(Valdiglesias et al., 2016)(Maria Dhivya et al., 2016)
(Wideman, Zautra and Edwards, 2014)
(Michalak et al., 2016)
(Moreno-Vega et al., 2012)
(Agotegaray et al., 2017)
Acosta-Torres, L. S. et al. (2012) ‘Cytocompatible antifungal acrylic resin containing silver
nanoparticles for dentures’, International Journal of Nanomedicine, 7, pp. 4777–4786. doi: 10.2147/IJN.S32391. Adibkia, K. et al. (2014) ‘Antimicrobial activity of the metals and metal oxide nanoparticles’, Materials Science and Engineering: C, 44, pp. 278–284. doi: 10.1016/j.msec.2014.08.031. Agotegaray, M. A. et al. (2017) ‘Magnetic nanoparticles for drug targeting: From design to insights into systemic toxicity. Preclinical evaluation of hematological, vascular and neurobehavioral toxicology’, Biomaterials Science, pp. 772–783. doi: 10.1039/c6bm00954a. Arteche Pujana, M. et al. (2013) ‘Biodegradable chitosan nanogels crosslinked with genipin’, Carbohydrate Polymers. Elsevier Ltd., 94(2), pp. 836–842. doi: 10.1016/j.carbpol.2013.01.082. Asadi, Z. et al. (2017) ‘Investigation of the complex structure, comparative DNA-binding and DNA cleavage of two water-soluble mono-nuclear lanthanum(III) complexes and cytotoxic activity of chitosan-coated magnetic nanoparticles as drug delivery for the complexes’, Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. Elsevier B.V., 178, pp. 125–135. doi: 10.1016/j.saa.2017.01.037. Bae, J. E. et al. (2011) ‘The effect of static magnetic fields on the aggregation and cytotoxicity of magnetic nanoparticles’, Biomaterials. Elsevier Ltd, 32(35), pp. 9401–9414. doi: 10.1016/j.biomaterials.2011.08.075. Cao, M. et al. (2016) ‘Magnetic iron oxide nanoparticles accelerate osteogenic differentiation of mesenchymal stem cells via modulation of long noncoding RNA INZEB2’, Nano Research, pp. 626– 642. doi: 10.1007/s12274-016-1322-4. Coral, D. F. and Jenny A Mera, J. A. M. (2017) ‘Una Guía para el estudio de nanopartículas magnéticas de óxidos de hierro con aplicaciones biomédicas. Parte II’, Ingeniería y Ciencia, 13(26), pp. 207–232. doi: 10.17230/ingciencia.13.26.8. Costa, B. F. O. et al. (2016) ‘Development of a biocompatible magnetic nanofluid by incorporating SPIONs in Amazonian oils’, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 172, pp. 135–146. doi: 10.1016/j.saa.2016.04.022. Dobson, J., McBain, S. C. and Yiu, H. H. P. (2008) ‘Magnetic nanoparticles for gene and drug delivery’, International Journal of Nanomedicine, pp. 169–180. doi: 10.2147/IJN.S1608. Fatemi, M. et al. (2018) ‘Extracellular biosynthesis of magnetic iron oxide nanoparticles by Bacillus cereus strain HMH1: Characterization and in vitro cytotoxicity analysis on MCF-7 and 3T3 cell lines’, Journal of Biotechnology. Elsevier, 270(January), pp. 1–11. doi: 10.1016/j.jbiotec.2018.01.021. Gaharwar, U. S., Meena, R. and Rajamani, P. (2017) ‘Iron oxide nanoparticles induced cytotoxicity, oxidative stress and DNA damage in lymphocytes’, Journal of Applied Toxicology, pp. 1232–1244. doi: 10.1002/jat.3485. Gholoobi, A. et al. (2017) ‘Biopolymer-mediated synthesis of Fe3O4 nanoparticles and investigation of their in vitro cytotoxicity effects’, Journal of Molecular Structure. Elsevier B.V, 1141, pp. 594–599. doi: 10.1016/j.molstruc.2017.04.024. Gorobets, O., Gorobets, S. and Koralewski, M. (2017) ‘Physiological