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Contraindications Hypersensitivity; Some products contain alcohol and should be avoided in patients with known intolerance; Some
products contain aspartame and should be avoided in patients with phenylketonuria.
Nursing Care/Monitoring Access for abdominal pain, blood in stool, emesis, or gastric aspirate. Access for confusion in geriatric
patients. Monitor CBC with differential. May cause false-positive results for urine protein.
Common Side Effects confusion, dizziness, drowsiness, hallucinations, headache. constipation, diarrhea, drug-induced hepatitis,
nausea. Decreased sperm count, gynecomastia, anemia, neutropenia, thrombocytopenia. pain at IM site. hypersensivity reactions,
vasculitis.
Life Threatening Side Effects arrhythmias, agranulocytosis, aplastic anemia
Peak: 1-4 hours Onset: within 60 minutes Duration: 6-12 hours
Evaluation: Did this medication work for the intended purpose? How? Why? Yes, my patient did not display symptoms of gastric
ulcers or GERD.
Life Threatening Side Effects Stevens-Johnson syndrome, toxic epidermal necrolysis, or erythema multiforme. Aplastic anemia,
agranulocytosis
Common Side Effects confusion, dizziness, headache, insomnia, lethargy, diarrhea, constipation, drug-induced hepatitis, nausea,
vomiting. interstitial nephritis. rashes (increased risk in cystic fibrosis patients), urticaria. Bleeding, leukopenia, neutropenia,
thrombocytopenia. Local: pain, phlebitis at IV site. Hypersensitivity reactions, fever (increased risk in cystic fibrosis patients),
superinfection
Life Threatening Side Effects Seizures in high doses, pseudomembranous colitis, Stevens-Johnson Syndrome, Toxic Epidermal
Necrolysis, Anaphylaxis and Serum sickness
Peak: end of infusion Onset: rapid Duration: 4-6 hours
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question)
Generic Name Epoetin Alfa
Brand Name Epogen
Classification Antianemics
Dosage: 10,000 units subcutaneous qTThSa Injection for hemoglobin less than 11 g/dL
Action: Stimulates erythropoiesis (production of red blood cells).
Why is patient taking? Anemia associated to CKD
How does the medication work, the therapeutic effects? Put in terms your patient would understand. This injection maintains and may
elevate RBCs, decreasing the need for blood transfusions.
Contraindications Hypersensitivity to albumin or mammalian cell-derived products; Uncontrolled hypertension; Patients with
erythropoietin levels greater than 200 mUnits/mL; Patients receiving chemotherapy when anticipated outcome is cure; Neutropenia in
newborns.
Nursing Care/Monitoring
● Monitor hematocrit before and twice weekly during initial therapy, for 2 – 6 wk after a change in dose, and regularly after target
range (30 – 36%) has been reached and maintenance dose is determined. Monitor other hematopoietic parameters
● Monitor renal function studies and electrolytes closely; resulting increased sense of well-being may lead to decreased compliance
with other therapies for renal failure. Increases in BUN, creatinine, uric acid, phosphorus, and potassium may occur.
● Monitor BP before and during therapy. Inform health care professional if severe hypertension is present or if BP begins to increase.
Additional anti- hypertensive therapy may be required during initiation of therapy.
● Monitor for symptoms of anemia (fatigue, dyspnea, pallor).
● Monitor dialysis shunts (thrill and bruit) and status of artificial kidney during hemodialysis. Heparin dose may need to be increased
to prevent clotting. Monitor patients with underlying vascular disease for impaired circulation.
Common Side Effects headache. Hypertension. transient rashes. restored fertility, resumption of menses. Increased mortality and
increased tumor growth (with hemoglobin greater than 12 g/dL).
Life Threatening Side Effects seizures, stroke, HF, MI, thromboembolic events with hemoglobin greater than 11 g/dL
Peak: within 2 months Onset: 7-10 days Duration: 2 weeks
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question)
Generic Name Atorvastatin
Brand Name Lipitor
Classification Statin
Dosage: 20 mg PO qDay
Action: maintains and lowers lipid levels
Why is patient taking? Prevention of heart disease, reduce risk of stroke
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Lowers levels of bad cholesterol
and increases levels of good cholesterol.
Contraindications Liver disease, Renal impairment, concurrent use of antifungals
Nursing Care/Monitoring avoid grapefruit, provide education pertaining to diet and exercise, reduce risk of plaque build up, provide
smoking cessation, explain importance of follow up exam
Common Side Effects amnesia, confusion, dizziness, headache
Life Threatening Side Effects Rhabdomyolysis, hypersensitivity rxn, angioneurotic edema
Peak: 1-2 hours Onset: Initial changes: 3 to 5 days; Maximal reduction in plasma cholesterol and triglycerides: 2 to 4 weeks;
LDL reduction: 10 mg/day: 39% (for each doubling of this dose, LDL is lowered approximately 6%) Duration: 20-30 hours
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question)
Why is patient taking? Diminished accumulation of acid in the gastric lumen, with lessened acid reflux. Healing of duodenal ulcers
and esophagitis. Decreased acid secretion in hypersecretory conditions.
How does the medication work, the therapeutic effects? Prevention of GI ulcers.
Contraindications Hypersensitivity; OB: Should be used during pregnancy only if clearly needed; Lactation: Discontinue breast
feeding due to potential for serious adverse reactions in infants.
Nursing Care/Monitoring
● Assess patient routinely for epigastric or abdominal pain and for frank or occult blood in stool, emesis, or gastric aspirate.
● May cause abnormal liver function tests, including increased AST, ALT, alkaline phosphatase, and bilirubin.
● May cause hypomagnesemia. Monitor serum magnesium prior to and periodically during therapy.
Common Side Effects CNS: headache. GI: PSEUDOMEMBRANOUS COLITIS, abdominal pain, diarrhea, eructation, flatulence.
Endo: hyperglycemia. F and E: hypomagnesemia (especially if treatment duration 3 mo). MS: bone fracture.
Life Threatening Side Effects Psuedomembranous Colitis
Peak: Unknown Onset: 2.5 hr Duration: 1 week
Evaluation: Did this medication work for the intended purpose? How? Why?
Action: Lowers B/P by β-blocking effects; reduces elevated renin plasma levels; blocks β2-
adrenergic receptors in bronchial, vascular smooth muscle only at high doses, negative
chronotropic effect
Contraindications: Hypersensitivity to β-blockers, cardiogenic shock, heart block (2nd and 3rd
degree), sinus bradycardia, pheochromocytoma, sick sinus syndrome
Common Side Effects: Colitis, cramps, diarrhea, constipation, flatulence, dry mouth, hiccups,
dizziness, hallucinations, anxiety, headaches, confusion, insomnia, sore throat, dry burning
eyes, impotence, and rash
Evaluation: Did this medication work for the intended purpose? How? Why? (this is not just a
yes/no question)
Generic Name Losartan
Brand Name Cozaar
Classification Angiotensin II Receptor Antagonists
Dosage: 100 mg PO aDay
Action: Blocks vasoconstrictor and aldosterone-producing effects of angiotensin II at receptor sites, including vas- cular smooth
muscle and the adrenal glands.
Why is patient taking? Decreased risk of stroke in patients with hypertension and left ventricular hypertrophy
How does the medication work, the therapeutic effects? Put in terms your patient would understand. This medication helps to lower
blood pressure and reduces risk of stroke in HTN.
Contraindications Hypersensitivity; Concurrent use with aliskiren in patients with diabetes or moderate-to-severe renal impairment
Nursing Care/Monitoring
● Assess BP and pulse periodically during therapy. Notify health care professional of significant changes.
● Monitor frequency of prescription refills to determine adherence.
● Assess patient for signs of angioedema (dyspnea, facial swelling). May rarely cause angioedema.
● HF: Monitor daily weight and assess patient routinely for resolution of fluid overload (peripheral edema, rales/crackles, dyspnea,
weight gain, jugular venous distention).
