Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
Explanations:
- the total number of Qs is different than in the original file, because I don’t like repeated Qs, so I was removing
some while editing
- the numbering system is different than in the original file, because I wanted to fit some pictures on a certain
page and due to that I had to move around some Qs, so Qs #123 in this file might be #150 in the original file:
I was regretting that step while studying with other people, but there’s nothing I can do now
- usually the Qs in this file compared to the original are within +/- 20 Qs range, so if you are discussing a Qs with
someone else look for it on a certain page, page up & page down = you will find it
- this file is a combination between two SJ files available on the group (forgot which ones), if there was a
difference in an answer I would look it up and post an explanation
- I edited a lot of answers while studying with others, I believe these answers are correct and have minor
mistakes
- I passed studying from this file
- questions with “????” → I didn’t understand the qs and I am not sure of the answer
MC = most common
Epi = epinephrine
NEpi = norepinephrine
LN = lymp node
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1. Papilla of the tongue, no taste: FILIFORM
3. Gustatory of the anterior 2/3 will travel along: CHORDA TYMPANI TRAVELS ALONG LINGUAL NERVE
4. Hamulus from which bone: MEDIAL PTERYGOID PLATE (SPHENOID)
5. Which muscle inserted to coronoid: TEMPORALIS
6. Lung innervation: T2-T4 (S NS), VAGUS (PS NS)
7. Burning sensations of the mouth, which fibers transmit it: C FIBERS
8. Facial paralysis after anesthesia: FACIAL NERVE PARALYSIS (PAROTID GLAND)
9. Which nerve travels with external jugular vein: GREAT AURICULAR
10. Nerve that innervates muscles below the true vocal cord: INFERIOR LARYNGEAL (RECURRENT LARYNGEAL)
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11. What cause supination between ulna & radial: BICEPS BRACHII
Structures passing over parotid: facial n., ECA, auriculotemporal n., retromandibular v., superficial temporal v.
Mneumonic: FEARS
Great auricular n. (C2-C3) innervates skin over parotid gland – passes posteriorly.
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13. Choose two visceral arteries branches of abdominal aorta.
Abdominal aorta:
- 3 anterior visceral branches coeliac, SMA, IMA
- 3 paired lateral visceral branches suprarenal, renal, gonadal
- 5 paired lateral abdominal wall branches inferior phrenic, 4 x lumbar
- 3 terminal branches 2 x common iliac, median sacral
21. Too much clenching, abuse activation of: MASSETER (or temporalis)
22. Vitamin C is important for: COLLAGEN SYNTHESIS (hydroxylation of proline and lysine)
23. Enamel is harder than bone due to: HIGHER INORGANIC CONTENT / BIGGER CRYSTALS
24. ATP needed for all except: PENTOSE PHOSPHATE PATHWAY / HMP SHUNT
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26. Muscle contraction causes shortening of: H ZONE & I BAND
Mineralocorticoid: aldosterone
Androgens: testosterone, DHT, androstenedione, DHEA
Cariogenic bacteria synthesize glucans (dextrans) and fructans (levans) from their metabolism of dietary sucrose (via
glucosyltransferase), which contribute to their adherence to tooth surfaces. As a consequence, lactic acid is formed, reducing salivary
pH and creating sites of enamel demineralization and cavitation.
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35. Which virus is non latent: POLIO & RHINO
36. Where does the vertebral artery enter the skull: FORAMEN MAGNUM
Structures passing through foramen magnum: Spinal Meninges Make A Special Vertical Sheath
Spinal cord, Meninges, Meningeal lymphatics, Accessory n., Sympathetic plexus, Vertebral a., Spinal branches of vertebral a.
37. Which define the mouth size: THE DEGREE OF FUSION BETWEEN MAXILLARY AND MANDIBULAR PROCESS
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61. Paralysis of the face muscles below zygoma: UMN DAMAGE
UMN damage: paralysis on contralateral side of the lower quadrant of the face only
LMN damage: paralysis on ipsilateral side for the upper and lower quadrants of the face
62. As the patient ages, the arteries loose elasticity – what will happen to the pulse pressure: SYSTOLIC, OR NO CHANGE
DIASTOLIC, PP, CONTINOUS FLOW IN THE CAPILLARIES WOULD CHANGE INTO A PULSATILE FLOW
63. Pulmonary arteries and aorta are alike because: TRICUSPID SEMILUNAR VALVE, AMOUNT OF BLOOD FLOWING IS THE SAME
64. Primary mandibular incisor: STRAIGHT INCISAL EDGE, NO MAMELONS, SMALLEST F-L DIMENSION OF ALL PRIMARY TEETH
65. Why haptens can’t elicit the formation of an antibody: TOO SMALL, THEY NEED A CARRIER
Modifies saliva form isotonic to hypotonic. Striations are related to a combination of foldings of basal cell MBs & radially arranged
mitochondria for electrolyte & water transport. Simple, low, columnar epithelium.
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69. Excessive ACTH will cause: CUSHING’S DISEASE; HYPERGLYCEMIA AND WEIGHT GAIN
Functional groups:
Cerebroside → glucose
Sphingomyelin → choline
Ganglioside → a lot of sugars
Ceramide → hydrogen
86. Virus that causes chickenpox can also cause: SHINGELS/HERPES ZOSTER
87. Patient with diabetes t. I should watch 3 of the following: CARBOHYDRATES, FAT, TOTAL CALORIES
88. Leukoplakia, what type of epithelium: PARAKERATOSIS / ORTHOKERATOSIS = HYPERKERATOSIS (can develop into SCC)
89. Decreased water permeability in distal tubule: ALDOSTERONE
90. Cell not found in a purulent secrection: PLASMA CELLS
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91. ATPase binds to: MYOSIN
92. Promote osteogenesis: SOMATOMEDIN
The steeper the articular eminence, the longer the posterior cusps.
ACTH stimulates secretion of cortisol – it is a steroid, glucocorticoid hormone. When used as a medication, it is known as hydrocortisone.
It is produced by the zona fasciculata of the adrenal cortex. It is released in response to stress and low blood-glucose concentration. It
functions to increase blood sugar through gluconeogenesis, to suppress the immune system, and to aid in the metabolism of fat,
protein, and carbohydrates. It also decreases bone formation.
100. From otic ganglion to the parotid gland: SECRETOMOTOR POST GANGLIONIC PARASYPATHETIC FIBERS (that travel along the
auriculotemporal branch from CN V3 to the parotid gland)
101. Which part of the nephron uses the most ATP: PCT
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102. From splanchnic to celiac trunk: PRESYNAPTIC SYMPATHETIC
103. Over contouring of the lingual surface of anterior teeth will? DECREASE OVERJET
104. Pain from teeth to: PARIETAL LOBE, NUCLEUS INTERPOLARIS
105. What separates diencephalon: 3rd VERNTRICLE
106. How increasing anterior overbite will affect the height of posterior cusps? MAKE THEM TALLER/HIGHER
107. Patient was exhibiting a mutually protected occlusion on her L side, then the MX canine was removed. The patient would exhibit:
GROUP FUNCTION
108. All of the following are the characteristics of a mutually protected occlusion, except: POSTERIOR CONTACT DURING LATERAL
MOVEMENT
Found online:
Each of the following is a condition usually found in a mutually protected occlusion, in the normal upright position, except one. Which
one is this exception?
A) None of the posterior teeth contact on the non-working side when the mandible moves laterally
B) Anterior teeth disclude all posterior teeth in protrusive movement.
C) Condyles are in their most supero-anterior position in closure.
D) Anterior teeth contact more heavily than the posterior teeth.
E) Axial loading of occlusal forces occurs in closure.
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114. Sensory (pain) innervation from the buccal vestibule of the mouth: LONG BUCCAL NERVE (V3)
115. Which triangle is bounded by superior belly of omohyoid, anterior borders of SCM & posterior belly of digastric: CAROTID
116. Abdominal aorta branches: CELIAC, SUPERIOR & INFERIOR MESENTERIC (compare #13)
117. Portal drainage from: SMALL AND LARGE INTESTINE
118. Vertebral artery enters the skull via: FORAMEN MAGNUM
120. Parkinson’s disease and Alzheimer’s disease, what they have in common: DEMENTIA
121. Calcitonin: INHIBITS BONE RESORPTION
122. Enamel pearl: HERTWIG’S REMNANT
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123. Myasthenia gravis, defect in: MYONEURAL JUNCTION
Myasthenia gravis (MG) is a long-term autoimmune neuromuscular disease that leads to varying degrees of skeletal muscle weakness
(attacks Ach receptors). The most commonly affected muscles are those of the eyes, face, and swallowing. It can result in double vision,
drooping eyelids, trouble talking, and trouble walking. Onset can be sudden. Those affected often have a large thymus gland or develop
a thymoma. Often improves with rest & worsens with activity. IT IS NOT A CNS DEGENERATION.
A Sertoli cell is a "nurse" cell of the testicles that is part of a seminiferous tubule and helps in the process of spermatogenesis; that is,
the production of sperm. It is activated by follicle-stimulating hormone (FSH) secreted by the adenohypophysis and has FSH receptor
on its membranes. It is specifically located in the convoluted seminiferous tubules (since this is the only place in the testes where the
spermatozoa are produced).
A granulosa cell or follicular cell is a somatic cell of the sex cord that is closely associated with the developing female gamete (called
an oocyte or egg) in the ovary of mammals.
148. Cilia move cerebral fluid from subarachnoid space to: VEINS
149. Supinator of the arm: BICEPS BRACHII (#11)
150. Not the effect of sympathetic nervous system: PUPIL CONSTRICTION
151. To reach submandibular gland duct you will have to: CUT THROUGH MUCOUS MEMBRANE ONLY
152. Infection at the corner of the mouth spreads to: SUBMANDIBULAR LYMPH NODES
153. Most superior part of the larynx: EPIGLOTTIS / ARYEPIGLOTTIC FOLD
154. Greater cornu of hyoid and CN IX (glossopharyngeal) arise from: 3rd ARCH
155. External auditory meatus: 1st CLEFT
156. Graft rejection: TYPE IV HYPERSENSITIVITY REACTION
157. All premolars have DMCR longer than MMCR except: MX 1st PM
158. Morphodifferentiation determines: SHAPE OF THE TOOTH
159. DEJ forms at: BELL STAGE
160. What occurs first: ELONGATION OF IEE
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164. Protection against occlusal forces: OBLIQUE FIBERS
165. acid phosphatase: PROSTATIC CANCER ( alkaline phosphatase – Paget’s)
166. Exotoxin with 3 factors: ANTHRAX (lethal factor, edema factor, protective antigen)
167. Ansa cervicalis innervates: INFRAHYOID MUSCLES
The ansa cervicalis is a loop of nerves that are part of the cervical plexus. It lies superficial to the IJV in the carotid triangle. Branches
from the ansa cervicalis innervate most of the infrahyoid muscles, including the sternothyroid muscle, sternohyoid muscle, and the
omohyoid muscle. Note that the thyrohyoid muscle, which is also an infrahyoid muscle, is innervated by C1 via the hypoglossal nerve.
In addition, the ansa cervicalis does not innervate the stylohyoid muscle, which is innervated by the facial nerve.
168. Why antibiotics give relief in peptic ulcer disease: ELIMINATE H. PYLORI, ACID SECRETION (PROTON PUMP INHIBITORS)
169. Which nerve to cut to treat peptic ulcer: VAGUS
The vagus nerves play a central role in regulating gastric acid production. Vagotomy performed in conjunction with either pyloroplasty
or antrectomy was once the gold standard for the treatment of peptic ulcer disease. The following decades saw the development of
histamine H2-receptor antagonists and proton pump inhibitors, along with the discovery of the role Helicobacter pylori plays in peptic
ulcer disease. The success of these modern nonsurgical therapies reduced the incidence of ulcer-related complications requiring surgical
interventions. When surgical interventions are required, technological advances have allowed vagotomy to be performed with
minimally invasive techniques with fewer procedure-related complications.
Trichophyton is a genus of fungi, which includes the parasitic varieties that cause tinea, including athlete's foot, ringworm, jock itch,
and similar infections of the nail, beard, skin and scalp. Trichophyton fungi are molds characterized by the development of both smooth-
walled macro- and microconidia.
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174. Activation of an enzyme include: PHOSPHORYLATION OF SERINE RESIDUE (PROKARYOTES) OR HYDROLYSIS OF A PEPTIDE UNIT
(EUKARYOTES)
175. Afferent of Breuer reflex of the lung: STRETCH RECEPTORS, CARRIED BY VAGUS NERVE TO PREVENT OVER-INFLATION
The Hering–Breuer inflation reflex is a reflex triggered to prevent over-inflation of the lung. Pulmonary stretch receptors present in the
smooth muscle of the airways respond to excessive stretching of the lung during large inspirations.
Once activated, they send action potentials through large myelinated fibers of the vagus nerve to the inspiratory area in the medulla
and apneustic center of the pons. In response, the inspiratory area is inhibited directly and the apneustic center is inhibited from
activating the inspiratory area. This inhibits inspiration, allowing expiration to occur.
The Hering–Breuer deflation reflex serves to shorten exhalation proprioceptors activated by lung deflation. Like the inflation reflex,
impulses from these receptors when the lung is deflated. It is initiated either by stimulation of stretch receptors or stimulation of travel
afferently via the vagus. Unlike the inflation reflex, the afferents terminate on inspiratory centers rather than the pontine apneustic
center. These reflexes appear to play a more minor role in humans than in non-human mammals.
Tyrosine kinase receptor adds phosphate group to tyrosine in a cell. Phosphorylated proteins have greater affinity for
GLUT-4 → glucose uptake from blood to tissues.
178. Rickettsia and viruses: OBLIGATE INTRACELLULAR (difference: rickettsia has both DNA & RNA)
179. Articulating surfaces in a newborn are covered by: HYALINE CARTILAGE
180. Infection in the posterior wall of maxillary sinus will spread to: ETHMOIDAL SINUS
181. Cytochrome p450: BIOTRANSFORMATION OF DRUG EFFECTS, INNER MEMBRANE OF MITOCHONDRIA, DETOXIFICATION, IN
PERICENTRAL VEIN ZONE IN THE LIVER
182. Na+ / K+ is an example of: ION CHANNEL – PRIMARY ACTIVE TRANSPORT
183. Fungal agar: SABOURAUD AGAR (also for bacteria → Nocardia)
184. Anti-A and anti-B both agglutinate: AB type
185. Not in liquid necrosis and inflammation: CELL AUTOLYSIS
186. Bonds between DNA units: PHOSPHODIESTER
187. Bonds between GAGs: GLYCOSIDIC
188. Maxillary molar infection will spread to: INFRATEMPORAL FOSSA,
MAXILLARY SINUS & BUCCAL SPACE
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189. Howship lacunae: OSTEOCLASTS (BONY REMODELING)
Osteoclasts occupy small depressions on the bone’s surface, called Howship lacunae; the lacunae are thought to be caused by erosion
of the bone by the osteoclasts’ enzymes. Osteoclasts are formed by the fusion of many cells derived from circulating monocytes in the
blood. These in turn are derived from the bone marrow.
Once glycolysis takes place in the cells cytoplasm it produces pyruvate, which continues on and into the matrix of the mitochondria.
The Krebs cycle is the next step of cellular respiration, but before the Krebs cycle takes place we need another step called Oxidative
Decarboxylation which has to convert pyruvate into acetyl-CoA.
The following steps occur:
1. A carboxyl group is removed as CO2. This is the decarboxylation part.
2. Then the remaining 2-carbon part is oxidized by NAD+. The NAD+ gains two hydrogen’s and the remaining two-carbon compound
becomes an acetic acid.
3. Then a coenzyme A (CoA) attaches to the acetic acid part forming acetyl-CoA. This is the molecule that is needed to continue in the
Krebs Cycle.
RMSF is a bacterial disease (RICKETTSIA) spread through an infected tick. Most people who get sick with RMSF will have a fever,
headache, and rash. RMSF can be deadly if not treated early with the right antibiotic.
Lyme disease = borreliosis (BORRELIA).
192. MD dimension of MX canine pulp canal: WIDEST NEAR THE CERVICAL 1/3
193. Mechanoreceptors in PDL varying in: THRESHOLD
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194. Produces secretin: S CELLS (DUODENUM)
Secretin is a hormone that regulates water homeostasis throughout the body and influences the environment of the duodenum by
regulating secretions in the stomach, pancreas, liver. It is a peptide encoded by the SCT gene.
195. All cause atrophy in the muscles except: EXCESSIVE HORMONAL STIMULATION
196. Gamma fibers: INTRAFUSAL FIBERS, INNERVATE MUSCLE SPINDLE, MAINTAIN MUSCLE TONE
Gamma motor neuron is a type of LMN that takes part in the process of muscle contraction, and represents about 30% of fibers going
to the muscle. Like alpha motor neurons, their cell bodies are located in the anterior grey column of the spinal cord. They receive input
from the reticular formation of the pons in the brainstem.
Although muscles can be in a relaxed state, muscles have a general resting level of tension. This is termed muscle tone and is maintained
by the motor neurons innervating the muscle. Its purpose is to maintain posture and assist in quicker movements, since if muscles were
completely loose, then more neuronal firing would need to take place.
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions
are mediated by histamine receptors H1, H2, H3 and H4. The histamine receptor H2 belongs to the rhodopsin-like family of G protein-
coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility
and intestinal secretion and is thought to be involved in regulating cell growth and differentiation.
Interferons (IFNs) are a group of signaling proteins made and released by host cells in response to the presence of several pathogens,
such as viruses, bacteria, parasites, and also tumor cells. In a typical scenario, a virus-infected cell will release interferons causing
nearby cells to heighten their anti-viral defenses. IFNs belong to the large class of proteins known as cytokines, molecules used for
communication between cells to trigger the protective defenses of the immune system that help eradicate pathogens. Interferons are
named for their ability to "interfere" with viral replication by protecting cells from virus infections.
