Sei sulla pagina 1di 7

Chinese Journal of Traumatology 2014;17(5):249-255 . 249 .

Original articles

Minimally invasive percutaneous compression plating


versus dynamic hip screw for intertrochanteric
fractures: a randomized control trial
Cheng Qiang, Huang Wei, Gong Xuan, Wang Changdong, Liang Xi, Hu Ning*

【Abstract】Objective: Intertrochanteric femur group (P<0.01). Among the patients treated with PCCP,
fracture is a common injury in elderly patients. The 3.1% needed blood transfusions, compared with 44.6% of
dynamic hip screw (DHS) has served as the standard those that had DHS surgery (P<0.01). The PCCP group
choice for fixation; however it has several drawbacks. displayed less postoperative complications (P<0.05). The
Studies of the percutaneous compression plate (PCCP) mean American Society of Anesthesiologists score and
are still inconclusive in regards to its efficacy and safety. Harris hip score in the PCCP group were better than those
By comparing the two methods, we assessed their clinical in the DHS group. There were no significant differences
therapeutic outcome. in the mean hospital stay, mortality rates, or fracture
Methods: A total of 121 elderly patients with healing.
intertrochanteric femur fractures (type AO/OTA 31.A1- Conclusion: Due to several advantages, PCCP
A2, Evans type 1) were divided randomly into two groups has the potential to become the ideal choice for treating
undergoing either a minimally invasive PCCP procedure intertrochanteric fractures (type AO/OTA 31.A1-A2,
or a conventional DHS fixation. Evans type 1), particularly in the elderly.
Results: The mean operation duration was Key words: Hip fractures; Osteoporotic fractures;
significantly shorter in the PCCP group (55.2 min versus Surgical procedures, minimally invasive; Fracture
88.5 min, P<0.01). The blood loss was 156.5 ml±18.3 ml fixation, internal
in the PCCP group and 513.2 ml±66.2 ml in the DHS Chin J Traumatol 2014;17(5):249-255

A
high incidence of osteoporotic proximal account for approximately 50%.2 Ninety percent of
femoral fractures among the elderly is a these patients are over the age of 65 at the time of
‘‘modern epidemic’’ and is leading to severe hip fracture and a large proportion already suffer
medical and socioeconomic consequences as both from other major comorbidities.3 Of all fall-related
life expectancy and population size are increasing.1 fractures, hip fractures cause the greatest number
Of all hip fractures, intertrochanteric fractures of deaths and lead to the most severe health
problems and reduced quality of life. Maintaining
the patients’ quality of life is the treatment goal of
DOI: 10.3760/cma.j.issn.1008-1275.2014.05.001
Department of Orthopaedic Surgery, The First Affiliated intertrochanteric fractures, and remains a subject of
Hospital, Chongqing Medical University, Chongqing great interest.
400016, China (Cheng Q, Huang W, Liang X, Hu N)
Outpatient Department, Chongqing Zhongshan At present, the dynamic hip screw (DHS) serves
Hospital, Chongqing 400000, China (Gong X) as the standard and is the most common device
Department of Biochemistry and Molecular Biology,
for fixation of intertrochanteric femoral fractures.4
Molecular Medicine and Cancer Research Center,
Chongqing Medical University, Chongqing 400016, China For this conventional procedure, the lateral vastus
(Wang CD) muscle must be split broadly, which is associated
*Corresponding author: Tel/Fax: 86-23-89011212, 86- with significant soft tissue damage and inevitable
18696761022, Email: 1276321387@qq.com blood loss, both of which may worsen multiple
. 250 . Chinese Journal of Traumatology 2014;17(5):249-255