Common Side Effects CNS: dizziness, anxiety, depression, fatigue, head- ache, insomnia, weakness. CV: hypotension, chest pain,
edema, tachycardia. Derm: rashes. EENT: nasal congestion, pharyngitis, rhinitis, sinusitis. GI: abdominal pain, diarrhea, drug-induced
hepatitis, dyspepsia, nausea, vomiting. GU: impaired renal function. F and E: hyperkalemia. MS: arthralgia, back pain, myalgia.
Life Threatening Side Effects angioedema
Peak: 3-6 weeks Onset: 6 hours Duration: 24 hours
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question)
● Antacid: Assess for heartburn and indigestion as well as location, duration, character, and precipitating factors of gastric pain.
● Monitor serum phosphate, potassium, and calcium levels periodically during chronic use. May cause increase serum calcium and
decrease serum phosphate concentrations.
Dosage: 81 mg qDay
How does the medication work, the therapeutic effects? Put in terms your patient would
understand. This medication is used a precautionary drug to help with decreasing the risk of
having a stroke
Nursing Care/Monitoring: Assess for pain before and 1 hours after administration; assess for
edema in feet, ankles, legs; Assess for ototoxicity; allergic reactions and monitor liver/renal
and blood studies.
Common Side Effects: rash, urticaria, bruising, diarrhea, pulmonary edema, dizziness,
confusion, rapid pulse, tinnitus, hypo-glycemia/natremia/kalemia.
Life Threatening Side Effects: Hepatotoxicity: dark urine, clay-colored stools, yellowing of the
skin and sclera, itching, abdominal pain, fever, diarrhea if patients are on long term.
Evaluation: Did this medication work for the intended purpose? How? Why? (this is not just a
yes/no question) Yes, there were no signs of reoccurring ischemic attacks.
Action: Lowers B/P by β-blocking effects; reduces elevated renin plasma levels; blocks β2-
adrenergic receptors in bronchial, vascular smooth muscle only at high doses, negative
chronotropic effect
Contraindications: Hypersensitivity to β-blockers, cardiogenic shock, heart block (2nd and 3rd
degree), sinus bradycardia, pheochromocytoma, sick sinus syndrome
Common Side Effects: Colitis, cramps, diarrhea, constipation, flatulence, dry mouth, hiccups,
dizziness, hallucinations, anxiety, headaches, confusion, insomnia, sore throat, dry burning
eyes, impotence, and rash
Evaluation: Did this medication work for the intended purpose? How? Why? (this is not just a
yes/no question) The patient was not given this medication because his systolic blood pressure
was <100 mmHg.
Generic Name Insulin Aspart
Brand Name NovoLOG
Classification Antidiabetics, hormone
Dosage: sliding scale subcutaneous injection qidACbedtime
Action: Lower blood glucose by: stimulating glucose uptake in skeletal muscle and fat, inhibiting hepatic glucose production. Other
actions: inhibition of lypolysis and proteolysis, enhanced protein synthesis. These are rapid-acting insulins with a more rapid onset
and shorter duration than regular insulin; should be used with an intermediate or long-acting insulin.
Why is patient taking? Control of hyperglycemia in patients with type 1 or type 2 diabetes mellitus.
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Control of high blood sugar due
to diabetes
Contraindications Hypoglycemia; Allergy or hypersensitivity to a particular type of insulin, preservatives, or other additives.
Nursing Care/Monitoring Assess for symptoms of hypoglycemia (anxiety; restlessness; tingling in hands, feet, lips, or tongue; chills;
cold sweats; confusion; cool, pale skin; difficulty in concentration; drowsiness; nightmares or trouble sleeping; excessive hunger;
headache; irritability; nausea; nervousness; tachycardia; tremor; weakness; unsteady gait) and hyperglycemia (confusion, drowsiness;
flushed, dry skin; fruit-like breath odor; rapid, deep breathing, polyuria; loss of appetite; nausea; vomiting; unusual thirst) periodically
during therapy.
● Monitor body weight periodically. Changes in weight may necessitate changes in insulin dose.
● Assess patient for signs of allergic reactions (rash, shortness of breath, wheezing, rapid pulse, sweating, low BP) during therapy.
● Lab Test Considerations: May cause decreased serum inorganic phosphate, magnesium, and potassium levels.
● Monitor blood glucose every 6 hr during therapy, more frequently in ketoacidosis and times of stress. A1C may also be monitored
every 3 – 6 mo to determine effectiveness.
● Toxicity and Overdose: Overdose is manifested by symptoms of hypoglycemia. Mild hypoglycemia may be treated by ingestion of
oral glucose. Severe hypoglycemia is a life-threatening emergency; treatment consists of IV glucose, glucagon, or epinephrine. Early
signs of hypoglycemia may be less pronounced by long duration of diabetes, diabetic nerve disease, and use of beta blockers; may
result in loss of consciousness prior to patient’s awareness of hypoglycemia.
Common Side Effects hypoglycemia, erythema, lipodystrophy, pruritus, swelling.
Life Threatening Side Effects HYPOGLYCEMIA and ANAPHYLAXIS.
Peak: 1-2 hours Onset: within 15 minutes Duration: 3-4 hours
Evaluation: Did this medication work for the intended purpose? How? Why? This medication was not given during his hospitalization
because blood glucose was controlled.
Why is patient taking? Diminished accumulation of acid in the gastric lumen, with lessened acid reflux. Healing of duodenal ulcers
and esophagitis. Decreased acid secretion in hypersecretory conditions.
How does the medication work, the therapeutic effects? Prevention of GI ulcers.
Contraindications Hypersensitivity; OB: Should be used during pregnancy only if clearly needed; Lactation: Discontinue breast
feeding due to potential for serious adverse reactions in infants.
Nursing Care/Monitoring
● Assess patient routinely for epigastric or abdominal pain and for frank or occult blood in stool, emesis, or gastric aspirate.
● May cause abnormal liver function tests, including increased AST, ALT, alkaline phosphatase, and bilirubin.
● May cause hypomagnesemia. Monitor serum magnesium prior to and periodically during therapy.
Common Side Effects CNS: headache. GI: PSEUDOMEMBRANOUS COLITIS, abdominal pain, diarrhea, eructation, flatulence.
Endo: hyperglycemia. F and E: hypomagnesemia (especially if treatment duration 3 mo). MS: bone fracture.
Life Threatening Side Effects Psuedomembranous Colitis
Peak: Unknown Onset: 2.5 hr Duration: 1 week
Evaluation: Did this medication work for the intended purpose? How? Why? Yes, patient did not have any acid reflux symptoms and
did not display evidence of gastric ulcer.
Generic Name Potassium Chloride
Brand Name Klor-Con
Classification mineral and electrolyte replacements/supplements
Dosage: 20-60 mEq PO as directed for hypokalemia
Action: Maintain acid-base balance, isotonicity, and electrophysiologic balance of the cell. Activator in many enzymatic reactions;
essential to transmission of nerve impulses; contraction of cardiac, skeletal, and smooth muscle; gastric secretion; renal function;
tissue synthesis; and carbohydrate metabolism.
Why is patient taking? hypokalemia
How does the medication work, the therapeutic effects? To restore levels of potassium
Contraindications Hyperkalemia; Severe renal impairment; Untreated Addison’s disease; Severe tissue trauma; Hyperkalemic familial
periodic paralysis; Some products may contain tartrazine (FDC yellow dye #5) or alcohol; avoid using in patients with known
hypersensitivity or intolerance; Potassium acetate injection contains aluminum, which may become toxic with prolonged use to high
risk groups (renal impairment, premature neonates).
Nursing Care/Monitoring
● Assess for signs and symptoms of hypokalemia (weakness, fatigue, U wave on ECG, arrhythmias, polyuria, polydipsia) and
hyperkalemia
● Monitor pulse, BP, and ECG periodically during IV therapy.
● Monitor serum potassium before and periodically during therapy. Monitor renal function, serum bicarbonate, and pH. Determine
serum magnesium level if patient has refractory hypokalemia; hypomagnesemia should be corrected to facilitate effectiveness of
potassium replacement. Monitor serum chloride because hypochloremia may occur if replacing potassium without concurrent
chloride.
