Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
MAY, 2019
ii
ASSOSA, ETHIOPIA
ASSOSA UNIVERSITY
COLLEGE OF HEALTH
SCIENCES DEPARTMENT OF
MIDWIFERY
MAY, 2019
ASSOSA, ETHIOPIA
iii
Summary
Mental health problems in mothers can lead to increased maternal mortality and morbidity. Post
partum depression is one of the major global maternal mental health problem which leads to
greater maternal mortality rate related with suicide. Globally, about 10% and 13% of pregnant
women and who just gave birth respectively are suffering from mental health problems. Almost
all women are vulnerable for mental health problems during pregnancy and after childbirth in the
first year, but there are major factors which can lead a woman for postpartum depression. The
aim of this study is to assess the prevalence and associated factors of postpartum depression
among mothers attending post partum care in Asossa hospital, Assosa, Ethiopia, 2019. Facility
based cross-sectional study design will be used to collect data on the prevalence and associated
factors of postpartum depression in Assosa hospital , Assosa, Ethiopia from May to June, 2019.
Mothers who come for post natal care and vaccination within six month of delivery will be
included in the study and sampling will be done by consecutive sampling until the required
sample size 259 will be achieved. The proposed total budget to conduct this study will be
21083.00 ETB.
iv
Table of contents
1. Introduction ................................................................................................................................. 1
1.1Background ............................................................................................................................ 1
2. Objectives ................................................................................................................................ 6
3.3. Population............................................................................................................................. 7
4. Work plan.................................................................................................................................. 12
6. References ................................................................................................................................. 14
7. Annexes..................................................................................................................................... 16
vi
CI Confidence interval
PI Principal Investigator
1. Introduction
1.1 Background
Postpartum depression is the other category by which Onset can range from 24 hours following
delivery to 4 - 6 weeks or 6 -12 months postpartum. However, symptoms are generally seen
within the first month.12 Onset can be abrupt or gradual. Untreated postpartum depression may
last for 3 to 14 months. Symptoms of postpartum depression include: depressed mood,
tearfulness, mood swings, inability to enjoy activities that used to be of interest, sleep
disturbance, fatigue, difficulty concentrating, and altered appetite. However, postpartum
depression is a non-psychotic depression and only very rarely will a woman carry out harmful
thoughts (4-7).
Postpartum psychosis is a severe and rare disorder with an acute onset after a symptom free
phase. Most postpartum psychoses begin within the first 3 weeks after delivery. Its incidence is
0.1 – 0.2 %. Symptoms include delusions, hallucinations and gross impairment in functioning.
Affective symptoms are most prominent (3).
2
Mental health problems are a major public health issue for women of reproductive age (15–44
years) in both high and low-income countries. About 7% of the global burden of diseases among
women is contributed to mental health problems, especially among women of reproductive age
(8, 9). Post partum depression is one of the major global maternal mental health problem which
leads to greater maternal mortality rate related with suicide (10).
Globally, about 10% and 13% of pregnant women and who just gave birth respectively are
suffering from mental health problems .In developing countries it is more higher 15.5% through
pregnancy and 19.8% after child birth. Studies show that the prevalence of postpartum
depression is 9.2% in Sudan, 28.8% in Pakistan, 43% in Uganda, 31.7% in South Africa and
56% and 34% during pregnancy and after childbirth respectively in Jamaica. On the other hand
reports show that self reported postpartum depression in 17 U.S states ranged from 11.7% to
20.4% ,and 8.4% and 8.6% in Canada for minor and major mental disorders(10-13,18,19,20) .
Almost all women are vulnerable for mental health problems during pregnancy and after
childbirth in the first year, but there are major factors which can lead a woman for postpartum
depression (10). This include poverty(13), unintended pregnancy(3, 18),low social support(1,
4),low educational level(19-21), stress full life events and traumatic experience (8, 12),domestic
violence (12), previous psychiatric illness(1, 23) ,unemployment(21, 24) , poor husband
support(9) and losing a baby or having an infant who is hospitalized (16).
Postnatal depression affects 10-15% of mothers (10, 14, and 15). Untreated postnatal depression
is associated with impairment of the mother’s ability to care for her infant, marital instability,
impairment in the cognitive and emotional development of the child and increased utilization of
health care services. Yet most of these mothers are unrecognized, undiagnosed and therefore not
treated (15, 16). In severe cases mothers may commit suicide due to that children’s growth, mother-
infant attachment and breast feeding will be negatively affected. But treating this disorder helps to tackle
this troubles in addition it will help to reduce malnutrition and diarrhea of children’s (10).
