Tujuan

In general this book is intended to provide information about therapy

tuberculosis and the medicine.

In particular, it is hoped that this book can be used as a source

practical information for Pharmacists in order to support treatment

tuberculosis in Indonesia, through:

1) Information material in the context of communication / consulting services, information

and education (IEC) is good for sufferers in direct service on the spot

service

2) Providing information for other health workers, institutions, organizations

profession and society.

3) Provision of anti-tuberculosis drugs that are safe, effective, quality, and able

reached by all levels of society,

Classification of TB is determined with the aim of setting the drug

Antituberculosis (OAT) is appropriate and before treatment is carried out,

TB sufferers are classified according to the Indonesian Ministry of Health, 2014:

a. Anatomic location of the disease

1) Pulmonary tuberculosis is TB that occurs in the ptreatment

parenchyma.

Lymphadenitis TB in the chest cavity or pleural effusion without being present

radiological images that support pulmonary TB, stated

as extra pulmonary TB. Patients suffering from pulmonary TB and

suffering from extra pulmonary TB are classified as pulmonary TB patients.

Treatment history of previous disease

1) New TB patients are patients who have never gotten it

previous TB treatment or had taken medication

Antituberculosis (OAT) but less than 1 month or less

from 28 doses.

2) Patients who have been treated for TB are patients who were previously

have taken OAT for 1 month or more (≥28

dose). Then patients are classified based on results

last TB treatment, namely:

a) Patients relapse are TB patients who have been stated

cured or complete treatment then diagnosed with TB

based on the results of bacteriological or clinical examination.

b) Patients treated again after failure are TB patients

who had been treated then was declared a failure

last treatment.

c) Patients treated again after dropping out of treatment (lost to

follow-up) is a patient who has been treated and stated

lost to follow (this classification was previously known as

treatment of patients after dropping out of treatment).

d) Others are TB patients who have been treated but the results the final treatment of previous
treatment is unknown.

3) Patients whose history of previous treatment is unknown.

c. Classification based on the results of drug sensitivity testing

In this classification patients are grouped based on test results

sensitivity of test samples from Mycobacterium tuberculosis to OAT

and can be:

a) Mono resistance (MR MR) is resistant to one type

First-line OAT.

b) Poly resistance (PR PR) is resistant to more than one type

First-line OAT other than isoniazid (H) and rifampicin (R)

together.

c) Multi drug resistance (MDR TB) is resistant to isoniazid

(H) and rifampisisn (R) simultaneously.

d) Extensive drug resistance (XDR TB) is also MDR TB

resistant to one of the fluoroquinolone and OAT groups

resistance to at least one of the second-line OAT injections

like kanamycin, capreomycin, and amikacin.

e) Rifampicin resistance (TB RR) is resistant to rifampisisn

with or without resistance to OAT another type is detected

use genotypic test (fast test) or phenotype method

(conventional)
Following is the classification of TB according to the Indonesian Ministry of Health, 20011 as follows:

a. Classification based on the results of sputum examination microscopic, namely in pulmonary TB.

1) Positive Acid Resistant Basil (BTA) Tuberculosis

a) At least sputum specimens in the morning

- during (SPS) 2 of the 3 specimens were phlegm results positive.

b) One SPS sputum specimen results from positive smear and shows tuberculosis on the chest X-ray of
the patient.

c) One SPS sputum specimen results from smear and culture of positive TB germs.

d) One or more sputum specimens were positive after 3 SPS sputum specimens on the previous
examination were negative and there was no improvement after administration of non-OAT antibiotics.

) Negative smear pulmonary tuberculosis

b. Classification based on patient's treatment history previously divided into several types, namely:

1) New case

Is a sufferer who has never been treated with OAT or already swallowed less than one OAT month (four
weeks)

2) Relapse (Relapse)

Is a TB sufferer who has previously been received TB treatment and was declared cured or complete
treatment, diagnosed again and the result is smear positive

3)Case after dropping out of treatment (Default)

Patients who have been treated and dropped out of two treatments month or more with positive smear
results.

4) Case after failure (Failure)

Patients whose sputum examination results remain positive or returned to positive in the fifth month or
more so as patients undergo treatment

5) Transfer case (Transfer In)

Patients who were transferred from the UPK had another TB register to continue treatment again.

6) Other cases
All other TB cases not included in the provisions in on. This group includes chronic cases, namely
patients with examination results still show BTA is still positive after finishing treatment reset category 2.