SAVITRIBAI PHULE PUNE UNIVERSITY

(Estd. 1949)
Research and Innovation
@
Savitribai Phule Pune University

Prof. N. R. Karmalkar
(Vice Chancellor)
July 28, 2018
Savitribai Phule Pune University
ty is known for …..

Powerful Academics & Thought Leadership Infrastructure & Novel ResearchInitiatives

DRDP
Central Instrumentation Facility Start-Up Grant
Science Park Faculty R es ea rc h Projects
State of the Art Laboratories Travel Grants
e-Content Development Studio Ph.D. Stipends
10 t h In University
CGPA: 3.60 Smart C la s s room s P o s t Doc. Fellowships
18 t h Overall 601-800

International MOUs Fellows P a d m a Awardees Modern S p ort s Complex

S p ort s Scholarships
27 7 24 Yoga Education
R es ea rch Center
National Institutes on Campus &Industry Collaborations

University Footprint Socially Inclusive

Scholarships
Grants Solar-Thermal Plant
Earn & Learn S c h e m e P P P Model
Social Structure Thermax a s Industry Partner

Tribal Development
Affiliated Colleges : 968 R es ea rch Publications : 5251 Digital Dashboard
S t u d ent s Enrolled : 6.92 Lacs P a t en t s : 112 Analytics Engine
R es ea rch Center : 70 Disclosures/Copyrights : 31 Life-Long Learning
Industry Collaborations : 107 Technology Transfers :7
Community Radio
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Powerful Academics & Thought Leadership

Milestones… Strengths

Large number of active collaborations – National & International

Category – I Autonomous Status by UGC

University with Potential for Excellence UPE – Phase IIongoing

DST-PURSE(Category-I) Sponsored University -2014

Design Innovation Centre of MHRD - 2015

Selected for ‘GIAN Initiative’ by MHRD -2016

Implemented ‘Obama-Singh 21st Century Knowledge Initiatives’ –
2012
Hosting Research Institute of National Importance

Received Maharashtra ‘e-Governance Excellence Award - 2013’

Skill Development Centre on Campus : DDU-Kaushal Kendra byUGC

Novel Initiatives – Since1970s..

Strong Industry-University Partnerships

Academic Autonomy to Campus Departments (Early 1980)

Interdisciplinary and Multidisciplinary Programmes

Centres for focussed and emerging areas for advanced studies

Landmark Infrastructural Initiatives beginning early 80’s

Establishment of Self-financed Departments &Programmes

Established ‘International Centre’ – 10000 foreign students in 10 years

IT-based Processes in all functional areas

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Infrastructure & Research Initiatives

At a Glance Novel Research Initiatives

CCIH(Center for Complimentary & Integrative Health)-Rs. 4.5Cr

ESDM sanctioned by RUSA – Rs. 50 Cr

University Campus of 411 Acres with 49Departments

Sponsored Projects during last 5 years : Rs. 500 Cr

272 Programmes, 4709 Students

Creation of Central Instrumentation Facility – Rs. 50 Cr

Teachers : State Sanctioned 440, filled – 326

Creation of Virtual ClassRooms

Teachers from own resources - 150

Establishment of 20 Post-Doc Fellowships

UGC SAP Departments - 14, UGC CASDepartments - 8

Stipend for M.Phil. & Ph.D - Rs. 2 Cr

DST FIST Departments - 8

Departmental Research and Development Program – Rs. 4.25 Cr

Chair Professors – 19 , Distinguished Professors - 8

Seed Research Grant - Rs. 10 Cr

On Campus accommodation – 3000

Quality Improvement Program – Rs. 12Cr

Environmental Friendly Campus

Faculty Development Centre – Rs. 7.5 Cr

Established Science Park, ISRO-UoP Cell

Total Research Budget : 196.10 Cr Yearly

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Core Thematic Areas…
VISION SPECIFIC - Science & Technology for Sustainable Development

New & Novel Materials

HOLISTIC
 Materials for Energy Harvesting

Translational Research in health
 Materials for Rainbow solar cells

 Thin film flexible solar cells of women and children

 Dyesensitized Solar Cells

Determinants of health in
 Materials for Gas Storage
Maharashtra
 Supercapacitors for Energy storage

Biodiversity of Western Ghats

Biotechnology
 Nanobiotechnology

 Biotechnology for Therapeutic applications and Environmental solutions

Emerging Areas – Cognitive Sciences, Complex System

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 New Initiatives for strengthening Research and Innovation

SPPU Research Park

Technology Transfer Office

Innovation and Incubation Cell

Section-8 company forming an SPV (Special Purpose Vehicle)

Tinkering Laboratories and Hackathons

New 20 Post-docs
docs and Research Scientists

Centre for Industry Consultancy & Research

150 Patents in Next 15 Years with 5% Commercialization

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 Central Instrumentation Facility (CIF)

Sophisticated instruments for the benefit of stakeholders

Consultancy services to industries and institutions
a) Current Facility c) Facilities in Pipe Line

