117 MYSTERIES SOLVED AND POSTED BY DR.

WAQAR YOUNIS SO FAR IN GRP

1-Pain of Appendicitis is felt around umbilicus through.

A. Sensory nerve T10
B. Sensory nerves T11 n T 12
C. Sympathetic through T10✔✔
D. Parasympathetic
2-Rupture of #membranous urethra urine leaks into?
A. Deep perineal pouch✔✔
B. Superficial perineal pouch
C. Scrotum
D. Ant abdominal wall
3-Rupture of #bulbar urethra urine leaks into?
A. Deep perineal pouch
B. Superficial perineal pouch✔✔
C. Scrotum
D. Ant abdominal wall
4-Rupture of #penile urethra urine leaks into?
A. Deep perineal pouch
B. Superficial perineal pouch
C. Scrotum✔✔
D. Ant abdominal wall
5-A young man suffer injury to lacerate #penile urethra. After perineum where #else urine will be
leaked
A. Deep perineal pouch
B. Superficial perineal pouch
C. Scrotum
D. Ant abdominal wall✔✔
6-Cardiovascular change in geriatric
A. systolic hypertension✔
B. diastolic hypotension
C. decrease elasticity of myocardial
D. diastolic hypertension
7-Flexor sheath of thumb contain
A. flexor pollicis longus
B. flexor pollicis longus and abductor pollicis longus
C. flexor pollicis brevis
D. flexor pollicis longus, synovial memb and vanicula✔
8-Fibrous flexor sheath of thumb contain
A. flexor pollicis longus✔
B. flexor pollicis longus and abductor pollicis longus
C. flexor pollicis brevis
D. flexor pollicis longus, synovial memb and vanicula
9-SA node acts as a pacemaker of the heart because of the fact that it:
A. Is capable of generating impulses spontaneously.
B. Has rich sympathetic innervations.
C. Has poor cholinergic innervations.
D. Generates impulses at the highest rate✔
10-Which of the following is not a feature of PDA
A. more common in females
B. when associated with pulmonary stenosis its patency is advantageous to the child
C. there is continuous machinary murmur in 2nd left intercostal space with thrill
D. ECG is #usually abnormal✔
E. pulse is of high volume.
11-Nucleoli in active protein synthesis?
A. Prominent nucleolus ✔
B. Appear dense
C. Heterochromatin
D. Diasppear
E. None
12-Which drug do not cause gynaecomastia:
A. Digoxin
B. Griseofulvin
C. Cimetidine
D. Androgen✔
E. Spironolactone
13-Highest diffusing capacity across respiratory membrane and in body fluids is
A. helium
B. carbon monooxide
C. carbon dioxide✔
D. nitrogen
E. Oxygen
14-In anterior duodenal perforation the contents will go to
A. right iliac fossa ✔
B. left iliac fossa
C. anterior sub hepatic space
D. posterior sub hepatic space
E. small bursa
15-In anterior duodenal perforation the contents will go to
A. right para colic gutter ✔
B. right iliac fossa
C. anterior sub hepatic space
D. posterior sub hepatic space
E. small bursa
R para colic gutter >> R iliac fossa
16-Anion gap is difference between?
A. Measured anion and measured cation
B. Measured cation and unmeasured anion
C. Unmeasured cation and unmeasured anion✔
17-Intestinal obstruction caused by carcinoma colon most likely involves
A. Cecum
B. Ascending colon
C. transverse colon
D. Sigmoid colon✔
18-Most common remnant of allantois:
A. urachal cyst✔
B. urachal fistula
C. urachal sinus
19-Patent lumen of allantois:
A. urachal cyst
B. urachal fistula✔
C. urachal sinus
20-Patent lumen of allantois in #inferior part or #superior part #only.
A. urachal cyst
B. urachal fistula
C. urachal sinus✔
21-Patent #local area of allantois:
A. urachal cyst✔
B. urachal fistula
C. urachal sinus
22-The most likely cause of hypercalcemia in malignancy
A. parathormone related proteins
B. parathormone
C. calcitonin
D. bone metastasis✔✔
23-Drugs which produce postural hypotension include?
A. Propranolol
B. Phenoxybenzamine✔✔
C. Halothane
D. Clonidine
24-Structures arranged behind the bladder from
Lateral to medial?