origin of biogenic magnetic nanoparticles in health and disease: From bacteria to humans’, International Journal of Nanomedicine, 12, pp. 4371–4395. doi: 10.2147/IJN.S130565. Gu, N. et al. (2016) ‘Response of MAPK pathway to iron oxide nanoparticles in vitro treatment promotes osteogenic differentiation of hBMSCs’, Biomaterials, pp. 11–20. doi: 10.1016/j.biomaterials.2016.02.004. Hapuarachchige, S. et al. (2016) ‘Non-temperature induced effects of magnetized iron oxide nanoparticles in alternating magnetic field in cancer cells’, PLoS ONE, 11(5), pp. 1–12. doi: 10.1371/journal.pone.0156294. Hoskins, C., Cuschieri, A. and Wang, L. (2012) ‘The cytotoxicity of polycationic iron oxide nanoparticles: Common endpoint assays and alternative approaches for improved understanding of cellular response mechanism’, Journal of Nanobiotechnology. BioMed Central Ltd, 10(1), p. 15. doi: 10.1186/1477-3155-10-15. Jayash, S. N. et al. (2016) ‘In vitro evaluation of osteoprotegerin in chitosan for potential bone defect applications ’, PeerJ, p. e2229. doi: 10.7717/peerj.2229. Journal, D. et al. (2012) ‘BIOGENIC SYNTHESIS OF Fe 3 O 4 NANOPARTICLES USING TRIDAX PROCUMBENS LEAF EXTRACT AND ITS ANTIBACTERIAL ACTIVITY’, Digest Journal of Nanomaterials and Biostructures Vol., 7(3), pp. 1655–1660. Kasner, E. et al. (2013) ‘Fundamentals and Application of Magnetic Particles in Cell Isolation and Enrichment’, pp. 646–656. doi: 10.1002/ana.22528.Toll-like. Kim, J., Hegde, M. and Jayaraman, A. (2010) ‘Co-culture of epithelial cells and bacteria for investigating host-pathogen interactions’, Lab on a Chip, 10(1), pp. 43–50. doi: 10.1039/b911367c. Kocaman, A. Y. and Topaktas, M. (2007) ‘In Vitro Evaluation of the Genotoxicity of Acetamiprid’, Environmental and Molecular Mutagenesis, 490(April), pp. 483–490. doi: 10.1002/em. Liakos, I., Grumezescu, A. M. and Holban, A. M. (2014) ‘Magnetite nanostructures as novel strategies for anti-infectious therapy’, Molecules, 19(8), pp. 12710–12726. doi: 10.3390/molecules190812710. López-Marín, L. M. et al. (2010) ‘Biocompatible Metal-Oxide Nanoparticles: Nanotechnology Improvement of Conventional Prosthetic Acrylic Resins’, Journal of Nanomaterials, 2011, pp. 1–8. doi: 10.1155/2011/941561. Maria Dhivya, S. et al. (2016) ‘A Comparative Study on the Biopolymer Functionalized Iron Oxide Nanocomposite for Antimicrobial Activity’, Materials Today: Proceedings. Elsevier Ltd, 3(10), pp. 3866–3871. doi: 10.1016/j.matpr.2016.11.042. Michalak, G. et al. (2016) ‘Magnetic nanoparticles as a drug delivery system that enhance fungicidal activity of polyene antibiotics’, Nanomedicine: Nanotechnology, Biology and Medicine, pp. 2395–2404. doi: 10.1016/j.nano.2016.07.006. Moreno-Vega, A. I. et al. (2012) ‘Polymeric and ceramic nanoparticles in biomedical applications’, Journal of Nanotechnology. doi: 10.1155/2012/936041. Niemirowicz, K. et al. (2016) ‘Magnetic nanoparticles as a drug delivery system that enhance fungicidal activity of polyene antibiotics’, Nanomedicine: Nanotechnology, Biology, and Medicine, 12(8), pp. 2395–2404. doi: 10.1016/j.nano.2016.07.006. Pham, T. et al. (2014) ‘Effect of PEG molecular weight on stability, T2 contrast, cytotoxicity, and cellular uptake of superparamagnetic iron oxide nanoparticles (SPIONs)’, Colloids and Surfaces B: Biointerfaces. Elsevier