Pick aspartate & carbamoyl phosphate (it has ammonia built in it: NH4 + CO2 → carbamoyl
phosphate) if the questions says “direct sources of ammonia in the urea cycle”.
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212. What regulates glycolysis: PFK
213. Transduction include all of the following except: CELL TO CELL CONTACT
Dystrophic calcification is the calcification occurring in degenerated or necrotic tissue. This occurs as a reaction to tissue damage,
including as a consequence of medical device implantation. Dystrophic calcification can occur even if the amount of calcium in the
blood is not elevated.
Metastatic calcification is deposition of calcium salts in otherwise normal tissue, because of elevated serum levels of calcium, as seen
in hyperparathyroidism.
These differences in pathology also mean that metastatic calcification is often found in many tissues, whereas dystrophic calcification
is localized. Metastatic calcification can occur widely throughout the body but principally affects the interstitial tissues of the
vasculature, kidneys, lungs, and gastric mucosa. For the latter three, acid secretions or rapid changes in pH levels contribute to the
formation of salts.
Asthma, COPD, emphysema, cardiac arrest, acute pulmonary edema are some of the causes.
In acidosis: Extra H+ goes into the cell and potassium leaves the cell which causes transient hyperkalemia.
In alkalosis: H+ leaves the cell and potassium enters the cell leading to transient hypokalemia.
Suicide inhibition (suicide inactivation or mechanism-based inhibition) is an irreversible form of enzyme inhibition that occurs when an
enzyme binds a substrate analogue and forms an irreversible complex with it through a covalent bond. The inhibitor binds to the active
site where it is modified by the enzyme to produce a reactive group that reacts irreversibly to form a stable inhibitor-enzyme complex.
Examples: aspirin, clavulanic acid, fluorouracil, penicillin, sublactam, allopurinol, AZT, exemestane
Thymydylate synthatase is an important enzyme, which inhibition is used in cancer treatment.
There are 3 major steps involved in the PCR technique: Denaturation, Annealing, and Extension (in sequence).
A Nissl body (Nissl substance) is a large granular body found in neurons. These granules are of rough endoplasmic reticulum (RER) with
rosettes of free ribosomes and are the site of protein synthesis.
Polio attacks Nissl bodies.
227. Urticaria (rash, hives) in penicillin allergy, which type of hypersensitivity: TYPE I
228. Clindamycin: BINDS TO 50S RIBOSOMAL SUBUNIT
229. Aminoglycoside: BINDS TO 30S RIBOSOMAL SUBUNIT
230. Long onset – long effect: estrogen, oxytocin, ADH, PTH, GH (???)
231. Slow onset – long effect: ESTROGEN (???; long acting effect = estrogen, GH not in option)
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232. Buccinator: PENETRATED IN INFERIOR MANDIBULAR NERVE BLOCK
233. The relation between lingual nerve and inferior mandibular nerve: ANTERIOR & MEDIAL, ANTERIOR, POSTERIOR & LATERAL,
POSTERIOR
234. Aciduric bacteria: LACTOBACILLUS
235. Streptococcus lacks: LIPOPOLYSACCHARIDE
236. Frequent virulence factor: CAPSULE
237. Gram negative bacteria have: LIPOPOLYSACCHARIDE
238. Glucagon phosphorylase: RATE-LIMITING ENZYME IN GLYCONEOGENESIS
239. Form collagen, elastin and reticular fibers: FIBROBLAST
240. Bone and cartilage share all of the following, except: HIGHLY VASCULARIZED
241. Primary teeth have: LIGHTER COLOR
242. Lingual HOC of MX canine: CERVICAL 1/3
243. Cervical lines: ADJACENT CERVICAL LINES ARE THE SAME
Cervical lines on adjacent proximal surfaces of adjacent teeth have approximately the same depth of curvature.
244. Contact area: STABILIZE DENTAL ARCH, FORM EMBREASURES, PREVENT FOOD IMPACTION
245. What tooth does MX lateral incisor contact in an edge to edge position: NO TOOTH
When protrusive movement first occurs, they contact MN lateral & canine.
246. Mesial contact point on MX canine: JUNCTION OF INCISAL & MIDDLE THIRD
247. Caries on MX lateral: LINGUAL PIT
248. Left MX 2nd premolar replaces which tooth: PRIMARY 2ND MOLAR
249. Cingulum of the MX central incisor offsets to: DISTAL
250. Occlusal view of MX 1st molar: M-D WIDTH IS WIDER ON LINGUAL THAN FACIAL
This is why the facial embrasure is larger than the lingual one, which is unique to the 1 st MX molars.
251. Tooth frequently found with 2 canals: MX 1st PM, MN LATERAL INCISOR (28%)
252. Root with 2 canals: MB OF MX 1ST MOLAR, M OF MN 1ST MOLAR, MN LATERAL INCISOR (28%)
253. MX 2nd molar: 3 ROOTS, 3 OR 4 CANALS; STENSON’S DUCT OPENS NEAR IT
254. MX 1st molar: 3 ROOTS, 3 OR 4 CANALS (2 MB, 1 P, 1 DB)
255. Straight mesial surface (looking from labial): MN CANINE
256. How many fossae does MX canine have: 2 LINGUAL FOSSAE
257. Which of the following is bordered by incisal edge and marginal ridges: OCCLUSAL TABLE
258. Which tooth exhibits most deformities: MX LATERAL INCISOR
259. Each of the following is a histologic feature of malignant growth, except: APLASIA & METAPLASIA
In light microscopy (LM): necrosis of alveolar walls - loss of nuclei, alveolar hemorrhage, +/- evidence of underlying cause.
Red infract: lung, brain, liver, intestine; white infract: kidney, retina, brain, heart, spleen
Centric relation: muscles, condyle in the back position. Central occlusion: teeth.
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266. Protrusion: BOTH LATERAL PTERYGOIDS
267. Stabilize the disc of TMJ: SUPERIOR HEAD OF LATERAL PTERYGOID
268. Left movement: RIGHT LATERAL PTERYGOID CONTRACTION
269. Translation: SUPERIOR COMPARTMENT
270. Articular surfaces of the condyle: SUPERIOR & ANTERIOR
271. Leukocytes leaves vessels at: POSTCAPILLARY VENULES
272. Secrete HCl: OXYNTIC / PARIETAL CELLS
273. Which of the following is incorrect: ALCOHOLISM CAUSES GUMMATOUS NECROSIS (it is rescricted to necrosis involving
spirochaetal infections that cause syphilis)
Apoptosis and necrosis: two types of cell death in alcoholic liver disease. Heavy alcohol consumption over long periods of time c an
result in severe liver damage, including death of liver cells (hepatocytes). Two mechanisms, apoptosis and necrosis, can contribute to
hepatocyte death.
Oral, weakened (OPV) SABIN Sabina gives blow-jobs (so you know the other one is intravenous, not oral)
Injection, inactivated (killed, IPV) SALK K → killed (so you know the other one is alive, not killed)
Morphologically, the synovial membrane consists of two layers: an inner cell layer (intima) and a support layer (vascular subintima),
which mixes with the fibrous capsule.
The intima consists of cells embedded in an amorphous, fiber-free matrix with an approximate thickness of one to four cells. It contains
macrophage-like type A cells with phagocytic ability, and fibroblast-like type B cells that synthesize proteins, glycoproteins, and
proteoglycans.
The subintima consists of loose CT with blood vessels, fibroblasts, macrophages, mastocytes, adipose cells, and some elastic fibers that
prevent membrane folding.
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287. Calcification begins at: INCISAL EDGE (if DEJ is not an option)
288. Inferior borders of TMJ are formed by: CONDYLES
289. Temporomandibular ligament attaches to: CONDYLE
290. Most anterior & superior position of TMJ: CR
291. Fractured neck of the condyle: MOUTH OPENING IS RESTRICTED, 30 mm (normal: 40-55 mm)
292. Deformed teeth: SYPHILLIS
Amelogenesis imperfecta is characterized by defective or missing tooth enamel. Secondary effects of this disorder may be early tooth
loss, heightened susceptibility to disease of the tissues surrounding the teeth (periodontal) such as gums, cement, ligaments, and the
bone in which the tooth root rests (alveolar).
Contents of PDL: fibroblasts (MC), cementoblasts, cementoclasts, osteoblasts, osteoclasts, macrophages, mast cells, eosinophils,
undifferentiated mesenchymal cells.
Ground substance: proteoglycans, GAGs, glycoproteins, water.
296. Pulp decreases in size due to: THERMAL SHOCK, NORMAL PHYSIOLOGIC & MASTICATORY FUNCTIONS, EXCESSIVE ATTRITION
& ABRASION, AGE, INJURY
297. Why MX molars have a bulbous shape? PRESENCE THE CUSP OF CARABELLI, CONSTRUCTION AT CERVICAL THIRD IN PRIMARY
TEETH, TO AID IN LATERAL MOVEMENT OF MN MOLARS
298. MX canine: DICTATES THE MORPHOLOGY OF THE BONE
Permanent maxillary canines have roots that, although under bone, dictate overlying cortical bone morphology.
The bulge created by the maxillary canine's roots is known as the canine eminence. This bulge is easily palpable.
Initiation of calcification: 4 – 5 Months
Completion of enamel: 6 – 7 Years
Eruption: 11 – 12 Years
Root completion: 13 – 15 Years
Crepitus (grinding sound) is usually an indication of advanced TMJ damage (degenerative changes). Crepitus is usually due to a tear in
the disc or the posterior attachment which produces bone to bone contact of the mandibular condyle with the joint socket in the base
of the skull (glenoid fossa).
300. Why capillaries have the slowest flow: GREATER CROSS SECTION AREA
The reason of the slower flow of the capillaries is that their united area is considerably greater than that of the arteries supplying them,
so that the same quantity of blood flowing through them in a given time has a wider channel to flow in and therefore moves mo re
slowly.
Substances pass through the capillary wall by diffusion, filtration, and osmosis. Oxygen and carbon dioxide move across the capillary
wall by diffusion. Fluid movement across a capillary wall is determined by a combination of hydrostatic and osmotic pressure. The net
result of the capillary microcirculation created by hydrostatic and osmotic pressure is that substances leave the blood at one end of the
capillary and return at the other end.
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301. Pitch of sound: FREQUENCY
302. What does not cause edema: SHOCK (this is not a correct answer)
303. NADPH is not necessary for: GLYCOLYSIS
304. After dental prophylaxis: BACTERIEMIA
305. Lateral bone of the face: ZYGOMATIC
306. Sensory to lower lip: MENTAL NERVE
307. Diuretic medication for hypertension: INHIBIT ADH
The jaw jerk reflex (masseter reflex) is a stretch reflex used to test the status of CN V and to help distinguish an upper cervical cord
compression from lesions that are above the foramen magnum.
The mandible is tapped at a downward angle just below the lips at the chin while the mouth is held slightly open. In response, the
masseter muscles will jerk the mandible upwards. Normally this reflex is absent or very slight. However, in individuals with UMN lesions
the jaw jerk reflex can be quite pronounced.
The jaw jerk reflex can be classified as a dynamic stretch reflex. The response to the stimulus is monosynaptic, with sensory neurons of
the trigeminal mesencephalic nucleus sending axons to the trigeminal motor nucleus, which in turn innervates the masseter. This reflex
is used to judge the integrity of the upper motor neurons projecting to the trigeminal motor nucleus. Both the sensory and mo tor
aspects of this reflex are through CN V.
Syncope is a temporary loss of consciousness usually related to insufficient blood flow to the brain. It’s also called fainting or "passing
out”. It most often occurs when blood pressure is too low (hypotension) and the heart doesn't pump enough oxygen to the brain. It can
be benign or a symptom of an underlying medical condition.
314. All of the following are a part of normal flora except: BORDETELLA PERTUSSIS
315. RBC in hypotonic solution, what happens: SWELL & BURST (HEMOLYSIS)
316. Replacement of dog aorta with rigid tube: SYSTOLIC PRESSURE, DIASTOLIC PRESSURE, WIDE PULSE PRESSURE,
CONTINUOUS FLOW IN THE CAPILLARIES WOULD CHANGE INTO PULSATILE FLOW
317. Atmospheric pressure is given, how much O2 tension should be: 20% OF GIVEN ATMOSPHERIC PRESSURE OF OXYGEN = PARTIAL
PRESSURE OF OXYGEN
318. Phenylketonuria, which enzyme is defected: PHENYLALANINE HYDROXYLASE
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329. Bacillary dysentery: SHIGELLA SPP.
330. Metastatic calcifications: HYPERPARATHYRODISM
Metastatic calcification is the deposition of calcium salts in otherwise normal tissue, because of serum levels of calcium, which can
occur because of deranged metabolism as well as increased absorption or decreased excretion of calcium and related minerals, as seen
in hyperparathyroidism. This occurs either from the parathyroid glands in appropriately making too much PTH (primary
hyperparathyroidism) or other events triggering increased production by the parathyroid glands (secondary hyperparathyroidism).
Most people with primary disease have no symptoms at the time of diagnosis. In those with symptoms the most common is kidney
stones with other potential symptoms including weakness, depression, bone pains, confusion, and increased urination. Both typ es
increase the risk of weak bones.
Primary hyperparathyroidism in 80% of cases is due to a single benign tumor known as a parathyroid adenoma with most of the rest
of the cases due to a multiple benign tumors. Rarely it may be due to parathyroid cancer. Secondary hyperparathyroidism typically
occurs due to vitamin D deficiency, chronic kidney disease, or other causes of low blood calcium. Diagnosis of primary disease is by
finding a high blood calcium and high PTH levels.
331. Which of the following scenarios would cause the greatest decrease in resistance in a single artery (2 mm long,
radius: 1,2 mm): INCREASING THE RADIUS OF THE ARTERY BY A FACTOR OF 2
332. Abnormal relation between the crown and the root: DILACERATION
333. Where can you find Raschkow plexus: ADJACENT TO THE CELL FREE ZONE
334. Organisms that cause athlete’s foot: TRICHOPHYTON
335. Disease caused by prions: TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHY (TSE): CREUTZFELD-JACOB DISEASE IN
HUMANS / MAD COW DISEASE IN COWS
Superior to inferior:
Right lung eparietal bronchus, pulmonary artery, hyparietal bronchus, vein
Left lung pulmonary artery, bronchus, vein
S cells: release secretin, found in the jejunum and duodenum. They are stimulated by a drop of the secretion of bicarbonate (HCO3−)
into the lumen, via the pancreas. This is primarily accomplished by an increase in cyclic AMP that activates CFTR to releas e chloride
anions into the lumen.
345. ADH & aldosterone: ADH WORKS ON THE COLLECTING DUCT, ALDOSTERONE ON THE DISTAL CONVOLUTED TUBULE &
COLLECTING DUCT
346. Aldosterone action: Na+ AND WATER ABSORPTION
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Aldosterone – primary effect is on the kidney tubules, where it stimulates Na+ retention and K+ excretion; collecting tubule: reabsorbs
water (controlled by ADH = vasopressin).
349. Structures in the sphenoid bone: SUPERIOR ORBITAL FISSURE & OPTIC CANAL
350. Structures passing by foramen rotundum: V2
351. Which muscle is not affected by a patient that had stroke on the motor lesion on the left side of below eye muscles: UPPER
THIRD MUSCLES OF FACIAL EXPRESSION & GENIOGLOSSUS
All cranial nerve motor nuclei have unilateral corticonuclear connections except:
1. CN VII: upper third mm. of facial expression have bilateral innervation
2. CN XII: genioglossus muscles have bilateral muscle innervaton.
353. Which branch of carotid artery is not in the carotid triangle: SUPERFICIAL TEMPORAL
354. MOA of rifampin: INHIBITS RNA SYNTHESIS (& PROTEIN SYNTHESIS) BY INHIBITING THE DNA-DEPENDENT RNA POLYMERASE
Rifampicin inhibits bacterial protein synthesis by inhibiting bacterial DNA-dependent RNA polymerase. It binds away from the active
site. The inhibitor prevents RNA synthesis by physically blocking elongation, and thus preventing synthesis of host bacterial proteins.
By this "steric-occlusion" mechanism, rifampicin blocks synthesis of the second or third phosphodiester bond between the nucleotides
in the RNA backbone, preventing elongation of the 5' end of the RNA transcript past more than 2 or 3 nucleotides.
Fluorouracil (Adrucil) is a medication used to treat cancer by injection into a vein it is used for colon cancer, esophageal cancer, stomach
cancer, pancreatic cancer, breast cancer, and cervical cancer. As a cream it is used for actinic keratosis and basal cell carcinoma.
Common side effects include inflammation of the mouth, loss of appetite, low blood cell counts, hair loss, and inflammation of the skin.
When used as a cream irritation at the site of application may occur. Use of either form in pregnancy may harm the baby. Fluorouracil
is in the antimetabolite and pyrimidine analog families of medications. How it works is not entirely clear but believed to involve blocking
the action of thymidylate synthase and thus stopping the production of DNA.
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356. MOA of sulfonamides: COMPETE WITH PABA TO INHIBIT FOLIC ACID SYNTHESIS
357. MOA of aminoglycosides: BIND TO 30S RIBOSOMAL SUBUNITS & INHIBIT TRANSLATION
358. MOA of digoxin: BLOCKS VOLTAGE GATED CHANNELS, CARDIAC GLYCOSIDE
Associate acidosis & hyperkalemia – when there is an excess of H+ in the blood, K+ leaves the cell in exchange for H+.
Kussmaul breathing is a deep and labored breathing pattern often associated with severe metabolic acidosis, particularly diabetic
ketoacidosis (DKA) but also kidney failure. It is a form of hyperventilation, which is any breathing pattern that reduces carbon dioxide
in the blood due to increased rate or depth of respiration.
Neisseria meningitidis, often referred to as meningococcus, is a Gram-negative bacterium that can cause meningitis.
