04. 04. 2019.

Crno sjeme može liječiti hipotireoidizam Hašimotova bolest, klinička

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Depresija: Rješenja 21. stoljeća + Tamna strana pšenice

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04. 04. 2019. Crno sjeme može liječiti hipotireoidizam Hašimotova bolest, klinička

Crno seme može liječiti hipotireoidizam (Hashimotova bolest), otkriva

klinička ispitivanja
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Posted on: Nedjelja, 12. ožujka 2017. u 5:45 am

Napisao: Sayer Ji, osnivač (/gmi-blogs/sayer%20ji)
Views 105503

Ovaj članak je zaštićen autorskim pravima GreenMedInfo LLC, 2018.

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A recent clinical trial indicates that the most common cause of hypothyroidism
(Hashimoto's disease) may be improved with the addition of only two grams of
powdered black seed daily.
A powerful new randomized clinical trial reveals that the ancient healing food known as nigella sativa (aka “black seed”), once known as the
“remedy for everything but death, (/blog/black-seed-remedy-everything-death)” may provide an ideal treatment for the autoimmune
thyroid condition known as Hashimoto’s disease, which is the most common cause of hypothyroidism.

The new study, published in the journal BMC Complementary and Alternative Medicine, evaluated the effects of nigella sativa on thyroid
function, serum Vascular Endothelial Growth Factor (VEGF) - 1, Nesfatin -1 and anthropometric features in patients with
Hashimoto’s thyroiditis (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112739/).

The study took 40 patients with Hashimoto's thyroiditis, aged between 22 and 50 years old, and randomized them into one group receiving
two grams of powdered encapsulated Nigella sativa and the other 2 grams starch placebo daily for 8 weeks.. Changes in anthropometric
variables, dietary intakes, thyroid status, serum VEGF and Nesfatin-1 concentrations were measured.

The positive results were reported as follows:

"Treatment with Nigella sativa significantly reduced body weight and body mass index (BMI). Serum concentrations of
thyroid stimulating hormone (TSH) and anti-thyroid peroxidase (anti-TPO) antibodies decreased while serum T3
concentrations increased in Nigella sativa-treated group after 8 weeks. There was a significant reduction in serum
VEGF concentrations in intervention group. None of these changes had been observed in placebo treated group. In
stepwise multiple regression model, changes in waist to hip ratio (WHR) and thyroid hormones were significant
predictors of changes in serum VEGF and Nesgfatin-1 values in Nigella sativa treated group (P < 0.05)."

The researchers concluded:

"Our data showed a potent beneficial effect of powdered Nigella sativa in improving thyroid status and anthropometric
variables in patients with Hashimoto's thyroiditis. Moreover, Nigella sativa significantly reduced serum VEGF
concentrations in these patients. Considering observed health- promoting effect of this medicinal plant in ameliorating
the disease severity, it can be regarded as a useful therapeutic approach in management of Hashimoto's thyroiditis."

What is Hashimoto’s Disease and Why Does Synthetic T4 Fail To

Improve Well-Being
Hashimoto’s disease can be a devastating condition, especially when treated with a conventional medical approach. Also known as chronic
lymphocytic thyroiditis, it is a progressive autoimmune disease where, in the many cases, the thyroid gland is eventually destroyed. It is
considered the most common cause of hypothyroidism in North America. Some additional salient facts are:

1. About 5% of the U.S. population will be affected by Hashimoto’s thyroiditis at some point in their life.

2 H hi t ’ t 15 ti ft i th i Th hi h td it fH hi t ’ b t 30 d 60
www.greenmedinfo.com/blog/black-seed-may-treat-hypothyroidism-hashimotos-disease-clinical-trial-reveals?fbclid=IwAR3ZFgGhf8PJ4Dig2OLq… 2/11
04. 04. 2019. Crno sjeme može liječiti hipotireoidizam Hašimotova bolest, klinička
2. Hashimoto’s occurs up to 15 times more often in women than in men. The highest density of Hashimoto’s cases are between 30 and 60
years of age.
3. Postpartum thyroiditis occurs in about 10% of patients.