B.V., 119, pp. 106–114. doi: 10.1016/j.colsurfb.2014.04.027. Polakova, K. et al. (2015) ‘In vitro cytotoxicity analysis of doxorubicin-loaded/superparamagnetic iron oxide colloidal nanoassemblies on MCF7 and NIH3T3 cell lines’, International Journal of Nanomedicine, 10, pp. 949–961. doi: 10.2147/IJN.S72590. Priyadarsini, S., Mukherjee, S. and Mishra, M. (2018) ‘Nanoparticles used in dentistry: A review’, Journal of Oral Biology and Craniofacial Research. Craniofacial Research Foundation, 8(1), pp. 58– 67. doi: 10.1016/j.jobcr.2017.12.004. Ramimoghadam, D., Bagheri, S. and Hamid, S. B. A. (2014) ‘Progress in electrochemical synthesis of magnetic iron oxide nanoparticles’, Journal of Magnetism and Magnetic Materials. Elsevier, 368, pp. 207–229. doi: 10.1016/j.jmmm.2014.05.015. Rastegari, B. et al. (2017) ‘The enzyme-sensitive release of prodigiosin grafted β-cyclodextrin and chitosan magnetic nanoparticles as an anticancer drug delivery system: Synthesis, characterization and cytotoxicity studies’, Colloids and Surfaces B: Biointerfaces. Elsevier B.V., 158, pp. 589–601. doi: 10.1016/j.colsurfb.2017.07.044. Rio Clar, M. (2014) ‘Aplicación de nanopartículas magnéticas de hierro a la eliminación de mercurio del agua’, p. 31. Available at: http://dspace.uib.es/xmlui/bitstream/handle/11201/1143/TFG_QUIMICA_DelRioClarMateu.pdf? sequence=1. Sánchez-Sanhueza, G. (2016) ‘Antimicrobial Nanoparticles in Dentistry. A fad or a real therapeutic option?’, Journal of Oral Research, 5(4), pp. 140–141. doi: 10.17126/joralres.2016.030. Saxena, N. and Singh, M. (2017) ‘Efficient synthesis of superparamagnetic magnetite nanoparticles under air for biomedical applications’, Journal of Magnetism and Magnetic Materials. Elsevier B.V., 429(September 2016), pp. 166–176. doi: 10.1016/j.jmmm.2017.01.031. Silva, L. H. A. et al. (2016) ‘Labeling mesenchymal cells with DMSA-coated gold and iron oxide nanoparticles: Assessment of biocompatibility and potential applications’, Journal of Nanobiotechnology. BioMed Central, 14(1), pp. 1–15. doi: 10.1186/s12951-016-0213-x. Valdiglesias, V. et al. (2016) ‘Are iron oxide nanoparticles safe? Current knowledge and future perspectives’, Journal of Trace Elements in Medicine and Biology, 38, pp. 53–63. doi: 10.1016/j.jtemb.2016.03.017. Wideman, T. H., Zautra, A. J. and Edwards, R. R. (2014) ‘NIH Public Access’, 154(11), pp. 2262–2265. doi: 10.1016/j.pain.2013.06.005.Re-Thinking. Yan, Y. et al. (2018) ‘Development of Fe3O4–HA/PU superparamagnetic composite porous scaffolds for bone repair application’, Materials Letters. Elsevier B.V., 212, pp. 303–306. doi: 10.1016/j.matlet.2017.10.067. Yoneda, M. et al. (2013) ‘Effects of Fe3O4 Magnetic Nanoparticles on A549 Cells’, International Journal of Molecular Sciences, 14(8), pp. 15546–15560. doi: 10.3390/ijms140815546. Zamora-Mora, V. et al. (2017) ‘Chitosan nanoparticles for combined drug delivery and magnetic hyperthermia: From preparation to in vitro studies’, Carbohydrate Polymers. Elsevier Ltd., 157, pp. 361–370. doi: 10.1016/j.carbpol.2016.09.084. Zhong, S. et al. (2017) ‘Folic acid functionalized reduction-responsive magnetic chitosan nanocapsules for targeted delivery and triggered release of drugs’, Carbohydrate Polymers. Elsevier Ltd., 168, pp. 282–289. doi: 10.1016/j.carbpol.2017.03.083.