Lipopolysaccharide is a component of the outer membrane of N. meningitidis. This acts as an endotoxin and is responsible for septic
shock and hemorrhage due to the destruction of red blood cells. Other virulence factors include a polysaccharide capsule which prevents
host phagocytosis and aids in evasion of the host immune response; fimbriae mediate attachment of the bacterium to the epithelial
cells of the nasopharynx.
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372. Kidney end of a proximal tubule osmotic pressure: ISOOSMOTIC PRESSURE
373. How does the osmotic pressure change in the distal part of the proximal convoluted tubule: NO CHANGE
374. Where can you find the highest osmolarity in the renal system: THE ASCENDING LOOP OF HENLE
375. Anterior cerebral artery supplies which lobes: FRONTAL AND PARIETAL
Histoplasmosis (“Cave disease”, "Darling's disease”, "Ohio valley disease”, "reticuloendotheliosis”) is a disease caused by the fungus
Histoplasma capsulatum. The disease affects primarily the lungs. Occasionally, other organs are affected; this is called disseminated
histoplasmosis, and it can be fatal if left untreated. Histoplasmosis is common among AIDS patients because of their suppressed
immunity. In immunocompetent individuals, past infection results in partial protection against ill effects if reinfected. Histoplasma
capsulatum is found in soil, often associated with decaying bat guano or bird droppings. Disruption of soil from excavation or
construction can release infectious elements that are inhaled and settle into the lung.
381. In the dental plaque (other than bacterial acidic enzyme): DEXTRAN
382. Major component of PDL: COLLAGEN
383. Where does Sharpey’s fiber insert: ACELLULAR EXTRINSIC FIBER CEMENTUM
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384. Alveolar crest: 1-2 mm BELOW CEJ
385. Location of CEJ: 1-2 mm OVER THE ALVEOLAR BONE
386. Patient with cirrhosis: MALLORY BODIES IN CYTOPLASM OF HEPATOCYTES
Mallory bodies are classically found in the livers of people suffering from alcoholic liver disease and were once thought to be specific
for that. They are MC in alcoholic hepatitis (65%) and alcoholic cirrhosis (51%). They are a recognized feature of Wilson's disease (25%),
primary biliary cirrhosis (24%), non- alcoholic cirrhosis (24%), hepatocellular carcinoma (23%) and morbid obesity (8%), among other
conditions.
Meningitis
1. Neonates E. coli
2. Infants and children H. influenzae
3. Young adults N. meningitis
4. Older adults S. pneumoniae
392. Which factor plays an important role in detecting the initiation factor for RNA transcription? SIGMA
393. Gas gangrene has what kind of enzymatic activity: GANGRENOUS NECROSIS
394. MOA of tetanus toxin: INHIBITION OF NT RELEASE
395. What protozoa are spread in cat feces: TOXOPLASMOSA GONDII
396. Which of the following is carried by a vector: RICKETSSIA
Rickettsia is a nonmotile, gram-negative, nonspore-forming, highly pleomorphic bacteria that can be present as cocci, rods, or
thread-like. Being obligate intracellular parasites, the Rickettsia survival depends on entry, growth, and replication within the
cytoplasm of eukaryotic host cells (typically endothelial cells). Rickettsia cannot live in artificial nutrient environments and is grown
either in tissue or embryo cultures; typically, chicken embryos are used.
397. Antigenicity that changes from season to season: ANTIGENIC CAPSULE SPIKES CONTAINING NURAMINIDASE AND
HEMAGGLUTININ (H. influenzae)
398. Influenza antigenicity due to: GLYCOPROTEINS / ANTIGENIC DRIFT
399. Iron in serum plasma is carried by: TRANSFERRIN
400. All are organelles except: FAT DROPLETS
401. What is the final electron receptor in ETC: OXYGEN
402. What measures partial pressure of oxygen: CAROTID BODY
The carotid body is a small cluster of chemoreceptors and supporting cells located near the bifurcation of the carotid artery. It detects
changes in the composition of arterial blood flowing through it, mainly the partial pressure of oxygen, but also of carbon dioxide.
Furthermore, it is also sensitive to changes in pH and temperature.
403. Hyperventillation alters the acid balance of arteries by: CO2 & pH
404. Which layer of epidermis does not have tonofilaments: BASALE
1. Stratum Basale: the deepest layer, has keratinocytes, the keratinocytes are attached to the basement membrane by
hemidemosomes.
2. Stratum Spinosum: high molecular weight keratin with a lot of tonofilaments
3. Stratum Granulosum: disulfide bonds begin to cross-link with tonofilaments.
4. Stratum Lucidum: the cytoplasm consists almost entirely of tonofilaments.
5. Stratum Corneum: the most superficial layer, the cells are called squames, filled with cross linked of tonofilaments.
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405. What will you find in stratum granulosum: KERATOHYALIN GRANULES
406. Which organ has activated PCK: BRAIN
Phosphoenolpyruvate carboxykinase
While PCK1 is mainly expressed in the liver and kidney, PCK2 is ubiquitously expressed in various cell types,
including leukocytes and neurons, as well as in non-gluconeogenic tissues like pancreas, brain, heart. Moreover, while PCK1 expression
is regulated by hormones or nutrients involved in gluconeogenesis, PCK2 is constitutively expressed. These differences indicate that
PCK2 may also perform non-gluconeogenic functions.
407. What are the steps of DNA amplification: DENATURATION, ANNEALING, ELONGATION
All the PCR components are mixed together and are taken through series of 3 major cyclic reactions conducted in an automated, self-
contained thermocycler machine.
1. Denaturation:
Heating the reaction mixture to 94°C for 15-30 seconds → DNA is denatured to single strands due to breakage in weak hydrogen bonds.
2. Annealing:
Temperature is rapidly lowered to 54-60°C for 20-40 seconds → the primers bind (anneal) to their complementary sequence in the
template DNA.
3. Elongation (extension):
Occurs at 72-80°C (most commonly 72°C) → the polymerase adds bases to the 3′ each primer, extending the DNA sequence in the 5′ to
3′ direction. Under optimal conditions, DNA polymerase will add about 1,000 bp/minute.
With one cycle, a single segment of double-stranded DNA template is amplified into two separate pieces of double-stranded DNA.
These two pieces are then available for amplification in the next cycle. As the cycles are repeated, more and more copies are generated
and the number of copies of the template is increased exponentially.
Condyles of the mandible grow by endochondral ossification, whereas the rest of the mandible grow by intramembranous ossification.
413. Patient with DM type 1 (insulin: 2 x a day), hypertensive, but taking medication for it, during dental visit he passes out & is pale.
What is not the reason: HYPERGLYCEMIA
414. What is needed for coagulation: Ca2+
415. Where does N-glycosylation occur: RER; BETWEEN SUGARS & AA
416. Hormone dependent physiologic/pathologic involution: APOPTOSIS
417. Predominant cell in an acute inflammation: NEUTROPHIL
418. 1st cells to appear in an acute inflammation: NEUTROPHILS
419. While draining an abscess from a lower molar, what kind of cell will predominate: NEUTROPHIL
420. Bacteria most likely to be found in a foul-smell, purulent abscess (abscess on the lower mandible): ACTINOMYCES
421. Circumduction of the arm: DELTOID MUSCLE (axillary nerve)
422. Which one does not contribute to the posterior wall of axilla: SERRATUS ANTERIOR
423. Where does the esophagus begin: LOWER BORDER OF CIRCOID CARTILAGE (C6-T10)
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424. What surrounds a myelin sheath: ENDONEURIUM
425. What vitamin is needed for the hydroxylation of proline: VITAMIN C
426. What is not in periosteum: OSTEOCYTES
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Retinopathy is any damage to the retina of the eyes, which may cause vision impairment. Retinopathy often refers to retinal vascular
disease, or damage to the retina caused by abnormal blood flow. Age-related macular degeneration is technically included under the
umbrella term retinopathy but is often discussed as a separate entity. Retinopathy, or retinal vascular disease, can be broadly
categorized into proliferative and non- proliferative types. Frequently, retinopathy is an ocular manifestation of systemic disease as
seen in diabetes or hypertension. Diabetes is the most common cause of retinopathy in the USA. Diabetic retinopathy is the leading
cause of blindness in working-aged people. It accounts for about 5% of blindness worldwide and is designated a priority eye disease by
the WHO.
Burkitt’s lymphoma is a cancer of the lymphatic system, particularly B lymphocytes (B cells cause bone marrow replacement), found in
the germinal center. The endemic African variant MC occurs in children living in malaria endemic regions of the world, it involves jaw
and facial bones. In America, the abdomen is MC affected.
438. Diabetic patient, using insulin. What cells are destroyed: BETA CELLS
439. Patient with Grave’s disease, in lab findings you will see: TSH & T3, T4
Graves’ disease is an autoimmune disease that leads to a generalized over activity of the entire thyroid gland (hyperthyroidism,
thyrotoxicosis, diffuse toxic goiter). It is the MC cause of hyperthyroidism in the USA. It is 7-8 x MC in women than men (20-40 years
old). TSH is produced when the hypothalamus releases a substance called thyrotropin-releasing hormone (TRH). TRH then triggers the
pituitary gland to release TSH. TSH causes the thyroid gland to make two hormones: triiodothyronine (T3) and thyroxine (T4). T3 and
T4 help control your body's metabolism. Characterized by exophthalmos, tachycardia, heat intolerance, and fine tremor, warm, moist
skin, and fine hair. Range from anxiety & restlessness to insomnia & weight loss, eyeballs may begin to protrude (exophthalmos) causing
irritation & tearing.
TSH receptor: upon binding circulating thyrotropin, a G-protein signal cascade activates adenylyl cyclase and intracellular levels of
cAMP rise. cAMP activates all functional aspects of the thyroid cell, including iodine pumping; thyroglobulin synthesis, iodination,
endocytosis and proteolysis; thyroid peroxidase activity; and hormone release.
“The TSH receptor binding and thyroid stimulating properties of (Fab)2 and Fab fragments of Graves' IgG have been investigated.
(Fab)2 fragments were prepared by pepsin digestion of IgG and Fab fragments by reduction of (Fab)2 or papain digestion of IgG. (Fab)2
and Fab were effective in inhibiting TSH binding to its receptor with all five patients' sera studied and both preparations stimulated
cyclic AMP release from isolated thyroid cells. However Fab fragments were less active thyroid stimulators than their parent (Fab)2 in
all five cases. These studies indicate that antibody divalency is not essential for thyroid stimulation by TSH receptor antibodies.” – I
checked multiple articles and they were mentioning only FAB as a binding site.
2. Prolactin Inhibiting Factor (dopamine) is released from hypothalamus to act on anterior pituitary. When hypophyseal portal
system is cut, this inhibitory signal is banned → prolactin release will increase. By dissecting the infundibulum, the portal
system is going to remain intact, so there will be no effect in anterior pituitary hormones action.
Wikipedia: damage to the pituitary stalk blocks the release of antidiuretic hormone, resulting in polydypsia (abusive water intake) and
polyuria (excessive urination).
Unlike peristalsis, which predominates in the esophagus, segmentation contractions occur in the large intestine and small intestine,
while predominating in the latter. While peristalsis involves one-way motion in the caudal direction, segmentation contractions move
chyme in both directions, which allows greater mixing with the secretions of the intestines. Segmentation involves contractions of the
circular muscles in the digestive tract, while peristalsis involves rhythmic contractions of the longitudinal muscles in the gastrointestinal
tract. Unlike peristalsis, segmentation actually can slow progression of chyme through the system.
Thromboplastin (TPL) is a plasma protein aiding blood coagulation through catalyzing the conversion of prothrombin to thrombin. It is
a complex enzyme that is found in brain, lung, and other tissues and especially in blood platelets and that functions in the conversion
of prothrombin to thrombin in the clotting of blood—called also thrombokinase.
465. What cells are involved with type IV hypersensitivity: T CELLS & MACROPHAGES
466. Measles and rubeola, what virus: PARAMYXOVIRUS
467. Varicella and chickenpox, what virus: VARICELLA-ZOSTER VIRUS
468. Articular disc is made out of: FIBROCARTILAGE
469. Articular surfaces of a baby are made out of: HYALINE CARTILAGE
470. Tissue covering articular surfaces of TMJ: FIBROCARTILAGE
471. HOC on mesial of MAX canine: CERVICAL 1/3
472. Number of pulp horns in a newly erupted MN molar: 5
473. How many canals in MX 1st molar: 2MB, 1P, 1DB
474. Where is the accessory canal in MX 1st molar: MB ROOT
475. Mesial is straight in: MANDIBULAR CANINE
476. Broken cusp, what kind of movement: MEDIOTRUSIVE, NON-WORKING
477. Largest sinus infection (largest paranasal sinus) in the skull: MAXILLARY
478. Preganglionic nerve for otic ganglion: LESSER PETROSAL NERVE
479. What substance is used to measure GFR: INULIN
Inulin and it’s analog sinistrin are used to help measure kidney function by determining the glomerular filtration rate (GFR), which is
the volume of fluid filtered from the renal glomerular capillaries into the Bowman's capsule per unit time. Inulin is of particular use as
it is not secreted or reabsorbed in any appreciable amount at the nephron, allowing GFR to be calculated. However, due to clinical
limitations, inulin and sinistrin, although characterized by better handling features, are rarely used for this purpose and creatinine
values are the standard for determining an approximate GFR.
Hemolytic disease of the newborn (hemolytic disease of the fetus and newborn, HDN, HDFN, or erythroblastosis fetalis) is an
alloimmune condition that develops in a fetus, when the IgG molecules (one of the five main types of antibodies) produced by the
mother pass through the placenta. Among these antibodies are some which attack antigens on the RBC in the fetal circulation, breaking
down and destroying the cells (hemolysis). Alloimmunity (sometimes called isoimmunity) is an immune response to nonself antigens
from members of the same species, which are called alloantigens or isoantigens. Two major types of alloantigens are blood gro up
antigens and histocompatibility antigens. In alloimmunity, the body creates antibodies against the alloantigens, attacking transfused
blood, allotransplanted tissue, and even the fetus in some cases. Alloimmune (isoimmune) response results in graft rejection, which is
manifested as deterioration or complete loss of graft function.
482. Patient with lower denture complaining of burning sensation of buccal gingiva & side of lower lip, which nerve: MENTAL NERVE
483. What protrudes the hyoid bone: GENIOHYOID
484. Most abundant papillae: FILIFORM
485. Mandibular sling muscles: MEDIAL PTERYGOID & MASSETER
486. Which muscle retrudes the mandible: POSTERIOR FIBERS OF TEMPORALIS
487. What is the template & product of reverse transcriptase: TEMPLATE → RNA, PRODUCT → DNA
488. Increased condylar guidance: TALLER POSTERIOR CUSPS
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489. Where are found crypts of Lieberkühn: LAMINA PROPRIA OF THE SMALL INTESTINE
In histology, an intestinal gland (also crypt of Lieberkühn and intestinal crypt) is a gland found in the intestinal epithelium lining of the
small intestine and large intestine (colon). The glands and intestinal villi are covered by epithelium, which contains multiple types of
cells: enterocytes (absorbing water and electrolytes), goblet cells (secreting mucus), enteroendocrine cells (secreting hormones), cup
cells, tuft cells and, at the base of the gland, Paneth cells (secreting anti-microbial peptides) and stem cells. These cells are not all
present in the colon.
491. What is the least likely to be reproducible on semi-adjustable articulator: LATEROTRUSIVE MOVEMENT
492. Parasympathetic stimulation to salivary glands will cause: THIN SALIVA
Emphysema damages the inner walls of the lungs' air sacs (alveoli), causing them to eventually rupture. This creates one larger air
space instead of many small ones and reduces the surface area available for gas exchange.
494. Taller posterior cusps: INCREASED OVERBITE & STEEPER CONDYLAR GUIDANCE
495. TMJ disc is made from which embryonic cartilage: MECKEL’S CARTILAGE
496. Pregnant woman (6th week), what is present in the fetus that the mother doesn’t have: DUCTUS ARTERIOSUS
In the developing fetus, the ductus arteriosus (ductus Botalli) is a blood vessel connecting the pulmonary artery to the proximal
descending aorta. It allows most of the blood from the right ventricle to bypass the fetus's fluid-filled non-functioning lungs. Upon
closure at birth, it becomes the ligamentum arteriosum. There are two other fetal shunts, the ductus venosus and the foramen ovale.
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500. Root frequently found with two canals: MN 1st MOLAR (MESIAL ROOT)
501. Distal concavity: ON MX CANINE & MX 1st MOLAR (more pronounced)
502. Dead, old lady with signs of liver cirrhosis and change on the epithelium of the uterus: LEIOMYOMAS (FIBROIDS)
503. Crescent shaped central developmental groove: 2nd MN PREMOLAR (“U” shaped)
504. Very prominent triangular ridge: MN 1st PREMOLAR
505. Largest crown compared to MX central: MN CANINE
506. Where is crista terminalis: RIGHT ATRIUM
Gardner syndrome, a variant of familial adenomatous polyposis (FAP), is an autosomal dominant disease characterized by GI polyps,
multiple osteomas, and skin and soft tissue tumors. Cutaneous findings of Gardner syndrome include epidermoid cysts, desmoid tumors,
and other benign tumors. Polyps have a 100% risk of undergoing malignant transformation; consequently, early identification of
Gardner syndrome is critical.
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526. Where can we perform spinal tap (lumbar puncture): L3-L4
528. Patient with myasthenia gravis is most likely to have what kind of neoplasia: THYMOMA
A thymoma is a tumor originating from the epithelial cells of the thymus that may be benign or malignant. Thymomas are frequently
associated with the neuromuscular disorder myasthenia gravis; thymoma is found in 20% of patients with myasthenia gravis. Onc e
diagnosed, thymomas may be removed surgically. In the rare case of a malignant tumor, chemotherapy may be used. A third of all
people with a thymoma have symptoms caused by compression of the surrounding organs by an expansive mass. These problems may
take the form of superior vena cava syndrome, dysphagia (difficulty swallowing), cough, or chest pain. One-third to one-half of all
persons with thymoma have no symptoms at all, and the mass is identified on a chest X-ray or CT/CAT scan performed for an unrelated
problem.