● Toxicity and Overdose: Symptoms of toxicity are those of hyperkalemia (slow, irregular heart- beat; fatigue; muscle weakness;
paresthesia; confusion; dyspnea; peaked T waves; depressed ST segments; prolonged QT segments; widened QRS complexes; loss of
P waves; and cardiac arrhythmias).
● Treatment includes discontinuation of potassium, administration of sodium bicarbonate to correct acidosis, dextrose and insulin to
facilitate passage of potassium into cells, calcium salts to reverse ECG effects (in patients who are not receiving digoxin), sodium
polystyrene used as an exchange resin, and/ or dialysis for patient with impaired renal function.
Common Side Effects CNS: confusion, restlessness, weakness. CV: ARRHYTHMIAS, ECG changes. GI: abdominal pain, diarrhea,
flatulence, nausea, vomiting; tablets, capsules only, GI ulceration, stenotic lesions. Local: irritation at IV site. Neuro: paralysis,
paresthesia.
Life Threatening Side Effects arrhythmias and ECG changes
Peak: 1-2 hours Onset: UNKNOWN Duration: UNKNOWN
Evaluation: Did this medication work for the intended purpose? How? Why? The patient was not given this medication because his
potassium was within normal ranges.
● Antacid: Assess for heartburn and indigestion as well as location, duration, character, and precipitating factors of gastric pain.
● Monitor serum phosphate, potassium, and calcium levels periodically during chronic use. May cause increase serum calcium and
decrease serum phosphate concentrations.
Nursing Care/Monitoring: Monitor BP, INO, daily weight, assess edema, dyspnea, JVD
Evaluation: Did this medication work for the intended purpose? How? Why? (this is not just a yes/no question) Yes, the patient’s blood pressure
was within normal ranges during her hospitalization.
Nursing Care/Monitoring: Monitor BP, INO, daily weight, assess edema, dyspnea, JVD
Evaluation: Did this medication work for the intended purpose? How? Why? (this is not just a yes/no question) Yes, the patient displayed no
asthma symptoms.
● Antacid: Assess for heartburn and indigestion as well as location, duration, character, and precipitating factors of gastric pain.
● Monitor serum phosphate, potassium, and calcium levels periodically during chronic use. May cause increase serum calcium and
decrease serum phosphate concentrations.
Dosage: 81 mg qDay
Action: Blocks pain impulses in CNS, reduces inflammation by inhibition of prostaglandin synthesis; antipyretic action results from vasodilatation of
peripheral vessels; decreases platelet aggregation
How does the medication work, the therapeutic effects? Put in terms your patient would understand. This medication is used a precautionary drug to
help with decreasing the risk of having a stroke
Contraindications: GI bleeding, bleeding disorders, vit K deficiency, peptic ulcer, acute bronchospasm, agranulocytosis, increased intracranial
pressure, intracranial bleeding, nasal polyps, urticaria
Nursing Care/Monitoring: Assess for pain before and 1 hours after administration; assess for edema in feet, ankles, legs; Assess for ototoxicity;
allergic reactions and monitor liver/renal and blood studies.
Common Side Effects: rash, urticaria, bruising, diarrhea, pulmonary edema, dizziness, confusion, rapid pulse, tinnitus, hypo-
glycemia/natremia/kalemia.
Life Threatening Side Effects: Hepatotoxicity: dark urine, clay-colored stools, yellowing of the skin and sclera, itching, abdominal pain, fever,
diarrhea if patients are on long term.
Nursing Care/Monitoring
Assess type, location, and intensity of pain before and 2 – 3 hr (peak) after administration.
Assess BP and respiratory rate before and periodically during administration. Respiratory depression has not occurred with
recommended doses.
Assess bowel function routinely. Prevention of constipation should be instituted with increased intake of fluids and bulk and with
laxatives to minimize constipating effects.
Assess previous analgesic history. Tramadol is not recommended for patients dependent on opioids or who have previously
received opioids for more than 1 week; may cause opioid withdrawal symptoms.
Prolonged use may lead to physical and psychological dependence and tolerance, although these may be milder than with opioids.
This should not pre- vent patient from receiving adequate analgesia. Most patients who receive tramadol for pain do not
develop psychological dependence. If tolerance develops, changing to an opioid agonist may be required to relieve pain.
Overdose may cause respiratory depression and seizures. Naloxone may reverse some, but not all, of the symptoms of over- dose.
Treatment should be symptomatic and sup- portive. Maintain adequate respiratory exchange. Hemodialysis is not helpful because it
removes only a small portion of administered dose. Seizures may be managed with barbiturates or benzodiazepines; naloxone
increases risk of seizures.
Common Side Effects CNS: SEIZURES, dizziness, headache, somnolence, anxiety, CNS stimulation, confusion, coordination distur-
bance, euphoria, malaise, nervousness, sleep disorder, weakness. EENT: visual disturbances. CV: vasodilation. GI: constipation,
nausea, abdominal pain, anorexia, diarrhea, dry mouth, dyspepsia, flatulence, vomiting. GU: menopausal symptoms, urinary
retention/frequency. Derm: pruritus, sweating. Neuro: hypertonia. Misc: SEROTONIN SYNDROME, physical dependence,
psychological dependence, tolerance.
Life Threatening Side Effects Seizures and Serotonin Syndrome
Peak: 2-3 hours Onset: 1 hour Duration: 4-6 hours
Evaluation: Did this medication work for the intended purpose? How? Why? Yes, the patient’s pain was reduced upon administration
of the drug.
● Antacid: Assess for heartburn and indigestion as well as location, duration, character, and precipitating factors of gastric pain.
● Monitor serum phosphate, potassium, and calcium levels periodically during chronic use. May cause increase serum calcium and
decrease serum phosphate concentrations.
Classification: Statin
Dosage: 80 mg qDay
How does the medication work, the therapeutic effects? Put in terms your patient would
understand. Lowers levels of bad cholesterol and increases levels of good cholesterol.
Nursing Care/Monitoring: avoid grapefruit, provide education pertaining to diet and exercise,
reduce risk of plaque build up, provide smoking cessation, explain importance of follow up
exam
Evaluation: .
How does the medication work, the therapeutic effects? Put in terms your patient would understand. This medication helps to lower
blood pressure and reduces risk of stroke in HTN.
Contraindications Hypersensitivity; Concurrent use with aliskiren in patients with diabetes or moderate-to-severe renal impairment
Nursing Care/Monitoring
● Assess BP and pulse periodically during therapy. Notify health care professional of significant changes.
● Monitor frequency of prescription refills to determine adherence.
● Assess patient for signs of angioedema (dyspnea, facial swelling). May rarely cause angioedema.
● HF: Monitor daily weight and assess patient routinely for resolution of fluid overload (peripheral edema, rales/crackles, dyspnea,
weight gain, jugular venous distention).
Common Side Effects CNS: dizziness, anxiety, depression, fatigue, head- ache, insomnia, weakness. CV: hypotension, chest pain,
edema, tachycardia. Derm: rashes. EENT: nasal congestion, pharyngitis, rhinitis, sinusitis. GI: abdominal pain, diarrhea, drug-induced
hepatitis, dyspepsia, nausea, vomiting. GU: impaired renal function. F and E: hyperkalemia. MS: arthralgia, back pain, myalgia.
Life Threatening Side Effects angioedema
Peak: 3-6 weeks Onset: 6 hours Duration: 24 hours
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question)
Dosage: 40 mg PO qDay
Action: Binds to an enzyme in the presence of acidic gastric pH, preventing the final transport of hydrogen ions into the gastric lumen
Why is patient taking? Diminished accumulation of acid in the gastric lumen, with lessened acid reflux. Healing of duodenal ulcers
and esophagitis. Decreased acid secretion in hypersecretory conditions.
How does the medication work, the therapeutic effects? Prevention of GI ulcers.
