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Postgraduate Program of Physiotherapy, Federal University of São Carlos, São Carlos, Brazil
Aim: To compare the effects of 16-week multicomponent and resistance training, and 6-week detraining on
physical variables related to a higher risk of falls in very old people.
Methods: A randomized, three-arm, controlled trial was carried out. A total of 69 community-dwelling older adults
aged 80 years and older were allocated to three groups: control, multicomponent training and resistance training.
They were assessed at baseline, after 16-week training and 6-week detraining. The control group did not perform any
intervention. The multicomponent group performed protocol consisting of warm-up, aerobic, strength, balance and
cool-down exercises. The resistance group underwent strength exercises using six adapted machines. The training
sessions had progressive intensity, lasted 16 weeks and 12 included three 1-h sessions per week. The assessment
consisted of anamneses, five-repetition sit-to-stand, one-leg standing, tandem and dual task tests. For statistical
analysis, α = 0.05 was used.
Results: There were no significant differences between groups and assessments in any variable when analyzed by
intention to treat. However, when analyzed, the older adults who adhered to the training, the multicomponent group,
had a significant improvement in the sit-to-stand and the one-leg standing (right support) tests. There was a
significant main effect between times on the one-leg standing (left support) test.
Conclusion: In very old people, multicomponent training seems to be more beneficial and presents fewer adverse
events when the adherence to protocol is higher. Geriatr Gerontol Int 2016; 16: 492–499.
Keywords: exercise, falls, oldest old, postural balance, randomized controlled trial.
Although studies report that physical exercise helps sealed envelope, which contained a card stating which
mitigate the physiological effects of aging, there is insuf- group the volunteer would be allocated to. The enve-
ficient evidence on which protocols are recommended lopes were opened after the first evaluation.
more for factors related to falls in those aged over
80 years.9–11 The purpose of the present study was to
Interventions
compare the effects of 16-week multicomponent and
resistance training programs on physical variables The CO group did not carry out any intervention. The
related to a higher risk of falls, and the fall rate in MT and RT groups underwent a 1-week familiarization
community-dwelling oldest-old people. Furthermore, period. The training lasted 16 weeks and included three
the same variables were analyzed after 6 weeks of 1-h sessions per week on non-consecutive days. The
detraining. It was hypothesized that there would be same researcher who carried out the assessment moni-
improvements for both training programs after the tored the interventions with help from trained physical
intervention, but with higher benefits for the multicom- educators.
ponent training. After detraining, a trend in worsening After the intervention period, the participants under-
performance in both intervention groups would be went a 6-week detraining period. There was no guid-
expected. ance during the detraining phase.
12th repetition of the third set.15 The upper and lower to carry out a comparative analysis. The MANOVA test was
limbs exercises were interspersed during training. used to verify interaction and differences between groups
and assessments. If a significant interaction was identi-
fied, analyses of simple main effects by group and
Measures
post-hoc (Tukey test) tests were carried out.
The volunteers were assessed at baseline, after training Because of the low adherence to training sessions, in
and after detraining. Descriptive variables were assessed addition to the analysis by intention to treat, differences
using a questionnaire at baseline and the volunteers were analyzed at baseline among the CO group and
were asked about falls in the past 3 months.16 people who adhered (attended at least 24 sessions for
16 weeks) or not to training sessions using one-way
ANOVA and χ2-tests. The MANOVA test was used to verify
Physical performance outcomes
the interaction and differences between the participants
Muscle strength of the lower limbs was assessed who adhered in the MT, RT and CO groups, and the
through the five-repetition sit-to-stand test, and the assessments.
time spent was noted (in seconds).17
The one-leg standing and tandem tests were used to
assess balance. In both tests, the participants were Results
instructed to keep their eyes opened, have bare feet,
keep their arms alongside their body and stare at a After 16 weeks from the baseline, all volunteers were
reference point 1 m away. The one-leg standing and the re-evaluated, except one individual from the MT group
tandem tests were carried out as described by who refused to participate. After the detraining phase,
Michikawa et al.18 and El-Sobkey,19 respectively. three elderly individuals from the CO group did not
The dual task was assessed using the Timed Up and carry out the assessment (one because of failure to
Go test (TUGT) at a normal pace while carrying a full contact and two because of refusal; Fig. 1).
cup of water (TUGT-motor), as described by Hofheinz Table 1 shows the major sociodemographic charac-
and Schusterschitz.20 A total of 10 volunteers used a teristics of the sample. There were no differences
cane to walk, and the test was carried out with a cane. A between groups for the sociodemographic characteris-
pretest was carried out for familiarization with a 1-min tics, except for the percentage of osteoarthritis, which
interval between attempts. was higher in the MT group and lower in the CO group.