existing comorbidities of elderly patients. 3 More Surgery using the PCCP device was introduced
importantly, relatively high failure rates (5%-20%) in our hospital in 2004. The first three years were
of re-displacement or collapse treated with DHS considered the “learning curve” period, and patients
for unstable intertrochanteric hip fractures are treated at that time were not included in our study.
reported.5,6 A total of 152 elderly patients with intertrochanteric
hip fracture were admitted to our department and
Minimally invasive surgery is gaining popularity were considered for this prospective, randomized
in modern orthopedic trauma, as it has shown some and controlled trial during the period of October
potential benefits including decreased blood loss 2007 to February 2011. The acquisition of all
and postoperative pain, lower risk of postoperative patients was consecutive. Inclusion criteria were: (1)
morbidity and faster recovery of function.7 These age of 60 years or greater; (2) an intertrochanteric
factors are particularly important for elderly patients fracture amenable to satisfactory reduction (type
to allow early weight-bearing and reduce related AO/OTA 31.A1-A2, Evans type 1); (3) ability to
complications.8 The percutaneous compression plate ambulate independently prior to the fracture with
(PCCP) device, which was developed by Gotfried or without assistive devices. 12 Exclusion criteria
in the late 90’s, is a relatively new system for the were: (1) reversed oblique fractures (type AO/OTA
osteosynthesis of intertrochanteric hip fracture.9,10 31.A3 or Evans type 2); (2) nonunion, pathological
The design of the implant offers minimal operative fractures, or the presence of metastatic disease;
trauma, and only requires two small (2 cm) incisions (3) bilateral hip fractures, previous ipsilateral lower-
in order to insert a plate with a distal beveled end limb surgery, or contralateral hip fracture within the
through the vastus lateralis muscle. The device last year; (4) patients who required intensive care
provides rotational stability and compression of or treatment in other departments; 13 (5) patients
fractures by means of two telescoping neck screws of with diabetes difficult to control. Randomization
relatively small diameter (9.3 mm) and area (68 mm2 was done by nurses who drew a sealed, numbered
each), as opposed to the single bigger screw used envelope containing the treatment method for each
in the DHS. Lateral cortical support is conferred patient prior to surgery. There were 133 patients
by a proximal extension of the locking plate. This who met these criteria, including 5 patients who
minimizes soft tissue damage and blood loss, avoids used aspirin for many years. We replaced aspirin
excessive periosteal stripping and devascularization with low-molecular-weight heparin one week before
of fracture segments.11 surgery and stopped its use one day before surgery.
No patient used warfarin or other anticoagulants
There are only a few studies evaluating the for a long time. For the patients with diabetes, the
efficacy of PCCP, and comparative studies are surgeries were performed until fasting blood-glucose
still inconclusive. This study aims to answer the dropped to 7 mmol/L. No patient was excluded
following questions: Is there any difference in blood for death in the perioperative period. However, 12
loss, transfusion, operation duration, incidence of patients could not be followed up postoperatively
postoperative comlications, length of hospital stay, due to death from other diseases (2 cases) or
fracture healing and Harris hip score between the changing residence (10 cases). Therefore, 121
PCCP and DHS groups? patients were included in our study, of which there
were 65 patients in the PCCP group and 56 in
METHODS the DHS group. All the patients were followed up
postoperatively for 15 months on average (range
All study procedures were approved by the 6-26 months).
hospital ethics committee. All patients gave the
required written informed consent preoperatively. The Baseline data included gender, age, injury
study only recruited patients with an intertrochanteric mechanism, and fracture type according to the
fracture who were mentally competent and gave AO classification, main comorbidities and the
their consent to participate. American Society of Anesthesiologists (ASA) grade
of operative risk.14 We reviewed the AP films of the
Chinese Journal of Traumatology 2014;17(5):249-255 . 251 .