3
Although prior studies provide valuable information, most were conducted in highly developed
countries and regions and there is little research examining the prevalence and determinants of
post partum depression in developing countries, such as Ethiopia. In addition, research on factors
that contribute to postpartum depression is still scarce in Ethiopia. These gaps in previous studies
of postpartum depression signal a need for research that can shed light on what percentage of
mothers during six week postpartum period will have depression and the multiple factors
associated with postpartum depression.
The postnatal period is well established as an increased time of risk for the development of
serious mood disorders. Which can range from transient “ blue” immediately following child
birth to an episode of major depression and even sever, incapacitating, psychotic depression. The
problem occurs in 10-15% of women’s after childbirth (2).
Prevalence rates of PPD vary widely from region to region, from race to race and among women
of the same cultural backgrounds (1, 2,). According to the WHO global review of literature 10-
15% of women in developed countries experienced non psychotic clinical depression in the year
after giving birth. Most of them experienced this health problem in the first five weeks of
postpartum period. The rate of postpartum depression was higher in developing countries in
which 15.6% of women developed during pregnancy and 19.8% after child birth (9).
According to the CDC report of 2012 the global estimation of post partum depression ranges
from 5%-25%, but the procedural discrepancy with the studies formulate the real prevalence rate
unclear (5). Considering the prevalence of PPD on continent basis in India ,Germen, Canada,
Greenland, brazil and Portugal had a prevalence of 23% , 6.1%, 8.46% (minor/major) and 8.69
%( major) and 8.6% ,7.2% and 17.6% respectively (10, 21,).
A study done in Lebanon on the prevalence and determinants of post partum depression among
post partum women’s show that, the overall prevalence of PPD was 21%(12). Similarly
according a study carried out in Pelotas, a city in the Southern region of Brazil, between October
4
and November 2000, on prevalence of postpartum depression and associated factors among post
natal mothers show that the prevalence of post partum depression was 19.1%(22). A recent study
carried out in Enugu Hospital, South East Nigeria, 2015 among mothers who attended
postpartum clinics from two teaching hospitals and three private hospitals on the prevalence of
postpartum depression confirmed that the prevalence was 22.9%(23).
A cross-sectional survey was conducted in two primary health care facilities in Mzuzu city,on
prevalence and determinants of depression among post partum mothers. The result of this study
confirmed that the prevalence of depression among post partum mothers were 12.4% (17). From
a study done in Uganda in a peri urban primary care centre, the Prevalence of major depression
at six weeks postpartum was 6.1%(24). In addition according to a study done in South Africa
Cape Town to determine the prevalence and correlates of mood disorders in pregnancy, found
that prevalence rate was 39%.The importance of this was that evaluation of antenatal depression
was important as it is a predictor of PPD(1). a prospective study on the socio demographic and
clinical features of PPD among Turkish women in 2008, PPD was responsible for about 15.4%
of all depressive mental disorders (25).
In sub Saharan countries the problem is also getting an attention for example in 2010-2011 a
community based study in prenatal screening for PPD was conducted in south Africa and related with
it the prevalence was known to be 31.7%(1),and according to a study which was conducted by the
year 2013-2014 in Sudan the prevalence was 9.2%(13) in other sub-Saharan countries like Uganda
the prevalence was as high as 43% (19) .
A community based study on the prevalence and associated factors of postpartum depression
among postpartum mothers in western zone benshangul point out that significant proportion of
mothers (19%) who gave birth in eastern benshangul demonstrated depression n during post
partum period (16).
Research suggests that women with various risk factors related to health and environment may
have a higher likelihood of developing a postpartum depressive disorder. It is generally believed
that risk factors can help identify women who may develop postpartum depression (2).
Consequently; these women may receive appropriate care during pregnancy or follow-up after
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delivery. Regarding factors associated with maternal postpartum depression, existing studies
have examined predictors from socio-demographic, psychological, and cultural perspectives.
Prior researchers have found that lower maternal education level and poor family economic
status were related to a higher prevalence of postpartum depression (26). Empirical literature has
consistently demonstrated that poor relationships with husbands or family members (i.e.,
relationships with mothers and/or mothers-in-law) are linked to a greater likelihood of women
experiencing postpartum depressive symptoms post- delivery (22). Furthermore, studies have
shown that a lack of psychological preparedness for pregnancy and insecure attachment styles to
partners (i.e., avoidance and anxiety) are associated with a higher risk of postpartum depression
(27). Moreover, there is a preference for giving birth to a boy in some Asian societies, and the
association between infant’s sex and postpartum depression has attracted scholars’ interest (22).