Acosta-Torres, L. S. et al. (2012) ‘Cytocompatible antifungal acrylic resin containing silver
nanoparticles for dentures’, International Journal of Nanomedicine, 7, pp. 4777–4786. doi: 10.2147/IJN.S32391. Adibkia, K. et al. (2014) ‘Antimicrobial activity of the metals and metal oxide nanoparticles’, Materials Science and Engineering: C, 44, pp. 278–284. doi: 10.1016/j.msec.2014.08.031. Agotegaray, M. A. et al. (2017) ‘Magnetic nanoparticles for drug targeting: From design to insights into systemic toxicity. Preclinical evaluation of hematological, vascular and neurobehavioral toxicology’, Biomaterials Science, pp. 772–783. doi: 10.1039/c6bm00954a. Arteche Pujana, M. et al. (2013) ‘Biodegradable chitosan nanogels crosslinked with genipin’, Carbohydrate Polymers. Elsevier Ltd., 94(2), pp. 836–842. doi: 10.1016/j.carbpol.2013.01.082. Asadi, Z. et al. (2017) ‘Investigation of the complex structure, comparative DNA-binding and DNA cleavage of two water-soluble mono-nuclear lanthanum(III) complexes and cytotoxic activity of chitosan-coated magnetic nanoparticles as drug delivery for the complexes’, Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. Elsevier B.V., 178, pp. 125–135. doi: 10.1016/j.saa.2017.01.037. Bae, J. E. et al. (2011) ‘The effect of static magnetic fields on the aggregation and cytotoxicity of magnetic nanoparticles’, Biomaterials. Elsevier Ltd, 32(35), pp. 9401–9414. doi: 10.1016/j.biomaterials.2011.08.075. Cao, M. et al. (2016) ‘Magnetic iron oxide nanoparticles accelerate osteogenic differentiation of mesenchymal stem cells via modulation of long noncoding RNA INZEB2’, Nano Research, pp. 626– 642. doi: 10.1007/s12274-016-1322-4. Coral, D. F. and Jenny A Mera, J. A. M. (2017) ‘Una Guía para el estudio de nanopartículas magnéticas de óxidos de hierro con aplicaciones biomédicas. Parte II’, Ingeniería y Ciencia, 13(26), pp. 207–232. doi: 10.17230/ingciencia.13.26.8. Costa, B. F. O. et al. (2016) ‘Development of a biocompatible magnetic nanofluid by incorporating SPIONs in Amazonian oils’, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 172, pp. 135–146. doi: 10.1016/j.saa.2016.04.022. Dobson, J., McBain, S. C. and Yiu, H. H. P. (2008) ‘Magnetic nanoparticles for gene and drug delivery’, International Journal of Nanomedicine, pp. 169–180. doi: 10.2147/IJN.S1608. Fatemi, M. et al. (2018) ‘Extracellular biosynthesis of magnetic iron oxide nanoparticles by Bacillus cereus strain HMH1: Characterization and in vitro cytotoxicity analysis on MCF-7 and 3T3 cell lines’, Journal of Biotechnology. Elsevier, 270(January), pp. 1–11. doi: 10.1016/j.jbiotec.2018.01.021. Gaharwar, U. S., Meena, R. and Rajamani, P. (2017) ‘Iron oxide nanoparticles induced cytotoxicity, oxidative stress and DNA damage in lymphocytes’, Journal of Applied Toxicology, pp. 1232–1244. doi: 10.1002/jat.3485. Gholoobi, A. et al. (2017) ‘Biopolymer-mediated synthesis of Fe3O4 nanoparticles and investigation of their in vitro cytotoxicity effects’, Journal of Molecular Structure. Elsevier B.V, 1141, pp. 594–599. doi: 10.1016/j.molstruc.2017.04.024. Gorobets, O., Gorobets, S. and Koralewski, M. (2017) ‘Physiological origin of biogenic magnetic nanoparticles in health and disease: From bacteria to humans’, International Journal