All volunteers were independent in basic activities of
daily living. Among participants who reported falls in
Fall outcomes the previous 3 months, there was no difference between
After baseline assessment, the volunteers received a fall groups regarding the number, location or consequences
calendar, which should be completed until the end of of falls (52% reported any consequences). There was an
the study. Once a month, they were asked about falls by average of 1.1 falls.
phone or during days of training.
Adherence to treatment
Statistical analysis
Overall, 34.7% of the MT group and 56.5% of the RT
The sample size was calculated using G*Power 3.1 soft- group carried out at least 24 sessions for 16 weeks (half
ware (Universität Düsseldorf, Düsseldorf, Germany). of the intervention). The reasons for not participating or
Assuming the type of study design (MANOVA), type I participating in less than one-quarter of the sessions for
error at 5%, statistical power at 80% and an effect size of the MT group were transportation problems (n = 3),
0.4, a minimum of 66 participants should constitute the personal health problems (n = 6), spouse health (n = 4)
total sample. and refusal to participate (n = 1). Possible adverse effects
For analysis, a significance level of α = 0.05 was used, were mild muscle pain (n = 4), mild hematoma (n = 1)
and SPSS software was used (version 17.0; SPSS, and dizziness (n = 1). The reasons for participating in
Chicago, IL, USA) to run the tests. The analysis was less than one-quarter of the sessions for the RT group
carried out by intention to treat. Rejecting the normality were personal health problems (n = 3) and refusal to
hypothesis, the z-score calculation was used to standard- participate (n = 2). Possible adverse effects were mild
ize quantitative data. Descriptive analysis was carried out muscle pain (n = 9).
using the χ2-test of association and the one-way ANOVA. At baseline, the participants who adhered in the MT
The χ2-test of association was used to verify differences group carried out the sit-to-stand test significantly
in the frequency of fallers between groups and between slower (mean = 25.1 s [3.9 s]) than the participants who
the first two assessments. Because of the low frequency of adhered in the RT group, those who did not adhere
loss of water in the TUGT-motor test, it was not possible in the MT group and those in the CO group. The
Excluded (n=501)
Not being sedentary (n=26)
Health problems/Problemas de saude/unable to
walk alone (n=145)
Low MMSE score (n=6)
Difficulty in transport/long distance (n=109)
Unavailability related to spouse health (n=14)
Refusal to participate for other reasons (n=201)
Randomized (n=69)
Detraining (6 weeks)
Figure 1 Participants’ flowchart. CO, control group; MMSE, Mini-Mental State Examination; MT, multicomponent training
group; RT, resistance training Group.
DT (n = 20)
18.7 (11.9)
2 (10.0)
6 weeks of
15.5 (6.3)
5.5 (5.9)
7.0 (7.7)
25.3 (9.3)
24.7 (6.9)
who adhered (75%) than for those who did not (69%) in
5 (25)
the MT group, and lower for the CO group (17.4%).
Other baseline variables did not differ between the
subgroups.
17.6 (12.3)
28.0 (15.2)
8 (34.8)
16.4 (5.4)
4.9 (8.0)
5.5 (7.1)
25.8 (7.0)
2 (8.7)
16 weeks
Physical performance outcomes
Data presented as mean (standard deviation). P > 0.05 for all analyses between groups and assessments. DT, detraining; TUGT, Timed Up and Go Test.
(n = 23)
Five elderly participants from the CO group, two from
the MT group and one from the RT group were not
Control group
entered into the analysis of the sit-to-stand performance
16.5 (11.6)
8 (34.8)
(four older adults did not participate in any assessment
16.0 (4.7)
5.1 (6.5)
5.4 (6.0)
25.3 (8.4)
24.9 (5.1)
1 (4.3)
Baseline
and four older adults failed to carry out the test).
(n = 23)
Table 2 shows the performance of groups at each
assessment on the physical tests. There was no signifi-
cant interaction between group and assessment for any
variable. There was no significant main effect for groups
DT (n = 23)
18.2 (12.8)
26.7 (22.2)
26.9 (14.0)
6 weeks of
15.0 (7.3)
6.7 (7.4)
7.9 (8.1)
1 (4.3)
1 (4.3)
or assessments by intention to treat. Although the MT
group presented a growing improvement in the one-leg
standing test (right support), this change was not statis-
tically significant.