Rhombencephalon:
- myelencephalon: medulla oblongata
- metencephalon: pons + cerebellum
Basal metabolic rate is a direct measure of temperature and indirectly by oxygen consumption. The most appropriate answer is the
amount of energy used.
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538. All muscles elevate larynx except: INFRAHYOID MUSCLES
544. Why do you need to tell her to take an extra care of her oral health: PREGNANCY-RELATED GINGIVITIS
545. Women secrete endometrium in which phase: LUTEAL PHASE
546. Rattle snake bite on a baby’s lateral forearm, what nerve injured: RADIAL NERVE
547. Proto/oncogene (?): CHROMOSOME 9 (c_abl)
Adenosine deaminase (ADA) deficiency is an inherited disorder that damages the immune system and causes severe combined
immunodeficiency (SCID). People with SCID lack virtually all immune protection from bacteria, viruses, and fungi. They are prone to
repeated and persistent infections that can be very serious or life-threatening. These infections are often caused by "opportunistic"
organisms that ordinarily do not cause illness in people with a normal immune system.
36
549. An 8-month-old male infant is admitted to the hospital because of a bacterial respiratory infection. The infant responds to
appropriate antibiotic therapy, but is readmitted several weeks later because of severe otitis media. Over the next several
months, the infant is admitted to the hospital multiple times for recurrent bacterial infections. Blood work reveals extremely
low serum antibody levels. The infant has no previous history of viral or fungal infection. The most likely diagnosis is: X-linked
agammaglobulinemia of Bruton
X-linked agammaglobulinemia (XLA) is a condition that affects the immune system and occurs almost exclusively in males. People with
XLA have very few B cells, which are specialized white blood cells that produce antibodies (immunoglobulins). Individuals with XLA are
more susceptible to infections because their body makes very few antibodies. Children with XLA are usually healthy for the first 1 or 2
months of life because they are protected by antibodies acquired before birth from their mother. After this time, the maternal
antibodies are cleared from the body, and the affected child begins to develop recurrent infections. In children with XLA, in fections
generally take longer and then they come back again. The most common bacterial infections that occur in people with XLA are lung
infections (pneumonia and bronchitis), ear infections (otitis), pink eye (conjunctivitis), and sinus infections (sinusitis). Infections that
cause chronic diarrhea are also common. Recurrent infections can lead to organ damage. People with XLA can develop severe, life-
threatening bacterial infections; however, affected individuals are not particularly vulnerable to infections caused by viruses. With
treatment to replace antibodies, infections can usually be prevented, improving the quality of life for people with XLA.
550. A woman is suffering from ulcerative gingivitis, labs show: 1200 ct of leukocytes, 98% of which are lymphocytes. Red blood cells
& thrombocytes counts are normal. What can be the diagnosis: AGRALUNOLYTOSIS, MULTIPLE MYELOMA, ACUTE
MYELOGENOUS LEUKEMIA, CHRONIC LYPHOBLASTIC LEUKEMIA.
Agranulocytosis (agranulosis / granulopenia) is an acute condition involving a severe and dangerous leukopenia (lowered white blood
cell count), MC of neutrophils causing a neutropenia in the circulating blood. It is a severe lack of one major class of infection-fighting
white blood cells. People with this condition are at very high risk of serious infections due to their suppressed immune system. In
agranulocytosis, the concentration of granulocytes (a major class of white blood cells that includes neutrophils, basophils, and
eosinophils) drops below 500 cells/mm³ of blood.
ADP/ATP translocases, also known as adenine nucleotide translocases (ANT) and ADP/ATP carrier proteins (AAC), are transporter
proteins that enable the exchange of cytosolic adenosine diphosphate (ADP) and mitochondrial adenosine triphosphate (ATP) across
the inner mitochondrial membrane.
Free ADP is transported from the cytoplasm to the mitochondrial matrix, while ATP produced from oxidative phosphorylation is
transported from the mitochondrial matrix to the cytoplasm, thus providing the cells with its main energy currency. Under normal
conditions, ATP and ADP cannot cross the inner mitochondrial membrane due to their high negative charges, but ADP/ATP translocase,
an antiporter, couples the transport of the two molecules. The depression in ADP/ATP translocase alternatively faces the matrix and
the cytoplasmic sides of the membrane. ADP in the intermembrane space, coming from the cytoplasm, binds the translocase and
induces its eversion, resulting in the release of ADP into the matrix. Binding of ATP from the matrix induces eversion and results in the
release of ATP into the intermembrane space, subsequently diffusing to the cytoplasm, and concomitantly brings the translocase back
to its original conformation. ATP and ADP are the only natural nucleotides recognized by the translocase.
552. Disease of destruction of bronchi and bronchiole with mucus: ASTHMA, BRONCHOPNEUMONIA, EMPHYSEMA
Asthma is the result of chronic inflammation of the conducting zone of the airways (most especially the bronchi and bronchioles), which
subsequently results in increased contractability of the surrounding smooth muscles and mucous production.
Pneumonia is a category of lung infections. It occurs when viruses, bacteria, or fungi cause inflammation and infection in the alveoli
(tiny air sacs) in the lung. Bronchopneumonia, or lobular pneumonia, is a type of pneumonia that also causes inflammation in the
bronchi. These are the air passages that feed air into the lungs. Also excessive mucous production occurs.
If there will be no hints about asthma (shortness of breath, wheezing, genetic & enviromental factors, drugs taken) we should go with
bronchopneumonia.
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553. Muscles of the sound: LATERAL AND TRANSVERSE CRICOARTYNOIDS
554. Centroacinar cells: PANCREAS
556. Anterior cerebral artery supply: MEDIAL SURFACE OF FRONTAL & PARIETAL LOBES
557. Middle cerebral artery supplies: PORTION OF THE FRONTAL LOBE, LATERAL SURFACE OF THE TEMPORAL & PARIETAL LOBES
(including the primary motor & sensory areas of the face, throat, hand and arm and, in the dominant hemisphere, the areas of
speech)
558. Covers articular surfaces: FIBROCARTILAGE (disc is made out of dense fibrous CT and on the outside there is fibrocartilage)
559. Meckel’s cartilage: FORMS AT 4th WEEK IN UTERO
560. Cystic fibrosis is diagnosed by: SWEAT TEST → Cl- + Na+
561. Patient has dysphonia, dysphagia, weight loss. He is a long-time heavy smoker: CARCINOMA OF THE LARYNX
562. Synthesis of histones for DNA, which phase: THE BEGINNING OF THE S PHASE
563. Found on mutation and cause improper metabolism: ONCOGENE
Oncogenes are key drivers of tumor growth. Although several cancer-driving mechanisms have been identified, the role of oncogenes
in shaping metabolic patterns in cancer cells is only beginning to be appreciated. Recent studies show that oncogenes directly regulate
critical metabolic enzymes and metabolic signaling pathways.
564. Diagnostic features of a breast cancer: PEAU DE ORANGE, FIXITY TO UNDERLYING TISSUES, BRCA1 & BRCA2
565. Thoracic duct position: POSTERIOR TO ESOPHAGUS
566. When you make a cut at recess of larynx, which nerve is least affected: RECURRENT LARYNGEAL
38
567. Intracellular fungus: HISTOPLASMA CAPSULATUM
568. On your articulator, altering horizontal condylar guidance will affect all of the following except: LATEROTRUSIVE MOVEMENT
If you take a look at the picture above you will find, that condylar path is making an angle with the horizontal plane and that angle is
called 'horizontal condylar path angle', which determines the steepness of the articular eminence, which will affect the anterior
guidance and cusp heights as well.
To my knowledge the horizontal condylar guidance is related to an anteroposterior plane. Its alteration does not affect laterotrusive
or mediotrusive movements.
569. Blood flow relation in arteries and veins: BLOOD FLOW IS THE SAME AS IN ARTERIES (the amount of blood, not velocity)
570. Blood flow in capillaries: THE SAME AS IN ARTERIES (read: the same amount of blood goes through the capillaries and arteries
in a unit of time; the velocity is slower, but the amount of blood transported is the same).
571. Heart congestion leads to: PULMONARY EDEMA
Pulmonary edema is an acute left ventricle failure when the left ventricle can’t push the blood to the aorta, so the blood remains in the
lungs and cause pulmonary hypertension.
Cor pulmonale: due to failure in right ventricle, which is due to pulmonary hypertension.
572. What does skeletal muscle, smooth muscle, cardiac muscle all have in common: TROPOMYOSIN, LITTLE REGENERATIVE
CAPACITY, SARCOPLASMIC RETICULUM, NUCLEUS
573. Inferior thyroid develops from: 3rd ARCH
574. Hyoid bone develops mainly from: 2nd & 3rd ARCH
39
575. Regeneration of pyruvate by: LACTATE DEHYDROGENASE
In the second half of Cori Cycle, lactate is converted to pyruvate by LDH in the liver.
576. Obstruction of ext. auditory meatus due to defect in: 1st PHARYNGEAL CLEFT
A pharyngeal groove (branchial groove or pharyngeal cleft) is made up of ectoderm unlike its counterpart the pharyngeal pouch on the
endodermal side. The 1st pharyngeal groove produces the external auditory meatus (ear canal). The rest (2 nd, 3rd and 4th) are overlapped
by the growing 2nd pharyngeal arch and form the floor of the depression termed the cervical sinus, which opens ventrally, and is finally
obliterated.
577. Cranial base of a newborn is made of: HYALINE CARTILAGE BY ENDOCHONDRAL OSSIFICATION
578. Epithelial lining from ventral to dorsal surface: SURGERY
579. How to measure nitrous oxide inhalation: RESPIRATORY MINUTE VOLUME (RMV)
580. Metabolic acidosis is associated with: HYPERKALEMIA
Isoelectric point is the pH at which the substance has no charge, so the question & answer make sense and are correct.
585. Brain abscess: LIQUEFACTIVE NECROSIS (enzymatic digestion, suppuration, loss of tissue attachment)
586. All cause brain abscess except: TINEA PEDIS
Tinea pedis (fungi) is thought to be the world's MC dermatophytosis. Reportedly, 70% of the population will be infected with tinea pedis
at some time. Tinea pedis is the term used for a dermatophyte infection of the soles of the feet and the interdigital spaces. Tinea pedis
is MC caused by Trichophyton rubrum, a dermatophyte initially endemic only to a small region of Southeast Asia and in parts of Africa
and Australia. Using enzymes called keratinases, dermatophyte fungi invade the superficial keratin of the skin, and the infection
remains limited to this layer. Dermatophyte cell walls also contain mannans, which can inhibit the body's immune response.
40
587. Ligament active during yawning: OBLIQUE FIBERS OF THE TMJ LIGAMENT (if not an option pick spheno/stylomandibular)
588. All can cause painless hematuria except: NEPHROLITHIASIS
Painless hematuria as a common early clinical sign in acute diffuse glomerulonephritis, carcinoma of the bladder, focal
glomerulonephritis, and renal cell carcinoma.
Pertussis (whooping cough, a 100-day cough) is a highly contagious bacterial disease. Initially, symptoms are usually similar to those
of the common cold with a runny nose, fever, and mild cough. This is then followed by weeks of severe coughing fits. Following a fit of
coughing, a high-pitched whoop sound or gasp may occur as the person breathes in. The coughing may last for 10 or more weeks,
hence the phrase "100-day cough". A person may cough so hard that they vomit, break ribs, or become very tired from the effort.
Children less than one year old may have little or no cough and instead have periods where they do not breathe.
Proline-rich proteins are major components of parotid and submandibular saliva. They can be divided into acidic, basic and glycosylated
proteins. The primary structure of the acidic proline-rich proteins is unique and shows that the proteins do not belong to any known
family of proteins. The proline-rich proteins are apparently synthesized the acinar cells of the salivary glands and their phenotypic
expression is under complex genetic control. The acidic proline-rich proteins will bind calcium with a strength which indicates that they
may be important in maintaining the concentration of ionic calcium in saliva.
593. Ksp solubility constant of ions (they were asking how do ions precipitate): PRODUCT CONCENTRATION OF IONS
595. Submandibular gland: SECRETES MORE VOLUME OF SALIVA (the next is parotid)
596. More saliva is secreted: BETWEEN MEALS
597. Cause of a massive hematemesis in alcoholics: ESOPHAGEAL VARICES
I was taught at school that sublingual is a mixed gland, just like submandibular. Sublingual was mostly mucous and submandibular
mostly serous.
600. Changes in aorta with age: BECOMES STIFF, LESS ELASTIC; SYSTOLE + NO CHANGE/ DIASTOLE → WIDE PULSE PRESSURE
601. Dissection after emerge from stylomastoid foramen, what happens: IPSILATERAL PARALYSIS OF MM. OF FACIAL EXPRESSION
= LOWER MOTOR NEURON OF VII
The Edinger–Westphal nucleus (accessory oculomotor nucleus) is the parasympathetic, pre-ganglionic nucleus that innervates the iris
sphincter muscle and the ciliary muscle.
42
606. Virus attached to MHC I responds to: VIRAL PEPTIDE
As viruses induce cellular expression of viral proteins, some of these products are tagged for degradation, with the resulting peptide
fragments binding to MHC I molecules. It is in this way, the MCH I dependent pathway of antigen presentation, that the virus infected
cells signal T cells that abnormal proteins.
607. How does the space between teeth change with age: IT GETS LARGER
608. Allosteric activator: AMP, Pi, FRUCTOSE-2,6-BISPHOSPHATE
609. In allergy, IgE binds to: MAST CELLS
610. Soft tissue and bone in a fracture: METAPLASIA
611. Pterygomandibular raphe, origin & insertion: SUPERIORLY TO THE HAMULUS OF MEDIAL PTERYGOID PLATE (SPHENOID
BONE) & INFERIORLY TO THE POSTERIOR END OF THE MYLOHYOID LINE OF THE MANDIBLE
Disorders of this protein include alpha-1 antitrypsin deficiency, an autosomal codominant hereditary disorder in which a deficiency of
alpha-1 antitrypsin leads to a chronic uninhibited tissue breakdown. This causes the degradation especially of lung tissue and eventually
leads to characteristic manifestations of pulmonary emphysema. Evidence has shown that cigarette smoke can result in oxidation
of methionine of α1-antitrypsin, a residue essential for binding elastase; this is thought to be one of the primary mechanisms by which
cigarette smoking (or second-hand smoke) can lead to emphysema. Because A1AT is expressed in the liver, certain mutations in
the gene encoding the protein can cause misfolding and impaired secretion, which can lead to liver cirrhosis.
614. White rami: CENTRAL IN THE BRAIN, PERIPHERAL IN THE SPINAL CORD; MYELINATED AXONS
615. Myocardial infraction after 24h: COAGULATIVE NECROSIS
616. Infract healing: BY ORGANIZATION
• 0-24 hours - early coagulative necrosis, edema, hemorrhage, neutrophils appear, hyper contraction of myofibrils
• 1-3 days - extensive coagulative necrosis
• 3-14 days - macrophages, then granulation tissue at margins
• 2 weeks-several months - contracted scar complete
617. All in the sphenoid bone except: CAROTID CANAL (temporal bone)
618. Smallest cusp in MN 1st molar: DISTAL
619. Vesicles on the skin at nerve distribution, either small, recurrent chicken pox: HERPES ZOSTER
620. Ergosterol synthesis is blocked by: NYSTATIN
621. Nystatin: MOST COMMON ANTIFUNGAL
622. Cirrhosis commonly is caused by: ALCOHOLISM
623. Which enzyme is associated with phosphorylation of ADP at a substrate level: PYRUVATE KINASE
624. Toxoid vaccine, inactivated: EXOTOXIN
625. Small cell carcinoma: BRONCHIAR
626. HPV infection, not prevented by a vaccine: CONDYLOMATA ACUMINATUM (GENITAL WART)
43
627. Myasthenia gravis: ACH
628. The effect of Ach on neuromuscular junction, it opens what: VOLTAGE GATED ION CHANNELS, CHEMICAL GATED CATION
CHANNELS
629. ACE inhibitors cause: XEROSTOMIA
630. What dilates pupils: EPINEPHRINE
631. Ganglion with nerves that dilate the pupil: SUPERIOR CERVICAL GANGLION (picture on page 41)
632. Mucormycosis infects: BLOOD VESSELS
Mucormycosis is any fungal infection caused by fungi in the order Mucorales (species: Mucor, Rhizopus). The disease is often
characterized by hyphae growing in and around blood vessels and can be potentially life-threatening in diabetic or severely
immunocompromised individuals.
Histoplasmosis is thermally dimorphic. The mold form produces tuberculate chlamydospores (asexual spores, like arthrospores).
635. Not in a cell membrane: TRIGLYCERIDES (cholesterol & phospholipids are present)
636. If the anticodon on tRNA is 5’ ACG 3’, then which of the following is it’s corresponding codon on mRNA: 5’ CGU 3’
637. mRNA by which blot: NORTH
44
640. Tyrosine kinase, receptor: INSULIN RECEPTOR
The insulin receptor is a transmembrane receptor that is activated by insulin, IGF-I, IGF-II and belongs to the large class of tyrosine
kinase receptors. Metabolically, the insulin receptor plays a key role in the regulation of glucose homeostasis, a functional process that
under degenerate conditions may result in a range of clinical manifestations including diabetes and cancer.
642. Problem in root planning common with all posterior teeth: FACIAL CERVICAL BULGE
643. Rickettssia infection not transmitted by ticks: Q FEVER
Q fever is a disease caused by infection with a bacterium Coxiella burnetti. This organism is uncommon, but may be found in cattle,
sheep, goats, and other domestic mammals, including cats and dogs. The infection results from inhalation of a spore-like small-cell
variant, and from contact with the milk, urine, feces, vaginal mucus, or semen of infected animals. Rarely, the disease is tick-borne.