A. Ureter,seminal vesicles,ampulla of vas deference✔✔
B. Seminal vesicles. Ureter.ampulla of Vas deference
C. ampulla of Vas deference .Ureter .Seminal vesicle
D. seminal Vesicle. Vas deference. Ureter
E. Vas defernce .Seminal Vesicle. Ureter
Just remember USA.. ureter.seminal.ampulla of vas
25-During inspiration what decreases
A. heart rate
B. venous return
C. arterial pulse
D. pulse pressure
E. negative intra pleural pressure✔✔
26-Most common cause of cell injury in our country...
A. alcohol
B. hypoxia
C. ischemia
D. radiation
E. malnutrition✔✔
27-Most common cause of cell injury worldwide...
A. alcohol
B. hypoxia ✔✔
C. ischemia
D. radiation
E. malnutrition
28-Factor responsible for patient having two hearts..
A. Allograft
B. Autograft
C. xenograft
D. isograft
E. heterotopic graft ✔✔
29-Erythropoiesis occur in all except..
A. Kidney✔✔
B. Spleen
C. Long bones
D. Flat bones.
E. liver
30-At the end of ventricular contraction, what happens?
A. Aortic valve opens
B. Av valve close
C. Pulmonary valve close
D. Av valve open
E. Aortic valve closes ✔✔
Note..
If aortic valve closes not present in exam. Than pulmonary valve closes 2nd best option
31-Increase in arterial hydrogen ion concentration will stimulate respiratory center through
A. Center chemoreceptor
B. peripheral chemoreceptor✔✔
C. in aortic and carotid bodies
32-Increase in CSF (interstitial fluid) hydrogen ion concentration will stimulate respiratory center
through
A. Center chemoreceptor✔✔
B. peripheral chemoreceptor
C. in aortic and carotid bodies
33-A young boy has lost about 1.5 litter blood in road side accident. He has decreased GFR and
urinary output. The part of renal tubules most involved in bringing back the #GFR and urinary output
to the normal is
A. Descending loop of Henle
B. Distal convoluted tubules✔✔
C. Proximal convoluted tubules
D. Thick ascending loop of Henle
E. Think ascending loop of Henle
34-Renal threshold for Glucose is:
A. 180mg/dl
B. 200mg/dl ✔✔
C. 250mg/dl
35-Renal threshold for Glucose in #arterial blood is:
A. 180mg/dl
B. 200mg/dl ✔✔
C. 250mg/dl
36-Renal threshold for Glucose in #venous blood is:
A. 180mg/dl✔✔
B. 200mg/dl
C. 250mg/dl
37-Glucose begins to appear in the urine when #filtered_load reaches:
A. 180mg/dl
B. 200mg/dl
C. 250mg/dl✔✔
38-A middle age female with recurrent chest infections, long history of diarrhea. On stool
examination cysts of Giardia lamblia were detected. Periferal smear reveals normal T cell but B cells
are slightly decreased. Serum IgA 73, IgG 300 and IgM is 67. What is the most likely Dx?
A. Burton’s agammaglobulinemia
B. Common variable immunodeficiency✔✔
C. HIV infection
D. Cystic fibrosis
39-In bi-temporal hemianopia blockage will be seen in
A. Middle (central) part of optic chiasm✔✔
B. Upper part of optic chiasm
C. Lower part of optic chiasm
40-Lady producing thick saliva.
A. Alpha1 ✔
B. Alpha1 and beta1
C. Beta1 and alpha2
D. Beta2
E. M3
41-when a heavy object in hand is lowered, the extension at elbow is brought about by:
A. Active shortening of extensors
B. Passive shortening of extensors
C. Active lenghtining of flexors✔✔
D. Active shortening of flexors
42-Posterior communicating artery connects
A. ICA with MCA above oculomotor
B. ICA with MCA below oculomotor
C. ICA with PCA above oculomotor✔✔
D. ICA with PCA below oculomotor
43-Posterior communicating artery a branch of
A. Internal carotid✔✔
B. External carotid
C. Middle cerebral
D. Posterior superior cerebellar
44-Patient in abducted hand is asked to move hand slowly and smoothly downward but he dropped
hand suddenly by his side. Which muscle is most likely torn
A. Deltoid
B. Supraspinatus✔✔
C. Subscapularis
D. Teres major
E. Pectoral
45-which of the following is correct about stored blood..
A. Increased2,3dpg
B. Dec O2 affinity
C. platelet deficient
D. Increased hemolysis✔✔
E. Deficiency of factor 3 5 only
46-Most significant cause of atheroma
A. Alcohol
B. Diastolic HTN✔✔
C. Type A personality
D. Type B personality
E. Cholesteatoma
47-A patient undergoes kidney transplant. On first day he was unable to produce urine there is also
tenderness at transplant site.