Contraindications Hypersensitivity; OB: Should be used during pregnancy only if clearly needed; Lactation: Discontinue breast
feeding due to potential for serious adverse reactions in infants.
Nursing Care/Monitoring
● Assess patient routinely for epigastric or abdominal pain and for frank or occult blood in stool, emesis, or gastric aspirate.
● May cause abnormal liver function tests, including increased AST, ALT, alkaline phosphatase, and bilirubin.
● May cause hypomagnesemia. Monitor serum magnesium prior to and periodically during therapy.
Common Side Effects CNS: headache. GI: PSEUDOMEMBRANOUS COLITIS, abdominal pain, diarrhea, eructation, flatulence.
Endo: hyperglycemia. F and E: hypomagnesemia (especially if treatment duration 3 mo). MS: bone fracture.
Evaluation: Did this medication work for the intended purpose? How? Why?
Dosage: 20 mg PO qDay
Action: Selectively inhibits the reuptake of serotonin in the CNS.
Why is patient taking? Depression. Unlabeled Use: Premenstrual dysphoric disorder (PMDD). Obsessive-compulsive disorder (OCD).
Panic disorder. Generalized anxiety disorder (GAD). Posttraumatic stress disorder (PTSD). Social anxiety disorder (social phobia).
How does the medication work, the therapeutic effects? Put in terms your patient would understand. This medication controls feelings
of depression.
Contraindications
Nursing Care/Monitoring
Common Side Effects ness, fatigue, impaired concentration, increases depression, migraine headache. EENT: abnormal
accommodation. Resp: cough. CV: postural hypotension, QT interval prolongation, tachycardia. GI: abdominal pain, anorexia,
diarrhea, dry mouth, dyspepsia, flatulence, increases saliva, nausea, altered taste, increases appetite, vomiting. GU: amenorrhea,
dysmenorrhea, ejaculatory delay, erectile dysfunction, polyuria. Derm: sweating, photosensitivity, pruritus, rash. Metab: weight loss,
weight gain. F and E: hyponatremia. MS: arthralgia, myalgia. Neuro: tremor, paresthesia. Misc: fever, yawning.
Life Threatening Side Effects NEUROLEPTIC MALIGNANT SYNDROME, SUICIDAL THOUGHTS, SEROTONIN
SYNDROME, TORSADE DE POINTES
Peak: UNKNOWN Onset: 1-4 wk Duration: UNKNOWN
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question)
How does the medication work, the therapeutic effects? Put in terms your patient would understand. This medication prevents/treats
iron deficiency.
Contraindications Hemochromatosis, hemosiderosis, or other evidence of iron overload; Anemias not due to iron deficiency; Some
products contain alcohol, tartrazine, or sulfites and should be avoided in patients with known intolerance or hypersensitivity.
Nursing Care/Monitoring
● Assess nutritional status and dietary history to determine possible cause of anemia and need for patient teaching.
● Assess bowel function for constipation or diarrhea. Notify health care professional and use appropriate nursing measures should
these occur.
Common Side Effects CNS: dizziness, headache, syncope. CV: IM, IV — hypotension, hypertension, tachycardia. GI: nausea; PO,
constipation, dark stools, diarrhea, epigastric pain, GI bleeding; IM, IV, taste disorder, vomiting. Derm: IM, IV — flushing, urticaria.
Resp: IV — cough, dyspnea. Local: pain at IM site (iron dextran), phlebitis at IV site, skin staining at IM site (iron dextran). MS: IM,
IV—arthralgia, myalgia. Misc: PO — staining of teeth (liquid preparations); IM, IV, allergic reactions including ANAPHYLAXIS,
fever, lymphadenopathy, sweating.
Life Threatening Side Effects Seizures, anaphylaxis
Peak: 7-10 days Onset: 4 days Duration: 2-4 mo
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question)
Pharmacological and Parenteral Therapy (Complete for all scheduled and PRN medications)
Generic Name: Cefazolin
Brand Name: Ancef
Classification: First generation cephalosporin
Dosage: 500 - 2000 mg q6-8hr IVP (max= 12g/day)
Action: Binds to bacterial cell wall membrane, causing cell death.
Why is patient taking the medication? Cellulitis infection in the lower extremities
IV push medication (rate of administration and dilution): Dilute with sterile water. Concentration: ≤ or equal to 100 mg/mL.
Administer slowly over 3-5 minutes.
How does the medication work, the therapeutic effects? Eliminates bacteria responsible for infection.
Contraindications: Hypersensitivity to cephalosporins or penicillins.
Nursing Care/Monitoring: Assess signs of infection. Obtain cultures. Observe for signs of anaphylaxis and keep epinephrine,
antihistamine, and resuscitative equipment nearby. Monitor for GI problems and fever to assess for CDAD. D/C if rash develops.
Common Side Effects: diarrhea, nausea, vomiting, cramps, rash, pruritis, urticaria, leukopenia, neutropenia, thrombocytopenia, pain
at IM site, phlebitis at IV site, serum sickness, superinfection
Life Threatening Side Effects: Seizures, CDAD, Stevens-Johnson syndrome, anaphylaxis
Pharmacological and Parenteral Therapy (Complete for all scheduled and PRN medications)
● Antacid: Assess for heartburn and indigestion as well as location, duration, character, and precipitating factors of gastric pain.
● Monitor serum phosphate, potassium, and calcium levels periodically during chronic use. May cause increase serum calcium and
decrease serum phosphate concentrations.
Action: Blocks stimulation of the beta1-adrenergic myocardial receptors to decrease BP and HR.
How does the medication work, the therapeutic effects? Decreases BP and HR.
Contraindications: Hypersensitivity to β-blockers, cardiogenic shock, heart block (2nd and 3rd degree), sinus bradycardia,
pheochromocytoma, sick sinus syndrome
Nursing Care/Monitoring: Monitor BP, ECG, and pulse before beginning treatment and periodically thereafter. Check apical/radial pulse
before administration (withhold <50bpm). Notify prescriber of any significant changes. Monitor I&O and DW; Assess for HF signs (JVD,
crackles bilaterally, dyspnea, peripheral edema).
Common Side Effects: Fatigue, weakness, depression, colitis, cramps, diarrhea, constipation, flatulence, dry mouth, hiccups, dizziness,
hallucinations, anxiety, headaches, confusion, insomnia, sore throat, dry burning eyes, impotence, rash, increased liver enzymes
Life Threatening Side Effects: Bronchospasm, pulmonary edema, bradycardia, heart failure
Dosage: 300mg po
Action: Mechanism of action is not known. May affect transport of amino acids across and stabilize neuronal membranes
Why is patient taking the medication? To manage pain
IV push medication (rate of administration and dilution)
IV infusion (infusion rate and compatibilities)
How does the medication work, the therapeutic effects? Put in terms your patient would understand.it will help to reduce the pt. pain
Contraindications: All patients (may ↑ risk of suicidal thoughts/behaviors);
Renal insufficiency (↓ dose and/or ↑ dosing interval if CCr ≤60 mL/min);
Nursing Care/Monitoring: Monitor closely for notable changes in behavior that could indicate the emergence or worsening of suicidal
thoughts or behavior or depression
Life Threatening Side Effects Stevens-Johnson syndrome, toxic epidermal necrolysis, or erythema multiforme. Aplastic anemia,
agranulocytosis
Dosage: 5mg po
Action - Reduces tonic somatic muscle activity at the level of the brainstem. Structurally similar to tricyclic antidepressants.
Why is patient taking the medication? Helps with muscular pain
IV push medication (rate of administration and dilution
IV infusion (infusion rate and compatibilities)
How does the medication work, the therapeutic effects? Put in terms your patient would understand- relieves musculoskeletal pain
Contraindications: Should not be used within 14 days of MAO inhibitor therapy;
Immediate period after MI;
Severe or symptomatic cardiovascular disease;
Cardiac conduction disturbances;
Hyperthyroidism.
Nursing Care/Monitoring: Assess patient for pain, muscle stiffness, and range of motion before and periodically throughout therapy.
Dosage: 10mg po
Action: May have a direct and local effect on GI smooth muscle, reducing motility and tone.
