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If any balance has the operating range from 0.01 mg to 110 gm then it should be used for weighing the material from 0.01X50 = 0.50
mg to 110X80% = 88.00 gm. Detailed guidance on the balances can be learned through OIMLR76-1 Non-automatic Weighing
Instruments.
But according to USP <41> Weights and Balances, a simple theoretical calculation can be used to calculate the minimum weight for any
balance. To weigh 10 mg sample you have to use 10X0.1% = 0.01 mg least count balance. It shows that if you have a balance with least
count 0.01 mg, you can weigh minimum 10 mg sample on it. Other weights can be calculated accordingly.
Update: Simply you can calculate the minimum limit by multiplying least count by 1000.
Minimum Weighing Limit = Least Count x 1000
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