A. Graft versus host rejection
B. Hyper acute graft rejection
C. Blockage of ureter
D. Renal artery stenosis
E. Thrombus at the site of transplant✔✔
48-A boy had extraction of decidous teeth and now profusely bleeding which classic haemophilia
factor is missing?
A. Factor 9
B. Factor 8 major component
C. Factor 8 minor component✔✔
D. Factor 7
49-One of the most important chemical mediator of inflammation is?
A. Histamine✔✔
B. Prostaglandin
C. Serotonin
D. Neutrophils
E. None
50-Anterior cruciate ligament prevents
A. Ant. dislocation of tibia on femur
B. Post dislocation of tibia on femur
C. Ant. dislocation of femur on tibia
D. Post. dislocation of femur on tibia ✔✔
51-Posterior cruciate ligament prevents
A. Ant. dislocation of tibia on femur
B. Post dislocation of tibia on femur
C. Ant. dislocation of femur on tibia✔✔
D. Post. dislocation of femur on tibia
52-Anterior cruciate ligament while knee joint flexed prevents
A. Ant. dislocation of tibia on femur✔✔
B. Post dislocation of tibia on femur
C. Ant. dislocation of femur on tibia
D. Post. dislocation of femur on tibia
53-Posterior cruciate ligament while knee joint flexed prevents
A. Ant. dislocation of tibia on femur
B. Post dislocation of tibia on femur✔✔
C. Ant. dislocation of femur on tibia
D. Post. dislocation of femur on tibia
👉ACL prevents➡️hyperextension of knee joint
👉PCL prevents➡️hyperflexion of knee joint
54-A patient with pyloric stenosis has chronic vomiting. The most likely biochemical abnormalities in
this would b:
A. High serum bicarbonate
B. Hypokalemia✔✔
C. Hyponatremia
D. Hypovolemia
E. Increased kaliuresis
55- In inferior wall MI which artery should be blocked?
A. Left marginal
B. Diaginal artery
C. Right coronary artery✔✔
D. Right marginal
56- In lateral wall MI which artery should be blocked?
A. Right marginal
B. Diaginal artery
C. Right coronary artery
D. Left circumflex ✔✔
57- In anterior wall MI which artery should be blocked?
A. Left marginal
B. Left ant descending✔✔
C. Right coronary arter
D. Right marginal
58-Internal capsule lies medial to?
A. Putamen
B. Cuadate nucleus
C. Globus pallidus✔✔
D. Amgdaloid nucleus
59-A female had bilateral silicon breast implant placements, now she has arrived with inflammation,
which cells will be demonstrated?
A. Lymphocytes
B. Giant Cells✔✔
C. Plasma cells
D. Neutrophils
E. Eosinophil
60-A couple with first child with down syndrome. Both are young. Father normal. Mother has
robertsonian translocation. What is risk of down syndrome in next baby?
A. 33%
B. 66%
C. 100%
D. 5%✔✔
Ref. Nelson
61-Neurotransmitter for mood
A. Dopamine
B. Serotonin✔✔
C. Acetylcholine
D. Epinephrine
62-Lipoma on thigh ,local anesthetic xylocaine is given which will be affected first?
A. B fibres
B. C fibres✔✔
C. A delta
D. A alpha
63-Bilateral ptosis at the end of the day , confirmatory test A. Tensilon
B. antibodies against ACh receptor
C. EMG✔✔
D. Edrophonium
E. CT scan
64-A young female presented in opd with loss of light reflex but intact accomodation reflex. The
lesion is at
A. Oculomotor nerve
B. Edinger westphal nucleus
C. Pretectal area✔✔
D. Frontal eye field
E. Optic nerve
65-All are vaginal sphincters except :
A. Pubo-vaginalis
B. External urethral sphincter
C. Bulbospongiosus
D. Internal urethral sphincter✔✔
66-Infection of the first web space will be first drained by
A. Epitrochlear lymph node
B. Pectoral group of lymph node
C. Supraclavicular lymph node
D. Infraclavicular lymph node✔✔
67-Mass of hair shaft is mainly due to
A. Cortex✔✔
B. Matrix of nail
C. Basle plus spinosum
D. Sebaceous gland
68-All are features of irreversible cell injury except
A. Karyolysis
B. Karyorhexis
C. Autolysis
D. Shrinkage of mitochondria✔✔
E. Appearance of myeline figure
69-Which one of the following is most likely feature of reversible injury
A. Cell swelling ✔✔
B. Karyohexis
C. Decreased glycogen
D. Myelin figure
70-Sign of apoptosis
A. karyolysis
B. karyorrhexis✔✔
C. pyknosis
D. caseation
71-Apoptosis include the followng except
A. cell swelling✔✔
B. chromatin condensation
C. inc in nuclear size
D. karyolysis
E. rupture of cell membrane
72-Most abundant #astrocytes in #white matter of CNS are?