Nursing Care/Monitoring - Assess for symptoms of irritable bowel syndrome (abdominal cramping, alternating constipation and
diarrhea, mucus in stools) before and periodically during therapy.
Assess patient routinely for abdominal distention and auscultate for bowel sounds. If constipation becomes a problem, increasing
fluids and adding bulk to the diet may help alleviate the constipating effects of the drug.
Common Side Effects - confusion, delirium, drowsiness, light-headedness (IM only), psychosis
Nursing Care/Monitoring: Do not allow grapefruit juice, monitor EKG, monitor for QT interval prolongation, abnormal lifer function
test
Common Side Effects: Tremors, dizziness, vision problems, halos around lights, weak and tired, N&V, constipation, numbness
tingling
Life Threatening Side Effects:
Peak: 3-7 hours Onset: 2-3 days (up to 2-3 months) Duration: weeks- months
Evaluation: Did this medication work for the intended purpose? How? Why? (this is not just a yes/no question)
D
Generic Name Dextrose
Brand Name Glucose
Classification carbohydrates, caloric sources
Dosage: 25 ml IV Q15m PRN
Action:Provide calories Prevention of hypoglycemia
Why is patient taking? Patient is weak and undernourished
How does the medication work, the therapeutic effects? Put in terms your patient would understand. This is to add calories to patient
diet
Contraindications allergy to corn or corn products, known diabetic patients
Nursing Care/Monitoring Assess patient’s hydration status, monitor Ins and Outs, assess electrolyte concentrations.
Common Side Effects fluid overload, hypokalemia, hypomagnesemia, hypophosphatemia, glycosuria, hyperglycemia
Life Threatening Side Effects electrolyte imbalance
Peak: rapid Onset: rapid Duration: brief
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question) The medication is
used to improve the caloric intake of patient who was having difficulty consuming enough due to dysphagia. This was improving the
patient’s intake.
E
Generic Name Enoxaparin
Brand Name Lovenox
Classification anticoagulant
Dosage: 1 mg
Action: potentiates inhibitory effect of antithrombin on factor Xa and thrombin
Why is patient taking? To prevent thrombus formation
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Will help prevent blood clots
Contraindications hypersensitivity, active bleeding
Nursing Care/Monitoring assess for signs of bleeding and hemorrhage
Common Side Effects dizzy, headache, insomnia, nausea, vomiting, bleeding, anemia
Life Threatening Side Effects bleeding, anemia
Peak: 3-6 hr Onset: unknown Duration: 12 hr
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question)
Nursing Care/Monitoring assess for cause of deficiency, monitor for constipation or diarrhea, monitor for toxicity or overdose -
stomach pain, fever, nausea, vomiting, bluish lips, fingernails, palms
Common Side Effects constipation, diarrhea
Life Threatening Side Effects iron toxicity or overdose or anaphylactic shock
Peak: 7-10 days Onset: 4 days Duration 2-4 months
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question) The patient is
suffering from failure to thrive and has an iron deficiency so the supplement is being used to improve his level.
Generic Name: Famotidine
Brand Name: Pepcid
Classification:
Therapeutic: antiulcer agent
Pharmacologic: histamine H antagonist
2
Classification:
Therapeutic: diuretic
Pharmaceutical: loop-diuretic
Action: inhibits the reabsorption of sodium and chloride from the loop of Henle and distal renal tubule. Increases renal excretion of
water, sodium, chloride, magnesium, potassium, and calcium.
How does the medication work, the therapeutic effects? Put in terms your patient would understand.
This medication will help with extra fluid in your body. It is supposed to help with swelling throughout your body, and it will cause
you to use the restroom more frequently.
Contraindications:
Hypokalemia, hepatic coma or anuria, alcohol intolerant patients, sensitivity to thiazides and sulfonamides
Common Side Effects: Blurred vision, dizziness, headaches, vertigo, hypotension, dehydration, electrolyte imbalance, excess
urination, photosensitivity
Life Threatening Side Effects: Stevens- Johnson syndrome, severe electrolyte imbalance
Evaluation: Did this medication work for the intended purpose? How? Why? (this is not just a yes/no question).
The patient was also on IV Lasix on top of her PO Lasix. When the patient was admitted on 02/13/18 her home health nurse
mentioned that the patient has had an 18 lbs weight gain since being discharged in January. The patient was also diagnosed with
severe anasarca. When I performed my assessment, the patient did show 2+ pitting in both lower extremities. The medication is given
to help with the fluid retention and she does not seem to be struggling to breathe I believe it has helped relieve the struggle to breathe
caused by the fluid in the lungs. I feel that the fluid buildup is so severe that this medication is not able to provide enough relief for the
patient, but if the patient was not taking this medication her 18 Ibs weight gain could have been more. Especially when she is already
at the max recommended dose and cannot receive more due to her present etiology.
Generic Name: Furosemide
Brand Name: Lasix
Classification:
Therapeutic: diuretic
Pharmaceutical: loop-diuretic
Dosage: 40 mg PO twice daily
Action: inhibits the reabsorption of sodium and chloride from the loop of Henle and distal renal tubule. Increases renal excretion of
water, sodium, chloride, magnesium, potassium, and calcium.
Why is patient taking? Decrease BP and to promote mobilization of excess fluid
How does the medication work, the therapeutic effects? Put in terms your patient would understand.
This medication will help with extra fluid in your body. It is supposed to help with swelling throughout your body, and it will cause
you to use the restroom more frequently.
Contraindications:
Hypokalemia, hepatic coma or anuria, alcohol intolerant patients, sensitivity to thiazides and sulfonamides
Nursing Care/Monitoring: watch for ototoxicity, BUN level may increase
Geriatric: have a higher risk of side effects at regular dose: monitor electrolytes, hypotension
Common Side Effects: Blurred vision, dizziness, headaches, vertigo, hypotension, dehydration, electrolyte imbalance, excess
urination, photosensitivity
Life Threatening Side Effects: Stevens- Johnson syndrome, severe electrolyte imbalance
Peak: 1-2 hours Onset: 30-60 minutes Duration:6-8 hours
Evaluation: Did this medication work for the intended purpose? How? Why? (this is not just a yes/no question).
The patient was also on IV Lasix on top of her PO Lasix. When the patient was admitted on 02/13/18 her home health nurse mentioned that the
patient has had an 18 lbs weight gain since being discharged in January. The patient was also diagnosed with severe anasarca. When I performed
my assessment, the patient did show 2+ pitting in both lower extremities. The medication is given to help with the fluid retention and she does
not seem to be struggling to breathe I believe it has helped relieve the struggle to breathe caused by the fluid in the lungs. I feel that the fluid
buildup is so severe that this medication is not able to provide enough relief for the patient, but if the patient was not taking this medication her
18 Ibs weight gain could have been more. Especially when she is already at the max recommended dose and cannot receive more due to her
present etiology.
G
Generic Name Glucose
Brand Name Dextrose
Classification carbohydrate
Dosage: 5% NS IV Q13 hr 20min
Action :provides calories
Why is patient taking? To increase caloric intake, prevent hypoglycemia
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Glucose provides calories while
patient was NPO upon arrival
Contraindications allergy to corn products
Nursing Care/Monitoring assess hydration status, monitor intake, outtake and electrolytes
Common Side Effects fluid overload, electrolyte imbalance
Life Threatening Side Effects
Peak: rapid Onset: rapid Duration: brief
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question)
I
Generic Name Ipratropium
Brand Name Atrovent
Classification anticoagulant, allergy, cold, cough remedy, bronchodilators
Dosage: 0.5 mg intranasal
Action: inhibits cholinergic receptors in bronchial smooth muscle
Why is patient taking? To keep the lungs clear and help prevent pneumonia because patient has been in bed in the hospital for one
month
How does the medication work, the therapeutic effects? Put in terms your patient would understand. To keep the lungs clear
Contraindications hypersensitivity to ipatropium
Nursing Care/Monitoring assess for allergies, and monitor respiratory status
Common Side Effects dizziness, headache, nervousness, blurred vision, GI irritation
Life Threatening Side Effects
Peak: 15 min Onset: unknown Duration: 6-12 hrs
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question) The drug is being
used to keep his lungs clear and so far is successful
J
K
L
Generic Name Latanoprost
Brand Name Xalatan
Classification Prostaglandin Agonist
Dosage: 1 drop per eye
Action: increase outflow of aqueuos humor treatment of open-angle glaucoma
Why is patient taking? glaucoma
How does the medication work, the therapeutic effects? Put in terms your patient would understand.
