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Dr.

GK 1
Dr.GK 3
Cell – Life and Disease starts from
here…..
From Balance to Imbalance….

Dr.GK 4
LIFE…
• Life is a collection of events….

• Let us make it Colorful


though healthy body and
mind…

• Let us think about Ayurveda

• May we start the journey


through Panchakarma…

Dr.GK 5
Clinical Exploration of
Panchakarma

Dr. P. K. V. Anand MD
MD - Kayachikitsa
Assistant professor
Dept of Samhitha & Sidhantha
Vaidyaratnam Ayurveda College
Thaikkattussery, Ollur,Thrissur.
pkvanand@gmail.com
Ayurvedic Treatment
• TWO DOMAINS

• Samana

• Sodhana

• Panchakarmas are the methods of


BIOPURIFICATION
Dr.GK 7
Samana Sodhana

Removes doshas from


Pacifies doshas locally
body

Comparitively of Effect lasts for long.


temporary action. Done in prabhoota
Done in alpa dosha & dosha & pravara bala.
alpa bala.

Does not interfere much Normalises dhathu


with dhathoos Dr.GK functions. 8
Effects Of Elimination Therapies
Sodhana – Order of events
• Poorvakarma

• Pradhanakarma
- Panchakarmas

• Paschatkarma
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Poorvakarmas
• Pre operative
procedures

• Snehana and Swedana

• Must before
Sodhanakarma
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Snehana
• Internal
administration

• External
Administration

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Swedana
• Agneya and Anagneya

• Ekanga and Sarvanga

• Ruksha and Snigdha

Dr.GK 13
Kerala Special Treatments

• They are the combinations


of Snehana and Swedana
• They are the modified
therapeutic procedures
• They can be done as
poorvakarmas and Samana
chikitsa in specific
conditions

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Panchakarmas – Purification
methods
• FIVE in number

• 1. Vamana – Emesis
• 2. Virechana – Purgation
• 3. Vasthi – Medicated enema
• 4. Nasya - Nasal drug administration
• 5. Rakthamoksha – Blood letting (Leech
therapy)
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Why Panchakarmas…???

• The real pathogenesis breaker….

• Long standing effects….

• Less chance of recurrence….

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Where are the changes in the
patient….???
• Doshas
• Dooshyas
• Srothuses
• Agni
• Ojus

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Where are the changes in the
patient….???
• Cell
• Tissues
• Channels
• Systems…
• Hormones..
• Enzymes..
• Electrolytes
• Body fluids
• Osmosis
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Vamana

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Water nourishes the nature… And
keeps it clean by removing the
wastes……

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The Therapeutic profile…..

Vamana is the therapeutic


procedure where forceful
expulsion of vitiated doshas
occurs through mouth following
administration of
Vamanoushadhi…..

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Therapeutic targets

• Kapha dosha elimination

• Srothosodhana

• Dhathusudhi

• Agnideepthi
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Common Conditions Where
Vamana is Practiced
• Skin diseases - Psoriasis, Urticaria, Eczema,
Allergy, Acne…..

• Bronchial Asthma

• Depression, Anxiety neurosis

• Hypothyroidism

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Mechanism of Action- Vamana

• Central emesis- By stimulating the vomiting


centre situated in Medulla

• Reflex emesis- irritation of the gastric


mucosa stimulates the Vomiting centre
through Vagus and sympathetic pathways

Probably both actions can be seen with the


Vamanoushadhi
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Here are the cases…

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Vamana in Bronchial Asthma
Vamana in Bronchial Asthma

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Vamana in Psoriasis
Vamana in Psoriasis

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Therapeutic goals…
• Useful in –

• Obstructive pathologies

• Immune challenges

• Allergic states
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Virechana
Keep the body fluids clean and
pure for a healthy life…….

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The Therapeutic profile…..
• Virechana is a procedure in which the
prakupita doshas are expelled through
adhomarga by the administration of
medicines through oral route.

• Medicines are used in different forms


like choorna, Kwadha, Sneha, Lehya
etc, depending on the condition of the
patient.
Dr.GK 34
Therapeutic targets

• Pitha dosha elimination

• Raktha prasadana

• Vathanulomana

• Agnideepthi
Dr.GK 35
Common Conditions Where
Virechana is Practiced

• Inflammatory skin diseases


• Ascitis
• Diseases of lower GIT
• Neurological diseases
• LBP
• Allergic/Toxic states…

Dr.GK 36
The Common Virechana drugs –
Avipatti Choorna with honey – 20-40 gm

Bahushala guda
Trivrut lehya 20-40 gm
Manibadra guda

Patolamooladi kwatha – upto 90-180ml

Eranda taila preparations – 25-50 ml


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Mode of Action
• Removes the vitiated doshas
• Gradual enhancement of
metabolic power
• Detoxification
• Correction of hormonal
abnormalities…
• Correction of circulatory
problems…

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Nasya
Dr.GK 39
A drop too has it’s effect……
One which is medicated will have
more….