pelvis of all patients to record their bone quality on (Richards Inc. USA) were operated upon via a
the opposite, non-fractured hip, as defined by the standard lateral approach in accordance with the
Singh index (Figure 1).15 Preoperative characteristics manufacturer’s instructions. The PCCP (Orthofix
of patients were recorded in detail in Table 1. Inc. USA) plate was implanted using the technique
described by Gotfried in 2000 (Figure 2).9 A guiding
Table 1. Preoperative characteristics of patients frame was connected parallel to the plate through
PCCP DHS P value which all drills and screws were introduced. A 2-3 cm
Gender (M/F) 28/37 22/34 0.609 incision was made under fluoroscopic guidance by
Age (years) 72.4±4.18 78.6±3.92 0.852 identification of the site opposite to the proximal
border of the lesser trochanter on the lateral aspect
Fracture etiology 0.866
of the thigh. The plate, with its cutting distal edge,
Simple falling 47 40
was inserted beneath the vastus lateralis muscle
Falling from a height 6 7
and attached subperiosteally to the proximal femur
Vehicular trauma 12 9 under fluoroscopic guidance. Through a second
Fracture type (AO/ASIF) 0.790 incision of similar length, a bone clamp was
31 A 1.1 18 15 attached to the guiding frame and the plate was
31 A 1.2 28 24 fixed to the femur under radiographic control. The
first 9.3 mm telescoping hip screw was inserted at
31 A 1.3 3 4
an angle of 135° in the inferior neck border, adjacent
31 A 2.1 10 8
to the calcar femorale. Three self-tapping 4.5 mm
31 A 2.2 4 2
biocortical screws were inserted through the frame
31 A 2.3 2 3 to fix the plate to the femur, followed by the second
Singh index 3.35±0.87 3.24±0.46 0.723 9.3 mm hip screw finally inserted in superior and
Osteoporosis 53 45 0.881 parallel position to the first screw.
Main comorbidity 0.795
The wounds were irrigated with abundant normal
Hypertension 18 15
saline and closed in layers with a drainage system
Coronary heart disease 6 7
in place (Figure 3). The drain was maintained for
Diabetes 8 6
no more than 48 h. Prophylactic antibiotics were
COPD* 3 1 administered and prophylactic low-molecular-weight
ASA grade* 0.841 heparin was given subcutaneously for 6 weeks
I 6 5 postoperatively. Ambulation with partial weight
II 39 31 bearing from the second or third postoperative day
was routine for the patients with stable fractures; but
III 18 19
for all patients with unstable fractures, partial weight
IV 2 1
bearing was delayed until at least 2 weeks after
COPD: chronic obstructive pulmonary disease, ASA: American
surgery. Physical therapy was initiated when each
Society of Anesthesiologists.
patient’s medical condition was stable.
In both groups, patients were positioned in a
standard fashion on the radiolucent orthopaedic The outcome measurements collected for
table to obtain satisfactory closed fracture reduction each patient were operation time, total blood loss
with fluoroscopy control prior to osteosynthesis. A (intraoperative and postoperative drainage) and
posterior reduction device was connected to the transfusion necessity, pain evaluation (using a
table under the patients’ hip to prevent posterior 10-point Visual Analogue Scale, VAS) and length
sagging of the fracture. After successful closed of hospital stay. The criteria for blood transfusion
reduction, assignment to treatment was performed were: hemoglobin lower than 90 g/L with signs
as described above. All participating surgeons and symptoms of low perfusion. The pain-killer
were experienced in both techniques. Patients protocols for the two groups were similar. The VAS
randomized to receive the conventional DHS scores were measured within the first three days.
. 252 . Chinese Journal of Traumatology 2014;17(5):249-255

In addition, postoperative complications during on the affected limb with evidence of bridging
hospitalization and within the first six months callus across the fracture sites on X-ray films. We
following the surgery were collected. Implant-related evaluated functional recovery of the affected limb
failures and mortality were also recorded. using the Harris hip scoring system 6 months after
surgery.
Each patient was reviewed monthly for the
initial 6 months, then 9, 12, 18 and 24 months after Statistical analysis
surgery. The follow-up study included both clinical Comparison of the differences between the two
and radiologic evaluations. X-ray films were taken groups was obtained by Pearson X 2 test, Fisher
for evaluation of position as well as healing of the exact test and independent t-test. SPSS 10.0
fracture and implant (Figure 4). The criteria for statistical software was used to analyze the data. P
fracture union were defined as full weight bearing values less than 0.05 were considered significant.

Figure 1. Initial radiograph of one representative case showing intertrochanteric fracture of the right femur. Figure 2. Implant introduced
through separate proximal and distal incisions. Figure 3. Incisions measured during operation. Figure 4. Postoperative radiograph of the
intertrochanteric fracture stabilized by PCCP.

RESULTS in the DHS group (P<0.01). Two patients (3.1%)