500 MHZ LCMS-MS FESEM-EDS CD PPMS

SCXRD Confocal Microscope GCMS-MS TEM LA-ICP-MS

b) Departmental Facility Users

Industries
14 %
Govt. Institutes
SPPU
15 %
55%
Other Universities
BET GC-2014 11 %
Breakdown
5%

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Potentiostat
Development of Accelerator Head Assembly for 6-20
6 MeV
Energy Electron and Proton Therapy (SPPU +SAMEER)
+SAMEER
Society for Applied Microwave Electronics Engineering & Research

6-18 MeV Linear Tech Development Experiment with ion

Accelerator beam

Gantry for Radiation

Therapy

Gantry for the Radiation Therapy made by 7

S.P. Pune University and SAMEER
 The Technology Firsts

India’s First
Solar-Biomass
Biomass Hybrid Power Plant

Linear Axis Remote pump operation using

Common Drive First IBR approved Solar Boiler mobile technology recognized
Parabolic system for power generation by
Trough DST/Lockheed Martin

Shive project’s other notable achievements…

Non
Non-evacuated receiver
tube technology Thermal Storage built-in

Pioneering serial Direct Steam Generation/

arrangement of turbines Recirculation
Indigenized Solar
Collector
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Description of Methodology: our Approach
Printed Electrodes and Digital Electronics
Compact Portable Easy-to-use
use Handheld Point-of–care-testing
Point
Sensor fabrication flow: Screen Protocol development for Wireless
Printing/inkjet printing network:
• Development of hardware, software,
Counter electrode: Carbon
to communicate data through
Reference electrode (Ag/AgCl):
Bluetooth and interface with Android
Working electrode
Ag/C leads

Substrate: Polydimethylsiloxane( PDMS)/ Polycarbonate (PC)/PET

Prototype Development
with Electronics
Interface Module

Our Patents: Photoimagable thick film

technology for Micro/Nano Photoconductor
• 1561/MUM/ 2010
• US patent no WO/2011/14511,
PCT/IN2011/000341, (2011).
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Air Plasma Torch for Municipal and E-Waste Management
at SPPU

Fabrication of small scale Air Plasma Gassifier unit at S P Pune University, Pune using
AIR plasma torch, 0-40 kW, 50-75 cm plasma plume and core temperature ~ 5000 K.

Plant will be capable of burning about 100 kg of Municipal Waste per day in about 6-7
hours using an air based modified torch at 30 kW input power at no greenhouse gas
footprint(< 20 ppm regulatory norms).

This plant will be sufficient to manage the MSW from the University.
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 High current density Cold Cathodes for table top
Accelerators and hand-held
hand X-ray tubes

 Synergetic utilization of ‘high aspect ratio’ due to array of 1D Si nanoneedles

Key points: and ‘low workfunction’ of Metal Hexaboride (GdB6, LaB6).
 Emission current density: ~ 50 mA/cm/cm2. (Operation in pulsed mode).
 Development of cold cathodes to meet the requirement of Accelerators and X-ray tubes.

Work Plan:  High aspect ratio’ array of 1D Si nanoneedles

Thermal evaporation of catalyst (Al/Sn
Sn)
Plasma Cleaning/processing
Hot Filament CVD

 Metal Hexaboride (GdB6,/LaB6) thin layer coating

Pulse Laser Deposition (PLD) or
E-beam deposition

 Field emission characterization

(Continuous and pulse mode)
 Development of prototype X-ray
 Testing of cathodes for Accelerator (at SAMEER)
(Continuous and pulse mode)

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Water oxidation catalyst

Turn over number = 879

b)

Figure 1 a)The water oxidation activity and kinetic profile (inset) and b) Pourbaix diagram of [Ru(bpg)(tpy)H2O]2+

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 Light-driven
driven Hydrogen Evolution from Water

Figure 2. a) The graphical abstract b) the H2 evolution and kinetic profile (inset) of CoII6L18 cage 13
Fuel Cell Membranes

Fig. 1 Hydrogen-bonded complex Fig. 2 Nyquist plot of proton conductivity Fig. 3 Reaction pathway obtained by climbing-image
Nudge Elastic Band (NEB) method

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 Center for Intelligent Systems (CIS)
(CIS

The intellectual merit of the CIS lies in:
 Developing new technologies for estimation of rapid deployment in
application environments, thus substantially enhancing the current state of
investigations and possibly opening new areas of critical innovations of
existing techniques.