Dr.GK 40
Nasya - Therapeutic Profile
This is a
procedure wherein
medicaments are
instilled into nasal
cavity to expel
doshas pertaining to
Uthamanga

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Key Point
• Fix your Clinical
target…
• Options are –
• Purification
• Nourishment
• Stimulation
• Strengthening…
Dr.GK 42
Nasya - Practical Indications
• Cervical Spondylitis
• Frozen Shoulder
• Hemiplegia
• Facial Palsy
• Seizure diseases
• Mental diseases
• Head aches
• ENT conditions….
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NASYA – Drugs of Choice

• Ardita – Dhanwantharam
Avarthi

• Ksheerabala Avarthi

• Karpasasthyai

Dr.GK 44
Head Ache - Pathologies

Ksheerabala Avarthis

Varanadi ksheeraghrita

Shadbinduthaila

Dr.GK 45
Nasal Pathologies
• Anutaila

• Surasadi

• Thulasikalka

Dr.GK 46
Epistaxis

• Durvasvarasa
• Swarasa of Dadima
Pushpa
• Swarasa of Amrasthi

Dr.GK 47
Apasmara -
Dronapushpi swarasa

Visha, Moha-
Vilwadi gulika

Dr.GK 48
Vyanga – Cosmetic Issues

Kumkumadi taila

Dr.GK 49
Some more examples….

• Hair Problems –
Bhringaraja swarasa

• Premature greying –
Nimba thaila

Dr.GK 50
Nasya – Mental Health

Depression

Lasuna swarasa
Vacha
+Hingu
Vacha
+Jatamamsi

Dr.GK 51
Nasapana…???

• In Aphasia, Facial Palsy etc

• Mashathmagupthadi kzm
• Mashabaladi kzm
• Done with syringe
• Maximum 80ml in both nostrils
• Same poorvakarmadis as Nasya
Dr.GK 52
Pharmaco kinetics
• Routes of Action –

• Nasal mucosa- Kapha


• Nasal Vascular - Pitha
compartment
• Olfactory filaments- Vatha

Dr.GK 53
Mode of Action

• Stimulation of vital
centers
• Nourishing the tissues
• Clearing the channels
• Removes the congestion
• Correcting the neuro-
vascular anomalies Dr.GK 54
Researches - Transnasal drug
delivery to brain
• Absorption through nasal mucosa is
quite rapid
• An aerosol containing a biologically
active ingredient can make it more
faster…
• Avoiding the problems met by blood
brain barrier…
• Avoidance of enzymatic inactivation,
low pH, hepatic extraction, chemical
degradation etc..

Dr.GK 55
Effect of Nasya in Kamala

Dr.GK 56
When Uthamanga gets fire –
You need a Nasal Shower…..

Dr.GK 57
Vasthi
Dr.GK 58
Vasthi- Therapeutic Profile

The word Vasthi is named so


because the vasthi or the urinary
bladder is used to inject the
medicinal material into the rectum,
urethra and vagina.

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Therapeutic targets

• Pakwasayagatha vatha
spectrum

• Vatha domination

• Deep seated pathologies

Dr.GK 60
Three fold utility of Vasthi

• Utklesana – Excitation of dosha

• Purification - Elimination of dosha

• Samana – Pacification of dosha

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Vatha Vs Asthi
Vasthi Yogas
• Vaitharana vasthi

• Saindava – 15 gm
• Jaggery -30 gm
• Tamarind -60 gm
• Thaila -120 ml
• Milk or
Gomoothra – 240 ml

• Indications- Amavatha,Kateegraha
Dr.GK 63
Dr.GK 64
Pichavasthi
• Milk decoction of Salmali vrinda - 240
ml

• Dadimadi or Charngeryadi ghritha – 120


ml

• Indication - Ulcerative
Dr.GK
colitis 65
Dr.GK 66
Madhuthailika Vasthi
• Honey – 4 Palas
• Thaila – 4 Palas
• Erandamoola kwadha – 9.5 Palas
• Misi kalkka – ½ Pala
• Saindava - 1 Karsha