The diaphragm is primarily innervated by the phrenic nerve (C3, C4, C5). While the central portion of the diaphragm sends sensory
afferents via the phrenic nerve, the peripheral portions of the diaphragm send sensory afferents via the intercostal (T5–T11) and
subcostal nerves (T12).
650. Deep lingual artery ends on: THE TIP OF THE TONGUE
45
655. 3rd order pain neurons in: THALAMUS
The substantia nigra is a basal ganglia structure located in the midbrain that plays an important role in reward and movement.
Thymine dimer is an example of frameshift mutation. It can be corrected by photoreactivation. 2nd step is nucleotide excision.
Valine and leucine can be found in globular proteins. Generally speaking, interior AA are hydrophobic.
Hydrophobic AA: phenylalanine, proline, tryptophan, tyrosine, valine, leucine, isoleucine
Hydrophilic AA:
- positive: arginine, histidine, lysine
- negative: aspartate, glutamate
- neutral: serine, threonine, cysteine, methionine, asparagine, glutamine
666. Decrease in plasma osmotic pressure will cause diluted urine: FALSE
Edema:
1. in hydrostatic pressure
2. in colloid osmotic pressure (oncotic pressure)
Decrease in colloid osmotic pressure leads to increase in edema, which leads to decrease in urine output, so the urine will b e more
concentrated.
46
667. Asthma: TYPE 1 HYPERSENSITIVITY
668. Liver’s function, all except: PRODUCTION/STORAGE/SECRETING OF DIGESTIVE ENZYMES (different questions with different
answer choices, I combined all three here)
669. Normal flora of nasopharynx: S. EPIDERMIS
670. Right lateral excrusion, mesiofacial cusp of the MX R 1 st molar passes through which of the following grooves of MN R 1st molar:
DISTO BUCCAL GROOVE
671. RSV infection can be prevented by vaccination: FALSE
672. Penicillin hypersensitivity: TYPE 1
673. Infection from #19 goes into which nodes: SUBMANDIBULAR
674. Teeth position during swallowing: MAXIMAL INTERCUSPITATION
675. A patient with a peg tooth in MX arch, which tooth is it: LATERAL INCISOR
676. A patient is missing a tooth in MN among posterior teeth, which tooth is most likely to be missing: 3rd MOLAR
677. Cells seen in acute inflammation: NEUTROPHILS
678. Mandible formation: INTERMEMBRANOUS (BODY), ENDOCHONDRAL (CONDYLE) → BICE
679. Postganglionic sympathetic neurotransmitter for sweat glands: ACH
680. Which organ is a sympathetic receptor: ADRENAL MEDULLA
681. Location of the thoracic duct: POSTERIOR TO ESOPHAGUS, MEDIAL TO KIDNEYS, LATERAL & POSTERIOR TO TRACHEA
682. Dimorphism: YEAST & HYPHAE (MOLD)
683. Which cerebral lobe is located in the middle cranial fossa: TEMPORAL LOBE
684. Drop in O2 pressure is detected by: CAROTID BODY
685. Stimulation of carotid sinus leads to: DROP IN BLOOD PRESSURE
686. Which one is not an organelle: LIPID DROPLETS
687. Innervation of the upper lip: BUCCAL BRANCH OF FACIAL N., INFRAORBITAL N.
47
688. Voluntary movements in muscles, which tract: CORTICOSPINAL
690. Which interaction keeps the cell membrane intact: HYDROPHOBIC BONDS
691. Why a diabetic patient (type 1) was able to reduce the amount of injected insulin after he decided to work out more: INCREASED
INSULIN SENSITIVITY
692. Which one is not in the posterior wall of axilla: SERRATUS ANTERIOR
693. Troponin changes the position of: TROPOMYOSIN
694. Connective tissue that covers only one muscle fiber: ENDOMYSIUM
695. Most abundant papilla of the tongue: FILIFORM
696. Which one is not derived from ectoderm: ALVEOLAR BONE
697. Body of the hyoid is derived from which embryonic cartilage: SECOND CARTILAGE
698. What is the nerve in pericardium: PHRENIC NERVE
699. What are Fordyce granules: ECTOPIC SEBACEOUS GLANDS IN THE MUCOSA OF THE CHEEK
700. The cause of diabetes mellitus: AUTOIMMUNE / DECREASED SENSITIVITY TO INSULIN RECEPTORS
48
701. Dull pain in the pulp: C FIBERS
702. Anterior pituitary deficiency will cause: HYPOGONADISM, ADDISON’S DISEASE, MYXEDEMA
703. Deeply stained granules in the oral mucosa are: KERATOHYALIN GRANULES
Keratohyalin is a protein structure found in granules in the stratum granulosum of the epidermis, which may be involved in
keratinization, and in Hassall's corpuscles in the thymus. In H&E stained sections, they are large deeply stained granules found in the
cytoplasm of epithelial cells in keratinized oral mucosa.
704. In fluorosis, where can excessive fluoride be seen: BONES, TEETH, CARTILAGE, NAILS
705. Junctional epithelium is made out of: REDUCED ENAMEL EPITHELIUM
706. Apical 1/3 in the root, few, more than one, communication between PDL & pulp: ACCESSORY CANALS
707. Ligamentum teres is a remnant of: UMBILICAL VEIN
708. Hematoma after injection in the area of MX 1st molar is due to: INSERTION OF THE NEEDLE INTO PTERYGOID PLEXUS
709. Immunity from the mother to the fetus: NATURAL PASSIVE
Natural
- active being sick
- passive breastfeeding
Artificial
- active vaccination with attenuated virus or toxoid
- passive antitoxin
49
716. Guiding cusps: NON-FUNCTIONAL CUSPS
Rosacea is a long-term skin condition that typically affects the face. It results in redness, pimples, swelling, and small and superficial
dilated blood vessels. Often the nose, cheeks, forehead, and chin are most involved. A red enlarged nose may occur in severe disease,
a condition known as rhinophyma. The cause of rosacea is unknown. Risk factors include a family history of the condition. Factors that
may potentially worsen the condition include heat, exercise, sunlight, cold, spicy food, alcohol, menopause, psychological stress, or
steroid cream on the face. Diagnosis is based on symptoms. While not curable, treatment usually improves symptoms. Treatment is
typically with metronidazole, doxycycline, or tetracycline. When the eyes are affected azithromycin eye drops may help. Dermabrasion
or laser surgery may also be used. The use of sunscreen is typically recommended. Rosacea affects somewhere between 1-10% of
people. Those affected are most often 30-50 years old and female. Caucasians are more frequently affected.
Pitting edema: observable swelling of body tissues due to fluid accumulation that may be demonstrated by applying pressure to the
swollen area (such as by depressing the skin with a finger). Low protein levels in the blood caused by malnutrition, kidney and liver
disease can also cause edema. The proteins help to hold water inside the blood vessels so fluid does not leak out into the tissues. If a
blood protein, called albumin, gets too low, fluid leaks out the blood vessels and edema occurs, especially in the feet, ankles and lower
legs.
721. The difference between facilitated transport and active transport: USE OF ATP
722. What is the ration of the blood circulating in capillaries and aorta: THE SAME
723. What is the second messenger for glycogen: cAMP
724. Proximal view of MN 1st molar: RHOMBOID
725. Which enzyme converts glucose to glucose-6-phosphate: HEXOKINASE
726. What is the pace setting enzyme for glycolysis: PHOSPHOFRUKTOKINASE
727. Asthma medication: B2-ADRENERGIC AGONISTS
728. Urinary tract cancer: SMOKING CIGARETTES (carcinogens from cigarettes get excreted through the urine)
50
729. A patient with hypertension is not willing to take his premedication, he is insisting on having the dental procedure done, what
should you do: CANCEL THE APPOINTMENT, PRIORITIZING THE OVERALL HEALTH OF THE PATIENT TO HIS DENTAL HEALTH
730. You recommended a pregnant patient to have her teeth cleaning done, why: SHE IS AT RISK FOR PREGNANCY GINGIVITIS /
BLEEDING GUMS
731. She is 6 weeks pregnant, how long will you wait to do a procedure: 6 MORE WEEKS (TILL THE 12th WEEK)
732. Junction of proximal ridge and cusp ridge makes: OCCLUSAL TABLE
733. Cervical cross-section of MN lateral incisor: OVAL, FLATTENED M-D
734. Cervical cross-section of MX central incisor: TRIANGULAR
735. Middle cross-section of the root of MX central incisor: TRIANGULAR
736. Proximal outline shape of central incisors: TRIANGULAR
737. Height of contour of MX central incisor: CERVICAL THIRD
738. A 16-year-old patient with 2nd primary molar, what is the reason: AGENESIS
739. Mamelons in a 17-year-old patient due to: MALOCCLUSION
740. Tooth that most likely has two canals in the medial root: MN 1st MOLAR
741. Occlusal surface with grooves in the shape of “Y” is seen in: MN 2nd PREMOLAR
742. “Y” shape is formed by: 2 LINGUAL & 1 FACIAL CUSPS OF MN 2nd PREMOLAR
743. TMJ clicking is a result of damage to which ligament: COLLATERAL
744. Root in primary MN 1st molar that is longer & wider, with flattened apex: MESIAL ROOT
745. Only tooth with lingual surface as the widest: MX 1st MOLAR
746. Excessive sympathetic stimulation inhibits: PERISTALSIS
747. Laterotrusive movement, MN canine contacts: MX CANINE
748. Bucco-lingual space in the interproximal area: COL
Col: a craterlike area of the interproximal oral mucosa joining the lingual and
buccal interdental papillae.
749. If the mandibule was moved to the right, the contact that occurs on the left is called: NON-WORKING INTERFERENCE
750. Adenosine movement via: ADP/ATP TRANSLOCASE
751. All body cavities are covered with: MESOTHELIUM (SIMPLE SQUAMOUS)
Mesothelium: lines the pleural, peritoneal & pericardial cavities. It is composed of monolayer of epithelial-like cells on a thin basal
membrane and subserosal connective tissue and blood vessels.
Simple squamous epithelium.
752. During laterotrusive movement, the MN canine moves distally or medially to the MX canine: DISTALLY
753. Outlet facet on mesiolingual cusp by which movement: LATEROTRUSIVE
754. Tetracycline stain is due to defect in mutation: MISSENSE
A ganglioside is a molecule composed of a glycosphingolipid with one or more sialic acids linked on the sugar chain. Tay-Sachs disease
(TSD) is a fatal genetic disorder, MC occurring in children, that results in progressive destruction of the nervous system. Tay-Sachs is
caused by the absence of a vital enzyme called hexosaminidase-A (Hex-A). Without it, a lipid called GM2 ganglioside accumulates
abnormally in cells, especially in the nerve cells of the brain. This ongoing accumulation causes progressive damage to the cells.
Hyaluronic acid is highly concentrated inside the eyeball. The fluid inside the eye called the vitreous humor is composed almost
completely of hyaluronic acid. The HA gives the fluid inside the eye a viscous gel like property. This gel acts as a shock absorber for the
eye and also serves to transport nutrients into the eye. HA has been directly injected into the eye during procedures to help maintain
the shape of the eye during surgery. It has been said that after the 5 th decade of life, our eyes stop producing the much-needed
hyaluronic acid.
766. What is found in the inner membrane of hepatitis virus: MATRIX PROTEIN
767. Bronchial tree sequence: TRACHEA → MAIN (PRIMARY, R & L) BRONCHI → LOBAR (2nd) BRONCHI → SEGMENTAL (3rd)
BRONCHI → INTERLOBULAR BRONCHI → LOBULAR BRONCHIOLES → TERMINAL BRONCHIOLE (they lose cartilage) →
RESPIRATORY BRONCHIOLE → ALVEOLI
768. Erupts after the last succedaneous tooth: 2nd & 3rd MOLARS
769. Fumarase, what kind of reaction: HYDRATION
52
• DNA fingerprinting is a technique that simultaneously detects lots of minisatellites in the genome to produce a pattern unique
to an individual - this is a DNA fingerprint.
• The probability of having two people with the same DNA fingerprint that are not identical twins is very small.
53
780. What is the reason for refractory period: SODIUM CHANNEL INACTIVATION & DELAYED CLOSING OF POTASSIUM CHANNEL
Refractory period is the amount of time it takes for an excitable membrane to be ready for a second stimulus once it returns to its
resting state following an excitation. Absolute refractory period corresponds to depolarization and repolarization, whereas relative
refractory period corresponds to hyperpolarization.
Each IgG molecule consists of two heavy chains and two light chains. The two heavy chains are linked to each other by disulfide bonds
and each heavy chain is linked to a light chain by a disulfide bond. In any given immunoglobulin molecule, the two heavy chains and
the two light chains are identical, giving an antibody molecule two identical antigen-binding sites, and thus the ability to bind
simultaneously to two identical structures.
Fab – variable region: defines the specific target for the antibody
Fc – constant region: the same for each species
798. What is formed from neural crest cells: MELANOCYTES, SCHWANN CELLS, CHROMAFFINE CELLS OF ADRENAL MEDULLA
In order to activate chromaffin cells, the splanchnic nerve of the sympathetic nervous system releases acetylcholine, which then binds
to nicotinic acetylcholine receptors on the adrenal medulla. This causes the release of catecholamines. The chromaffin cells release
catecholamines: ~80% of adrenaline and ~20% of noradrenaline into systemic circulation for systemic effects on multiple organs
(similarly to secretory neurones of the hypothalamus) and can also send paracrine signals.
799. What is Bowman’s capsule: DOUBLE LAYER; PARIETAL – SIMPLE SQUAMOUS, VISCERAL – PODOCYTES
800. Superior orbital fissure: GREATER AND LESSER WING OF THE SPHENOID BONE
801. Which part of nephron takes up the most ATP: PROXIMAL CONVOLUTED TUBULE
54
802. Carboxyhemoglobin is due to: CARBON MONOXIDE BINDING TO HEMOGLOBIN
803. What passes between palatoglossus and palatopharyngeus: PALATINE TONSILS, TONSILLAR BRANCH & ASCENDING
PHARYNGEAL BRANCH OF FACIAL ARTERY, STYLOPHARYNGEUS, GLOSSOPHARYNGEAL NERVE
A syndesmosis is a slightly movable fibrous joint in which bones are joined together by connective tissue. Examples include the distal
tibiofibular joint as well as the radioulnar joint. Injuries to the ankle syndesmosis are commonly known as a "high ankle sprain".
\\
807. What runs along external carotid artery: SUPERFICIAL LNs, EXTERNAL JUGULAR VEIN, VAGUS NERVE
55
EJV runs with great auricular n., superficial cervical LN
IJV runs with CN X (vagus), ICA, ECA, CN XI (accessory), superior deep cervical LN
ECA runs with CN X (vagus), ICA, retromandibular vein, great auricular n.
Glossopharyngeal and hypoglossal pass between IJV and ICA
Carotid sheath:
- CCA (divides into ECA & ICA inside the sheath)
- IJV
- CN X
Flow rate: the volume of fluid which passes per unit time
Flow velocity: how fast
56
820. Chlamydia causes infection of: GENITALS AND EYES
821. Insufficient ADH secretion causes: DIABETES INSIPIDUS
Diabetes insipidus: results from insufficient production of the antidiuretic hormone (ADH), a hormone that helps the kidneys and body
conserve the correct amount of water. Normally, the antidiuretic hormone controls the kidneys' output of urine. It is secreted by the
hypothalamus, stored in the pituitary gland, and then released into the bloodstream. ADH is secreted to decrease the amount of urine
output so that dehydration does not occur. Diabetes insipidus, however, causes excessive production of very diluted urine and excessive
thirst. The disease is categorized into groups:
- central diabetes insipidus - an insufficient production or secretion of ADH; can be a result of damage to the hypothalamus or pituitary
gland caused by head injuries, genetic disorders, and other diseases,
- nephrogenic diabetes insipidus - a lack of kidney response to normal levels of ADH: can be caused by drugs or chronic disorders, such
as kidney failure, sickle cell disease, or polycystic kidney disease.
822. Splanchnic nerve: PS FIBERS TO TRANSVERSE COLON (DISTAL TO SPLENIC FLEXURE), DESCENDING COLON, SIGMOID COLON,
RECTUM (S2-S4); S FIBERS TO FOREGUT & MIDGUT
823. Aldosterone is partially responsible for: REABSORPTION OF WATER IN THE COLLECTING DUCT
824. Partial pressure of O2 in Himalayas if atmospheric pressure is 250: 50% (20% from 250)
825. Young permanent tooth with pulp horns: CENTRAL INCISOR
57
826. Does hepatitis C have a carrier: YES
827. Pseudostratified lining came out during extraction of MX molar, where is the lining from: MX ANTRUM/SINUS
828. Most common vaccine in the US: DPT
829. Why is a non-alive vaccine better than alive vaccine for polio: TO INHIBIT REACTIVATION IN LIVE
An inactivated vaccine works when the immune system responds to a piece of a bacteria or virus or to a toxin produced by the germ.
Live “attenuated” vaccines mean they have been changed such that they do not cause disease. They grow inside the vaccinated person
until the immune system recognizes the bacteria or virus and has the appropriate response, similar to a natural infection.
