MCQs – Inflammatory Bowel Disease

Kathryn Clark

1. Inflammatory bowel disease: pg 807

a. Is an acute autoimmune condition
b. Includes ulcerative colitis and Crohn’s disease
c. Is more common in men
d. Frequently presents in the 5th decade.

2. Features of Crohn disease: pg 808

a. Transmural inflammation
b. Diffuse distribution
c. No granulomas
d. Associated with toxic megacolon

3. Features of ulcerative colitis: pg 808

a. Transmural inflammation
b. Skip lesions
c. Marked pseudo polyps
d. Mouth to anus distribution

4. The following is NOT thought to be involved in the pathogenesis of IBD: pg

807-809
a. Genetics
b. Mucosal immune responses
c. Epithelia defects
d. Abnormal GI motility

5. The extra-intestinal symptoms of both ulcerative colitis and Crohn’s disease

may include all EXCEPT: pg 810-811
a. Migratory polyarthritis
b. Ankylosing spondylitis
c. Uveitis
d. Erythema multiforme

6. Morphological features of Crohn disease include: pg 810-11

a. Skip lesions
b. Left-sided disease
c. Broad-based ulcers
d. pseudopolyps

7. Morphological features of ulcerative colitis include: pg 810-11

a. Skip lesions
b. Cobblestone appearance of mucosa
c. No granulomas
d. Noncaseating granulomas

8. Triggers of Crohn disease include all except: pg 811-12

a. Stress
b. Smoking
c. Dietary
d. Infectious enteritis

9. Initial presentation of Crohn disease: pg 811

a. May be a medical/surgical emergency
b. Begins with intermittent attacks of relatively mild diarrhoea
c. 20% present acutely with left lower quadrant pain
d. Never have bloody diarrhoea

10. Complications of ulcerative colitis include all EXCEPT: pg 812-13

a. Fistulae
b. Neoplasia
c. Primary sclerosing cholangitis
d. Toxic megacolon

Answers
1. b
2. a
3. c
4. d
5. d
6. a
7. c
8. d
9. b
10. a