treated with PCCP needed transfusions compared
The preoperative characteristics of both groups with 25 patients (44.6%) that had DHS surgery. All
are shown in Table 1. The PCCP group included fractures in both groups had satisfactory reduction.
65 patients with an average age of 72.4 years (49 Fifty-three of 65 (81.5%) PCCP and 47 of 56 (83.9%)
patients with type AO/OTA 31.A1 and 16 patients DHS had adequate screw positions. There were no
with type AO/OTA 31.A2). The DHS group included significant differences in the rates of satisfactory
56 patients with an average age of 78.6 years (43 reduction and adequate screw position between
patients with type AO/OTA 31.A1 and 13 patients the two groups (P=1.0 and P=0.887, respectively).
with type AO/OTA 31.A2). Both groups are similar in Although the same postoperative analgesia was
gender, age, fracture etiology, fracture type, Singh used in the two groups, the mean VAS score in the
index and major comorbidity (all P>0.50). Pre- PCCP group was lower than that in the DHS group
morbid conditions of the patients were assessed (P=0.028), which demonstrated that there was less
using the preoperative ASA classification. Although pain in the former. The hospital stay of the PCCP
there was a trend towards fewer patients in ASA and DHS group was (7.85±1.82) and (8.20±2.58)
grade II in the DHS group, this difference was not days, respectively. Harris hip score of each patient
statistically significant (P=0.841). was evaluated six months after surgery. The mean
value was (89.6±3.51) points for the PCCP group
Data concerning the hospitalization of the and (84.7±2.65) points for the DHS group (P<0.05).
patients are summarized in Table 2. The average These outcome measures, including surgery time,
surgery time was shorter in the PCCP group (55.2 min± blood loss, blood transfusion rate, mean VAS score
8.4 min) than in the DHS group (88.5 min±14.7 min, and Harris hip score, were more favorable in the
P<0.01). The average total blood loss was 156.5 ml± PCCP group than in the DHS group.
18.3 ml in the PCCP group and 513.2 ml±66.2 ml
Chinese Journal of Traumatology 2014;17(5):249-255 . 253 .

Table 2. Comparison of main clinical parameters DISCUSSION


PCCP DHS
P value
(χ± s) (χ± s) As a result of an aging population, hip fractures
Operation duration (min) 55.2±8.4 88.5±14.7 <0.01 have become an increasing public health issue.
Blood loss (ml) <0.01 At present, the DHS remains the gold standard for
Intraoperative 64.7±15.3 255.6±30.4 treating intertrochanteric fractures. However, the
Drain 90.8±35.5 227.8±45.5 conventional DHS technique has several drawbacks.
Total 156.5±18.3 513.2±66.2
Without minimally invasive techniques, its insertion
demands a wider incision, causing considerable
Patients receiving blood
bleeding and damage of soft tissues, which could
transfusion 2/65 25/56
increase pain and aggravate comorbidities.16 The
Mean VAS score 2.65±1.00 4.93±1.16 0.028 single-axis lag-screw fixation in the femoral head
Length of hospital stay (d) 7.85±1.82 8.20±2.58 0.240 may provide insufficient rotational stability and
Satisfactory reduction 65/65 56/56 1.000 contribute to the risk of cut-out of the screw.17 It is
Adequate screw position 53/65 47/56 0.887 also known to lead to fracture collapse upon weight
Fracture healing 65/65 54/56 0.924
bearing, resulting in posteromedial discontinuity,
followed by poor functional outcome.18
Harris hip score 89.6±3.51 84.7±2.65 0.027

Elderly patients susceptible to intertrochanteric


Serious postoperative complications included
femur fractures often have poor bone quality as
wound infection, pulmonary embolism, cardiac,
well as other major comorbidities. In an attempt to
implant-related failure, etc. Superficial infections
reduce comorbidities and create faster rehabilitation,
were found in five DHS patients (3 patients with
the PCCP, a device for minimally invasive treatment
type AO/OTA 31.A1.2, 2 patients with type AO/
of intertrochanteric hip fractures was developed.19
OTA 31.A2.1) and short term antibiotic regimens
The PCCP is performed using a no-touch technique
cleared all infections. There were no superficial
with decreased tissue exposure. 20 Percutaneous
infections in the PCCP patients. There were no
insertion of PCCP beneath the vastus lateralis by
cases of deep infection or pulmonary embolism in
means of minimizing tissue dissection results in
the two groups. Major cardiovascular complications
less bleeding, reduced wound hematomas and less
including arrhythmia, myocardial ischemia, or
infectious complications, as well as earlier, more
cardiac decompensation and failure were more
rapid and more effective rehabilitation.21
frequent in the DHS group. Two of 56 patients (3.6%)
in the DHS group showed evidence of implant-
The results of this trial demonstrate that the
related failure. One patient (type AO/OTA 31.A1.3)
relatively novel minimally invasive technique
developed a vascular necrosis of the femoral head
and PCCP are effective and provide favorable
following screw cut-out, while the other failure (type
outcomes. We found less blood loss and fewer
AO/OTA 31.A2.1) was a femoral head collapse as a
blood transfusions in the PCCP group, which could
result of lag screw breakage. A hip arthroplasty was
be attributed to the reduced surgical exposure.
required for the first patient, while open reduction
However, the hidden blood loss was not considered
with internal fixation and bone grafting was needed
in our study which may influence the total blood loss.
for the second. Bone healing was achieved within
But the tendency of less blood loss in the PCCP
8 months for both subjects. There was no implant-
group was obvious. Patients in the PCCP group
related failure in the PCCP group. The difference
experienced less postoperative complications such
in fracture healing rate between both groups was
as infection, cardiac events, and implant-related
not significant (P=0.924). In the PCCP group, 64
failure within six months following the surgery in
(98.4%) of the patients had no serious postoperative
this trial. The tendency towards more infectious
complications, compared to 45 (80.3%) of the
complications in the DHS group could be attributed
patients in the DHS group. Overall, the PCCP group
to considerable damage of soft tissues. Other
displayed less postoperative morbidity (P<0.05).
studies indicate that the minimal tissue dissection
. 254 . Chinese Journal of Traumatology 2014;17(5):249-255