of Nanomedicine, 12, pp. 4371–4395. doi: 10.2147/IJN.S130565. Gu, N. et al. (2016) ‘Response of MAPK pathway to iron oxide nanoparticles in vitro treatment promotes osteogenic differentiation of hBMSCs’, Biomaterials, pp. 11–20. doi: 10.1016/j.biomaterials.2016.02.004. Hapuarachchige, S. et al. (2016) ‘Non-temperature induced effects of magnetized iron oxide nanoparticles in alternating magnetic field in cancer cells’, PLoS ONE, 11(5), pp. 1–12. doi: 10.1371/journal.pone.0156294. Hoskins, C., Cuschieri, A. and Wang, L. (2012) ‘The cytotoxicity of polycationic iron oxide nanoparticles: Common endpoint assays and alternative approaches for improved understanding of cellular response mechanism’, Journal of Nanobiotechnology. BioMed Central Ltd, 10(1), p. 15. doi: 10.1186/1477-3155-10-15. Jayash, S. N. et al. (2016) ‘In vitro evaluation of osteoprotegerin in chitosan for potential bone defect applications ’, PeerJ, p. e2229. doi: 10.7717/peerj.2229. Journal, D. et al. (2012) ‘BIOGENIC SYNTHESIS OF Fe 3 O 4 NANOPARTICLES USING TRIDAX PROCUMBENS LEAF EXTRACT AND ITS ANTIBACTERIAL ACTIVITY’, Digest Journal of Nanomaterials and Biostructures Vol., 7(3), pp. 1655–1660. Kasner, E. et al. (2013) ‘Fundamentals and Application of Magnetic Particles in Cell Isolation and Enrichment’, pp. 646–656. doi: 10.1002/ana.22528.Toll-like. Kim, J., Hegde, M. and Jayaraman, A. (2010) ‘Co-culture of epithelial cells and bacteria for investigating host-pathogen interactions’, Lab on a Chip, 10(1), pp. 43–50. doi: 10.1039/b911367c. Kocaman, A. Y. and Topaktas, M. (2007) ‘In Vitro Evaluation of the Genotoxicity of Acetamiprid’, Environmental and Molecular Mutagenesis, 490(April), pp. 483–490. doi: 10.1002/em. Liakos, I., Grumezescu, A. M. and Holban, A. M. (2014) ‘Magnetite nanostructures as novel strategies for anti-infectious therapy’, Molecules, 19(8), pp. 12710–12726. doi: 10.3390/molecules190812710. López-Marín, L. M. et al. (2010) ‘Biocompatible Metal-Oxide Nanoparticles: Nanotechnology Improvement of Conventional Prosthetic Acrylic Resins’, Journal of Nanomaterials, 2011, pp. 1–8. doi: 10.1155/2011/941561. Maria Dhivya, S. et al. (2016) ‘A Comparative Study on the Biopolymer Functionalized Iron Oxide Nanocomposite for Antimicrobial Activity’, Materials Today: Proceedings. Elsevier Ltd, 3(10), pp. 3866–3871. doi: 10.1016/j.matpr.2016.11.042. Michalak, G. et al. (2016) ‘Magnetic nanoparticles as a drug delivery system that enhance fungicidal activity of polyene antibiotics’, Nanomedicine: Nanotechnology, Biology and Medicine, pp. 2395–2404. doi: 10.1016/j.nano.2016.07.006. Moreno-Vega, A. I. et al. (2012) ‘Polymeric and ceramic nanoparticles in biomedical applications’, Journal of Nanotechnology. doi: 10.1155/2012/936041. Niemirowicz, K. et al. (2016) ‘Magnetic nanoparticles as a drug delivery system that enhance fungicidal activity of polyene antibiotics’, Nanomedicine: Nanotechnology, Biology, and Medicine, 12(8), pp. 2395–2404. doi: 10.1016/j.nano.2016.07.006. Pham, T. et al. (2014) ‘Effect of PEG molecular weight on stability, T2 contrast, cytotoxicity, and cellular uptake of superparamagnetic iron oxide nanoparticles (SPIONs)’, Colloids and Surfaces B: Biointerfaces. Elsevier B.V., 119, pp. 106–114. doi: 