830. What stops the immune reaction in the tissues: SUPRESSOR T CELLS
831. Dentin composition: 70% INORGANIC, 20% ORGANIC, 10% WATER
832. Purely serous glands: PAROTID GLAND & VON EBNER GLANDS
833. Hepatitis C patient, you do FNAC (Fine Needle Aspiration Cytology) of the liver and find excess of: COLLAGEN, HEPATOCYTES,
NEUTROPHILS
834. A young guy comes to the dental office and complains: “my girlfriend says, that my mouth stinks”. He is obese, diabetic (t. II),
alcoholic. The reason for his bad breath is most likely: KETOACIDOSIS
835. What maintains the tissue & water balance: GLYCOSAMINOGLYCANS
836. Eosinophilia due to: PARASITIC INFECTION
837. Patient underwent canine RCT and there is an infection in the same tooth after 5 years. What can be the cause: PRESENCE OF
AN ACCESSORY ROOT CANAL
838. Gomphosis: TOOTH & SOCKET
839. Basal cell carcinoma: UPPER FACE, NOSE; INVOLVES SUN-EXPOSED AREAS
58
Legionnaire’s (Legionellosis) is caused by Legionella Pneumophila, a bacterium usually found in streams, rivers and lakes. There are
two basic forms of the infection:
- Legionnaire’s Disease: a serious form of the Legionellosis infection. Symptoms include chills, fever, a cough, tiredness and fatigue,
headache and muscle ache and decreased appetite. Distinguishing Legionnaire’s Disease can be difficult, as chest scans and X-rays
taken from patients can often present as pneumonia. Additional tests will be required for a patient to be firmly diagnosed with
Legionnaire’s Disease.
- Pontiac Fever: a milder form of Legionellosis does not include pneumonia-like symptoms. Symptoms include muscle ache and fever.
Patients suffering from Pontiac Fever typically recover within 2-5 days with no need for medical treatment. The onset of Pontiac fever
typically occurs within 2 hours and up to 2 days following exposure and Legionnaire’s Disease within 2-10 days of exposure.
845. At what age do MN roots formation ends: PRIMARY → 1-1,5 YEARS AFTER ERUPTION, PERMANENT → 2-3 YEARS AFTER
ERUPTION
846. Keloid is formed by: COLLAGEN
Keloid, also known as keloid disorder and keloidal scar, is the formation of a type of scar which, depending on its maturity, is composed
mainly of either type III (early) or type I (late) collagen. It is a result of an overgrowth of granulation tissue (collagen type 3) at the site
of a healed skin injury which is then slowly replaced by collagen type I. Keloids are firm, rubbery lesions or shiny, fibrous nodules, and
can vary from pink to the color of the person's skin or red to dark brown in color.
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857. The root of the lung is supplied by: BRONCHIAL A., V. & N.
859. Why don’t we prescribe penicillin with erythromycin: THEY BOTH ANTAGONIZE THEIR EFFECTS
Penicillin inhibits the last step of cell wall synthesis and erythromycin will inhibit cell division (no more cell synthesis), so penicillin
loses its effect. Penicillin acts on cells that still multiply, and erythromycin prevents that.
863. After extraction of MX 1st & 2nd molar patent came back with a hematoma at the site of middle insertion, why: POSTERIOR
SUPERIOR NERVE HEMATOMA
864. Which cell is not present in the periosteum: OSTEOCYTE
865. MN 1st molar, where is the 4th canal: DISTAL ROOT
60
866. Normal flora of the oropharynx: STREPTOCOCCUS MUTANS & STREPTOCOCCUS PYOGENES (both are present, but S. pyogenes
colonize only 1-5% of healthy individuals)
Skin S. epidermidis
Nose S. epidermidis, S. aureus
Oropharynx Viridans
Plaque S. mutans
Vagina Lactobacillus, S. saprophyticus, colonized by E. coli
867. All infrahyoid muscles depress the larynx, except: THYROHYOID MUSCLE
868. 8 M urea denaturates proteins by CARBAMYLATION which breaks HYDROPHOBIC BONDS in the tertiary structure.
Dental Decks:
869. Embryonic origin of the external acoustic meatus: 1st PHARYNGEAL CLEFT
870. Atherosclerosis: INTIMA OF THE ARTERIES
871. Pittng seen in: HEART FAILURE, VARICOSE VEINS, INSECT BITES, THROMBOPHLEBITIS
872. A lady had an accident a few days before, she came to your office complaining about her loose teeth (both MX central
incisors), she has a black pigmentation around her left eye.
- which fibers were not responsible for the teeth to become loose: INTERRADICULAR
- what can be the reason for a radiolucent structure between the teeth: INCISIVE FORAMEN
- what formed around her eye: ECCHYMOSIS (escape of blood into the tissues from ruptured blood vessels)
- when could her accident happened: 2-5 DAYS AGO
61
876. PNET and Ewing’s sarcoma account of: PRIMARY MALIGNANT TUMOR
Multiple myeloma is a cancer of plasma cells. Often, no symptoms are noticed initially. When advanced, bone pain, bleeding, frequent
infections, and anemia may occur. Complications may include amyloidosis. The cause is unknown. Risk factors include drinking alcohol,
obesity, radiation exposure, family history, and certain chemicals. The underlying mechanism involves abnormal plasma cells producing
abnormal antibodies which can cause kidney problems and overly thick blood. The plasma cells can also form a mass in the bone
marrow or soft tissue. When only one mass is present, it is known as a plasmacytoma while more than one is known as multiple
myeloma. Multiple myeloma is diagnosed based on blood or urine tests finding abnormal antibodies, bone marrow biopsy finding
cancerous plasma cells, and medical imaging finding bone lesions. Another common finding is high blood calcium levels.
Multiple myeloma is considered treatable, but generally incurable. Remissions may be brought about with steroids, chemotherapy,
thalidomide or lenalidomide, and stem cell transplant. Bisphosphonates and radiation therapy are sometimes used to reduce pain from
bone lesions.
In the United States, it develops in 6.5 per 100,000 people per year and 0.7% of people are affected at some point in their lives. It usually
occurs around the age of 61 and is more common in men. Without treatment, typical survival is seven months. With current treatments,
survival is usually 4–5 years. This gives a five-year survival rate around 49%.
878. A woman was killed on the beach, she has lacerated neck and a knife puncture 12 cm deep to the left of T4 vertebra.
- what organ is most likely to be injured: LUNG/AORTA
- laboratory investigation proved she had multiple nodular cirrhosis, what is the cause: ALCOHOLISM
- she had an infraorbital fracture involving the left canthus of the eye, bone: ZYGOMATIC
879. Autoimmune: DIABETES TYPE I
880. What nerve for muscles responsible for circumduction: AXILLARY NERVE (deltoid muscle)
62
884. Cause protrusion of the cricoid cartilage: PREVERTEBRAL LAYER OF DEEP CERVICAL FASCIA
First Aid: the prevertebral layer of deep cervical fascia is why the thyroid moves with laryngeal movements.
885. Sensory innervation of the upper lip in the middle: MAXILLARY → INFRAORBITAL → SUPERIOR LABIAL
886. Bacteria that cause a foul odor: ACTINOMYCOSIS
887. Filamentous formation on the angle of the mandible: ACTINOMYCETES
888. Crown with mesial concavity: MX 1st PREMOLAR (also MX canine)
889. Mesial furcation in the upper posterior teeth: MESIAL & DISTAL IN MX 1st PREMOLAR; BUCCAL, MESIAL & DISTAL IN MX
MOLARS
890. Maxillary furcations: MESIAL, DISTAL, BUCCAL
891. What is probably a radiolucent irregular line in the outer canthus: SUTURE
892. Dead child, what is the counter bone (the bone on the opposite site of the impact → left eye and it’s surroundings; bone
around the orbit): PARIETAL BONE
893. Why does the crown of a MN canine looks longer: CROWN LOOKS SLENDER DUE TO SMALL MESIODISTAL DIMENSION WHEN
COMPARED TO MX CANINE
894. Increase in 2,3-bisphosphoglycerate causes: THE AFFINITY OF Hb TO O2
Cirrhosis & portal hypertension → hematemesis & bleeding from esophageal varices → hemorrhage → hypovolemic shock (so liver
cirrhosis is the reason for, not a sequelae of, shock).
63
907. Taste sensation to circumvallate papillae: GLOSSOPHARYNGEAL NERVE
908. Contact areas over a period of time: GET BROADER
909. Height of contour in MX molars, facially: CERVICAL 1/3
910. Primary MN molar, cervical ridge: PROMINENT ON MN 1st PRIMARY MOLAR
911. Primary teeth, cervical ridges are prominent on: FACIAL AND LINGUAL SURFACES
912. MN lateral incisor vs. MN central incisor
MN lateral incisor:
- is wider M-D
- D-L twist of the incisal edge seen from the M (& occlusal)
- root is tipped to the D
- D crown tilt
913. Pulp chamber is triangular, becomes ovoid in mid-root: MAXILLARY CENTRAL INCISOR
914. Ksp solubility constant of ions – how does ions precipitate: PRODUCT CONCENTRATION OF IONS
Precipitation occurs when cations and anions are combined in aqueous solution to form insoluble ionic solid.
915. Primary 1st molar, facial surface has no developmental groove: TRUE
916. Afferent fibers involved with the gag reflex: CN IX
917. Pupillary reflex, which nerve and which muscle is involved when entering a dark room: CN II & CN III, DILATOR PAPILLAE
1. Left direct pupillary reflex is the left pupil's response to light entering the left eye.
2. Left consensual pupillary reflex is the left pupil's indirect response to light entering the right eye, the contralateral eye.
3. Right direct pupillary reflex is the right pupil's response to light entering the right eye.
4. Right consensual pupillary reflex is the right pupil's indirect response to light entering the left eye, the contralateral eye.
918. Number of pulp horns and canals in MN 1st molar: 5 HORNS, 3 CANALS (sometimes 4 canals)
919. Asthma is characterized by: EPISODIC AIRWAY OBSTRUCTION, BRONCHI CONSTRICTION
920. Fusion only by the cementum: CONCRESCENCE
921. Acellular cementum formed at: CERVICAL 1/3
922. Cellular cementum formed at: APICAL PORTION
64
923. Secondary cementum has all except: BLOOD
924. Hereditary defect causes improper formation of: ENAMEL
925. Necessary for formation of the bone & the periosteum: VITAMIN C & D
926. Collagen: TROPOELASTIN IS NOT PRESENT
Collagen and elastin are similar in that they contain proline residues and are composed of approximately 1/3 glycine. However, elastin
differs from collagen because it contains very few hydroxyproline molecules, and completely lacks hydroxylysine. Remember that
hydroxyproline or hydroxylysine commonly precede glycine in collagen fibers.
Glycine and proline = components of collagen and elastin.
927. A doctor develops urticaria (hives) after donning latex gloves – which reaction is it: TYPE 1
Atopic allergies are common type I HS reactions that have a strong genetic predisposition for excessive IgE production. Clinical
manifestations include asthma, edema, and erythema (“wheal and flare”), and urticaria (hives). Common allergens include pollens,
animal danders, foods (shellfish and peanuts), drugs (penicillin), bee venom, and latex.
Contact allergy is due to inadequate washing during manufacture, which results in the retention of water-soluble proteins that cause
allergic reactions in susceptible people.
Angioedema is the swelling of deep dermis, subcutaneous, or submucosal tissue due to vascular leakage. Acute episodes often involve
the lip, eyes, and face; however, angioedema may affect other parts of body, including respiratory and GI mucosa. Laryngeal swelling
can be life-threatening.
Mast cells are the primary effector cells in urticaria and in many cases of angioedema. These cells are widely distributed in the skin,
mucosa, and other areas of the body, and have high-affinity IgE receptors. Mast cell degranulation leads to the rapid release of various
inflammatory mediators, such as histamine, leukotrienes and prostaglandins, which, in turn, cause vasodilation and leakage of plasma
in and below the skin. There is also a more delayed (4–8 hour) secretion of inflammatory cytokines (e.g., TNF, Il-4 and Il-5) that
potentially leads to further inflammatory responses and longer-lasting lesions.
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934. Vestibular swelling epithelium: NONKERATINIZED STRATIFIED SQUAMOUS
935. After endodontic treatment, biopsy was done showing resorbed bone and a lot of neutrophils. Pain occurs again, what is the
reason: ABSCESS
936. A woman with leiomyoma. Tongue with a swelling, lumen lined with epithelium: CYST
937. Cells of the basement membrane of seminiferous tubules: SPERMATOGONIA
Complementarity-determining regions (CDRs) are part of the variable chains in immunoglobulins and T cell receptors, generated by
B-cells and T-cells respectively, where these molecules bind to their specific antigen. A set of CDRs constitutes a paratope. As the most
variable parts of the molecules, CDRs are crucial to the diversity of antigen specificities generated by lymphocytes.
Above: sketch of an antibody with the variable domains (blue) and CDRs (light blue, part of the variable domains):
940. MHC-1 binds: CD8 Th CELLS (smaller – 1 – MHC with bigger – 8 – CD)
941. MHC-2 binds: CD4 Th CELLS (bigger – 2 – MHC with smaller – 4 – CD)
942. Why do CD8 lymphocytes respond to antigen associated with MHC-1
The function of the class I MHC is to display intracellular proteins to cytotoxic T cells (CTLs); however, class I MHC can als o present
peptides generated from exogenous proteins, in a process known as cross-presentation.
A normal cell will display peptides from normal cellular protein turnover on its class I MHC, and CTLs will not be activated in response
to them due to central and peripheral tolerance mechanisms; when a cell expresses foreign proteins, such as after viral infection, a
fraction of the class I MHC will display these peptides on the cell surface; consequently, CTLs specific for the MHC:peptide complex will
recognize and kill presenting cells.
943. For immunization, what do you inject in a toxigenic infection: TOXOID (antitoxin would be used in treatment)
944. What is incorporated in the cell membrane of nerve cells: SPHINGOMYELIN, WHICH ALSO CONTAINS LECITHIN
Sphingomyelin (SPH) is a type of sphingolipid found in animal cell membranes, especially in the membranous myelin sheath that
surrounds some axons. It usually consists of phosphocholine and ceramide, or a phosphoethanolamine head group; therefore,
sphingomyelins can also be classified as sphingophospholipids. In humans, SPH represents ~85% of all sphingolipids, and typically make
up 10–20 mol % of plasma membrane lipids.
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945. Action of norepinephrine on heart rate: HR
946. Action of norepinephrine on the force of contraction: the force
947. Action of beta blokers on the heart and respiration: BRONCHOCONSTRICTION, NEGATIVE INOTROPY, NEGATIVE
CHRONOTROPY
Since its going to act on B receptors, it is going to reverse the effect of what they usually do (B1 which increases heart rate will cause it
to decrease, B2 which causes dilation of bronchioles, smooth muscles, increase glucose hepatic uptake - all will be decreased)
Definition Affects the force of contraction Affects the heart rate Affects conduction velocity
chrono = time
Origin in- = fibre / sinew dromos = running, a course, a race
tropos = a turn
Junction between epithelium and lamina propria is more visible than between lamina propria and submucosa.
67
951. Hemidesmosomes are present in: THE BASAL LAMINA / STRATUM BASALE
952. Intracellular connection between two cells that allows them to communicate: GAP JUNCTION (nexus, macula communicans)
953. Which cell-cell junction is the most resistant passage of communication between cells: ZONULA OCCLUDENS (thight junction)
954. Which nerve won’t be directly affected if there was an infection in cavernous sinus: OPTIC NERVE
Affected first would be CN VI (abducens; it’s in the middle of cavernous sinus, whereas the rest are on the periphery).
Parkinson disease: TRAP → tremor (at rest), rigidity, akinesia, postural instability
957. When the dentin become sclerotic: AFTER INJURY / WITH AGE
958. Type I collagen is a main constituent of all of the above except: ENAMEL
959. Collagen structure: TRIPLE HELIX
Each helix is left-handed, makes 30% of the whole-body protein content, quaternary structure stabilized by hydrogen bonds,
has 3.3 residues per turn, Gly-Pro-X or Gly-X-Hyp.
Gly: 1/3 (every third AA is glycine)
Pro/Hyp: 1/6
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962. Myasthenia gravis testlet, dysphagia – problem with which muscles: PALATOGLOSSUS, STYLOPHARYNGEUS, ORBICULARIS ORIS,
PALATOPHARYNGEUS, TENSOR VELI PALATINI, LATERAL PTERYGOID MUSCLE
963. SABE is a sequel (an after effect of a disease) of: RHEUMATIC FEVER
965. Adenoids removed due to upper airway obstruction, present where: NASOPHARYNX OPENING AT CHOANCHA
966. Patient with night bruxism, which muscle is painful: MASSETER (or temporalis)
967. More abundant SER with Golgi apparatus is found: IN CELLS PRODUCING STEROIDS
968. Testlet with a patient with Parkinsons disease: while performing RCT on MX 2 nd molar the patient moved and the dentist
penetrated the cheek with a handpiece, pulsating blood flow was seen, which structure was involved: BUCCAL ARTERY
969. Nerve exiting from stylomastoid foramen was damaged, which muscles were affected: ORBICULARIS ORIS (facial expression
muscles due to CN VII injury)
970. A broad facet is present on the outer side of MX lingual surface on the left side; caused due to: LEFT LATEROTRUSIVE
MOVEMENT (WORKING SIDE)
971. Cusp height in a cast restoration is least affected by: INTERCONDYLAR DISTANCE
972. The the condylar guidance: THE CUSP HEIGHT
973. Mechanism of filling the lungs with air: INTRATHORACIC PRESSURE , SO THE AIR FLOWS INTO THE LUNGS
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974. Shock and cor pulmonale: GI BLEEDING (???)