4. Hashimoto’s related hypothyroid is often under-diagnosed because the reference ranges were drawn from an unscreened population
likely inclusive of those already suffering from suboptimal thyroid function or outright dysfunction.

The standard of care is to ‘manage,’ or artificially suppress, modulate, and/or replace hormone levels. Hypothyroidism caused by Hashimoto’s
thyroiditis is most commonly treated with synthetic T4 in an attempt to reduce TSH levels under 5.0 U/ml. This often results in the appearance
of TSH normalization, with downstream adverse effects, and without concomitant improvements in well-being. Dr. Kelly Brogan, MD
(http://kellybroganmd.com/thyroid-whats-mental-health-got/), further elaborates:

“For those who do receive the label of hypothyroid, they remain obliquely objectified by their lab work as their doctors
use synthetic T4 – Synthroid – to attempt to move their TSH within range, more often leaving them symptomatic but
“treated” because of poor conversion to active thyroid hormone (T3) and suppression of natural T3 production because
of their now lower TSH.”

It should be noted that while synthetic T4 is described by its manufacturer to be “identical to that produced in the human thyroid gland
(http://www.rxabbvie.com/pdf/Synthroid.pdf),” it is in actuality quite different. This has to do primarily with the fact that while the primary
structure of amino acids in synthetic thyroxine produced from genetically modified yeast is virtually identical to that produced by the human
thyroid gland, the secondary, tertiary and quaternary folding patterns of that protein may differ in significant ways. Known as the protein’s
conformational state, a slight change in folding structure can alter function profoundly. This could account for widespread reports of
dissatisfaction among those treated with synthetic thyroid versus natural forms extracted from the glands of pigs.

Even if the T4 produced synthetically were identical in structure and function to natural T4, the reality is that virtually all T4 found naturally in
the human body is not found in its free state.

Moreover, T4 is found inextricably bound together with T3, T2, T1, and calcitron, in the extraordinarily complex Thyroxine Binding Globulin
(TBG) protein. Clearly, therefore, pharmaceutical preparations of isolated T4 can not be considered identical to whole-food complexed thyroid
hormones derived from natural extracts.

In a post titled, “Natural Desiccated Thyroid and Synthetic are NOT the Same (http://thyroid-s.com/natural-desiccated-thyroid-and-synthetic-
are-not-the-same/),” from thyroid-s.com, this point is driven home powerfully:

"Da bi se grafički ilustrovale ogromne razlike između prirodnog isušenog štitnjače

(https://en.wikipedia.org/wiki/Desiccated_thyroid_extract) u poređenju sa sintetikom samo T4, molimo vas da
razmotrite ovu grafiku. Ona pokušava da pokaže da su mali hormoni T4, T3, T2, T1 i kalcitonina čvrsto vezani za
veoma velike molekule tiroglobulina kako se nalaze u Zapamtite da je molekul tiroglobulina približno 1.000 puta veći
od T4 molekule, a zatim pokazuje i male T4 molekule koje se nalaze u sintetičkim T4 proizvodima. neka ti odlučiš. "

Štaviše, istraživanje objavljeno 2010. godine u Archives of Pharmaceutical Research (/article/synthetic-thyroxine-products-are-below-100-

purity) pokazuje da su preparati levotiroksina široko kontaminirani stereoizmerom "zrcalne slike" zvanim dekstro-tiroksin na nivou od 1-6%
suve težine. D-tiroksin narušava lijevu 'kiralnost' prirodnog tiroksina i predstavlja snažan, kardiotoksični endokrini disruptor.