When analyzing the older adults who adhered to the
20.6 (12.2)
28.1 (15.3)
27.6 (13.4)
8 (34.8)
interventions, there was a significant interaction
16.2 (6.4)
7.0 (7.0)
7.4 (7.1)
16 weeks
(n = 23)
0 (0)
between groups and assessments in the sit-to-stand
(F = 5.316, P = 0.001) and the one-leg standing (right
Resistance group
18.3 (11.6)
29.0 (15.5)
27.7 (12.1)
7 (30.4)
the one-leg standing (right support) tests between the
18.1 (8.8)
6.0 (6.7)
6.6 (7.7)
2 (8.7)
Baseline
(n = 23)
11.1 (11.7)
10.7 (11.0)
19.8 (13.1)
29.8 (13.1)
6 weeks of
16.1 (5.1)
27.2 (9.7)
1 (4.5)
2 (9.1)
Fall outcomes
The volunteers were instructed to deliver the fall calen-
dar at the third assessment. However, 25 volunteers did
not deliver the calendar and four calendars were not
10.9 (11.8)
10.3 (11.2)
17.9 (12.7)
31.1 (22.8)
4 (18.2)
15.8 (7.7)
27.0 (9.2)
(n = 22)
0 (0)
17.3 (12.9)
30.4 (12.2)
10 (43.5)
26.4 (7.2)
Baseline
(n = 23)
0 (0)
support), s (0–30)
One-leg standing (left
TUGT-motor
No. steps
Discussion
Time, s
P-value
<0.001
<0.001
>0.05
>0.05
>0.05
>0.05
falls in community-dwelling people aged over 80 years.
Furthermore, the same variables were analyzed after a
6-week detraining period. In the analysis by intention to
treat, no significant differences between groups and
Groups of adherence to resistance training (n = 13), multicomponent training (n = 8) and control (n = 20) groups. †Analysis between resistance training (n = 12),
F2.35 value
–
–
tests between the first and second assessments, as well
as between the first and the third assessments. There
Multicomponent group –
3.6 (−4.1–11.4)
5.3 (−5.5–16.3)
4.3 (−3.4–12.0)
control group
1.2 (−5.8–8.4)
1.8 (−8.0–11.7)
−2.0 (−11.4–7.2)
3.5 (−2.5–9.6)
−1.9 (−8.5–4.6)
control group
0.7 (−11.6–13.2)
used.
Serra-Rexach et al. studied the effects of 8-week train-
Tandem, s (0–30)
Sit-to-stand (s)†
Figure 2 Strength and balance performance outcomes between adherence groups. *P < 0.05, **P < 0.01.
the TUG and sit-to-stand tests in the elderly individuals of the diversity of the older adults aged over 80 years,
aged over 80 years who underwent 8-week resistance difference in sit-to-stand performance between the sub-
training.28 Intensity and duration of training as well as groups of adherence, and poor adherence to the fall
the previous physical condition of people who under- calendar and training, especially in the MT group. The
went training could be decisive for outcomes after RT group used the same space as the younger elderly
detraining. participants who practiced physical exercise, had more
We did not identify any significant change in the social contact and a better view of the benefits of physi-
frequency of falls, but there was a clinically relevant cal activity, which could have influenced the difference
decrease after the MT training. Gillespie et al. suggested in the adherence between the groups. Literature involv-
multicomponent exercise protocols and home safety ing only older adults aged over 80 years and analyzing
interventions to reduce the rate of falls.7 People aged data by intention to treat is limited, which makes com-
over 80 years could require a combination of interven- parison of the results difficult. Nevertheless, the authors
tions to reduce the incidence of falls, because this event used tests with less risk of adverse events that were more
is multifactorial. Still, they suggested that falls should be functional and focused on clinical practice. This study
recorded daily and monitored monthly. Hannan et al.29 presented new information about the effects of physical
and Fleming et al.30 suggested the calendar was the pre- activity and a detraining phase in elderly individuals
ferred method for screening falls. However, the present aged over 80 years on variables related to a higher risk of
study did not have good adherence to the calendar, falls.
perhaps because of differences in the methods of No significant differences between training and
screening and the sample’s level of education. assessments were found in any variable related to the
This study presents some limitations, such as lack of risk of falls. However, multicomponent training seems
blinding, high standard deviations of variables because to be more beneficial and present fewer adverse events
when the adherence to protocol is higher. There is a 14 Carvalho MJ, Marques E, Mota J. Training and detraining
need for new approaches regarding dosages and com- effects on functional fitness after a multicomponent train-
ing in older women. Gerontology 2009; 55: 41–48.
ponents of interventions as well as new studies to deter-
15 Benson C, Docherty D, Bradenburg J. Acute neuromuscu-
mine how long the benefits of exercise can be lar responses to resistance training performed at different
maintained in older adults aged over 80 years. loads. J Sci Med Sport 2006; 9: 135–142.
16 Chiu AY, Au-Yeung SS, Lo SK. A comparison of four
functional tests in discriminating fallers from non-fallers in
Disclosure statement older people. Disabil Rehabil 2003; 25: 45–50.
17 Nakano M. Versão brasileira da Short Physical Perfor-
No potential conflicts of interest were disclosed. mance Battery-SPPB: adaptação cultural e estudo da
confiabilidade. 2007. 181f. Dissertation (Master in Physio-
therapy) – Universidade Estadual de Campinas, Faculdade
de Educação, Campinas-SP, 2007.
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