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STS: FINAL EXAM REVIEWER • Dreams are often broken when reality strikes.
SOURCES OF MEANING FOR THE GOOD LIFE THE PERMA MODEL: Scientific Theory of
• Wong’s implicit theory research Happiness
• Achievement, religion/spirituality, positive • Positive emotions – Feeling good
affect, relationships, self-transcendence, • Engagement – Finding flow
intimacy, self-acceptance, fair treatment. • Relationships – Authentic connections
• Basic needs for mental health and • Meaning – Purposeful existence
flourishing. • Achievement – Sense of accomplishment
THE HAPPINESS PURSUIT Aristotle: Some people may pursue things that are
• Everybody wants more happiness and good for themselves
success
• It’s good to know how to optimize happiness
and success ADVANTAGES OF THE MEANING PURSUIT
• There are many happiness coaches and • Avoids the pitfalls of self-centered pursuit of
self-help books on the market happiness and success.
• Sustains us between the highs of inspiration
RISK FACTORS and the lows of despair.
• The happiness pursuit becomes one’s • Happiness and flourishing will sneak in
ultimate purpose in life through the back door.
• Happiness is not guided by a philosophy of • Ability to transform adversities into
life informed by general principle of opportunities for personal growth.
spirituality, and virtue (e.g. Golden Rule)
THE GOOD LIFE IS A VIRTUOUS LIFE
THE GOLDEN RULES • A meaningful, authentic good life is based on
inner goodness.
• CONFUCIUS: What you do not want done to • “The end of life is eudaimonia.”—Aristotle
yourself, do not do to others • Eudaimonia means well-being, virtue and
• ARISTOTLE: We should behave to others human flourishing.
as we wish others to behave to us. • To live the good life is to become what we
• BUDDHISM: Hurt not others with that which ought to be as human beings—moral agents
pains thyself. who strive for moral excellence.
• CHRISTIANITY: Do unto others as you
would have them do unto you. ACCORDING TO ARISTOTLE
• His moral theory is teleological.
THE AMERICAN NIGHTMARE • Aristotle’s virtue ethics.
• The pursuit of this good life has ended in • The golden mean to avoid extremes.
misery and self-destruction for many people. • Practical wisdom: the proper end to our
• Examples: Kurt Cobain, Gwendolyn actions and the proper means to our end.
Hallsmith, Amy Winehouse, Lindsay • Four cardinal virtues: prudence, justice,
Lohan fortitude, and temperance.
IMPORTANCE OF BIODIVERSITY
- Famous for heirloom rice grown on the
1. Ethical
spectacular terraces of the Cordillera mountains
- “Every form of life is unique, warranting respect
of northern Luzon, the Philippines has become
regardless of its worth to man and to accord
a hotbed for protests over the development of
other organisms such recognition, man must be
genetically modified Golden Rice.
guided by a moral code of action.” - World
Charter for Nature – UN General Assembly
- Heralded on the cover of Time magazine in
2000 as a genetically modified (GMO) crop with
2. Agriculture/Food source
the potential to save millions of lives in the Third
- 75% of human nutrition w/ rice, maize, potato
World, Golden Rice is still years away from field
- about 20% of protein requirements of man
introduction and even then, may fall short of
- only 5000 of 75000 edible plant species have
lofty health benefits still cited regularly by GMO
been used by man for food
advocates, suggests a new study from
- Tropical plants: almost 200 species with 3000
Washington University in St. Louis.
still available
- crop diversity
- GMO advocates have long touted the
- Rice grassy stunt virus (RGSV)
innovation as a practical way to provide poor
- South and Southeast Asia, China, Japan,
farmers in remote areas with a subsistence
and Taiwan
crop capable of adding much-needed Vitamin A
- Philippines –1973 to 1977 and again from
to local diets. A problem in many poor countries
1982 to 1983
in the Global South, Vitamin A deficiencies
leave millions at high risk for infection, diseases - transmitted by brown plant hoppers
and other maladies, such as blindness. - 6,273 varieties were tested for resistance,
only one was resistant
- GMO proponents often claim that
environmental groups such as Greenpeace 3. Medicine and Pharmaceutical
should be blamed for slowing the introduction of - 1% tropical plants for medical use
Golden Rice and thus, prolonging the misery of - Southeast Asian traditional healers use
poor people who suffer from Vitamin A 6500 plant species as medicines
deficiencies - 80% of people from Third World rely on
traditional medicines
Status of Philippine Biodiversity - at least 68 common plants in the
What is Biodiversity? Philippines being used as medicines
- contraction of "biological diversity" - 3000 plants (70% in tropical rainforests)
- made popular by E.O. Wilson in his book identified by US National Cancer Institute
BioDiversity (1986) as having anti-cancer properties
- “Found wherever there is life, be it in the - 500 marine species with anti-cancer
cities, countryside, backyard, homes.” activity
Law of Inheritance
- In the majority of cases, one normal gene is
sufficient to avoid all the symptoms of disease.
- If the potentially harmful gene is recessive, then
its normal counterpart will carry out all the tasks
assigned to both.