975. Ligament active during protrusion: STYLOMANDIBULAR
976. Ligament active while yawning: OBLIQUE FIBERS OF TM LIGAMENT
977. Which ligaments prevent protrusion, excessive opening, yawing
Capsular ligament:
- surrounds the entire joint, retains the synovial fluid
- resist medial, lateral or inferior forces
- well innervated → proprioceptive feedback of the joint (its’ position and movement)
TM ligament (lateral):
- the main stabilizing ligament of the TMJ
- from lateral surface of the zygomatic arch and a tubercle on its lower border, directed obliquely downward and backward to insert
into the posterior border and lateral surface of the neck of the mandible
- restricts downward and posterior movement and guides the forward motion of the condyle during opening
- outer oblique portion → excessive drooping of the condyle, limits mouth opening
- inner horizontal portion → limits posterior movement
Sphenomandibular ligament:
- accessory ligament
- attached to the lingula of the mandible
- does not have any significant limiting effects
Stylomandibular ligament:
- accessory ligaments
- attached at the angle of the mandible
- limits excessive protrusive movements of the mandible
978. Which component of adrenal gland had steroid producing fat cells in it: ZONA RETICULARIS
985. Contact point on the mesial of MX lateral incisor: JUNCTION (between incisal 1/3 & middle 1/3)
986. Congenital missing tooth: MN 3rd molar > MX 3rd molar > MX lateral incisor > MN 2nd premolar
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987. Tooth difficult to restore: MESIAL MX 1st PREMOLAR & DISTAL MX 1st MOLAR; PALATALLY MX LATERAL INCISOR
988. MX premolar, cusp offset to distal in table form: BUCCAL CUSP (MX 1st premolar)
989. MN incisors comprasion
Central: more symmetrical, minimal distal & mesial bulge of the crown, proximal contacts on the same level mesially & distally, smaller
than lateral incisor
Lateral: less symmetrical crown, obvious bulge of the crown, crown tilted distally, mesial proximal contact is more incisal, larger than
central incisor
990. Cusp height and fossa depth are not influenced by: INTERCONDYLAR DISTANCE
991. Primary teeth lack: MAMELONS & ROOT TRUNKS
992. Primary 1st molar has no groove on the buccal surface and has a groove on the lingual surface: TRUE
993. Primary molar below the plane of occlusion, the permanent tooth hasn’t erupted: ABSCENSE OF THE PERMANENT TOOTH BUD
994. Mesiolingual cusp of MX tooth & distobuccal cusp of MN tooth: MEDIOTRUSIVE MOVEMENT
ML cusp of MX molar & DB cusp of MN molar are in the cusp-fossa relationship. During mediotrusive movement, ML cusp of MX molar
→ DB groove & DB cusp of MN molar → ML cusp
995. Cross-bite, class III, MN lateral incisor contacts: MX LATERAL INCISOR CONTACTS MN LATERAL & CANINE ON RETRUSION IN A
CLASS III ANTERIOR CROSS-BITE (???)
996. Largest cusp of MX molars: ML FOR PERMANENT MX MOLARS; MB in primary (MB > ML > DB > DL)
997. Cusp of Carabelli: ML
998. Oblique ridge connects: ML TO DB CUSPS
999. Class V cavity from mesial to distal on MX 2nd molar, facial surface, where are the proximal contacts & height of
contour: MIDDLE THIRD & CERVICAL THIRD
What we need to take under consideration while rebuilding lost tissues in a class V cavity:
- proximal contacts on MX 2nd molar: MIDDLE THIRDS (both mesially & distally)
- height of contour on MX 2nd molar, facially: CERVICAL THIRD
1000. Accessory muscles of mastication that depress the mandible: SUPRAHYOID GROUP
1001. Condylar disc is stabilized by: SUPERIOR HEAD OF LATERAL PTERYGOID
1002. Are not functions of lateral pterygoid: ELEVATION & RETRUSION
1003. Anesthesia for MX 1st molar: POSTERIOR SUPERIOR ALVEOLAR NERVE, MIDDLE SUPERIOR ALVEOLAR NERVE, GREATER
PALATINE NERVE
1004. Innervation of MX 2nd molar, palatal: GREATER PALATINE NERVE
1005. Pancreas & liver are affected by: HEMOCHROMATOSIS (occurs in the bone marrow, spleen & liver)
This build-up of iron can cause unpleasant symptoms. If it isn't treated, this can damage parts of the body such as the liver, joints,
pancreas and heart. Haemochromatosis most often affects people of white north European background and is particularly common in
countries where lots of people have a Celtic background, such as Ireland, Scotland and Wales.
Anthracosis: accumulation of carbon in the lungs due to repeated exposure to air pollution or inhalation of smoke or coal dust particles.
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1018. Death due to infraction after 24h: COAGULATION NECROSIS (not sure about the logic of that answer, check #264)
Evolution of MI
1st day: coagulative necrosis within the first 24h leads to release of contents of necrotic cells into the bloodstream, beginning of
neutrophil emigration.
2-4 days: neutrophil emigration, the muscle shows an extensive coagulative necrosis
5-10 days: macrophages & neutrophils
7 weeks: infract healed by organization
Acute respiratory distress syndrome (ARDS) is a rapidly progressive disease occurring in critically ill patients. The main complication in
ARDS is that fluid leaks into the lungs making breathing difficult or impossible.
1022. Articular disc develops from: 1st PHARYNGEAL ARCH → MECKEL’S CARTILAGE
1023. TMJ develops from: 2nd PHARYNGEAL ARCH → REICHERT’S CARTILAGE
1024. Thymus, origin: 3rd PHARYNGEAL POUCH
1025. Respiratory center characteristics: SQUAMOUS EPITHELIUM; LOCATED IN THE BRAINSTEM, PONS & MEDULLA; 4 GROUPS:
INSPIRATORY, EXPIRATORY, PNEUMOTAXIC, APNEUSTIC
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1026. Parathyroid blood supply: INFERIOR THYROID ARTERY
1027. Lesion derived from epithelial cells: BONE, DENTIN, CEMENTUM, PDL, ENAMEL
1028. Receptor of salt: IONIC RECEPTOR
1029. Pyrimidine dimer is broken down by which enzyme: EXONUCLEASE
1030. Cancer do not involve: DYSPLASIA
1031. Bonds in an alpha helix conformation in a protein chain: HYDROGEN BOND
1032. Biotin: PYRUVATE CARBOXYLASE; FA SYNTHESIS
1037. Submental lymph nodes collect the lymph from which teeth: MANDIBULAR INCISORS
1038. Bacteria of the oral cavity: FERMENTATION
1039. Why polymyxin B is given only in fungal infections, not bacterial: BINDS TO ERGOSTEROL IN THE FUNGAL WALL
1040. Parasympathetic activity of the heart: HEART RATE
1041. Increased blood pressure, baroreceptor’s action will inhibit: SYMPATHETIC (AND INCREASE PARASYMPATHETIC)
74
1042. Medulla is sensitive to: HYDROGEN IONS
When PCO2 goes up, also increases H+ because CO2 + H2O forms carbonic acid, which then disassociates to H +.
1043. GTP action: ACTIVATE AND INACTIVATE ADENYL CYCLASE OR CLEAVED BY PROTEASOME
Mycelium is the vegetative part of a fungus or fungus-like bacterial colony, consisting of a mass of branching, thread-like hyphae.
1046. Lymph from anterior part of the skin drains to which superficial lymph nodes: SUBMANDIBULAR
The superficial lymph nodes of the head and neck receive lymph from the scalp, face and neck. They are arranged in a ring
shape; extending from underneath the chin, to the posterior aspect of the head. They ultimately drain into the deep lymph nodes.
• Occipital: There are usually between 1-3 occipital lymph nodes. They are located in the back of the head at the lateral border
of the trapezius muscle and collect lymph from the occipital area of the scalp.
• Mastoid: There are usually 2 mastoid lymph nodes, which are also called the post-auricular lymph nodes. They are located
posterior to the ear and lie on the insertion of the sternocleidomastoid muscle into the mastoid process. They collect lymph
from the posterior neck, upper ear and the back of the external auditory meatus (the ear canal).
• Pre-auricular: There are usually between 1-3 pre-auricular lymph nodes. They are located anterior to the auricle of the ear,
and collect lymph from the superficial areas of the face and temporal region.
• Parotid: The parotid lymph nodes are a small group of nodes located superficially to the parotid gland. They collect lymph
from the nose, the nasal cavity, the external acoustic meatus, the tympanic cavity and the lateral borders of the orbit. There
are also parotid lymph nodes deep to the parotid gland that drain the nasal cavities and the nasopharynx.
• Submental: These lymph nodes are located superficially to the mylohoid muscle. They collect lymph from the central lower lip,
the floor of the mouth and the apex of the tongue.
• Submandibular: There are usually between 3-6 submandibular nodes. They are located below the mandible in the
submandibular triangle and collect lymph from the cheeks, the lateral aspects of the nose, upper lip, lateral parts of the lower
lip, gums and the anterior tongue. They also receive lymph from the submental and facial lymph nodes.
• Facial: This group comprises the maxillary/infraorbital, buccinator and supramandibular lymph nodes. They collect lymph
from the mucous membranes of the nose and cheek, eyelids and conjunctiva.
• Superficial Cervical: The superficial cervical lymph nodes can be divided into the superficial anterior cervical nodes and the
posterior lateral superficial cervical lymph nodes. The anterior nodes lie close to the anterior jugular vein and collect lymph
from the superficial surfaces of the anterior neck. The posterior lateral nodes lie close to the external jugular vein and collect
lymph from superficial surfaces of the neck.
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1047. Secondary hypertension, renal cause: RENAL ARTERY STENOSIS
1048. Athrematous plaque in renal artery is caused by: ATHEROSCLEROSIS & CAUSE SECONDARY HYPERTENSION
If renal artery is occluded, you will get secondary HTN – kidney thinks blood volume is low, so it tries to compensate and you end up
with HTN.
An atheroma is a reversible accumulation of degenerative material in the inner layer of an artery wall. The material consists of
mostly macrophage cells, or debris, containing lipids, calcium and a variable amount of fibrous CT. The accumulated material forms a
swelling in the artery wall, which may intrude into the channel of the artery, narrowing it and restricting BF. Atheroma occurs
in atherosclerosis. In the context of heart or artery matters, atheromata are commonly referred to as atheromatous plaques. It is a
pathological condition found in most humans.
Toxoids are antigenic and non-toxic, most often prepared by treating toxins with formaldehyde.
They consist of weakened bacterial toxins that are no longer toxic but do induce antibodies production.
Vaccinia is a vaccine which is effective against small pox, but not effective against molluscum.
Small pox vaccine: live attenuated
Molluscum contaginosum: no vaccine
The recurrent laryngeal nerves control all intrinsic muscles of the larynx except for the cricothyroid muscle. These muscles act to open,
close, and adjust the tension of the vocal cords, and include the posterior cricoarytenoid muscles, the only muscle to open the vocal
cords.
MN 1st premolar: very prominent transverse ridge in the middle with mesial & distal fossae on the sides (“snake eyes”)
MX 1st molar: prominent oblique ridge
1056. Groove from mesial pit to central pit in MX molar: CENTRAL GROOVE
1057. Linguogingival groove is found in: MX LATERAL INCISOR
1058. Mandibular premolar: 3 PITS; 2nd PREMOLAR IS THE ONLY PREMOLAR WITH 5 DEVELOPMENTAL LOBES
1059. MN premolar, cusps from biggest to smallest: B > ML > DL
1060. Primary MX canine, outline of the facial surface: ARROW-SHAPED, PENTAGONAL
1061. Primary MX canine, outline of the incisal surface: DIAMOND
1062. Which primary tooth looks like a diamond: CANINE
1063. Which tooth has its long axis oriented most vertically: MX 1st PREMOLAR
1064. A tooth with three canals: MN MOLARS
1065. MN canine, 3 different configurations: 1 ROOT CANAL, 1 ROOT & 2 CANALS, 2 ROOTS & 2 CANALS
1066. Broken filling (ML cusp) of MX tooth, due to: MEDIOTRUSIVE MOVEMENT
1067. Tooth with one pulp horn: CANINE & MN 1st PREMOLAR
1068. Arbovirus: INSECT VECTOR
1069. Not transmitted by vectors: RICKETTSIA → Q FEVER
1070. Endogenous spread: E. COLI, STREPTOCOCCUS, ACTINOMYCES
1071. HIV associated diseases: NECROTIZING ULCERATIVE GINGIVITIS, PERIODONTAL DISEASE, CANDIDIASIS, HAIRY LEUKOPLAKIA,
KAPOSI SARCOMA
1072. HIV lymphoma: KAPOSI SARCOMA, PRIMARY LYMPHOMA OF THE BRAIN, NON-HODGKIN’S LYMPHOMA
1073. Denture stomatitis: CANDIDIASIS
1074. Cardiac problem, BP medication for: TACHYCARDIA (B-BLOCKERS)
1075. Sharpest incisal angle: MN CENTRAL INCISOR (MESIAL ANGLE)
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1076. Most concave side of MX canine: DISTAL
1077. Fungi in the mouth: CANDIDA
1078. Dimorphism in: HISTOPLASMOSIS, BLASTOMYCOSIS, COCCIDIOIDES, CANDIDA
1079. Action on macrophages on T-cells: MACROPHAGES EXPRESS MHC-2 & ATTRACT Th CELLS, WHICH IN TURN ACTIVATE
MACROPHAGES FOR PHAGOCYTOSIS TO RELEASE CYTOKINES
1080. Lower compartment of TMJ: INFERIOR AREA OF THE DISC & SUPERIOR AREA OF THE CONDYLE
1081. Sphenomandibular ligament (internal lateral ligament) origin from: SPINE OF THE SPHENOID BONE
Acellular Cellular
Formed first Formed second
Cervical 1/3 or 1/2 of the root Mainly in the apical 1/3
Does not contain cells Cementocytes in lacunae
Formed before the tooth reaches the occlusal plane Formed after the tooth reaches the occlusal plane
More calcified Less calcified
Sharpey’s fibers are the main component, which insert at Sharpey’s fibers occupy smaller portion, other fibers are
approximately right angles onto the root surface present, arranged parallel to the root surface
Rate of the development is faster Rate is slower
Incremental lines are wide apart Lines are closer
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1092. Bacteria inhibiting an inhibitor: ANTIBIOTIC RESISTANT (CONTAINS BETA-LACTAMASE)
Beta-lactamases are a family of enzymes involved in bacterial resistance to beta-lactam antibiotics. They act by breaking the beta-
lactam ring that allows penicillin-like antibiotics to work.
1093. Yellowish residue in the corner of the mouth: ANGULAR CHEILITIS / CHEILITIS EXFOLIATIVA
Silicosis (previously miner's phthisis, grinder's asthma, potter's rot and other occupation-related names) is a form of occupational lung
disease caused by inhalation of crystalline silica dust and is marked by inflammation and scarring in the form of nodular lesions in the
upper lobes of the lungs. It is a type of pneumoconiosis.
Silicosis (particularly the acute form) is characterized by shortness of breath, cough, fever, and cyanosis (bluish skin). It may often be
misdiagnosed as pulmonary edema (fluid in the lungs), pneumonia, or tuberculosis.
May lead to mesothelioma: is a type of cancer that develops from the thin layer of tissue that covers many of the internal organs.
Left side damage, left lateral pterygoid is not working. Movement of right lateral condyle causes mandible to move to left and hence
translation on right.
Polyene antimycotics, sometimes referred to as polyene antibiotics, are a class of antimicrobial polyene compounds that target fungi.
These polyene antimycotics are typically obtained from some species of Streptomyces bacteria. The polyenes bind to ergosterol in the
fungal cell membrane and thus weakens it, causing leakage of K+ and Na+ ions, which may contribute to fungal cell death. Amphotericin
B, nystatin, and natamycin are examples of polyene antimycotics. They are a subgroup of macrolides.
The structures usually stained are those that contain negative charges, such as the phosphate backbone of DNA in the cell nucleus and
ribosomes.
78
1113. ML developmental groove: MESIAL OF MN 1st PREMOLAR
1114. All of these microglia are present in CNS except: SCHWANN CELLS (in PNS)
1115. Oral contraceptives: LH DECREASES (prevent LH surge)
1116. Biosynthesis of cholesterol: SQUALENE
1117. Truncated (shorten by cutting off the top or the end) cells in the kidney: PROXIMAL CT
1118. Face formation: 1st & 2nd PHARYNGEAL ARCHES
1119. Size of the mouth is defined by: MX & MN PROCESSES UNION
1120. Which cross-section is the biggest in a FL diameter: MX CANINE
1121. Which enzyme is associated with phosphorylation of ADP at the substrate level: PRUVATE KINASE
1122. Which disease is most often characterized by hyphae growing in and around the vessels: MUCORMYCOSIS
1123. Preganglionic sympathetic fibers to the head have their cell bodies of origin in the: INTERMEDIOLATERAL HORNS OF THE
THORACIC SPINAL CORD
1124. Bifid tongue: LATERAL SWELLINGS FAIL TO FUSE
1125. Which are not standard AA: SELENOCYSTEINE, HYDROXYLYSINE & PYRROLYSINE
There are 20 standard AA that builds proteins. Among those, we have 9 essential & 11 nonessential AA.
1126. Class II occlusion, patient retruded, MX canine oppose which teeth: NO CONTACTS
Virchow's node, or Troisier's node, refers to carcinomatous involvement of the supraclavicular nodes at the junction of the thoracic
duct and the left subclavian vein. Usually, nodal enlargement is caused by metastatic gastric carcinoma, although supraclavicular nodal
involvement can also be seen in other gastrointestinal, thoracic, and pelvic cancers. Gastric cancers tend to metastasize to this region
by means of migration of tumor emboli through the thoracic duct, where subdiaphragmatic lymphatic drainage enters the venous
circulation in the left subclavian vein.
1131. ADH promotes the retention of water by: INCREASING AQUAPORINS IN COLLECTING DUCT
1132. The advantage of dry heat: DOESN’T CAUSE CORROSION OF METAL INSTRUMENTS
1133. The result of exon activity: CHANGES DNA SEQUENCE, REVERSE TRANSCRIPT, MISSENSE, NONSENSE
1134. Eagle’s syndrome: STYLOHYOID SYNDROME
Eagle syndrome (stylohyoid syndrome, styloid syndrome, styloid-stylohyoid syndrome or styloid–carotid artery syndrome) is a rare
condition commonly characterized but not limited to - sudden, sharp nerve-like pain in the jaw bone and joint, back of the throat, and
base of the tongue, triggered by swallowing, moving the jaw, or turning the neck. Since the brain to body's nerve connections pass
through the neck; many seemingly random symptoms can be triggered by impingement or entanglement. The condition is caused by
an elongated or misshapen styloid process, the slender, pointed piece of bone just below the ear, and/or calcification of the stylohyoid
ligament, which interferes with the functioning of neighboring regions in the body, giving rise to pain.