10.1016/j.colsurfb.2014.04.027. Polakova, K. et al. (2015) ‘In vitro cytotoxicity analysis of doxorubicin-loaded/superparamagnetic iron oxide colloidal nanoassemblies on MCF7 and NIH3T3 cell lines’, International Journal of Nanomedicine, 10, pp. 949–961. doi: 10.2147/IJN.S72590. Priyadarsini, S., Mukherjee, S. and Mishra, M. (2018) ‘Nanoparticles used in dentistry: A review’, Journal of Oral Biology and Craniofacial Research. Craniofacial Research Foundation, 8(1), pp. 58– 67. doi: 10.1016/j.jobcr.2017.12.004. Ramimoghadam, D., Bagheri, S. and Hamid, S. B. A. (2014) ‘Progress in electrochemical synthesis of magnetic iron oxide nanoparticles’, Journal of Magnetism and Magnetic Materials. Elsevier, 368, pp. 207–229. doi: 10.1016/j.jmmm.2014.05.015. Rastegari, B. et al. (2017) ‘The enzyme-sensitive release of prodigiosin grafted β-cyclodextrin and chitosan magnetic nanoparticles as an anticancer drug delivery system: Synthesis, characterization and cytotoxicity studies’, Colloids and Surfaces B: Biointerfaces. Elsevier B.V., 158, pp. 589–601. doi: 10.1016/j.colsurfb.2017.07.044. Rio Clar, M. (2014) ‘Aplicación de nanopartículas magnéticas de hierro a la eliminación de mercurio del agua’, p. 31. Available at: http://dspace.uib.es/xmlui/bitstream/handle/11201/1143/TFG_QUIMICA_DelRioClarMateu.pdf? sequence=1. Sánchez-Sanhueza, G. (2016) ‘Antimicrobial Nanoparticles in Dentistry. A fad or a real therapeutic option?’, Journal of Oral Research, 5(4), pp. 140–141. doi: 10.17126/joralres.2016.030. Saxena, N. and Singh, M. (2017) ‘Efficient synthesis of superparamagnetic magnetite nanoparticles under air for biomedical applications’, Journal of Magnetism and Magnetic Materials. Elsevier B.V., 429(September 2016), pp. 166–176. doi: 10.1016/j.jmmm.2017.01.031. Silva, L. H. A. et al. (2016) ‘Labeling mesenchymal cells with DMSA-coated gold and iron oxide nanoparticles: Assessment of biocompatibility and potential applications’, Journal of Nanobiotechnology. BioMed Central, 14(1), pp. 1–15. doi: 10.1186/s12951-016-0213-x. Valdiglesias, V. et al. (2016) ‘Are iron oxide nanoparticles safe? Current knowledge and future perspectives’, Journal of Trace Elements in Medicine and Biology, 38, pp. 53–63. doi: 10.1016/j.jtemb.2016.03.017. Wideman, T. H., Zautra, A. J. and Edwards, R. R. (2014) ‘NIH Public Access’, 154(11), pp. 2262–2265. doi: 10.1016/j.pain.2013.06.005.Re-Thinking. Yan, Y. et al. (2018) ‘Development of Fe3O4–HA/PU superparamagnetic composite porous scaffolds for bone repair application’, Materials Letters. Elsevier B.V., 212, pp. 303–306. doi: 10.1016/j.matlet.2017.10.067. Yoneda, M. et al. (2013) ‘Effects of Fe3O4 Magnetic Nanoparticles on A549 Cells’, International Journal of Molecular Sciences, 14(8), pp. 15546–15560. doi: 10.3390/ijms140815546. Zamora-Mora, V. et al. (2017) ‘Chitosan nanoparticles for combined drug delivery and magnetic hyperthermia: From preparation to in vitro studies’, Carbohydrate Polymers. Elsevier Ltd., 157, pp. 361–370. doi: 10.1016/j.carbpol.2016.09.084. Zhong, S. et al. (2017) ‘Folic acid functionalized reduction-responsive magnetic chitosan nanocapsules for targeted delivery and triggered release of drugs’, Carbohydrate Polymers. Elsevier Ltd., 168, pp. 282–289. doi: 10.1016/j.carbpol.2017.03.083.