Contraindications
Nursing Care/Monitoring local irritation
Common Side Effects may change eye color to brown
Life Threatening Side Effects
Peak: Onset: Duration:
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question)
M
Generic Name Magnesium Chloride
Brand Name Slow-Mag
Classification mineral and electrolyte replacement
Dosage: 64 mg before dinner
Action: essential for the activity of many enzymes, neurotransmissions, and muscular excitability. Osmotically active in GI by
drawing water into lumen and causing peristalsis
Why is patient taking? Electrolyte and mineral deficiency
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Need to restore mineralbalances
in the body
Contraindications hypermagnesemia, hypocalcemia
Nursing Care/Monitoring listen to bowel sounds and watch stool because this works like a laxative
Common Side Effects diarrhea
Life Threatening Side Effects diarrhea
Peak: unknown Onset: 3-6 hrs Duration: unknown
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question) working to restore
balance
N
Generic Name: Neurontin
Brand Name: Gabapentin
Classification:
Therapeutic: analgesic adjunct, anticonvulsant, mood stabilizer
Dosage:100 mg PO twice daily
Action: Decreases postherpetic pain, Decreases leg restlessness, diabetic neuropathy
Why is patient taking? Diabetic neuropathy
How does the medication work, the therapeutic effects? Put in terms your patient would understand. This medication is used to help
with the pain you get from your neuropathy
Contraindications: Hypersensitivity
Nursing Care/Monitoring: behavioral changes, assess for location and characteristics of neuropathic pain
Common Side Effects: dizziness, drowsiness
Life Threatening Side Effects: suicidal thoughts
Peak: 2-4 hours Onset: Rapid Duration: 8 hours
Evaluation: Did this medication work for the intended purpose? How? Why? (this is not just a yes/no question). Patient did not
complain of any problems with neuropathy.
P
Generic Name: Pantoprazole
Brand Name: Protonix
Classification:
Therapeutic: antiulcer agent
Pharmacological: proton-pump inhibitor
Dosage: 40 mg PO dailly
Action: Binds to an enzyme in the presence of acidic gastric pH, preventing the final transport of hydrogen ions into the gastric lumen.
Why is patient taking?
How does the medication work, the therapeutic effects? Put in terms your patient would understand.
Will reduce the amount of acid reflux and help with heartburn.
Contraindications: Hypersensitivity to rabeprazole. Do not use if breast feeding
Nursing Care/Monitoring:
Assess patient for epigastric or abdominal pain, for frank or occult blood in stool, emesis, and gastric aspirate.
Labs: Liver function, magnesium levels
Common Side Effects: headaches, diarrhea
Life Threatening Side Effects: allergic reaction, c-diff, kidney problems, trouble breathing.
Peak: unknown Onset: 2.5 hours Duration: 1 week
Evaluation: Did this medication work for the intended purpose? How? Why? (this is not just a yes/no question)
The time that I was with the patient she never complained of any stomach pains or heartburn. I also never saw in her charts that she
had a history of GERD. If the patient is taking this medication for GERD I would believe it is doing what it is supposed to, by
reducing the acid accumulation in the gastric region since the patient never complained of anything related to this treatment.
Generic Name: Potassium chloride
Brand Name: K-Dur
Classification:
Dosage: 20 mEq PO twice daily
Action: replacement prevents potassium deficiency
Why is patient taking? Prevent Hypokalemia
How does the medication work, the therapeutic effects? Put in terms your patient would understand. This medication will help make
sure you have enough potassium in your blood
Contraindications: Hyperkalemia, severe renal impairment, use causiouslt with cardiac disease
Nursing Care/Monitoring: monitor ECG for changes
Common Side Effects: weakness, confusion, ECG changes, diarrhea
Life Threatening Side Effects:
Peak: 1-2 hours Onset: Unknown Duration: Unknown
Evaluation: Did this medication work for the intended purpose? How? Why? (this is not just a yes/no question)
Q
R
S
Generic Name 0.9% normal saline IV
Brand Name
Classification electrolyte
Dosage: 30 ml per hr
Action: rehydrate
Why is patient taking? To gently restore electrolyte balance
How does the medication work, the therapeutic effects? Put in terms your patient would understand.
Contraindications
Nursing Care/Monitoring excessive isotonic fluids can lead to heart failure, renal failure, cushing syndrome
Common Side Effects over hydration – headache, lethargy, confusion, peripheral edema, pulmonary edema, muscle spasms, seizures,
coma
Life Threatening Side Effects
Peak: Onset: Duration:
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question) Yes, in the two days
patient had been administered iv, sodium levels went from 119 to 130
U
V
Generic Name Venlafaxine
Brand Name Effexor
Classification antidepressant, antianxiety
Dosage: 37.5 mg PO daily
Action: selective serotonin/norepinephrine reuptake inhibitors
Why is patient taking? To improve patient’s anxiety
How does the medication work, the therapeutic effects? Put in terms your patient would understand. To help with anxiety
Contraindications concurrent use with MAOIs, cardiovascular disease, impaired renal function
Nursing Care/Monitoring assess mental status and mood changes, especially for suicidal thoughts
Common Side Effects abnormal dreams, anxiety, dizziness, insomnia, weakness, rhinitis, visual disturbances, abdominal pain, GI
upset, sexual dysfunction
Life Threatening Side Effects neuroleptic malignant syndrome, seizures, suicidal thoughts
Peak: 2-4 wks Onset: within 2 wks Duration: unknown
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question) Patient’s mental
status was altered due to cerebrovascular incident therefore, efficacy of Effexor difficult to determine
Pharmacological and Parenteral Therapy(Complete for all scheduled and PRN medications taken in the past
24 hours)
Classification: Statin
Dosage: 20 mg qHS
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Lowers levels of bad cholesterol
and increases levels of good cholesterol.
Nursing Care/Monitoring: avoid grapefruit, provide education pertaining to diet and exercise, reduce risk of plaque build up, provide
smoking cessation, explain importance of follow up exam
How does the medication work, the therapeutic effects? Put in terms your patient would understand.
Decreases blood pressure, reduces heart rate or irregular heart contractions.
Nursing Care/Monitoring: Monitor BP, INO, daily weight, assess edema, dyspnea, JVD
Classification Anticoagulant
Dosage: 5 mg PO BID
Action: Acts as a selective, reversible site inhibitor of factor Xa, inhibiting both free and bound factor. Does not affect platelet
aggregation directly, but does inhibit thrombin-induced platelet aggregation. Decreases thrombin generation and thrombus
development.
How does the medication work, the therapeutic effects? Decrease chances of stroke and blood clots.
Contraindications Previous severe hypersensitivity reactions; Active pathological bleeding; Severe hepatic impairment; Not
recommended for use in patients with prosthetic heart valves; Concurrent use of strong dual inducers of CYP3A4 and P-gp; Lactation:
Should not be used. Renal impairment increases risk of bleed
Nursing Care/Monitoring Assess patient for symptoms of stroke or peripheral vascular disease periodically during therapy.
Evaluation: Did this medication work for the intended purpose? How? Why? No, my patient developed a blood clot in his left lower
leg during hospitalization.
Action: Decrease contractions in smooth muscle of the prostatic capsule by preventing binding to the alpha-adrenergic receptors.
Why is patient taking? Benign Prostatic Hyperplasia to control urgency
How does the medication work, the therapeutic effects? This medication works to decrease frequent and hard urination and urinating
at night.