Several studies based in Asian contexts (e.g., India, Hong Kong, Vietnam) have shown that the
delivery of a baby girl led to a greater risk of postpartum depression among women compared to
the delivery of a baby boy (27). Other factors thought to put women at risk of depression in the
postpartum period include low social support, depression during pregnancy, preference of sex of
the baby, history of depression (12,22)
Early identifying maternal mental health problems and associated factors are potentially an
effective strategy for decreasing maternal mortality and morbidity related to mental health
problems. So early screening for postpartum depression would improve the ability to recognize
these disorders and hence necessitate enhanced care that ensures appropriate clinical outcomes.
Taking this into consideration, this study will be conduct to identify the prevalence of post
partum depression and its associated factors which will help in the design and implementation of
postnatal mental health assessment intervention in all child bearing women. The evidence from
this study will assist policy makers and program planners to take action to reduce morbidity and
mortality related with postpartum depression, So that they can take appropriate measure which is
suitable for our country. In addition to that the communities will gain a better insight about the
factors that may cause postpartum depression in postpartum women. Lastly it also helps other
researchers use this research’s findings as a stepping stone for additional research on the same
topic.
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2. Objectives
2.1. General objectives
To assess the prevalence and associated factors of postpartum depression among mothers
attending post partum care in Assosa hospital, assosa, Ethiopia, 2019.
To determine the prevalence of postpartum depression in Assosa hospital, Assosa, Ethiopia, 2019.
To identify factors associated with postpartum depression in Assosa hospital, assosa, Ethiopia,
2019.
7
The study will be conducted from May to jan 2019 Assosa hospital, Benshangul, Ethiopia.
Assosa is found at 676 Km weast of Addis Ababa with latitude and longitude 130
29’N39’E13.4830N39.4570E and at elevation of 2084 meters above sea level. It is Assosa 4
Kebeles which are named corner by corner. Assosa has 1 governmental hospitals, 1
governmental health centers all of them are giving delivery service, postnatal care according to
regional health bureau. Assosa hospital starts to give service in april, . currently it serves about
population in its catchment area of the Oromia, Amhara regional part of Ethiopia .
Institutional based cross-sectional study design will be used to collect data on the prevalence and
associated factors of postpartum depression in Assosa hospital, Assosa, Ethiopia from May to
June, 2019.
3.3. Population
3.3.1. Source population
The source populations were all women who came for postnatal care and vaccination services
within 6 weeks after delivery in Assosa hospital, Assosa, Ethiopia.
Each eligible women who came for postnatal care and vaccination service within 6 weeks after
delivery in Assosa hospital.
All women who came for postnatal care and vaccination service within 6 weeks after delivery in
Assosa hospital during data collection period and who are volunteer to participate in the study
and those who are within six weeks of delivery will be included.
8
Those mothers who are unable to respond due to different health problems, those mothers with
known mental problems who are on anti psychotic drugs and known psychiatric disorder will be
excluded from the study
The required sample size will be determined using single population proportion formula as
follows
N = (Z α/2)2 p (1-p)/ d2
N=Sample size.
Z=Standard error from the mean corresponding to 95% confidence level=1.96
P=19% taken from previous studies (16)
d = margin of error taken as 5%
Eligible participants will be approached and will request to consent voluntarily to participate into
the study. Upon consenting, a study number with a code will assigned for identification.
Inclusion into the study will be done by consecutive sampling until the required sample size 259
will be achieved.
Previous psychiatric history (history of depression and family history of psychiatric problems)
Postpartum period; it’s a period beginning immediately after the birth of a child and extending
for about six weeks.
Postpartum depression; women who experience depressed mood or sever mood swing,
excessive crying, difficult bonding with baby, withdrawing from family and friends, loss of
appetite or eating much more than usual, inability to sleep, overwhelming fatigue or loss of
energy.
Mental health; it’s a level of psychological well being or an absence of mental disorder it’s a
psychological state of someone who is functioning at satisfactory level of emotional and
behavioral adjustment
Social support; the perception and actuality that one is cared for, has assistance available from
other people
Socio-cultural; a set of belief, customs, practice and behavior that exist in a certain society.