A. microglia
B. Fibrous astrocytes✔✔
C. Oligodendrocytes
D. Protoplasmic astrocytes
73-Most abundant cells in #Gray matter of CNS are?
A. microglia
B. Fibrous astrocytes
C. Oligodendrocytes
D. Protoplasmic astrocytes✔✔
74-Most abundant cells in white matter of CNS are?
A.microglia
B. Fibrous astrocytes
C. Oligodendrocytes✔✔
D. Protoplasmic astrocytes
75-Most abundant glial cells
A. Astrocytes ✔✔
B. Oligodendrocytes
C. Ependymal cells
D. Schwann cells
76-Aortic dissection is associated with all of the following except??
A. Cystic medial necrosis
B. Hypertension
C. Atherosclerosis✔✔
D. Old age
77-True hermaphroditism
A. XX/XY✔✔
B. XXY
C. XXX
D. XYY
78-Premalignant condition is
A. Mylodisplastic syndrome✔✔
B. Leukoplakia
C. Cervical erosions
D. Psoriasis
79-Basic mechanism involved in aqueous humour production:
A. Active sodium secretion✔✔
B. Passive Chloride absorption
C. Glucose diffusion
D. Ultrafiltration
E. Water secretion by simple diffusion
80-38 year lady has endometrial carcinoma that has involved upto half of the thickness of
myometrium and ovaries.The cancer is in which of the following stages
A. Stage Ia
B. Stage Ib
C. Stage IIc
D. Stage II
E. Stage III✔✔
81-Low frequency hearing loss in a child:
A. Conductive deafness✔✔
B. Neural deafness
C. Sensory deafness
82-Type of Hypersensitivity in hashimoto's thyroiditis
A. Type 1
B. Type 2
C. Type 3
D. Type 4✔✔
83-Milk is notoriusly deficient in
A. Vit c
B. Iron
C. Pantothenic acid
D. Vit a
E. Riboflavin
Ans. C is cpsp key.
A is chatterjea key. So choice is urz
84-DIC is related to all except:
A. Cancer
B. Amniotic fluid embolism
C. Sepsis
D. Oral Contraceptives✔✔
E. Bacteremia
85-A patient has Hb 6, platelet 4,50,000 with hypercellular bone marrow. Diagnosis is?
A. Due to drugs he is using for anemia
B. Leukemia
C. Iron deficiency anemia✔✔
D. G6PD
E. Acute blood loss
86-Major stress hormone is:
A. ACTH✔✔
B. Epinephrine
C. Norepinephrine
D. ADH
87-Hypoglycemia increases?
A. Ssk
B. Somatostatin
C. Gastrin✔✔
D. VIP
E. Secretin
88-Child with loose skin with easy bruising and defective procollagen 3.what can be the most striking
symptom / complication ?
A. Hyperextensible skin
B. Hypermobile joints
C. Problm in articular cartilage
D. Rupture of large vessels✔✔
89-Anterior pituitary tumor will compress?
A. optic nerve✔✔
B. occulomotor nerve
C. abducent nerve
D. trochlear nerve
E. trigeminal nerve
90-In a patient with a tumor in superior mediastinum compressing the superior vena cava, all of the
following veins would serve as alternate pathways for the blood to return to the right atrium,
EXCEPT:
A. Azygous vein
B. Hemiazygos vein
C. Internal thoracic vein✔✔
D. Vertebral venous plexus
E. Lumbar veins
91-Which of the following is anti cancer
A. chocolate
B. apple✔✔
C. cheese
D. Nitrated meat
E. Rum
92-in a study carotid chemoreceptor denervated in animals so which one is least effected.
A. PO2 arterial
B. PCO2 arterial✔✔
C. PO2 venous
D. H+ ion
E. HCO3 level
93-Patient presented with inability to write, read and speech, most likely lesion is in ?
