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RASHIDA IQBAL FINANCIAL AID

ORGANIZATION
PATHOLOGY GUIDELINES:

Gastrointestinal system
• Apthous ulcers,
• oral manifestations of systemic diseases,
• fibrous proliferative lesions (pyogenic granuloma ass with pregnancy),
• List (names) of benign and malignant tumors of oral cavity,
• pleomorhpic adenoma,
• mucoepidermoid carcinoma,
Risk factors for Oral squamous cell carcinoma,
• Morphology of squamous cell carcinoma.
• Atresia and Tracheo-esophageal fistula commonest type,
• Meckel’s di erticulum,
• Hirschprung’s disease,
• achalasia cardia,
• Barret’s esophagus,
• Adenocarcinoma of esophagus (esp microscopic diagnosis),
• GERD,
• peptic ulcers,
• Gastritis (esp differences H pylori and autoimmune).
• Adenocarcinoma of stomach differences between diffuse and infiltrative type of
adenocarcinoma,
• Enterocolitis (those organisms which were important in microbiology are likewise important
here),
• List of malabsorptive disorders,
• Polyps,
• Celiac disease,
• Carcinoid tumors and syndrome,
• Colorectal cancer (etiology, protective factors, association with FAP, exophytic presentation
of these, morhoplogy), Pathogenic pathways of Colorectal cancer.
• Hepatitis A,B,C,D,E (esp diagnosis graphs), Liver function tests, Biliary assessment (via CT,
ERCP, MRCP),
• Non Alcoholic steato-hepatitis (NASH), Alcoholic fatty liver disease, Non- Alcoholic fatty liver
disease,
• Metabolic liver disorders,
• Hepatocellular carcinoma (esp risk factors are very important, small cell change, large cell
change), alpha feto protein as a indicator of Hepato-cellular carcinoma,
• Gall stones,
• Acute pancreatitis (causes: alcohol and biliary obstruction & pathogenesis),
• Complications of acute and chronic pancreatitis, Pancreatic cancer (Pathogenesis i.e. genes
& clinical presentations)

Blood Vessels and Heart


• Atherosclerotic plaque,its microscopic features and complications
• Kaposi sarcoma
• mechanisms involved in non infectious vasculitis,giant cell arteritis
• Atheroma formation(role of monocytes)
• Atherosclerosis:principal components,morphology,complications
• Major and minor risk factors for atherosclerosis
• Role of hyperlipidemia in atherosclerosis
• Classification aneurysms
• Clinical course,aetiology and morphology of aneurysms
• Types of hypertension
• Infective endocarditis,morphological lesions
• Myocardial infarction(morphological changes and comlications)
• Limbman-Sacks endocarditis
• Complications of bacterial endocarditis
• Lab evaluation oF MI (Table on page 380 med robbins)
• Pathogenesis of Rheumatic heart disease
• Lab diagnosis & comlications of RHD
• Heart failure cells def
• Cor-pulmonale
• Morphological feature of Right sided heart failure
• Causes of sudden cardiac death
• Sequence of events in heart failure (schemetic represention,big robbins)
• Changes in infarcts with age of injury

CENTRAL NERVOUS SYSTEM


Note There Is No need To Do Full Chapter. Just Do the Following topics

• Meningitis. Morphology of Bacterial Meningitis( UHS 2017 Q)


• Alzheimer disease
• Parkinson disease
• Ischemia and Infarct
• Multiple sclerosis (Pathoma)
• Tumors are Very important. Usually question Is from Tumors
• Gliomas( Types of glial tumors, Grading and morphology of each grade)
• Neuronal tumors
• Medulloblastoma (drop metsastasis uhs Mcq)
• Classification Of tumors Is V Important

Musculoskeletal System
• Osteogenesis Imperfecta
• Achondroplasia
• Osteomyelitis (Acute and Chronic)
• Classification Of Bone tumors V imp
• Osteoma (MCQ 2017)
• Osteoid osteoma
• Osteosarcoma (do remember the percentage of occurence like 60%in knee... Four
histological subtypes.)
• Chondrosarcoma
• Ewing sarcoma V Imp
• Giant Cell Tumor
• Paget disease Morphology
• Osteoarthritis(pathoma)
• Rheumatoid arthritis
• Gout
• Classification Of soft tissue tumors
• Lipoma and liposarcoma(For Mcqs)
• Rhabdomyosarcom(variants)
• Leiomyosarcoma

Skin
Read Only pathoma For This

FGT
• Grading Of cervical cancer
• Pathology of cervical cancer,Types of cervical cancer
• Grading of endometrial cancer
• Endometriosis (Three hypothesis)
• Causes Of abnormal uterine bleeding(sendup question)
• Leiomyoma(morphology)
• Polycystic ovarian disease
• Tumors of ovary classification
• Gestational trophoblastics disease
• Eclampsia (Uhs Q 2017)
Breast (Do Breast From Big Robbins Get the chapter photocopied from There. Plus Must Do
Ahmad Bhai notes Of It)

