 question_answer1) Which one of the following is a hereditary disease?

[NDA]

A) Cataract

B) Haemophilia

C) Pellagra

D) Osteoporosis

 question_answer2) Which one of the following statements is correct? Cretinism is a

human disorder which is due to the under secretion of: [NDA]

A) Adrenalin hormone

B) Cortisone hormone

C) Glucagon hormone

D) Thyroxin hormone

 question_answer3) Which one of the following is not a genetic disorder? [NDA]

A) Colour blindness

B) Down?s syndrome

C) Haemophilia

D) Xerophthalmia

 question_answer4) Which one of the following genetic diseases is sex-linked? [IAS

Prelim]

A) Royal haemophilia

B) Tay-Sachs disease

C) Cystic fibrosis

D) Hypertension
 question_answer5) A mother of blood group O has a group O child. What could be the
blood group of father of the child? [CDS]

A) Only O

B) A or B or O

C) A or B

D) Only AB

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 question_answer6) Between which one of the following sets of blood groups, is the
blood transfusion possible? [CDS]

A) A and O

B) B and A

C) A and AB

D) AB and 0

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 question_answer7) Which one among the following is not correct about Down's
syndrome? [CDS]

A) It is a genetic disorder

B) Effected individual has early ageing

C) Effected person has mental retardation

D) Effected person has furrowed tongue with open mouth

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 question_answer8) Haemophilia is a genetic disorder which lead to [IAS]

A) decrease in haemoglobin level

B) rheumatic heart disease

C) decrease in WBC

D) non-clotting of blood

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 question_answer9) Which one of the following techniques can be used to establish the
paternity of a child I? [IAS]

A) Protein analysis

B) Quantitative analysis of DNA

C) Chromosome counting

D) DNA fingerprinting

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 question_answer10) Number of chromosome in a normal human body cell is [SSC]

A) 43

B) 44

C) 45

D) 46

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 question_answer11) Which one of the following genetic disease is sex-linked? [IAS]

A) Royal haemophilia

B) Tay-Sachs disease

C) Cystic fibrosis
D) Hypertension

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 question_answer12)

Assertion [A]: In human beings, the female play a major role in determining the sex
of the offspring.
Reason (R): Women have two X-chromosomes. [IAS]

A) Both A and R are true and R is the correct explanation of A

B) Both A and R are true, but R is not a correct explanation of A

C) A is true, but R is false

D) A is false, but R is true

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 question_answer13) Variation can be brought about by

A) sexual reproduction

B) copying of DNA

C) adjusting with environment

D) All of the above

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 question_answer14) The sex of the child in humans primarily depends on

A) X chromosome of female part

B) X and Y chromosome of male part

C) Both [a] & [b]

D) None of the two

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 question_answer15) State 'T' for True option and F for False option and choose the
correct option at the end

A. We have a single pair of sex chromosomes in all cells.

B. Autosomes are 22 pairs of chromosomes.
C. The human karyotype represents the pair of chromosome in a cell
D. There are 46 Chromosomes as autosomes.

A) TFTF

B) TTTF

C) TFFF

D) TTFF

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 question_answer16) In human beings, a recessive gene can express it in homozygous

condition as in

A) Autosome

B) X-chromosome of male

C) X-Chromosome of females

D) An autosome or X-Chromosome

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 question_answer17) Genetics is the study of-

A) Inheritance

B) Cell structure

C) Only plants

D) Only animals
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 question_answer18) Mendel Laws of Heredity were rediscovered by

A) Charles Darwin

B) Lamark

C) Devries correns and Tschermark

D) Morgan

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 question_answer19) Hereditary characteristics are passed on from parents to off spring

chiefly through

A) gametes

B) enzymes

C) genes

D) centrosomes

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 question_answer20) Gene is made of which chemical

A) D.N.A.

B) R.N.A.