- Only if we inherit from our parents two copies of
the same recessive gene will a disease
develop.
ED1B
What is Gene Therapy Goal of Gene therapy
- Gene therapy is the insertion of genes into an - A normal gene may be inserted into a non-
individual's cells and tissues to treat a disease, specific location within the genome to replace a
such as a hereditary disease in which a non-functional gene. This approach is most
deleterious mutant allele is replaced with a common.
functional one. - An abnormal gene could be swapped for a
- Although the technology is still in its infancy, it normal gene through homologous
has been used with some success. recombination.
- The abnormal gene could be repaired through
How It Works selective reverse mutation, which returns the
- A vector delivers the therapeutic gene into a gene to its normal function.
patient’s target cell - The regulation (the degree to which a gene is
- The target cells become infected with the viral turned on or off) of a particular gene could be
vector altered.
- The vector’s genetic material is inserted into
the target cell Delivering desired Genes
- Functional proteins are created from the
therapeutic gene causing the cell to return to a
normal state
A success story
- As of early 2007, she was still in good health,
and she was attending college.
- Some would state that the study is of great
importance despite its indefinite results, if only
because it demonstrated that gene therapy 1. PRECESSION – the change of the orientation
could be practically attempted without adverse of the rotational axis of the Earth
consequences.
2. EQUINOXES –two days in the year when the
Safety Northern and Southern Hemispheres receives
- Although viral vectors are occasionally created equal amount of sunlight
from pathogenic viruses, they are modified in • Spring equinox (March 20 or 21)
such a way as to minimize the risk of handling • Autumnal equinox (September 22 or 23)
them.
3. SOLSTICES – either of the two moments in the
What are the ethical issues surrounding gene year when the Sun’s apparent path is farthest
therapy? north or south from Earth’s Equator
- How can “good” and “bad” uses of gene therapy • Summer solstice (June 20 or 21) –
be distinguished? occurs when the sun is directly over the
- Who decides which traits are normal and which Tropic of Cancer, which is located at
constitute a disability or disorder? 23.5°latitude; marks the longest day and
- Will the high costs of gene therapy make it shortest night of the year
available only to the wealthy?
- Could the widespread use of gene therapy • Winter solstice (December 21 or 22) –
make society less accepting of people who are occurs when the sun is directly over the
different? Tropic of Capricorn, which is located at
- Should people be allowed to use gene therapy 23.5°south; marks the shortest day and
to enhance basic human traits such as height, longest night of the year
intelligence, or athletic ability?
Climate Models
- Climate affected by:
Climate Change Terminologies •winds, clouds, ocean currents, and albedo
- Used to explore past climate events
1. GREENHOUSE GAS - Advanced models can project future warming
- Gas that absorbs infrared radiation events
- Ex: Carbon dioxide, methane, nitrous oxide, - Models are only as good as the data and law
chlorofluorocarbons and tropospheric ozone used to program them
•They have limitations
2. POSITIVE FEEDBACK
- Change in some condition triggers a response Effects of Global Climate Change
that intensifies the changed condition - Ocean as CO2sink -excess CO2is starting to
harm ocean life
3. INFRARED RADIATION
- Radiation that has a wavelength that is longer Effects of Global Climate Change-Melting Ice
than that of visible light, but shorter than that of and Rising Sea Levels
radio waves - Sea level rise caused in 2 ways
•Thermal Expansion
4. GREENHOUSE EFFECT •Water expands as it warms
- Increase of heat in a system where energy •Melting of land ice
enters (often as light), is absorbed as heat, and •Retreat of glacier & thinning of ice at poles
released sometime later - Melting has positive feedback
•Increased melting decreases ice, which
Climate Change: Evidence for Climate Change decreases albedo leading to further
- 11 of the 12 years between 1995 and 2006 warming
were among the twelve warmest years since
the mid-1800s Case-In-Point Impacts in Fragile Areas
- PHENOLOGICAL SPRING in N. hemisphere - Eskimo Inuit live traditional life dictated by
now comes 6 days earlier freezing climate
- Warming is not due to natural causes - Climate change is altering their existence
Human produced greenhouse gases are •Wildlife are smaller or displaced
most plausible explanation •Reduced snow cover and shorter river ice
seasons
Causes •Thawing of permafrost (right)
- Greenhouse gas concentrations increasing
- Increased concentration of CO2(right)
•Burning fossil fuels in cars, industry
ED1B
Effects of Global Climate Change-Changing Dealing with Global Climate Change-
Precipitation Patterns Relationship Between Mitigation and
- Some areas will get more water, some areas Adaptation
will have greater droughts
•Ex: Hurricanes will likely get stronger
Effects on Agriculture
- Difficult to anticipate
•Productivity will increase in some areas
and decrease in others
- Rise in sea level will inundate flood plains and
river valleys (lush farmland)
- Effect on pests is unknown
- Warmer temperatures will decrease soil
moisture-requiring more irrigation
- Location (i.e. elevation and altitude) where
certain crops can be grown may have to
change