A Seq always always comes from this topic. Cannot skip anything From this topic)

• Fibroadenoma (Uhs seq)

Haematology
• Classification Of anemia
• Sickle cell disease
• Thalassemia( Do Fig 11.6)
• Fe Def anemia
• Megaloblastic anemia
• Infectious mononuclesosis
• Who classification of lymphoid neoplasm
• ALL
• CLL
• Burkitt lymphoma
• Multiple myeloma
• Hodgkin lypmhoma v imp ,Staging of hodgkin lymphoma
• Difference between hodgkin and non hodgkin lypmhoma(Uhs seq 2017)
• AML
• CML
• DIC (do fig 11.28 only)
• HUS and TTP
• Causes of thrombocytopenia
• Causes of splenomegaly

ENDOCRINE SYSTEM
1 Seq Comes In Proff From This Chapter

• Table 19.1
• Prolactinoma
• Thyroid Is Very Important.
• Hashimoto thyroiditis pathogenesis. Proff ques.
• De quervain thyroiditis
• Graves Disease morphology
• Papillary carcinoma morphology v imp
• Difference between follicular carcinoma and adenoma
• Causes Of hypercalcemia
• table 19.4
• AGES formation test ques.
• Pathogenesis Of diabetes mellitus test ques
• Diabetic nephropathy
• DKA. Proff ques Need to memorize only table 19.33
• Pheochromocytoma. Send Up ques.
• Men1 and Men2

CVS
• 1 Seq Comes From Both Chapters In Proff.
• Atherosclerosis:Pathogenesis. Factors. Morphology
• Causes Of Hypertension
• Tumors Classification table 9.4.
• Kaposi sarcoma.
• Cavernous hemangioma Morphology.
• Test ques.
• Vasculitis. Classification.
• Role Of Anca
• Giant Cell arteritis
• PAN
• Wegner granulomatosis
• MI pathogenesis Table 10.3 is V Imp.
• Rheumatic Valvular disease
• Infective endocarditis
• Pericarditis morphology
• SCD causes

RESPIRATION
• Table 12.1 acute lung injury
• ARDS Pathogenesis. Fig 12.3
• Types of emphysema.
• Fig 12.7 V imp. It Includes pathogenesis of emphysema.
• Morphology Of emphysema Proff ques.
• Chronic Bronchitis
• Asthma morphology
• Table 12.3 Categories of interstitial lung disease
• Fig 12.14
• Silicosis morphology
• Asbestosis pathogenesis
• Causes Of Pulmonary Hypertension
• Table 12.6 Pneumonia syndromes
• Morphology pneumonia Proff ques V Imp.
• Lung abscess
• Do Only Fig 12.35 For pathogenesis
• Difference between Ghon complex and focus
• Lung tumor classification
• ASBESTOS INC 55 TIMES RISK for CA. Proff mcq.
• Morphology Of lung CA Imp.
• Azopardi effect.
• Table 12.8 comparison Of Sclc and nsclc
• Carcinoid tumor.
• Mesothelioma V Imp.

RENAL PATHOLOGY
• Poststreptococcal glomerulonephritis (morphology , pathogenesis, etiology),
• Classify renal tumors,
• Causes of hematuria,
• Causes of painless hematuria,
• Transition cell carcinoma(morphology, grading,risk factors),
• Diabetic nephropathy,
• Staging of tumors,
• IgA nephropathy,
• Nephritic syndrome,
• minimal change disease,
• Nephrotic syndrome,
• Acute pyelonephritis (diagram of steps of pathogenesis),
• Causes of acute tubular necrosis,
• Membranous nephropathy ,
• Causes of secondary glomerular disease,
• Hydronephrosis,
• Polycystic kidney disease,
• Rapidly progressive glomerulonephritis.

TOPICS YOU CANT AFFORD TO MISS IN 3RD PROFESSIONAL EXAMINATION

BY DR EJAZ WARIS, ASSOCIATE PROFESSOR HISTOPATHOLOGY , AMDC

1. CVS

Atherosclerosis (pathogenesis, predisposing factors, morphology)

Myocardial Infarction (chart of changes, morphology)

Myocarditis (causes, morphology)

Tumors of Blood Vessels (Classification and details of hemangioma, kaposi sarcoma and
angiosarcoma)

hypertensive heart disease

Cardiac tumors (names, Myxoma)

Vasculitis (classification, role of ANCA, giant cell arteritis, PAN, wegener granulomatosis)
Definition and classification of cardiomyopathy

Rheumatic heart disease & infective endocarditis

Cardiac failure

2. LUNG

Emphysema (definition, classification, pathogenesis)

Bronchiectasis

Lung abscess

Salient features of asthma and chronic bronchitis (according to pathogenesis, morphology)

Classification of pneumonia (details of pneumonia in immunocompromised)

Bronchogenic carcinoma (esp. Small cell, squamous cell carcinoma)

mesothelioma (how it differs from adenocarcinoma)