C) protein

D) enzyme

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 question_answer21) Consider the following statements:

A. Sex is determined by different factors in various species.

 B. Exchange of genetic material takes place in asexual reproduction.
Which of these statement(s) is/are correct?

A) A only

B) B only

C) Both A and B

D) Neither A nor B

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 question_answer22) From heredity point of view which marriage is not suitable

A) Man Rh (-) and Woman Rh (+)

B) Both Rh (+)

C) Both Rh (-)

D) Man Rh (+) and Woman Rh (-)

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 question_answer23) In animals sex determination is due to

A) X-chromosome

B) Y-chromosome

C) A-chromosome

D) B-chromosome done

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 question_answer24) A complete set of chromosomes inherited as a unit from one

parent, is known as

A) Karyotype
B) Gene pool

C) Genome

D) Genotype

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 question_answer25) The ratio of phenotypes in

F2
of a monohybrid cross is

A) 3:1

B) 1:2:1

C) 9:3:3:1

D) 2:1

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 question_answer26) Sickle cell anaemia is

A) caused by substitution of valine by glutamic acid in the beta globin chain of

haemoglobin.

B) caused by a change in a single base pair of DNA.

C) characterized by elongated sickle like RBCs with a nucleus.

D) an autosomal linked dominant trait.

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 question_answer27) Mutations can be induced with

A) infrared radiations

B) I AA
C) ethylene

D) gamma radiations

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 question_answer28)

Column-I Column-II
A. ABO blood groups I. Dihybrid cross
B. Law of segregation cross II. Monohybrid
C. Law of Independent assortment III. Base pairs substitution
D. Gene mutation IV. Multiple allelism

A) A-II; B-I; C-IV; D-III

B) A-IV; B-I; C-II; D-III

C) A-IV; B-II; C-I; D-III

D) A-II; B-III; C-IV; D-I

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 question_answer29)

Column-I Column-II
A. Incomplete dominance I. Drosophila
B. Mendelian disorder II. Antirrhinum sp.
C. Transforming principle III. Griffith
D. Dihybrid cross IV. Haemophilia

A) A-I; B-IV; C-III; D-II

B) A-IV; B-II; C-III; D-I

C) A-II; B-III; C-IV; D-I

D) A-II; B-IV; C-III; D-I

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 question_answer30) First transgenic plant -

A) Potato

B) Tomato

C) Tobacco

D) Maize

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 question_answer31) The bacteria generally used for genetic engineering is

A) Agrobacterium

B) Bacillus

C) Pseudomonas

D) Clostridium

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 question_answer32) Bacillus thuringiensis (Bt) strains have been used for designing
novel -

A) Bio-metallurgical techniques

B) Bio-insecticidal plants

C) Bio-mineralization processes

D) Bio-fertilizers

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 question_answer33) Which of the following is false for Bt transgenic plant -

A) Disease resistance

B) Prepared by Bacillus thuringiensis

C) It is recombinant type

D) No such plant is known

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 question_answer34) First cloned animal is -

A) Dog

B) Molly

C) Dolly sheep

D) Polly sheep

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 question_answer35) Genetically engineered human insulin is prepared by using-

A) E. coli

B) Rhizopus

C) Pseudomonas

D) Yeast

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 question_answer36) Golden rice is a transgenic crop of the future with the following
improved trait -

A) High lysine (essential amino acid) content

B) Insect resistance
C) High protein content

D) High vitamin-A content

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 question_answer37) Plasmid has been used as vector because

A) both its ends show replication.

B) it can move between prokaryotic and eukaryotic cells.

C) it is circular DNA which have capacity to join to eukaryotic DNA.

D) it has antibiotic resistance gene.

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 question_answer38) Which of the following is known as specific molecular scissors?

A) Ligase

B) Helicase

C) Restriction endonuclease

D) DNA polymerase

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 question_answer39) The enzyme used for joining two DNA fragments is called

A) ligase

B) restriction endonuclease

C) DNA polymerase

D) gyrase

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 question_answer40) Which of the following statement is incorrect regarding PCR?

A) In PCR, two primers are used.

B) Taq DNA polymerase is related for PCR.

C) Taq DNA polymerase is not thermostable.

D) Multiple copies of gene can be synthesized in PCR.