• Indications - RA
Dr.GK 67
Rajayapana Vasthi
• Mustha,pata - 18 drugs
8 madana phala - Decoction in milk 650 ml
• Mamsarasa – 100 ml
• Saindava - 15 gm
• Ghee – 100 ml
• Honey -100 ml
• Kalkka – 30 gm

• Infertility,impotency,extrapyaramidal
disorders A
Dr.GK 68
Mashathmagupthadi Yapana Vasthi
• Masha,Athmaguptha + Milk 600 ml- Ksheerapaka
Bala,Aswagandha
Saindava - 15gm
Mahamashathaila -120ml
Honey -120ml
Rasnadasamoola ghritha -120ml
Kalka-Masha,athmagupta…. -25gm

PARKINSONISM

Dr.GK 69
Dr.GK 70
Thiktha Ksheeravasthi in
Osteoporosis

Gugguluthikthaka Ksheera + Ksheera -120ml


Honey -120ml
Kethakimooladithailam -120ml
Gugguluthikthaka ghritha -120ml
Snehavasthi with Lakshadi mezhukupaka-120ml

Dr.GK 71
Rooksha Vasthi
• Amruthotharam
Kashayam -
300 ml

• Shaddharana choorna
-30gm

• Amavatha
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Dr.GK 73
Yogavasthi with Rasnasapthakam
kashayam
• Makshika - 15gm
• Saindava -12gm
• Dhanwantharam thaila -240ml
• Sathahwa kalka -30gm
• Rasnasapthakam kashayam -300 ml

• Kadeegraha
Dr.GK 74
Mechanism of Action
• Intestinal movements
• Intestinal Absorption
• Intestinal Secretion
• Gut brain – Brain relation
• Regulatory peptides
• Intestinal bacterial flora

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Rakthamoksha

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When Rakthamoksha..?

• Seat of doshas in Sakha

• Preferably after sodhana

• Other treatments bring


Anupasaya

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Raktha dushti Vs Inflammation

• Vascular and Cellular events of


inflammation
• -Transient vasoconstriction
• -Persistent progressive Vasodilatation
• -Increased local hydrostatic pressure
• -Stasis of circulation
• -Leucocytic margination
Dr.GK 78
Inflammation - Pitha
predominant Sannipatha
condition

Healing - Kapha oriented


Repair process

Dr.GK 79
Jaloukaavacharana - Stages

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Multifactorial effect….

• Blood clot is removed


• Local circulation is improved
• Clearance of wastes
• Venous return is increased
• Speed up the repair process

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Components of medicinal leech saliva that exert
effects in the host's body are:

• Hirudin - Inhibits blood coagulation by binding to


thrombin

• Calin - Inhibits blood coagulation by inhibiting


collagen- mediated platelet aggregation

• Destabilase - Dissolves fibrin. Thrombolytic effects


Dr.GK 82
• Bdellins - Anti-inflammatory. Inhibits
trypsin, plasmin, acrosin

• Hyaluronidase - Increases interstitial


viscosity. Antibiotic

• Tryptase inhibitor - Inhibits proteolytic


enzymes of host mast cells
Dr.GK 83
• Carboxypeptidase A inhibitors - Increases
the inflow of blood at the bite site

• Histaminelike substances - Vasodilator.


Increases the inflow of blood at the bite
site
• Acetylcholine - Vasodilator

• Anesthetics substance - Anesthetic


Dr.GK 84
Mode of action

Vathasonitha -

• Pitharakthaprasadana
• Vathanulomana
• Checks the inflammation
• Improves circulation
• Venous diseases and
thrombosis Dr.GK 85
Kushta
• Normalizing Twak sara

• Preventing sakhagathi of
doshas

• Bhrajaka pitha prasadana

• Kledaharana Dr.GK 86
Jaloukaavacharana – different
cases

Dr.GK 87
Triple level action
Raktha- Rakthavaha
Pitha srothus-
Kapha

Rakthagathi - Vatha
Dr.GK 88
Let them drink for OUR
Health….

Dr.GK 89
Panchakarma – The ultimate
benefits
Dhathus are nourished better
through clear srothuses….

Sara of all dhathus are


enhanced…

Ojus is kept away from


Vyapathas….
Dr.GK 90
No ‘ Sanga… ’ Good ‘ Gathi…’
Relax and Refresh till the
next module…..

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