone during well-fed state.
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19. Function of pseudouridine arm of t RNA: For t-RNA and attaches to it.
20. Enzyme required for synthesis of both ketone bodies and cholesterol is: HMG CoA synthase.
21. Pyridoxine is a co- factor for : Decarboxylation reactions.
22. Oxygen dependent reactions in liver take place in : Zone 1.
23. Catabolism of long chain fatty acids occur in: Mitochondria.
24. Rate limiting step in de novo purine synthesis is PRPP glutamine amidotransferase .
25. Insulin: Acts on intrinsic tyrosine kinase receptors .
26. Carbohydrate moiety of Antigen recognizing site in RBC used for blood grouping is: Fucose .
27.Function of Golgi apparatus: Storing and packing of proteins.
28. Fusion inhibitor approved for used in HIV is : Enfuvirtide
29. Heparin “clears” lipemic plasma in vivo by causing the release of lipoprotein lipase into the circulation.
30. Lenalidomide may increase the risk of deep venous thrombosis and pulmonary embolus . Concurrent
use of corticosteroids may further increase this risk.
31. Diuretics (Thiazide, Furosemide) by causing Na+ loss promote proximal tubular reabsorption of Na+ as
well as Li+ causing plasma levels of lithium rise.
32. Lab monitoring of a patient on low molecular weight heparin (LMWH) is done by estimating: Anti-Xa.
33. N acetyl cysteine replenishes the glutathione stores of liver and prevents binding of the toxic
metabolites to the other cellular constituents.
34. Adverse Effects of Ethambutol are:
 Low visual acuity, defects in colour vision and field defects due to optic neuritis
 Nausea
 Rashes
 Fever
 Neurological manifestations
 Hyperuricemia
35. Mechanism of action of alendronate is: Inhibits osteoclasts.
36. Alteration of Penicllin binding proteins is responsible for both low level and high level resistance seen in
Strepococcus pneumoniae to penicillin G and Staphylococcus to nafcillin.
37. Negri bodies, found in pyramidal neurons of the hippocampus and Purkinje cells of the cerebellum.
38. Most severe form of hereditary spherocytosis is caused by the mutation of: Alpha spectrin .
39. A specific feature of apoptosis is the activation of several members of a family of cysteine proteases
named caspases.
40. Antigen used in the interferon gamma release assay (IGRA) for the diagnosis of latent TB is: ESAT6.
41.Characteristics of Staphylococcus Aureus:
 Gram positive cocci
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  Arranged in clusters
 Non-motile
 Catalase positive
 OXIDASE negative
42. Northern blot technique is used in the detection of: RNA.
43. Internal putrefaction earliest seen in: Undersurface of liver.
44. Drooling of saliva is pathognomonic of: Antemortem hanging .
45. According to MTP act, abortion can be done till: 20 weeks.
46. Correlation co-efficient of 0.5 indicate:Weak association.
47. The colour of bag used to dispose sharp wastes Is: Blue white translucent .
48.Preventing obesity becomes primordial prevention for most of the Non –communicable diseases.
49. Cold Spots on bone scan causes are: Multiple myeloma, Bone infarction .
50. Timely primary percutaneous coronary intervention (PCI) is the preferred therapy for ST-segment
elevation myocardial infarction (STEMI).
51. Most sensitive test for diagnosis of H. Pylori: Rapid urease test .
52. Number connection test is done to detect: Hepatic encephalopathy .
53. Reversible myocardial ischemia is best diagnosed by: PET scan.
54. Conglomerate bodies found in: Sarcoidosis.
55. Appropriate antibiotic therapy instituted before the 9 th day of symptoms of acute GAS pharyngitis is
highly effective in preventing 1st attacks of acute rheumatic fever from that episode.
56. Hepatitis B Vaccination can decrease the incidence of Hepatitis B and thus Hepatocellular carcinoma.
57. The SMA is the most commonly involved vessel in acute mesenteric ischemia.
58. Source of bleeding ulcer on lesser curvature of stomach is: Right gastric artery & left gastric artery .
59. The ideal time when invertogram should be done in a newborn : After 6 hours
60. Causes of SVCS are : Squamous cell and Small cell lung Ca,Lymphoma,Thrombosis following intra
venous catheter use, Metastasis from Testicular and Breast Ca.
61. Second only to the spleen, injury to the liver is extremely common after blunt abdominal trauma.
62. Intussuception is frequently associated with: Sub mucosal lipoma.
63.The Alkali Denaturation Test
 Used to differentiate fetal or neonatal blood from maternal blood (Qualitative).
 Positive test indicates that blood is of fetal origin.
 Negative test indicates that the blood is of maternal origin.
