Zytiga 250 mg

Zytiga is a type of classification belongs to antineoplastics

and it contain active ingredients of Abiraterone acetate.
Which is an antiandrogen medication is indicated for the
treatment of prostate cancer which spread to other parts of
the body.
Zytiga is also used along with prednisone, a steroid. In
clinical trials Zytiga is used for prostate cancer and
advanced breast cancer.
Usage
Zytiga is an inhibitor of CYP17 which is used to treats the
patients with metastatic castration-resistant prostate
cancer, The patient have received earlier chemotherapy
with docetaxel combination with prednisone and in failure
of androgen deprivation treatment.
The patient clinically not used for chemotherapy with
prednisone or prednisolone will preferred treatment with
metastatic CRPC in adult men.

Trade name :Zytiga

Active component : Abiraterone Acetate
Strength :250 mg
Manufactured by :Janssen Pharmaceuticals
Form :Tablets
Packing: 120 Tablets

Precautions
Do not take other medications, i.e prescription, over-the-
counter, vitamins, herbal remedies, etc be sure to inform
the doctors before the treatment. Aspirin do not
administering and products containing aspirin till doctor
particularily allow the drug.
• In women Abiraterone acetate is not currently used. if
administrating abiraterone acetate by woman, Do not get
pregnant and breastfeeding not recommended during
treatment
• Unknown process of abiraterone acetate is eliminated
in semen, hence do not use condom and another method
of birth control by men during treatment and for 1 week
following the last dose of abiraterone acetate.
Drug Interaction
• Effects of Abiraterone on drug metabolizing enzymes
Abiraterone is a hepatic drug-metabolizing inhibitor
CYP2D6, when substrates (dextromethorphan) of it is co
administrated with Abiraterone will increases the Cmax
and AUC dextromethorphan.
• Drugs that inhibits or induce CYP3A4
Abiraterone interaction with strong CYP3A4inhibitors or
inducers, the pharmacokinetics of Abiraterone is not
evaluated properily, so avoid or use with caution while
abiterone therapy.

Pregnancy
Category X: Abiraterone acetate is not recommended for
womens, It will cause fetal harm when administered to
pregnant women. During treatment if women become
pregnant, immediately stop the drug and give counseling
to the women.

Side Effects
Patients taking Abiraterone acetate have following side
effects are common in >30% occurring
• Retention of fluid
• Triglycerides increased
• Increased liver enzyme
Less common side effects of Abiraterone 10-29%
occurring:
• Joint discomfort
• Hypokalemia
• Swelling of hands/ feets
• Myalgia
• Hypophosphatemia
• UTI

Missed Dose
If missed a dose take have it as soon you remember, if
time for next dose reach, then leave the missed dose and
follow regular schedule. Do not take two dose at a time.
TAKE ADVICE FROM THE DOCTOR.
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Website : http://anti-cancer-drugs.com/zytiga-
250mg.php