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PHARMACOLOGY
SECTION #1
1. A patient is ordered an injection of 80mg of Pethidine. Each stock ampoule 100 mg per 1ml. How
much will you draw up?
3. A patient is prescribed 1L of a Saline solution. The rate is set at 100ml/hr. How long will the
infusion take?
4. How many 300 mg tablets are required for a prescribed dose of 450 mg?
5. A doctor orders Penicillin via Potassium oral suspension 56 mg/kg/day in four doses per day for a
child who weighs 25 kg. The suspension available is 125mg/5ml. What volume should be
administered at each dose?
6. The patient is ordered Amisulpride Tablets. Order is 1200mg Mane, the tablets come in 400mg.
How many tablets do you administer?
7. The patient ordered Coversyl Plus 2.5 mg Mane. Coversyl comes in 5mg Tablets. How many
tablets do you give?
9. A 2 year old child is ordered Painstop (120 mg Paracetamol/Codeine Phosphate 5 mg/5ml). The
child is ordered 5 ml Painstop every 6 – 8 Hours. How many mls do you administer?
10. A patient has returned from theatre with Nausea. The PRN order is for Ondansetron IMI. The
order is for 6 mg, the Ondansetron comes in 4 mg/2ml. How many mls do you draw up?
11. Calculate the size of a single dose if a child weighing 20 kg is ordered Flucioxacillin 100
mg/kg/day. 4 doses per day?
13. A 5 Year Old Girl is ordered paracetamol stat. The pharmacy guidelines recommend 15 mg/Kg.
The child weighs 25 Kg. Stock is 125 mg/5ml. How many ml will the child receive?
14. A 1000 ml bag of Hartman's is to be infused over 18 hours. What is the flow rate?
16. A child requires 50 milligrams of Phenobarbitone. If stock ampoules contain 200 mg in 2 ml, how
much will you draw up?
17. What volume is required for the injection if a patient is ordered 500 mg of Capreomycin
Sulphate, and each stock ampoules contains 300 mg/ml?
18. A patient needs 5000 mg of medication. Stock solution contains 1 g per 1ml. What volume is
required?
19. A teenager is prescribed 1000 mg of Chloramphenicol, stock on hand contains 250 mg/10ml in
suspension. Calculate the volume required?
20. How many 25 mg tablets are required for a prescribed dose of 0.05 g?
21. Calculate the size of a single dose if a child weighing 15 kg is ordered Flucioxacillin 100
mg/kg/day. 4 doses per day.
22. 500 ml is to infuse over 5 hour period. Find the flow rate in ml/h?
23. A child weighing 45 kg requires antibiotics which are ordered 75 mg/kg. How much will the child
get in a single day if there are 3 doses a day?
24. An adult is to be administered 500 ml of blood in 3 hours. What is the mls/hr required to
administer in the required time?
25. A 100 ml bag of Metronidazol is to be administered over 30 minutes. What is the mls/hr to
achieve this?
SECTION #2
3
1. If 250 mL of a 1:800 (v/v) solution were diluted to 1000 mL, what would be the ratio
strength (v/v)?
ANSWER: 1:3200
ALTERNATELY,
Q1 X C1 = Q2 X C2
2. If 400 mL of a 20% w/v solution were Epinephrine diluted to 2 liters, what would be the per-
centage strength (w/v)?
ANSWER: 4%
Q1 X C1 = Q2 X C2
3. If 150 mL of a 17% (w/v) concentrate of benzalkonium chloride are diluted to 5 gallons, what
will be the ratio strength the ratio strength (w/v) of the dilution?
ANSWER: 1:742
To solve this problem, you must first find out how many mls are in 5 gallons ?
Q1 X C1 = Q2 X C2
4. If two tablespoonfuls of povidone iodine solution (10% w/v) were diluted to 1 quart with
purified water, what would be the ratio strength (w/v) of the dilution?
To solve this problem, you must first do conversions: tablespoons to mls ! => 1 tbs = 15 mls, and
2 tbs = 30 mls, also convert quarts to mls = 1 quart = 946.3 mls
Q1 X C1 = Q2 X C2
(a) 2% v/v
(b) 2% w/v
(c) 1.96% w/v
(d) 0.39% w/v
ANSWER: 0.39%
6. A blood volume expansion solution contains 6% (w/v) of hetastarch and 0.9% (w/v) of
sodium chloride. How many grams of each agent would be present in 250 mL of the
solution?
X = 15 gms of hetastarch
And
SECTION #3
1. A DEA number is assigned to authorized prescribers, which allows them to write
prescriptions for controlled substances. The number portion has 6 digits plus a check digit.
In the following DEA number, what would the check digit be: BC765432__?
A. 1
B. 6
C. 3
D. 9
Step #1: 7 + 5 + 3 = 15
Step #2: 6 + 4 + 2 = 12
Step #3: STEP#2 x 2 = 12 x 2 + 24
STEP#4: STEP#1 + STEP#3 = 15 + 24 = 39
THEREFORE, THE CORRECT ANSWER IS LETTER “D”, SINCE THE LAST DIGIT IS “9”
2. Dr. Johnson is a heart surgeon in Accident, Maryland. One of the DEA numbers below is
assigned to him. Which of the following DEA numbers is valid ?
A. BJ8042345
B. BJ5324126
C. AJ7148424
D. AJ7658431
ANSWER:
Meq = mg X Valence
------------------
Atomic Weight
1500 X 1
Meq = ------------- = 20.13
74.5
4. The normal potassium level in the blood plasma is 17 mg% (17 mg/100 mL). Express this
concentration in terms of milliequivalents per liter.
ANSWER:
17 mg% = 17 mg / 100 mL
Expressed per Liter = 17 mg / 100 mL X 10 = 170 mg / 1000 mls
Potassium (K+) = 39.098 = 39 gms / L = 39 mgs / L = 1 Eq = 1 Meq
170 mgs X 1
Meq / L = ----------------- = 4.39 meq / L
39 mgs
5. How many grams of sucrose must be added to 475 mL of water to make a 65% (w/w)
solution?
ANSWER:
100 % - 65 % = 35 %, Therefore
35 475 (65)(475)
--- x ------- = 35X = (65)(475) = X = ------------ = 882.14 gms 35 : 475 :: 65 : X
65 X 35
8
ANSWER:
MgSO4—m.w. 120
5 Meq Mg ++ / L
Since Mg++ valence is 2, then 120 / 2 = 60 mgs, and
ANSWER:
NH4Cl—m.w. 53.5
2% w/v solution = 2 gms / 100 mls = 0.02
8.
ANSWER:
222 mgs of C2H3NaO3 (at.wt.82)
15 mgs of MgCl2 (at.wt. 95)
Volume = 100 mls
15 mgs X 2
Meq Mg++ = ------------------ = 0.316 Meq / L
95