Possible symptoms include:
• Sharp, shooting pain in the jaw, back of the throat, base of the tongue, [1] ears, neck, and/or face
• Difficulty swallowing
• Sensation of having a foreign object in throat
• Pain from chewing, swallowing, turning the neck, or touching the back of the throat
• Ringing or buzzing in the ears
Classic eagle syndrome is present on only one side, however, rarely, it may be present on both sides.
In vascular Eagle syndrome, the elongated styloid process comes in contact with the internal carotid artery below the skull. In these
cases, turning the head can cause compression of the artery or a tear inside the blood vessel, which restricts BF and can potentially
lead to a transient ischemic attack (TIA) or stroke.
1135. Function of the masseter: SLING MUSCLE, ELEVATION OF THE MANDIBLE, STRONGEST MUSCLE OF MASTICATION
1136. Cranial nerves with parasympathetic function: III, VII, IX, X
1137. Clogged ears can be caused by a restricted function of: TENSOR VELI PALATINI OR SALPINGOPHARYNGEUS
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1138. Blood and nerve supply to the larynx
All muscles of the larynx are supplied by recurrent laryngeal nerve (except: cricothyroid by external branch of superior laryngeal nerve).
Blood supply is provided by superior & inferior laryngeal arteries.
1140. Function of aryepiglottic fold: PHONATION (located at the entrance of larynx), CLOSETS THE INLET, PREVENTS FOOD FROM
ENTERING THE AIRWAY
1141. Steroid hormones: ESTROGEN & PROGESTERONE (OVARIES), ADRENAL CORTEX HORMONES
1142. Transports FA: ALBUMIN
1143. IL-2: PRODUCED BY T CELLS, ATTRACT MORE T CELLS
1144. Protection against hepatitis B: VACCINE; WHEN CONCENTRATION OF IgG IN SERUM IS HIGH
1145. Viremia: VIRUS STARTS RULING IN THE BLOOD
1146. Dry heat sterilizes by: KILLING THE SPORES
1147. Edema may result from: HYPERTENSION
1148. Primary molars lack: MAMELONS
1149. Muscle protein caused increase blood glucose level the released alanine cause: LIVER TO PRODUCE GLUCOSE, MUSCLE ITSELF
TO PRODUCE GLUCOSE, TRANSFER PROTEIN TO THE LIVER THAT WILL FORM THE GLUCOSE
1150. Condensed chromatin: HETEROCHROMATIN
1151. Warfarin lab test: PT & INR
1152. Histamine is produced by: OXYNTIC GLANDS
1153. Similarity between MX 1st and 2nd premolar: TRAPEZOIDAL PROXIMAL SHAPE
1154. Pain from teeth on the right side: LEFT PARIETAL LOBE
The spinal trigeminal nucleus (nucleus of fascial pail) cross over the contralateral VPM and then to the parietal lobe. In case of normal
sensation, it’s the right lobe, because the main sensory nucleus will not cross over, so it’s ipsilateral.
1155. Ear is developed from which arch pouch: 1st PHARYNGEAL CLEFT
1156. Glossopharyngeal muscle: 3rd PHARYNGEAL ARCH
1157. All of the following are innervated by the glossopharyngeal nerve except: PALATOGLOSSUS
Palatoglossus is the only muscle of the tongue that is not innervated by the hypoglossal nerve (CN XII). It is innervated by the vagus
nerve (CNX).
By inhibiting the Na+/K+-ATPase, cardiac glycosides cause intracellular sodium concentration to increase. This then leads to an
accumulation of intracellular calcium via the Na+-Ca++ exchange system. In the heart, increased intracellular calcium causes more
calcium to be released by the sarcoplasmic reticulum, thereby making more calcium available to bind to troponin-C, which increases
contractility (inotropy). Inhibition of the Na +/K+-ATPase in vascular smooth muscle causes depolarization, which causes smooth muscle
contraction and vasoconstriction.
TMJ disc is cartilage so it doesn't appear in panoramic and looks like radiolucent so bony structure of TMJ will cover it.
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1180. Prostate cancer: PROSTATE SPECIFIC ANTIGEN AND IN ACID PHOSPHATASE
1181. Iron storage in the body: FERRITIN
1182. The only function of the spinal cord in CNS: SIMPLE REFLEXES, COORDINATION OF THE MOTOR MOVEMENT, RESPIRATION
1183. Organism with a polypeptide capsule: BACILLUS ANTHRACIS
1184. All of these fungi spread from person to person, except: CANDIDA
1185. N-glutamic acid found in: THE CELL WALL
1186. Tay-Sachs disease cause: CNS DEGENERATION, DEVELOPMENTAL RETARDATION, CHERRY SPOT ON THE MACULA, RAPIDLY
FATAL CONDITION
1187. Rough cocci get the DNA from soft cocci through: TRANSFORMATION
1188. Endothelial fungi: MUCORMYCOSIS
1189. Mycotic organism: MUCORMYCOSIS
1190. Longest and shortest root of the MX molar: PALATAL (LONGEST) & DB (SHORTEST)
1191. The location of the palatal canal; under what cusp: ML
1192. The mesial view of the incisal edge of MN central incisor: MMR = DDR; DI corner is as sharp as MI; INCISAL EDGE LINGUAL TO
LONG AXIS (FROM PROXIMAL)
1193. Failing RCT in lower canine due to: 6% WITH 2 COMPLETE ROOT CANALS, BIFURCATED ROOT, OCASIONALLY 2 ROOTS (LABIAL
& LINGUAL)
1194. Lower canine canal shape: ROUGHLY OVAL
1195. PSA to MX 2nd molar, what other nerve with the same injection could get anesthetized too:
1196. Root and incisal edge comparison between lower central and lateral: ROOT IS LONGER IN LATERAL, INCISAL EDGE IS TWISTED
IN LATERAL (IN CENTRAL IT IS PERPENDICULAR TO B-L BISECTOR), INCISAL EDGE IS LINGUAL TO LONG AXIS IN BOTH
1197. Root completion of MX canine: 14
1198. Hypothyroidism is associated with: HASHIMOTO’S DISEASE
1199. The receptors damaged by autoantibodies in Myasthenia Gravis are: NICOTINIC
The autoimmune attack occurs when autoantibodies form against the nicotinic acetylcholine postsynaptic receptors at the
neuromuscular junction of skeletal muscles.
1200. The proximal contact area between MX central and MX lateral: AT JUNCTION OF INCISAL & MIDDLE THIRDS
1201. Submandibular gland innervation: CHORDA TYMPANI
1202. Disaccharide intolerance, why the patient can’t digest lactose (what is the defect exactly or why the deficiency of lactase in
disaccharide intolerance)
Lactose intolerance occurs when the small intestine does not make enough of an enzyme called lactase. Your body needs lactase to
break down, or digest, lactose. L. Acidophilus is added to milk products to aid in digestion of them. Bacterial enzymes convert milk
sugars to digestible products.
1203. What increases the action potential: A GENERATOR POTENTIAL ACTS TO INCREASE THE ACTION POTENTIAL FREQUENCY IN
RESPONSE TO INCREASED STIMULUS ACTIVITY; EXTRACELLULAR Na +
1204. Carcinoma in situ: CANCEROUS CELLS DO NOT INVIDE BASEMENT MEMBRANE
Carcinoma in situ (CIS), also known as in situ neoplasm, is a group of abnormal cells. While they are a form of neoplasm there is
disagreement over whether CIS should be classified as cancer. This controversy also depends on the exact CIS in question (i.e. cervical,
skin, breast). Some authors do not classify them as cancer, however, recognizing that they can potentially become cancer. Others
classify certain types as a non-invasive form of cancer. The term "pre-cancer" has also been used.
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1205. Muscle that helps in stabilization in maximum intercuspitation: SUPERIOR HEAD OF LATERAL PTERYGOID (if disc stabilization),
MASSETER (if mandible stabilization)
1206. Pitting edema: HYPOALBUMINEMIA
1207. Rheumatoid arthritis, why does it cause infective endocarditis: RHEUMATIC FEVER CAN CAUSE INFECTIVE ENDOCARDITIS;
DAMAGE TO THE HEART VALVES RESULTS IN AN INCREASED RISK OF BACTERIAL ATTACHMENT
The urea cycle consists of 5 reactions: 2 mitochondrial and 3 cytosolic. The cycle converts two amino groups, one from NH 4+ and one
from Asp, and a carbon atom from HCO3-.
- oblique fibers: outer fibers, articular eminence to neck and mandible; help guide condyle during opening
- horizontal fibers: deep fibers, articular eminence to lateral pole and posterior disc; limits posterior movement of condyle
1226. Contour lines of Owen (in dentin) can be analogous to: STRIAE OF RETZIUS (FOUND IN ENAMEL)
1227. Not a part of the enamel: ENAMEL SPINDLE
1228. Sympathetic effect on an eye: PUPIL DILATATION
83
1229. Hard palate behind the central incisors formed by: PREMAXILLA, BY MEDIAL NASAL PROCESS
1230. An organ below/near the right kidney: COLON, LIVER, DUODENUM
1231. Epidural hematoma: MIDDLE MENINGEAL ARTERY
1232. Gout characteristic: NIGHT PAIN, SKIN ERYTHEMA, KIDNEY STONES
1233. Sudden cardiac arrest: CARDIAC TAMPONADE
1234. MOA of methotrexate: INHIBITS THE SYNTHESIS OF FOLIC ACID, WHICH IS IMPORTANT FOR THE SYNTHESIS OF PURINES AND
THYMINE
1235. Aschoff bodies: RHEUMATIC FEVER
1236. Not a part of an oral epithelium: STRATUM LUCIDUM (skin of the palms, soles)
1237. All true about AIDS, except: IT IS AN OPPORTUNISTIC DISEASE
1238. Alzheimer’s characteristic: AMYLOID DEPOSITS
1239. Herpangina: THROAT, SOFT PALATE, TONGUE, ORAL LESIONS
Viral disease with oral manifestations; 3 year-olds with fever, vesicles, ulcers on soft palate & larynx.
Suboccipital triangle- deep in the triangle passes the vertebral artery and the suboccipital nerve (aka dorsal ramus of C1).
1243. The immune system fights Staph. aureus, what doesn’t contribute: GAMMA INTERFERON
1244. Last product of urea: ORNITHINE & UREA
1245. Which vitamins are important for enamel and bone: VITAMIN C, VITAMIN D
1246. Patient with an injury from T4, what will you be afraid of during dental treatment: BLADDER EMPTYING
An injury above T12/L1 often prevents central control of the bladder function. Reflex impulses take over, causing the sphincter muscle
holding urine in the bladder and the bladder itself work against each other. If bladder pressure gets too high, it can cause incontinence
(leakage), or a dangerous back-up of urine into the kidneys. Treatment is usually to reduce bladder pressure with medicine and empty
the bladder with clean intermittent catheterization (CIC).
1247. If the pH becomes lower than the isoelectric point of a protein, then how will the protein respond in an electrophoretic system:
IT WILL MIGRATE TO THE NEGATIVE POLE
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1248. A patient has xerostomia, she licks lollipops to moist her mouth, what would the dentist recommend for her instead of this
habit: CHEWING GUM
1249. A 50-year-old man comes for an orthodontic treatmet. He has an FPD on #12-#14. Need to remove the anterior abutment. What
is the following is not likely to be a complication in the extraction of this tooth: ONE ROOT
1250. ATP is attached to which component of skeletal muscle: MYOSIN HEAD
1251. Nerve that don’t pass through jugular formen: CN XII (CN IX, X, XI pass)
1252. Achalasia is related to: ESOPHAGUS
1253. Submucosa found in: STOMACH, SMALL & LARGE INTESTINE
1254. Caries is most likely to develop on which anterior tooth: LATERAL MAXILARY INCISOR
1255. Blastomycosis: IN SOIL
1256. Rathke’s pouch gives rise to: ADENOHYPOPHYSIS
1257. MN premolar erupts: 10-12 YEARS, BEFORE THE COMPLETION OF THE ROOT FORMATION
1258. LMN is located: VENTRAL HORN OF THE SPINAL CORD
1259. What is the vagus nerve responsible for: CEPHALIC PHASE OF GASTRIC SECRETION
1260. Squamous epithelial metaplasia seen in: BRONCHIAL MUCOSA
1261. Keratohyalin granules seen in: STRATUM GRANULOSUM
1262. Preganglionic autonomic nerve fibers, where are they located: WHITE RAMUS COMMUNICANS
1263. When secondary cementum is built, everything is expected to occur except: BLOOD VESSELS
1264. Allosteric activation of glycolysis: cAMP, Pi, FRUCTOSE-2,6-BISPHOSPHATASE
1265. Tooth #17 has to be extracted, each of the following justifies the extraction, except: IT WOULD CAUSE THE RESORPTION OF
THE DISTAL ROOT OF MN RIGHT 2nd MOLAR
1266. What will not elevate the larynx: INFRAHYOID MUSCLES
1267. IAN didn’t work, what is the cause: INJECTED INTO THE PAROTID GLAND
1268. Hyperthyroidism, rheumatoid arthritis – what is the cause: AUTOIMMUNE
1269. NE production: POSTSYNAPTIC SYMPATHETIC FIBERS
1270. Mamelons in a 17-yeard-old are a result of: MALOCCLUSION, ANTERIOR OPEN BITE
1271. Most anterior-superior position: CR
1272. TSH decreased, why: ANTIBODIES AGAINST THE TSH RESEPTORS OF THE THYROID CELLS
1273. Angina pectoris: NITROGLYCERATE
1274. What would you expect in a patient with Graves’ disease: EXOPHTHALMUS
1275. All of these hormones are present in pre-pregnancy state except: BETA hCG
1276. All of these are used to identify a dead body except: MITOCHONDRIAL mRNA
1277. What damage comes from the bite: NECROSIS
1278. TMJ load bearing: TRUE
1279. What is not from the 1st arch: BUCCINATOR MUSCLE
1280. Lewy bodies: PARKINSON DISEASE
1281. Not in dermis: MERKEL, MELANIN
1282. Multiple drug resistance: PLASMIDS
85
• Blue bloaters – chronic bronchitis
• Russell bodies and Mott cells – multiple myeloma
• Lipschultz body – HSV
• Civatte bodies – lichen planus
• Osteogenesis imperfecta – blue sclera + brittle bones
• Lewy bodies – Parkinson disease
• Negri bodies – rabies
• Albert’s bone disease – marble bones
• Spleen enlargement – myelofibrosis
• Behcet’s Disease – mouth sores (chronic), skin blisters
• Hemophilia A – deficiency of factor VIII
• Osteomalacia – deficiency of vitamin D
• Ecchymosis – purpura (large) / petechiae (small)
• Paget’s disease of bones – serum alkaline phosphate
• Acute gouty arthritis – uric acids deposits
• Sever hemolytic disease – fetus has Rh+ and mother Rh-
• Erythema multiform – target, iris, bull’s eye shape
• Neimann-Pick disease - genetic defect in the enzyme sphingomyelinase
• Tay-Sachs disease – deficiency of the enzyme hexosaminidase
• Neurologic dysfunction – vitamin E deficiency
• Addison’s disease – increased melanin pigmentation
• Albinism and vitiligo – decreased melanin pigmentation
• Vitamin B1 deficiency – beri-beri
• Hashimoto disease – hypothyroidism by a reaction of immune system against the thyroid gland
• Diabetes insipidus – extreme thirst and excessive urine output
• Acute pancreatitis – elevation of both enzymes: lipase (more) and amylase
• Pellagra – vitamin B3 deficiency
• Osteoporosis – drop in estrogen (women) at time of menopause / drop in testosterone in men
• Sickle cell anemia – abnormal type of Hb
• Osteoarthritis – osteophyte formation
• Exophthalmos – Grave’s disease
• Cri-du-chat syndrome – cat-like cry: chromosome 5
• Edwards’ syndrome – micrognathia, pinched face: trisomy 18.
• Patau syndrome – cleft lip and palate: trisomy 13
• DiGeorge syndrome – deletion in chromosome 22: CATCH 22
• Tetanus – risus sardonicus, opisthotonus
• Tetany – Trousseau’s sign and Chvostek's sign
• Klinefelter syndrome – XXY
• Turner’s syndrome – XO
• Primary hyperparathyroidism – adenoma
• Pseudoparathyroidism – defective end-organ responsiveness to PTH
• Nuclear pyknosis – irreversible cellular injury
• Shock, progressive stage – metabolic acidosis
• SCID – absence of B and T cells
• Acromegaly – increased GH in adults
• Gigantism – increased GH in childhood before epiphysial closure
• Hypovolemic shock – blood loss
• Hydronephrosis – chronic urinary tract obstruction
• Lung abscess – MC cause is aspiration of anaerobic bacteria
• Emphysema – cigarettes smoking
• Hepatitis B – DNA virus, enveloped
• Lung cancer – persistent cough
• Pheochromocytoma – cardinal sign is persistent or paroxysmal hypertension
• Primary tubercle – Ghon tubercle
• Primary syphilis – non-painful chancre
• Secondary syphilis – maculopapular rash and condylomata lata
• Tretiary syphilis – gumma
• Myxedema – extreme hypothyroidism
86
HOW TO REMEMBER THESE BAD BOYS
MERKEL PRESSURE/TEXTURE
Angela Merkel from Germany wears textured outfits and works under a lot of pressure.
PACINIAN VIBRATION
Pacman, the game for your phone – when you die, the phone vibrates.
87