3. HEAD & NECK

Nasopharyngeal carcinoma

Paraganglioma

Salivary gland tumors (pleomorphic adenoma, adenoid cystic carcinoma, warthin's tumor,
mucoepidermoid carcinoma)

Thymoma

4. GIT

Esophagus (Barrets and reflux)

Stomach (role of H.pylori in ulcer and chronic gastritis, 4 associated lesions and Carcinoma of
stomach in complete)

Intestine (diff between crohn disease & ulcerative colitis, coeliac disease, polyps-neoplastic & non
neoplastic-,Carcinoma colon,causes of malabsorption-diarrhea / table of robbins)

Appendix (carcinoid , acute appendicitis )

5. LIVER & PANCREAS


Hepatitis ( A, B, C )

Chronic hepatitis – basic features + knodell scoring system

Cirrhosis (causes,morphology, types-alcoholic and primary billiary-)

Tumors (names, hepatocellular carcinoma)

Chronic cholecystitis

Gall stones

Chronic pancreatitis

Acute hemorrhagic pancreatitis (pathogenesis , causes)

Carcinoma of pancreas ( genetics , morphology )

6. KIDNEY

Renal cell carcinoma

Diabetic kidney

SLE

Glomerulonephritis (types, pathogenesis ,details of acute post streptococcal, minimal change


,membranous,membranoproliferative and rapidly progressive)

Chronic pyelonephritis/causes of hydronephrosis – table /kidney stones

7. BLADDER

transitional cell carcinoma – staging , WHO grading with features , etiology

malakoplakia – what is it?

list of types of cystitis

8. MALE GENITAL SYSTEM

Testicular tumors (classification and its importance, seminoma, yolk sac, embryonal)

BPH (pathogenesis, morphology)

CA prostate (with gleaseon grading system)


9. FEMALE GENITAL SYSTEM

Cervix (carcinoma, role of HPV, morphology, staging, CIN-Bethesda)

Uterus (endometrial hyperplasia, carcinoma of endometrium, diagnostic features of leiomyoma and


leiomyosarcoma)

Ovarian tumors (names and details of serous, mucinous, brenner, teratoma, granulosa cell tumor,
hydatidiform mole)

10. BREAST

CA breast classification + main to be done (ductal, lobular, medullary) + bloom grading

Prognostic factors (major and minor)

DCIS

List of premalignant lesions of breast

ER – PR / HER/2neu

List of proliferative lesions of breast , fibrocystic disease

11. ENDOCRINOLOGY

Thyroiditis (hashimoto, riedel,Dequirvan)

Multinodular goitre / graves

Carcinoma of thyroid (papillary, follicular, medullary)

Follicular adenoma

Pituitary adenoma – short note

Addison and cushing – brief idea with lab diagnosis

12. CNS

Meningitis

Tumors (astrocytoma, meningioma, oligodendroglioma,ependymoma, medulloblastoma,


schwannoma)

Brain injury / contusions


13. Diabetes

Pathophysiology of diabetic coma + lab diagnosis

Effects on kidney

14. BONES & JOINTS & SOFT TISSUE

Osteomylitis

Paget bone

Tumors classification + main types (osteosarcoma, chondrosarcoma, giant cell tumor, ewings tumor)

Rheumatoid (pathogenesis)

Gout (pathogenesis, role of HGPRT)

Soft tissue tumors (liposarcoma, fibrosarcoma, rhabdosarcoma, synovial sarcoma)

15. SKIN oNLY for mcqs.

Squamous cell carcinoma

Rodent ulcer/basal cell carcinoma

Malignant melanoma

Naevus

16. EYE

Retinoblastoma

17. NERVE & MUSCLE

Muscle dystrophy (names, duchenne)

18.HAEMATOLOGY

Hodgkin’s Disease

Classification of NHL ( Follicular,Burkitt’s and SLL)

CML,AML,ALL – lab diagnosis and genetic derangements

FAB classification

Multiple Myeloma – Pathogenesis , morphology

Anemia ( Iron deficiency,Megaloblastic,aplastic)

Thalessemia
DIC

Thrombocytopenia – types,causes

Note : All syllabus is important but these topics u cannot afford to miss – all the best☺

Mnemonics by Ahmad Hassan bhai :


https://web.facebook.com/ahmad.hassan.7161/media_set?set=a.10203863073817658&typ
e=3
Flash points by Dr. Ejaz waris for MCQs:
https://drive.google.com/file/d/1qQg29ocZLWleMGtoT9LK6nnYWHMV6Lnw/view?usp=sha
ring
WBC pathology notes :
https://drive.google.com/file/d/1i8oNeQsswK_FbHEutyu69fiyKFmEWOxH/view?usp=sharin
g
Pathology past papers :
https://drive.google.com/drive/folders/15JU9ngVJRjZH6Wr_pkCC_-
1mUWmJjx56?usp=sharing

CREDITS :
Mujtaba Haider (Publications Head)
Hira Anum (Publications Incharge)

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