A. Medulla
B. Frontal lobe
C. Temporal lobe
D. Parietal lobe
E. Both temporal and parietal✔✔
94-Histopathology report showing pleomorphism, rete ridges, loss of polarity and increased nuclear
to cytoplasmic ratio what is the dx?
A. Squamous cell CA
B. Verrucous CA✔✔
C. Sarcoma
D. None
95-Quatidian malaria is caused by ??
A. P Malaria
B. P falciparium✔✔
C. P ovale
D. P vivax
E. None
96-Tertian malaria is caused by ??
A. P Malaria
B. P falciparium
C. P ovale
D. P vivax ✔✔
E. None
97-Quartan malaria is caused by ??
A. P Malaria✔✔
B. P falciparium
C. P ovale
D. P vivax
E. None
👉Quotidian also called #malignant_tertian
98-The most probable cause of edema in cirrhosis of liver is
A. Hypoproteinemia
B. Increase in systolic bp
C. Inflammation of serosal layer
D. Portal hypertension✔✔
E. Sodium retention
99-Purkinje fibers are fastest in transmitting impulse because
A. They have wider diameter✔✔
B. They have large no of sodium channels
C. Intercalated junction
D. Gap junction
100-Serious adverse effects of valproate include:
A. Chronic pancreatitis
B. Fulminant hepatitis✔✔
C. Acute renal failure
D. Coagulation disorder
E. Mysthenic syndrome
101-Marker raised 60% in colon cancer n 80% in pancreatic cancer.
A. CEA
B. CA19-9✔✔
C. CA125
D. CA15-3
E. PSA
102-Patient having traveler’s diarrhea not responding too antidiarrheal drugs, which drug should be
given
A. Metronidazole
B. Erythromycin
C. Norfloxacin✔
D. Chloramphencol
103-Drug of choice in fluroquinpones resistant traveler’s diarrhea
A. Metronidazole
B. Azithromycin✔
C. Norfloxacin
D. Chloramphencol
104-Drug of choice for traveler's diarrhea
A. Bismuth subsalicylate✔ #1st best choice..
B. Loperamide #2nd best chocie ..
C. Antibiotic{ciprofloxacin>>norfloxacin} #third best
105-Drug of choice for MRSA
A. Fusidic acid✔✔
B. Metronidazole
C. Aztreonam
D. penicillin
E. Co amoxiclav
106-Most common predisposing factor for squamous cell carcinoma of skin.
A. Marjolin ulcer
B. Actinic keratosis
C. Bowen's disease✔✔
D. None
107-Common direction of Shoulder joint dislocation
A. Superior
B. Inferior
C. Anterior✔✔
D. Medial
E. Lateral
108-Common direction of humeral head dislocation
A. Superior
B. Inferior✔✔
C. Anterior
D. Medial
E. Lateral
109-A pregnant hyperthyroid lady, during her 5th month of pregnancy, which antithyroid drug shoud
be given?
A. propylthiouracil
B. Methimazole✔✔
C. Radioiodine
D. None
110-Negative charge of basement membrane is due to?
A. Elastin
B. laminin
C. Cadherin
D. Heparan sulphate ✔✔
E. Selectin
111-In case of reimplantation of an amputated digit, which of the following structures is fixed first?
A. Nerve
B. Artery
C. Vein
D. Bone✔✔
112-Shopkeeper suddenly collapsed with fine thready pulse of 120/min and low bp of 80/60 with
pale skin before collapsed he experienced sudden severe chest pain n epigastric pain reason of
collapse?
A. Cardiogenic shock
B. Pulmonary embolism✔✔
C. Gastritis
D. Dissecting aortic aneurysm
113. Shortest acting benzodiazepine
A. Alprazolam
B. Temazepam
C. Triazolam
D. Midazolam✔✔
114. Adrenal Medullary substance comprising of how much of Adrenal Gland.
A.80%.
B.50%.
C.28%.✔✔
D.90%.
E.10%.
115. Erythropoiesis is stimulated by?
A. Hypoxia
B. Anemia
C. Etythopoietin✔✔
D. Low blood volume
116. Erythropoietin is stimulated by?
A. Hypoxia✔✔
B. Anemia
C. Etythopoietin
D. Low blood volume
117. Human can survive without?? Or
Humans most easily tolerate a lack of which of the following nutrients?
A. Protein
B. Lipids
C. Carbohydrates ✔✔
D. Calcium
E. Iodine
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