A structured interviewer administered questioner will be used to collect information from study
participants. The instrument will be adopted from previous published literatures ( 1,8,10,) and
edited .The questioner will be designed in English and translated to local Amharic language and
then back translated in to English by the third person to cheek for consistency
10
The 10 questions of Edinburg postnatal depression scale (EPDS) is a valuable and efficient way
of identifying patients at risk for postnatal depression. It indicates how the mother has felt during
the previous 7 days. Data will be collected with an interviewer administered questionnaire to
gather information from mothers who come for postnatal and vaccination service. Data will be
cheeked for completeness every day and entered in to computer. Three nurses who graduated
diploma in nursing will be required as data collectors and they will be trained for one day on
information about the research objective, eligible study subjects, data collection tools and
procedures, and interview methods.
The data collection instrument will pretest for accuracy of responses, language clarity,
appropriateness of data collection tools, estimate the time required and the necessary amendments
will be considered based on it prior to the actual data collection. It will be carried out one week
proceeding to the actual data collection period in health center, in five percent of non study
participants that fulfill the inclusion criteria. In addition, the data collectors will be trained for one
day on the techniques of data collection. The training also included importance of disclosing the
possible benefit and purpose of the study to the study participants before the start of data collection.
Maintaining confidentiality of the participants throughout the whole process of data collection will be
discussed and ascertained during the training. The researcher will check for completeness and
consistency of questionnaires filled by the data collectors to ensure the quality of the data, and also
visit the data collectors as many times as possible to check whether he/she collect the data
appropriately. The researcher will also appraise the data during the data analysis stage to verify the
completeness of the collected data.
After data collection, filled data will be entered and analyses with IBM SPSS version 21 statistical
software and will subject to cleaning using simple frequency and tabulation to ensure its validity.
Ethical approval will be obtained from research ethical committee of assosa university department of
nursing. Written consent will obtained from Assosa hospital administrative office of medical
director. Permission will attained from the responsible body to hospital. Written informed consent
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will be obtained from each participant after the investigator had explained the nature, purpose and
procedure of the study. Participants will be completed the questioner in a separate room whenever
they asked for it. Anonymity and confidentiality of the data providers will be strictly maintained.
Participants will be assured that their participation is voluntarily, and they have every right to
withdraw or refuse to give information at any time in the study without any penalty. Participants who
will be identified with depressive symptoms will be linked with mental health clinics.
Primarily, the result of this study will be submitted to, assosa university department of midwifery and
defended as partial fulfillment of the requirements for the degreedegree in bsc midwifery. The
information will be disseminated to the respective bodies and the results will be published in national
and international journal and presented in annual scientific meeting and conferences
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4. Work plan
Table 1: work plan for a proposal project among mothers in assosa hospital, 2019
2009/2017
May June July august
Title selection and ASU Investigator
Development of
research proposal
Submitting ASU Investigator+AS
proposal and U+ECC
obtaining ethical
clearance from
MU ethical
clearance
committee
Production of data ASU Investigator
collection tools
Recruiting and ASSOS Investigator
training of data A
collectors
Field work data Data Investigator and
collection collectio data collectors
n site
Data entry, ASU Investigator
cleaning and
analysis
Report write up ASU Investigator
and presentation
Report submission ASU Investigator
Finding ASU Investigator
dissemination
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5. Budget break dow Table 2: budget break down for a proposal among mothers of post
partum depression in assosa hospital, 2019
6. References
1. Warfa, K. Prevalence of postpartum depression using the EPDS at the Aga Khan
University Hospital Nairobi. Unpublished MMED thesis AKUH 2011.
2. Burns, D. Aspects of Postpartum Depression. London, Ontario: Middlesex-London
Health Unit. 2003.
3. Boyce P. Personality dysfunction, marital problems and postnatal depression. In Cox J,
Holden J, eds. Perinatal Psychiatry: use and misuse of the Edinburgh Postnatal
Depression Scale. London. Gaskell. 1994.
4. Nonacs, R., & Cohen. Postpartum mood disorders: Diagnosis and treatment guidelines.
Journal of Clinical Psychiatry,1998: 59(2), 34-40
5. Epperson, C.N. Postpartum major depression: Detection and treatment. American Family
Physician.1999: 59, 2247-2254
6. Seidman, D. Postpartum psychiatric illness: The Role of the pediatrician. Pediatrics in
Review, 1998:19, 128-131
7. Jennings, K., Ross, S., Popper, S., & Elmore, M. Thoughts of harming infants in
depressed and nondepressed mothers. Journal of Affective Disorders,1999: 54, 21-28.