and damage characteristic of the PCCP technique is approach, the PCCP procedure provides significant
a possible explanation for a decreased trend toward advantages such as less blood loss, fewer blood
the incidence of postoperative infections in the transfusions, decreased pain, faster recovery of
PCCP group.16 Cardiac events have been reported function and less postoperative morbidity. The PCCP
as the most common and hazardous complications should be considered as a minimally invasive and
of hip fracture surgery, with a rate of 27% in patients viable therapeutic alternative for intertrochanteric
undergoing DHS surgery.22 However, a large-scale fractures (type AO/OTA 31. A1-A2, Evans type 1) in
retrospective study showed a conspicuous decrease elderly patients.
in cardiovascular events in the PCCP group.19 There
is an inevitable correlation between reduced pain REFERENCES
and fewer cardiovascular complications in elderly
patients treated with the PCCP.23 It is possible that 1. Cumming RG, Nevitt MC, Cummings SR. Epidemiology
reduced pain and a higher level of comfort after of hip fractures [J]. Epidemiol Rev 1997;19(2):244-57.
PCCP surgery may facilitate easier postoperative 2. Krischak GD, Augat P, Beck A, et al. Biomechanical
mobilization, and reduce postoperative morbidity comparison of two side plate fixation techniques in an
and mortality.24 These results show fewer incidences unstable intertrochanteric osteotomy model: sliding hip
of implant-related failures in the PCCP group. The screw and percutaneous compression plate [J]. Clin Biomech
most obvious difference from the DHS is that the 2007;22(10):1112-8.
PCCP comprises double telescoping screws, rather 3. Morris AH, Zuckerman JD. National consensus
than a single lag screw. Although the union of this conference on improving the continuum of care for patients with
double axis fixation decreases sliding, it can allow hip fracture [J]. J Bone Joint Surg Am 2002;84(3):670-4.
more efficient control of fracture impaction, providing 4. Janzing HM, Houben BJ, Brandt SE, et al. The Gotfried
greater primary stability and better fracture healing.10 percutaneous compression plate versus the dynamic hip screw in
It is also hypothesized that the small diameter of the the treatment of pertrochanteric hip fractures: minimal invasive
holes at the drilling site used with the PCCP may treatment reduces operative time and postoperative pain [J]. J
be responsible for preservation of the lateral wall Trauma 2002;52(2):293-8.
and reduction of fracture collapse.9 Many authors 5. Ahrengart L, Tornkvist H, Fornander P, et al. A
have also published beneficial outcomes with less randomized study of the compression hip screw and Gamma
pain and improved weight bearing using PCCP, nail in 426 fractures [J]. Clin Orthop Relat Res 2002;(401):209-
supporting this idea of better stability in the early 22.
phase of fracture healing.9,13,16 6. Dujardin FH, Benez C, Polle G, et al. Prospective
randomized comparison between a dynamic hip screw and a
Due to its percutaneous method of insertion, mini-invasive static nail in fractures of the trochanteric area:
it is thought that minimal exposure and periosteal preliminary results [J]. J Orthop Trauma 2001;15(6):401-6.
stripping and preservation of soft tissue coverage 7. Browner BD, Alberta FG, Mastella DJ. A new
would provide optimum conditions for fracture era in orthopedic trauma care [J]. Surg Clin North Am
union. 25 These factors may decrease bleeding 1999;79(6):1431-48.
and postoperative pain, provide faster recovery of 8. Ropars M, Mitton D, Skalli W. Minimally invasive
function and result in lower postoperative morbidity. screw plates for surgery of unstable intertrochanteric femoral
Strict adherence to each detail of performing the fractures: a biomechanical comparative study [J]. Clin Biomech
PCCP procedure is crucial to prevent possible 2008;23(8):1012-7.
mechanical problems.16 The correct positioning of 9. Gotfried Y. Percutaneous compression plating
the patient, maintenance of posterior reduction, of intertrochanteric hip fractures [J]. J Orthop Trauma
correct alignment of the aiming guide and inserting 2000;14(7):490-5.
of the two telescoping screws, are all crucial steps to 10. Gotfried Y. Percutaneous compression plating
ensure long-term fixation. for intertrochanteric hip fractures: treatment rationale [J].
Orthopedics 2002;25(6):647-52.
In conclusion, the present study demonstrates 11. Yang E, DeLaMora S. Minimally invasive treatment of
that, when compared with the conventional DHS intertrochanteric hip fractures with the Gotfried percutaneous
Chinese Journal of Traumatology 2014;17(5):249-255 . 255 .