Contraindications Allergies. Sulfa allergies. Patient’s at risk for prostate carcinoma. Patients undergoing cataract surgery
Nursing Care/Monitoring Monitor symptoms of BPH. Access blood pressure for orthostatic hypotension & syncope. Monitor I&O’s
and daily weight. Access for edema. Rectal exam prior
Common Side Effects Dizziness, headaches, intraoperative floppy iris syndrome, rhinitis, orthostatic hypotension, priapism,
retrograde/diminished ejaculation
Evaluation: Did this medication work for the intended purpose? How? Why? No, the patient had frequent urination.
Dosage: 20 mg PO qday
Action: Inhibits the action of histamine at the H2-receptor site located primarily in gastric parietal cells, resulting in inhibition of
gastric acid secretion.
How does the medication work, the therapeutic effects? Healing and prevention of stomach ulcers. Decrease symptoms of heartburn.
Decreased acidity in the stomach.
Contraindications Hypersensitivity; Some products contain alcohol and should be avoided in patients with known intolerance; Some
products contain aspartame and should be avoided in patients with phenylketonuria.
Nursing Care/Monitoring Access for abdominal pain, blood in stool, emesis, or gastric aspirate. Access for confusion in geriatric
patients. Monitor CBC with differential. May cause false-positive results for urine protein.
Common Side Effects confusion, dizziness, drowsiness, hallucinations, headache. constipation, diarrhea, drug-induced hepatitis,
nausea. Decreased sperm count, gynecomastia, anemia, neutropenia, thrombocytopenia. pain at IM site. hypersensivity reactions,
vasculitis.
Evaluation: Did this medication work for the intended purpose? How? Why? Yes, my patient did not display symptoms of gastric
ulcers or GERD.
Dosage: 80 mg PO qday
Action: Inhibits the reabsorption of sodium and chloride from the loop of Henle and distal renal tubule. Increases renal excretion of
water, sodium, chloride, magnesium, potassium, and calcium. Effectiveness persists in impaired renal function.
How does the medication work, the therapeutic effects? Put in terms your patient would understand. This medication is taken to
increase urination and relieve water weight to decrease blood pressure.
Contraindications Hypersensitivity; Cross-sensitivity with thiazides and sulfonamides may occur; Hepatic coma or anuria; Some
liquid products may contain alcohol, avoid in patients with alcohol intolerance
Nursing Care/Monitoring Monitor fluid status, BP, pulse. Access fall risk and implement fall risk strategies. Access patients receiving
digoxin for adverse effects, Access for tinnitus and hearing loss. Access allergy for sulfonamides. Access for rash.
Common Side Effects blurred vision, dizziness, headache, vertigo. hearing loss, tinnitus. hypotension. anorexia, constipation, diarrhea,
dry mouth, dyspepsia, increased liver enzymes, nausea, pancreatitis, vomiting. Increased bun, excessive urination, nephrocalcinosis.
ERYTHEMA MULTIFORME, STEVENS-JOHNSON SYN- DROME, TOXIC EPIDERMAL NECROLYSIS, photosensitivity,
pruritis, rash, urticaria. hypercholesterolemia, hyperglycemia, hypertriglyceridemia, hyperuricemia. dehydration, hypocalcemia,
hypochloremia, hypokalemia, hypomagnesemia, hyponatremia, hypovolemia, metabolic alkalosis. APLASTIC ANE- MIA,
AGRANULOCYTOSIS, hemolytic anemia, leukopenia, thrombocytopenia. muscle cramps. paresthesia. fever.
Life Threatening Side Effects Stevens-Johnson syndrome, toxic epidermal necrolysis, or erythema multiforme. Aplastic anemia,
agranulocytosis
as
Evaluation: Did this medication work for the intended purpose? How? Why? Yes, decreased edema with urination and blood pressure
within normal range.
Generic Name Prednisone
Dosage: 60 mg PO qAM
How does the medication work, the therapeutic effects? This medication works to suppress your body from attacking itself.
Contraindications Active untreated infections. Lactation: Avoid chronic use; Known alcohol, bisulfite, or tartrazine hypersensitivity or
intolerance (some products contain these and should be avoided in susceptible patients); Administration of live virus vaccines.
Nursing Care/Monitoring Assess for signs of adrenal insufficiency before and periodically during therapy. Monitor intake and output
ratios and daily weights. Observe patient for peripheral edema, steady weight gain, rales/crackles, or dyspnea. Notify health care
professional if these occur. Assess for changes in level of consciousness and headache during therapy. Monitor serum electrolytes and
glucose. May cause hyperglycemia, especially in persons with diabetes. May cause hypokalemia. Patients on prolonged therapy
should routinely have CBC, serum electrolytes, and serum and urine glucose evaluated. Suppress reactions to allergy skin tests.
Periodic adrenal function tests may be ordered to assess degree of hypothalamic-pituitary-adrenal axis suppression in systemic and
chronic topical therapy.
Common Side Effects Depression, Euphoria, headache, personality changes, psychoses, restlessness, cataracts, increased intraocular
pressure, hypertension, acne, decreased wound healing, hirsutism, adrenal suppression, hyperglycemia, hypokalemia,
thrombophlebitis, weight gain, osteoporosis, muscle pain, cushingoid appearance, increased susceptibility of infection
Evaluation: Did this medication work for the intended purpose? How? Why? No, my patient displayed symptoms of rheumatoid
arthritis
Dosage: 40 mg qHS
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Lowers levels of bad cholesterol
and increases levels of good cholesterol.
Nursing Care/Monitoring: avoid grapefruit, provide education pertaining to diet and exercise, reduce risk of plaque build up, provide
smoking cessation, explain importance of follow up exam
Dosage: 20 mg PO qday
Action: Inhibits the action of histamine at the H2-receptor site located primarily in gastric parietal cells, resulting in inhibition of
gastric acid secretion.
How does the medication work, the therapeutic effects? Healing and prevention of stomach ulcers. Decrease symptoms of heartburn.
Decreased acidity in the stomach.
Contraindications Hypersensitivity; Some products contain alcohol and should be avoided in patients with known intolerance; Some
products contain aspartame and should be avoided in patients with phenylketonuria.
Nursing Care/Monitoring Access for abdominal pain, blood in stool, emesis, or gastric aspirate. Access for confusion in geriatric
patients. Monitor CBC with differential. May cause false-positive results for urine protein.
Common Side Effects confusion, dizziness, drowsiness, hallucinations, headache. constipation, diarrhea, drug-induced hepatitis,
nausea. Decreased sperm count, gynecomastia, anemia, neutropenia, thrombocytopenia. pain at IM site. hypersensivity reactions,
vasculitis.
Life Threatening Side Effects arrhythmias, agranulocytosis, aplastic anemia
Evaluation: Did this medication work for the intended purpose? How? Why? Yes, my patient did not display symptoms of gastric
ulcers or GERD.
Dosage: 81 mg
Action: Blocks pain impulses in CNS, reduces inflammation by inhibition of prostaglandin synthesis; antipyretic action results from
vasodilation of peripheral vessels; decreases platelet aggregation
Contraindications: GI bleeding, bleeding disorders, vit K deficiency, peptic ulcer, acute bronchospasm, agranulocytosis, increased
intracranial pressure, intracranial bleeding, nasal polyps, urticaria
Nursing Care/Monitoring: Assess for pain before and 1 hours after administration; assess for edema in feet, ankles, legs; Assess for
ototoxicity; allergic reactions and monitor liver/renal and blood studies.
Common Side Effects: rash, urticaria, bruising, diarrhea, pulmonary edema, dizziness, confusion, rapid pulse, tinnitus, hypo-
glycemia/natremia/kalemia.
Life Threatening Side Effects: Hepatotoxicity: dark urine, clay-colored stools, yellowing of the skin and sclera, itching, abdominal
pain, fever, diarrhea if patients are on long term.
Evaluation: Did this medication work for the intended purpose? How? Why? (this is not just a yes/no question) Yes, there was no
signs of recurrent ischemic attacks.
