O CH2-COOˉ

O=C-COOˉ + C-CH3 + H2O HO-C-COOˉ + HS-CoA + Hᶧ

H2C-COOˉ S-CoA CH2-COOˉ

COOˉ COOˉ COOˉ

H-C-H H2O
H-C H O
2
H-C-OH
ˉOOC-C-OH ˉOOC-C ˉOOC-C-H
CH2 CH2 CH2
COOˉ COOˉ COOˉ

Isocitrato + NAD+ α-cetoglutarato + CO2 + NADH

 COOˉ COOˉ COOˉ
CH2 NAD +
NADH +H CH2 H+ CO2 CH2
H-C-COOˉ H-C-COOˉ H-C-H
HO-C-H C=O C=O
COOˉ COOˉ COOˉ

α-cetoglutarato + NAD+ + CoA succinil-CoA + CO2 + NADH

Succinil-CoA + Pi + GDP succinato + GTP + CoA

GTP + ADP GDP + ATP

COOˉ COOˉ COOˉ COOˉ
CH2 FAD FADH2
C-H H2O
HO-C-H NAD +
NADH
C=O
+ H+

CH2 H-C H-C-H CH2

COOˉ COOˉ COOˉ COOˉ

E-FAD + succinato E-FADH2 + Fumarato

Malato + NAD+ oxalacetato + NADH + H+

Piruvato + CoA + NAD+ acetil-CoA + CO2 + NADH

Piruvato + TPP hidroxietil-TPP + CO2

 Protón disociable

NH3 H átomo de carbono reactivo

C C -S
N C-CH2-N O- O-
H3C-C C-H C=C-CH2-CH2-O-P-O-P-O-
N O O

- -
O O R O O R
C N+-C-CH3 C N+-C-CH3
H+ + ẟ-O=C ẟ - + ƟC HO-C-C
CH3 S- C CH3 S-C
R´ R´
 O- O R R R
C N+-C-CH3 CO2 N-C-CH3 N+-C-CH3
Ɵ
HO-C-C HO-C=C HO-C-C
CH3 S- C CH3 S-C CH3 S- C
R´ R´ R´

OH CH3
H3C-CƟ C=O
Ɵ
C S S H C HS S H
S N+-R + CH2 C S N+-R + CH2 C
C C CH2 R C C CH2 R
R´ CH3 R´ CH3