compression plate [J]. Orthopedics 2008;31(1):29-36. compression plating (PCCP) versus the dynamic hip screw for
12. Adams CI, Robinson CM, Court-Brown CM, et al. pertrochanteric hip fractures: preliminary results [J]. Injury
Prospective randomized controlled trial of an intramedullary nail 2002;33(5):413-8.
versus dynamic screw and plate for intetrochanteric fractures of 20. Peyser A, Weil Y, Brocke L, et al. Percutaneous
the femur [J]. J Orthop Trauma 2001;15(6):394-400. compression plating versus compression hip screw fixation
13. Peyser A, Weil YA, Brocke L, et al. A prospective, for the treatment of intertrochanteric hip fractures [J]. Injury
randomised study comparing the percutaneous compression 2005;36(11):1343-9.
plate and the compression hip screw for the treatment of 21. Bensafi H, Laffosse JM, Giordano G, et al. The
intertrochanteric fractures of the hip [J]. J Bone Joint Surg Br percutaneous compression plate (PCCP) in the treatment of
2007;89(9):1210-7. trochanteric hip fractures in elderly patients [J]. Acta Orthop
14. Owens WD, Felts JA, Spitznagel EL Jr. ASA physical Belg 2006;72(3):314-9.
status classification: a study of consistency of ratings [J]. 22. Lawrence VA, Hilsenbeck SG, Noveck H, et al. Medical
Anesthesiology 1978;49(4):239-43. complications and outcomes after hip fracture repair [J]. Arch
15. Singh M, Nagrath AR, Maini PS. Changes in trabecular Intern Med 2002;162(18):2053-7.
pattern of the upper end of the femur as an index of osteoporosis 23. Matot I, Oppenheim-Eden A, Ratrot R, et al.
[J]. J Bone Joint Surg Am 1970;52(3):457-67. Preoperative cardiac events in elderly patients with hip
16. Panesar SS, Mirza S, Bharadwaj G, et al. The fracture randomized to epidural or conventional analgesia [J].
percutaneous compression plate versus the dynamic hip screw: a Anesthesiology 2003;98(1):156-63.
meta-analysis [J]. Acta Orthop Belg 2008;74(1):38-48. 24. Mnif H, Koubaa M, Zrig M, et al. Elderly patient’s
17. Kuzyk PR, Guy P, Kreder HJ, et al. Minimally invasive mortality and morbidity following trochanteric fracture. A
hip fracture surgery: are outcomes better [J]? J Orthop Trauma prospective study of 100 cases [J]. Orthop Traumatol Surg Res
2009;23(6):447-53. 2009;95(7):505-10.
18. Varela-Egocheaga JR, Iglesias-Colao R, Suarez- 25. Kosygan KP, Mohan R, Newman RJ. The Gotfried
Suarez MA, et al. Minimally invasive osteosynthesis in stable percutaneous compression plate compared with the conventional
trochanteric fractures: a comparative study between Gotfried classic hip screw for the fixation of intertrochanteric fractures of
percutaneous compression plate and Gamma 3 intramedullary the hip [J]. J Bone Joint Surg Br 2002;84(1):19-22.
nail [J]. Arch Orthop Trauma Surg 2009;129(10):1401-7.
19. Brandt SE, Lefever S, Janzing HM, et al. Percutaneous (Received December 20, 2013)
Edited by Song Shuangming

Potrebbero piacerti anche