8. Giri et al. Prevalence and factors associated with depressive symptoms among post-
partum mothers. BMC Research Notes. (2015) 8:111
9. World Health Organization. Maternal Mental health and Child Health and Development
in Low and Middle Income Countries. Geneva: 2008.
10. Lanes et al. Prevalence and characteristics of Postpartum Depression symptomatology
among Canadian women: a cross-sectional study. BMC Public Health 2011, 11:302
11. 47. Martin O’Malley GAGB, Lieutenant Governor; John M. Colmers. Postpartum
Depression Among Maryland Women Giving Birth 2004-2008. Maryland Department of
Health and Mental Hygiene Center for Maternal and Child Health, Vital Statistics
Administration. January 2011:1-4.
12. Chaaya M. et al. Postpartum depression: prevalence and determinants. Arch Womens
Ment Health. 2002; 5(2): 65–72
13. Khalifa DS, Glavin K, Bjertness E, et al. Determinants of postnatal depression in
Sudanese women at 3 months postpartum: a cross-sectional study. BMJ Open 2016;6
14. Kumar R. Postnatal mental illness: Transcultural perspective. Social psychiatry
epidemiology ,1994: 29: 250-264….14
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7. Annexes
part in the study on the basis of my interest besides; I am briefed that I will be interviewed for
not more than 20 minutes. Moreover am notified that my participation in the study is entirely
volunteer, and that I can quite from the study any time I want. Likewise am enlighten that I will
not be subject to any form of punishment following my failure to participate in the study. In the
same way am explained that the information collected will not be disclosed by any means to any
people other than those participating in the study unless obtained permission from me. Equally,
am told that I can ask them question I found difficulty or any type otherwise.
Client signature/Thumb print ………………… Date……..
Annex 3
religious/cultural
rituals do you
follow?
105 Current marital a) Single
status? b) Married
c) Divorced/separated.
d) Widowed
106 Have you ever a) Yes If your response
attended school? b) No for no 106 is “B”
skip to no 108
107 Level of school you a) Primary school (1-8
attend b) Secondary school(9-12)
c) Technical/vocational
d) Diploma
e) First degree and above-
108 Occupational status a) Student If your response
b) paid worker for no 108 is “B”
c) unpaid employee go to no 109 but if
d) House wife without “B” skip
e) Merchant to no 110
f) Pensioner
g) Farmer
h) Unemployed
i) others-specify………..
109 If you are paid a) Civil servant
worker what is your b) non civil servant
occupational c) NGO employee
condition? d) daily laborer
e) house maid
f) Others-specify------------
110 Husbands a) Student
19
occupation b) Merchant
c) civil servant
d) non civil servant
e) Unemployed
f) day laborer
g) others specify ------------
111 Average monthly a. < 445 birr
income? b. 446-1200
c. 1201-2500
d. 2501-3500
e. >3501
f. I don’t know
g. I don’t have my own
income
112.1 Sex of your baby a. Male
b. female
112.2 sex for the last a. Desired
baby? b. Undesired
c. I don’t mind
Part II : factors associated with postpartum depression
201 Number of pregnancy
202 Number of living children do
you have?
203 Have you ever had an abortion? a) Yes
b) No
204 Number of abortion you
experienced?
205 Have you ever experienced a) Yes
death of your baby? b) No
206 Did any of your children are a) Yes
hospitalized? b) No
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c. more or less
d. Others-specify
219 Did any of your relatives present a. Yes
in health facilities during your b. No
last child birth?
306 In the past seven days things a) Yes, most of the time I
have been getting on top of you? haven’t been able to cope at
all
b) Yes, sometimes I haven’t
been coping as well as usual
c) No, most of the time I have
coped quite well
d) No, I have been coping as
well as ever
307 In the past seven days have you a) Yes, most of the time
been so unhappy that you have b) Yes, sometimes
had difficulty sleeping? c) Not very often
d) No, not at all
308 In the past seven days have you a) Yes, most of the
felt sad or miserable? b) Yes, quite often
c) Not very often
d) No, not at all
309 In the past seven days have you a) Yes, most of the time
been so unhappy that you have b) Yes, quite often
been crying? c) Only occasionally
d) No, never
310 In the past seven days did you a) Yes, quite often
have the thought of harming b) Sometimes
yourself? c) Hardly ever
d) Never