Acosta-Torres, L. S. et al. (2012) ‘Cytocompatible antifungal acrylic resin containing silver
nanoparticles for dentures’, International Journal of Nanomedicine, 7, pp. 4777–4786. doi: 10.2147/IJN.S32391. Adibkia, K. et al. (2014) ‘Antimicrobial activity of the metals and metal oxide nanoparticles’, Materials Science and Engineering: C, 44, pp. 278–284. doi: 10.1016/j.msec.2014.08.031. Agotegaray, M. A. et al. (2017) ‘Magnetic nanoparticles for drug targeting: From design to insights into systemic toxicity. Preclinical evaluation of hematological, vascular and neurobehavioral toxicology’, Biomaterials Science, pp. 772–783. doi: 10.1039/c6bm00954a. Arteche Pujana, M. et al. (2013) ‘Biodegradable chitosan nanogels crosslinked with genipin’, Carbohydrate Polymers. Elsevier Ltd., 94(2), pp. 836–842. doi: 10.1016/j.carbpol.2013.01.082. Asadi, Z. et al. (2017) ‘Investigation of the complex structure, comparative DNA-binding and DNA cleavage of two water-soluble mono-nuclear lanthanum(III) complexes and cytotoxic activity of chitosan-coated magnetic nanoparticles as drug delivery for the complexes’, Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. Elsevier B.V., 178, pp. 125–135. doi: 10.1016/j.saa.2017.01.037. Bae, J. E. et al. (2011) ‘The effect of static magnetic fields on the aggregation and cytotoxicity of magnetic nanoparticles’, Biomaterials. Elsevier Ltd, 32(35), pp. 9401–9414. doi: 10.1016/j.biomaterials.2011.08.075. Cao, M. et al. (2016) ‘Magnetic iron oxide nanoparticles accelerate osteogenic differentiation of mesenchymal stem cells via modulation of long noncoding RNA INZEB2’, Nano Research, pp. 626– 642. doi: 10.1007/s12274-016-1322-4. Coral, D. F. and Jenny A Mera, J. A. M. (2017) ‘Una Guía para el estudio de nanopartículas magnéticas de óxidos de hierro con aplicaciones biomédicas. Parte II’, Ingeniería y Ciencia, 13(26), pp. 207–232. doi: 10.17230/ingciencia.13.26.8. Costa, B. F. O. et al. (2016) ‘Development of a biocompatible magnetic nanofluid by incorporating SPIONs in Amazonian oils’, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 172, pp. 135–146. doi: 10.1016/j.saa.2016.04.022. Dobson, J., McBain, S. C. and Yiu, H. H. P. (2008) ‘Magnetic nanoparticles for gene and drug delivery’, International Journal of Nanomedicine, pp. 169–180. doi: 10.2147/IJN.S1608. Fatemi, M. et al. (2018) ‘Extracellular biosynthesis of magnetic iron oxide nanoparticles by Bacillus cereus strain HMH1: Characterization and in vitro cytotoxicity analysis on MCF-7 and 3T3 cell lines’, Journal of Biotechnology. Elsevier, 270(January), pp. 1–11. doi: 10.1016/j.jbiotec.2018.01.021. Gaharwar, U. S., Meena, R. and Rajamani, P. (2017) ‘Iron oxide nanoparticles induced cytotoxicity, oxidative stress and DNA damage in lymphocytes’, Journal of Applied Toxicology, pp. 1232–1244. doi: 10.1002/jat.3485. Gholoobi, A. et al. (2017) ‘Biopolymer-mediated synthesis of Fe3O4 nanoparticles and investigation of their in vitro cytotoxicity effects’, Journal of Molecular Structure. Elsevier B.V, 1141, pp. 594–599. doi: 10.1016/j.molstruc.2017.04.024. Gorobets, O., Gorobets, S. and Koralewski, M. (2017) ‘Physiological origin of