Proces stvaranja levotiroksin natrijuma danas je visoko sintetski i uključuje upotrebu širokog spektra hemikalija. Jedan patent
(https://www.google.com/patents/WO2009136249A1?cl=en) opisuje vrtoglavo složen proces na sledeći način:

5-dijodo-4-p-metoksi fenoksi-N-acetil-L-fenil alanin etil ester, g. jedinjenje dobijeno u koraku (f) je O-demetilirani, N-
deacetilirani, i deesterifikovani upotrebom vodenog HI u sirćetnoj kiselini da bi se dobio 3,5-dijodo-4-p-hidroksi
fenoksi-L-fenil alanin praćen sa pripremom hidrohloridne soli ista i izolacija, sušenje h. smještanje soli 3,5-dijodo-4-p-
hidroksifenoksi-L-fenil alanin HCI pomoću metil amina, "

Jasno je da sintetski T4 tretmani, čak i ako su efikasni u suzbijanju TSH, možda neće proizvesti kliničke ishode koji se pretvaraju u poboljšanje
blagostanja. Niti se bave ili rješavaju osnovni uzroci Hashimoto-a, koji uključuju nedostatak selena, netoleranciju pšenice i nedostatak
vitamina D / sunčeve svjetlosti [pogledajte studije o ovim vezama na našoj Hashimotovoj kontrolnoj ploči
www.greenmedinfo.com/blog/black-seed-may-treat-hypothyroidism-hashimotos-disease-clinical-trial-reveals?fbclid=IwAR3ZFgGhf8PJ4Dig2OLq… 3/11
04. 04. 2019. Crno sjeme može liječiti hipotireoidizam Hašimotova bolest, klinička
vitamina D / sunčeve svjetlosti [pogledajte studije o ovim vezama na našoj Hashimotovoj kontrolnoj ploči
(http://www.greenmedinfo.com/disease/hashimotos-thyroiditis) ], zajedno sa širokim spektrom još nepoznatog okoliša, faktore prehrane,

načina života i uma-tijela. Možda ova najnovija studija o crnom semenu pruža novi put za ublažavanje i ispravljanje metaboličkih i endokrinih
faktora koji su poremećeni u Hashimotovoj bolesti, ili barem dopunjavaju konvencionalni tretman sa pristupom zasnovanim na hrani koji može
poboljšati i subjektivne i objektivne aspekte bolesti.

Za više informacija o prirodnim i integrativnim pristupima bolesti štitnjače posjetite sljedeće stranice sa resursima: GreenMedInfo.com:

Hipotireoza (http://www.greenmedinfo.com/disease/hypothyroidism)
Hyperthyroidism (https://www.google.com/url?
sa=t&rct=j&q=&esrc=s&source=web&cd=6&cad=rja&uact=8&ved=0ahUKEwjPhYrOvdHSAhXH8CY
BnUQFgg4MAU&url=http%3A%2F%2Fwww.greenmedinfo.com%2Fdisease%2Fhyperthyroidism&u
Hashimotov tiroiditis (https://www.google.com/url?
sa=t&rct=j&q=&esrc=s&source=web&cd=5&cad=rja&uact=8&ved=0ahUKEwjPhYrOvdHSAhXH8CY
BnUQFggyMAQ&url=http%3A%2F%2Fwww.greenmedinfo.com%2Fdisease%2Fhashimotos-
thyroiditis&usg=AFQjCNHui3JpfWmz8gyEVf4j0XHkp_YioA&sig2=ZtvllsNdUmKsJZClcbL9QA&bvm=
Rak štitnjače (http://www.greenmedinfo.com/disease/thyroid-cancer)
Thyroxine (/toxic-ingredient/levothyroxine)
Da biste saznali više o snažnim zdravstvenim prednostima crnog semena posjetite našu ploču za istraživanje na temu: Nigella Sativa (aka
Black Seed) (/substance/nigella-sativa-aka-black-seed)

Sayer Ji je osnivač  Greenmedinfo.com (http://www.greenmedinfo.com/) , recenzent u  Međunarodnom časopisu za

ljudsku ishranu i funkcionalnu medicinu (http://www.ichnfm.org/publications/index.html) , suosnivač i izvršni
(/gmi-blogs/Sayer Ji)
direktor Systome Biomeda (http://www.systomebiomed.com) , zamjenik predsjednika Odbora  Nacionalne
zdravstvene federacije (http://www.thenhf.com/) , član Upravnog odbora Globalnog ne- GMO Foundation
(http://www.gmofreeglobal.org/en/steering-committee) .  (http://www.systomebiomed.com) (http://www.thenhf.com/)
(http://www.gmofreeglobal.org/en/steering-committee)

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