64. Absolute indications for therapeutic termination in maternal heart disease during pregnancy :
 Primary pulmonary hypertension.
 Eisenmenger’s syndrome.
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  Pulmonary veno-occlusive disease.
65. Varicella immunoglobulin to be given in: Non immunised mother exposed to varicella infection .
66. Drug of choice in a pregnant woman with Chamydia trachomatis infection is: Amoxicillin .
67. HAIR-AN syndrome. Patient with PCOS characterized by hyperandrogenism, insulin resistance and
acanthosis nigricans.
68. Possible Late Sequelae of PCOS:
 Diabetes mellitus
 Endometrial hyperplasia and carcinoma
 Hypertension and cardiovascular disease
 Obstructive sleep apnea.
69. Light bulb sign in X-ray shoulder is seen in: Post dislocation of shoulder .
70. Pointing index in supracondylar fracture is due to : Anterior interosseous nerve injury .
71. Best management of open fracture is: Debridement .
72.Increase in bone girth occurs by appositional bone formation by generative cells in the deepest layer of
periosteum.
73. Hook of hamate in a hyperextended hand causes compression of: Ulnar nerve.
74. The Classic O’Donoghue Triad:
 Characterized by an injury to:
- The anterior cruciate ligament
- The medial collateral ligament (or tibial collateral ligament)
- The medial meniscus.
75. Achondroplasia typically manifests at birth with short limbs, a long narrow trunk, and a large head with
midfacial hypoplasia and prominent forehead and skeletal radiographs confirm the diagnosis.
76. Treatment of choice in newborn with club foot: Both manipulation and splint.
77. Function of cruciate ligaments: Prevents anteroposterior instability.
78. In children, cavitation is most commonly caused by Streptococcus pneumoniae and less frequently by
Aspergillus spp., Legionella spp. And Staphylococcus aureus..
79. Weight for height/ WHO grade for acute severe malnutrition : Z score less than -3
80. Bedwetting is considered normal in girls and boys till the age of: 4 and 5 years respectively .
81. Chromium→ Potentiates the action of insulin : And its DEFICIENCY causes:
 Impaired glucose tolerance
 Peripheral neuropathy
 Encephalopathy.
82.COACH syndrome (cerebellar vermis hypoplasia, oligophrenia, congenital ataxia, coloboma, and hepatic
fibrosis).
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83. WHO grade of a HIV child with parotid enlargement: Stage 2.
84. CHF develops in infants with large VSDs, but usually not until 6 to 8 weeks of age.
85. Sevoflurane is favoured in paediatric practice for gaseous induction, but desflurane or isoflurane are
marginally the preferred agents for maintenance of anesthesia in children with Liver disease undergoing
major abdominal surgery.
86. Stereotactic Radiosurgery: It is a type of external beam radiation therapy.
87. A patient with a perceptional disorder is able to see an object without any external stimulus. This
phenomenon is known as: Hallucination .
88. The middle ear communicates with the mastoid area posteriorly and the nasopharynx (via the
pharyngotympanic tube) anteriorly .
89. Inferior tympanic artery is a branch of : Ascending pharyngeal artery .
90. The collecting duct develops from the ureteric bud and is thus technically not part of the nephron.
91. Mesorectal Fascia : Contains
 Superior rectal artery and its branches.
 Superior rectal vein and tributaries.
 Lymphatic vessels and nodes along the superior rectal artery.
 Branches from the inferior mesenteric plexus which descend to innervate the rectum.
 Loose adipose connective tissue.
92. Posterior Cricoarytenoid: The only muscle produce abduction of vocal cord (open the rima glottides).
93. Retropharyngeal space situated behind the pharynx. It extends from the base of skull to the infrahyoid
region, where it continuous with retrovisceral space (retrovisceral space extends upto superior
mediastinum/bifurcation of trachea).
94. Claudius Cells are considered as supporting cells within the Organ of Corti in the Cochlea.
95. Secretory phase of endometrium is due to which hormone : Progesterone.
96. Most common progesterone metabolite in urine : Pregnanediol .
97. Together with endothelial cells of blood vessels within the fascicle, perineurial cells constitute part of
the blood-nerve barrier.
98. One molecule of DPG is bound per hemoglobin tetramer, in its central cavity, in the T-form, when the
space between the H-helices of the beta chains is just wide enough to accommodate it.
99. Utilization of ketone bodies by :
 Heart
 Brain (especially when starving).
 Skeletal muscle.
 Renal cortex.
Ketones are NOT utilized by:
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  RBC- Since it does NOT contain mitochondria.
 Liver- Since it does NOT contain thiophorase enzyme.
100. Only thiazide used in renal failure when GFR is less than 30-40 ml/min: Metolazone .

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