biogenic magnetic nanoparticles in health and disease: From bacteria to humans’, International Journal of Nanomedicine, 12, pp. 4371–4395. doi: 10.2147/IJN.S130565. Gu, N. et al. (2016) ‘Response of MAPK pathway to iron oxide nanoparticles in vitro treatment promotes osteogenic differentiation of hBMSCs’, Biomaterials, pp. 11–20. doi: 10.1016/j.biomaterials.2016.02.004. Hapuarachchige, S. et al. (2016) ‘Non-temperature induced effects of magnetized iron oxide nanoparticles in alternating magnetic field in cancer cells’, PLoS ONE, 11(5), pp. 1–12. doi: 10.1371/journal.pone.0156294. Hoskins, C., Cuschieri, A. and Wang, L. (2012) ‘The cytotoxicity of polycationic iron oxide nanoparticles: Common endpoint assays and alternative approaches for improved understanding of cellular response mechanism’, Journal of Nanobiotechnology. BioMed Central Ltd, 10(1), p. 15. doi: 10.1186/1477-3155-10-15. Jayash, S. N. et al. (2016) ‘In vitro evaluation of osteoprotegerin in chitosan for potential bone defect applications ’, PeerJ, p. e2229. doi: 10.7717/peerj.2229. Journal, D. et al. (2012) ‘BIOGENIC SYNTHESIS OF Fe 3 O 4 NANOPARTICLES USING TRIDAX PROCUMBENS LEAF EXTRACT AND ITS ANTIBACTERIAL ACTIVITY’, Digest Journal of Nanomaterials and Biostructures Vol., 7(3), pp. 1655–1660. Kasner, E. et al. (2013) ‘Fundamentals and Application of Magnetic Particles in Cell Isolation and Enrichment’, pp. 646–656. doi: 10.1002/ana.22528.Toll-like. Kim, J., Hegde, M. and Jayaraman, A. (2010) ‘Co-culture of epithelial cells and bacteria for investigating host-pathogen interactions’, Lab on a Chip, 10(1), pp. 43–50. doi: 10.1039/b911367c. Kocaman, A. Y. and Topaktas, M. (2007) ‘In Vitro Evaluation of the Genotoxicity of Acetamiprid’, Environmental and Molecular Mutagenesis, 490(April), pp. 483–490. doi: 10.1002/em. Liakos, I., Grumezescu, A. M. and Holban, A. M. (2014) ‘Magnetite nanostructures as novel strategies for anti-infectious therapy’, Molecules, 19(8), pp. 12710–12726. doi: 10.3390/molecules190812710. López-Marín, L. M. et al. (2010) ‘Biocompatible Metal-Oxide Nanoparticles: Nanotechnology Improvement of Conventional Prosthetic Acrylic Resins’, Journal of Nanomaterials, 2011, pp. 1–8. doi: 10.1155/2011/941561. Maria Dhivya, S. et al. (2016) ‘A Comparative Study on the Biopolymer Functionalized Iron Oxide Nanocomposite for Antimicrobial Activity’, Materials Today: Proceedings. Elsevier Ltd, 3(10), pp. 3866–3871. doi: 10.1016/j.matpr.2016.11.042. Michalak, G. et al. (2016) ‘Magnetic nanoparticles as a drug delivery system that enhance fungicidal activity of polyene antibiotics’, Nanomedicine: Nanotechnology, Biology and Medicine, pp. 2395–2404. doi: 10.1016/j.nano.2016.07.006. Moreno-Vega, A. I. et al. (2012) ‘Polymeric and ceramic nanoparticles in biomedical applications’, Journal of Nanotechnology. doi: 10.1155/2012/936041. Niemirowicz, K. et al. (2016) ‘Magnetic nanoparticles as a drug delivery system that enhance fungicidal activity of polyene antibiotics’, Nanomedicine: Nanotechnology, Biology, and Medicine, 12(8), pp. 2395–2404. doi: 10.1016/j.nano.2016.07.006. Pham, T. et al. 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