The broader impacts of the proposed CIS are:

 Advancing the technology base for the analysis purpose, thus impacting
numerous fields of science and technology, social science, environment,
education, agriculture etc
 Leveraging research to undergraduate/graduate education through planned
microATM © CIS-SPPU
experiential learning activities in currently offered courses in engineering
and technology and blend them with current market trends thus making the
innovation base relevant to state-of- the-art.
 Towards promoting education of highly qualified students on the post-
graduate and doctoral level (Ph.D. and Master’s)
 Developing interactive web-based course material that will be
introduced at the host institutions and will be disseminated publicly for
use by others

First product which emerged out of CIS: MicroATM

 This is miniature version of ATM with biometric based personal
authentication. The machine is linked with AADHAR and has compliance
as per the specifications mentioned on UIDAI web- portal (e.g. ISO
19794-2). The device has elegant looks and compact form and looks as
follows

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 1.Biotherapeutics
Iminosugars as Glycosidase Inhibitors
Diabetes and obesity
Lead Human pancreatic amylase inhibitors
Diazaspiro
Diazaspiro-iminosugars and polyhydroxylated spiro-bislactams

from Curcuma, Azaridactha and Dioscorea

RSC Adv (2015)

Hydroxyethyl piperidine iminosugar and N-alkylated derivatives
γ-Hydroxyethyl

Bioorg Med Chem (2014)

PLoS ONE (2014), (2015)

The Nat Prod J (2013)
Food Chem (2013)
Biological activity of Psoralen from Psoralea corylifolia as
anti-cancer
cancer agent
Docked complex with DNA topoisomerase I

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 Anti-microbial
microbial Agents

Peptides
Glycolipids
Nanoparticles

Effective against human and aquaculture pathogens biofilms by Bacillus licheniformis

Microbial Pathogenesis (2017)
Aquaculture Res (2016)
PloS one (2013)
Antibiofilm activity of Au-AgNPs
Au from Plumbago zeylanica
J of Nanobiotech (2013)

Biofilm Disruption by 17
A. calcoaceticus PUCM Int J Nanomed (2014)
 2.. Industrial Biotechnology
GHs, etc.
Enz

Microbial biodiesel production from Carbohydrate bioengineering

Bacterial cell
Link er

sugarcane bagasse and waste cooking oil Linker

Enzyme-linked gene clusters on the

Enzyme
Cellulosome assembly of bacteria
Lignocellulosic wastes

Higher biomass production

Bioenergy/Biofuels/Platform
chemicals
&
Potential for Power Generation etc.

Chimeric dockerin attached

to different enzyme modules

Enz

Doc A B

CBM CBM

Energy (2018) Designer Cellulosomes

2. Industrial Biotechnology
Microb. Cell Factories(2017)
Bioresource Technology(2015)
Bioenergy Research(2015)
.

Biosurfactants
Bioemulsifiers

Conversion efficiency of Self-

Self-assembling
microbial biomass to biodiesel protein as 18
Biomaterial
 3.. Plant and agricultural biotechnology
Biotic and abiotic stress biology
Plant insect interactions

Insect Biochemistry & Biotechnology

Medicinal Plant Biotechnology

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Engineering pathways for useful metabolites from plants
 4.Biotechnology for Human Health
Immune-modulation

Tumour model
Novel Epoxide hydrolase from

Angiogenesis
Yarrowia lipolytica for

Metastasis
enantiselective conversion of
benzylglycidyl ethers

Sci. Reports, 2017)

RSC Adv, 2018 Physiological stress
Sci Reports, 2017 3-D tumor models
Stem Osteogen
Cell esis Yeast model of cohesinopathy

Single spot is normal

Chondroge
Adipogenes Stem cell model cohesion
nsis Multiple spot is defective
isis Gingival calvarial cohesion
tissue- defect/intervertebral
intervertebral
derived disc space injury
Ovarectomized MSCs
mouse model
Synthesis and model
characterization of
nanoparticles
Anabo Nanoparticle
lic
drugs
Stem cells in Loading of anabolic

Regenerative drug on nanoparticle

Synergistic bone

medicine Synergistic enhancement in

matrix proteins
anabolic effect???

Mechanism underlying in the 20

and mineralization ??? Anabolic drug loaded interaction of osteoclast
nanoparticle and osteoblast in presence
of anabolic drugs ?????
 Identification of a novel role for
Glucosamine in drought tolerance
Highlights
novel role for
Glucosamine as a
desiccation stress-
stress
responsive metabolite
in the Indian tropical
aquatic midge,
Chironomus ramosus.
ramosus

Significance
valuable addition to
the list of stress-
stress
management
strategies to potentiate
recovery post
desiccation through
recruitment of
1Stress Biology Research Laboratory, Department of Glucosamine.
Zoology
Ongoing work
Savitribai Phule Pune University, Pune-411007, INDIA. assessment of
Correspondence and requests for materials should be
extended benefits of
addressed to B.B.N. (email: bbnath@gmail.com)
Glucosamine in
translational research
to devise patentable
technology for
mitigation of adverse
consequences of
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global warming.
 Innovation : Social Sciences and Humanities

Robust and long standing traditions of research in the fields of

Maharashtra studies, Election studies, Urban studies, translations
studies, Media studies

Only Indian University to systematically map the Diversity of its student

profile (under the Obama Singh Knowledge Initiative)

Only Indian University to participate in ‘Euroculture’
‘ program of the EU

Digitization and documentation of regional resources

Interdisciplinary teaching programs in the fields of Women’s Studies,
Defense and Strategic Studies, Education, Media Studies, Languages

Active engagement of the faculty in public domain

Partnerships with civil society organizations, government agencies and
industry in framing and implementation of academic programs

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