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Boden D.
Science 8A
3 May 2019
Ethics of CRISPR
At the birth of twins Nana and Lulu had the world had it eyes on these two. The twins
had born HIV resistant by the of genome editing using CRISPR technology. This technology has
grabbed the attention of the governments,corporations and people of the world all questioning
the ethical energy of genome editing. This technology has the ability to improve the lives of
millions around the world, but also ruin the ethical state of mankind. CRISPR technology is
being developed and tested on genetically modified products,crops and humans but the ethics of
CRISPR was developed by a team in the US and europe lead by Jennifer Doudna and
Emmanuelle Charpentier. They found that the unique CRISPR DNA has the ability to cut
viruses(Vidyasagar).
CRISPR-Cas9. CRISPR
regularly interspaced
Source:https://www.livescience.com/60938-a-breathtaking-new-gif-shows-crispr-chewing-up-dna.html
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nucleotides” and the Cas9 is the protein the is paired with that allows the microorganism to cut
pieces of the DNA. This microorganism has the ability to cut out strands of DNA or RNA and
replace them with other DNA or RNA. The microorganism enters the cell and in a process of
about 30 seconds can cut out a piece of DNA/RNA(Vidyasagar). This technology is way more
preseice than other gene modifying technology and allows us target genes more specifically.
CRISPR technology is way more advanced than any and will open up the world to many new
opportunities.
Recently a group of scientists using CRISPR extracted spiders dragline silk (spiders web) gene
and put them into goats. Using CRISPR’s accuracy they put they put the silk gene into a spot
were it would produce through the goats milk. The offspring of the goat produced three of the
seven goats positive for the silk gene. Now we collect the extremely strong silk easier and in
large quantities(Zyga). Before it was extremely difficult to try and collect large quantities of this
Source:https://phys.org/news/2010-05-scientists-goats-spider-silk.html
vests and airbags as it is strong but flexible(Zyga). There is the potential to modify many other
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We are expected to have to have feed around 10 billion people by 2050 and CRISPR has
to past genome editing options. By genetically modified Crops we can increase their shelf life
and customer appel(Taylor). Corporations are even looking into genetically modifying plants to
have the shelf life or customer appeal to be sold in market so we can feed our growing
population.
CRISPR technology has now even made to genetically modified humans for a variety of
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reasons. When we first look at genetically modifying humans one of the most beneficial
applications is fixing genetic disorders(Colvin). There has been research done in genetic disorder
such as hunter disease,down syndrome and even rare blood diseases. Though at the moment the
treatment are high risk and they can still be passed through heredity(Colvin). Though in world
with aesthetics of of course the question of whether or not we can modify what our kids look like
has come up. In time with more development we could have the ability to decide how a child
looks even before they are born. In china a set twins was born HIV resistant and a host of other
humans.
Source:https://www.technocracy.news/wp-content/uploads/2019/02/lulu-and-nana-777x437.jpg
After seeing all its applications is hard not deny the fact CRISPR has the potential to help
millions of lives. Though at this point heavy regulations fairly restrictive access has kept this
technology has been keep quiet. As the research and development furthers it will be important
that we control CRISPR with tight regulations. As this technology developed it's best we
understand regulation need to be maybe on a case by case basis as each application has its own
set of ethical boundaries. Through the development in crops and products it difficult as we have
the ability to produce more and better for humans but it's decide at what cost it is to the
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environment .Tim Colvin in the article CRISPR Technology he states “It is important to
remember that scientists in nations with lax bioethical standards will eventually have access to
this technology. It will not remain in the hands of individuals who will be reluctant to use it.” and
“This sort of scientific “arms race” mentality inevitably to science controlling humanity rather
than humanity controlling science,” this shows how if don’t use this technology humanity will
find itself fighting a war it could’ve stopped. For an individual it's best to get educated and just
learn more about how this affects us. For a community to best they advocate for what’s local
issue there how CRISPR could affect it. The most important is how we deal with this on a global
scale we it’s important the come together to have ethical policies for us and the environment we
all stick to but also helping the most people we can with this amazing technology.
As CRISPR technology is being developed and tested on products,crops and human it has
the potential for massive impacts. Though it has still under intense regulations and as the
regulations allow these products to hit the market it's important we regulate each application on
case by cases basis. We see this is important as through modifying the natural resources of
product we can drastically improve their performance but we don’t want to affect the natural
resources. We also saw that if genetically modify crops it could help to feed our growing
population but has the potential to harm nature and humans as we are not fully aware of it effects
on crops. Lastly we have the potential for curing genetic disorders and even change the
biochmerity of humans for aesthetic reason though these come at great risk as we are unaware of
it can do to society but changing what makes us all human. CRISPR technology has the potential
to change the world for billions of people though how regulate and decide what is ethical holds a
lot power because this technology has the ability to change nature and mankind forever
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Works Cited
University,http://www.cbc-network.org/issues/faking-life/crispr-technology/
2017.
Eschner,Kat “We need to Police Gene Editing. The World Health Organization
https://www.popsci.com/gene-editing-WHO-CRISPR-guidelines.
Taylor, Ashley. “Companies Use CRISPR to Improve Crops.” The Scientist, LABX
https://www.the-scientist.com/bio-business/companies-use-crispr-to-improve-crops-
65362
2018,https://www.livescience.com/58790-crispr-explained.html
Zyga, lisa. “Scientist breed goats that produce spider silk.” Phys.org, Science X
https://phys.org/news/2010-05-scientists-goats-spider-silk.html
Image caitions
Source:https://www.technocracy.news/wp-content/uploads/2019/02/lulu-and-nana-777x437.jpg
Source:https://www.livescience.com/60938-a-breathtaking-new-gif-shows-crispr-chewing-up-dna.html
Source:https://phys.org/news/2010-05-scientists-goats-spider-silk.html