Dosage: 10 mg
Action: Elevates acetylcholine concentrations (cerebral cortex) by slowing degradation of acetylcholine released in cholinergic
neurons; does not alter underlying dementia
How does the medication work, the therapeutic effects? Put in terms your patient would understand. This medication may help lessen
the effects of dementia association with Alzheimer’s disease. It enhances cognition.
Nursing Care/Monitoring: Monitor B/P, heart rate: hypo/hypertension; Assess mental status: affect, mood, behavioral changes,
depression, complete suicide assessment; Assess GI status: nausea, vomiting, anorexia, diarrhea; Assess GU status: urinary frequency,
incontinence
Common Side Effects: Rash, flushing, diaphoresis, bruising, Frequency, UTI, incontinence, hypo/hypertension, AV block, Dizziness,
insomnia, somnolence, headache, fatigue, abnormal dreams, syncope
Life Threatening Side Effects: Atrial fibrillation, sinus bradycardia, AV block, GI bleeding, seizures
Evaluation: Did this medication work for the intended purpose? How? Why? (this is not just a yes/no question) Yes, while caring for
her she never lost her awareness or orientation.
Dosage: 50 mcg
Action: Controls protein synthesis; increases metabolic rate, cardiac output, renal blood flow, O2 consumption, body temp, blood
volume, growth, development at cellular level via action on thyroid hormone receptors.
Contraindications: Adrenal insufficiency, recent MI, thyrotoxicosis, hypersensitivity to beef, alcohol intolerance
Nursing Care/Monitoring: Take B/P, pulse before each dose; monitor I&O ratio and weight every day in same clothing, using same
scale, at same time of day; Assess for increased nervousness, excitability, irritability, which may indicate a too-high dosage of
medication, usually after 1-3 wk of treatment; check for bleeding, bruising.
Common Side Effects: increased or decreased appetite, cramps, weight loss, heat intolerance, fever and insomnia
Evaluation: Did this medication work for the intended purpose? How? Why? (this is not just a yes/no question) Yes, her thyroid levels
did not drop while in care.
Dosage: 10 mg
Action: Selectively suppresses renin-angiotensin-aldosterone system; inhibits ACE; prevents conversion of angiotensin I to
angiotensin II
How does the medication work, the therapeutic effects? Put in terms your patient would understand. This pill will help lower you BP
Nursing Care/Monitoring: monitor B/P, check for orthostatic hypotension, syncope; check for edema in feet, legs daily, weight daily,
dyspnea, wet crackles; Assess for anaphylaxis, toxic epidermal necrolysis, angioedema, allergic reactions: rash, fever, pruritus,
urticaria; facial swelling, dyspnea, tongue swelling (rare)
Common Side Effects: chest pain, hypotension, vomiting, vertigo, insomnia, headache, sinus tachycardia
Life Threatening Side Effects: stroke, angioedema, anaphylaxis, toxic epidermal necrolysis, hepatic failure and hepatic necrosis
Dosage: 100 mg
Action: Lowers B/P by β-blocking effects; reduces elevated renin plasma levels; blocks β2-adrenergic receptors in bronchial, vascular
smooth muscle only at high doses, negative chronotropic effect
How does the medication work, the therapeutic effects? Put in terms your patient would understand.
Contraindications: Hypersensitivity to β-blockers, cardiogenic shock, heart block (2nd and 3rd degree), sinus bradycardia,
pheochromocytoma, sick sinus syndrome
Nursing Care/Monitoring: Monitor B/P during beginning treatment, periodically thereafter; pulse q4hr; note rate, rhythm, quality;
check apical/radial pulse before administration; notify prescriber of any significant changes (pulse <50 bpm); Assess for edema in
feet, legs daily; monitor I&O, daily weight; check for jugular vein distention, crackles bilaterally, dyspnea (CHF); Monitor skin
turgor, dryness of mucous membranes for hydration status, especially geriatric
Common Side Effects: Colitis, cramps, diarrhea, constipation, flatulence, dry mouth, hiccups, dizziness, hallucinations, anxiety,
headaches, confusion, insomnia, sore throat, dry burning eyes, impotence, and rash
Life Threatening Side Effects: Agranulocytosis, eosinophilia, thrombocytopenic purpura, cardiac arrest, AV block, bradycardia,
pulmonary/peripheral edema, chest pain
Evaluation: Did this medication work for the intended purpose? How? Why? (this is not just a yes/no question) Yes, BP was kept
within a suitable range per doctors’ orders.
Action: Potent inhibitor of neuronal serotonin and norepinephrine uptake, weak inhibitor of dopamine; no muscarinic, or histaminergic
How does the medication work, the therapeutic effects? Put in terms your patient would understand. This medication is given as a
preventative measure of anxiety, which will help with the tremors you may have.
Nursing Care/Monitoring: Monitor B/P (lying, standing), pulse q4hr; if systolic B/P drops 20 mm Hg hold product, notify prescriber;
take vital signs q4hr in patients with CV disease; Check weight qwk; weight loss or gain; appetite may increase, peripheral edema may
occur; Monitor urinary retention, constipation; constipation is more likely to occur in children or geriatric
Common Side Effects:Dysphagia, colitis, abnormal vision, ear pain, dry eyes, migraines, syncope, thrombophlebitis, and hypertension
Life Threatening Side Effects: Agranulocytosis, aplastic anemia, neutropenia, pancytopenia, abnormal bleeding, rectal hemorrhage,
uterine hemorrhage, vaginal hemorrhage, and angioedema (ext rel)
Classification: Anticoagulants
Dosage: 2.5 mg
Action: selectively blocks active site of factor Xa, inhibiting blood coagulation (factor Xa inhibitor)
Why is patient taking? To prevent any blood clots that may form d/t blood pooling
How does the medication work, the therapeutic effects? Put in terms your patient would understand.
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question)
Action: Lower blood glucose by: stimulating glucose uptake in skeletal muscle and fat, inhibiting hepatic glucose production. Other
actions: inhibition of lypolysis and proteolysis, enhanced protein synthesis. These are rapid-acting insulins with a more rapid onset and
shorter duration than regular insulin; should be used with an intermediate or long-acting insulin.
Why is patient taking? Control of hyperglycemia in patients with type 1 or type 2 diabetes mellitus.
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Control of high blood sugar due
to diabetes
Contraindications Hypoglycemia; Allergy or hypersensitivity to a particular type of insulin, preservatives, or other additives.
Nursing Care/Monitoring
Assess for symptoms of hypoglycemia (anxiety; restlessness; tingling in hands, feet, lips, or tongue; chills; cold sweats; confusion;
cool, pale skin; difficulty in concentration; drowsiness; nightmares or trouble sleeping; excessive hunger; headache; irritability;
nausea; nervousness; tachycardia; tremor; weakness; unsteady gait) and hyperglycemia (confusion, drowsiness; flushed, dry skin;
fruit-like breath odor; rapid, deep breathing, polyuria; loss of appetite; nausea; vomiting; unusual thirst) periodically during
therapy.
● Monitor body weight periodically. Changes in weight may necessitate changes in insulin dose.
● Assess patient for signs of allergic reactions (rash, shortness of breath, wheezing, rapid pulse, sweating, low BP) during therapy.
● Lab Test Considerations: May cause decreased serum inorganic phosphate, magnesium, and potassium levels.
● Monitor blood glucose every 6 hr during therapy, more frequently in ketoacidosis and times of stress. A1C may also be monitored
every 3 – 6 mo to determine effectiveness.
● Toxicity and Overdose: Overdose is manifested by symptoms of hypoglycemia. Mild hypoglycemia may be treated by ingestion of
oral glucose. Severe hypoglycemia is a life-threatening emergency; treatment consists of IV glucose, glucagon, or epinephrine. Early
signs of hypoglycemia may be less pronounced by long duration of diabetes, diabetic nerve disease, and use of beta blockers; may
result in loss of consciousness prior to patient’s awareness of hypoglycemia.
Evaluation: Did this medication work for the intended purpose? How? Why? This medication was not given during his hospitalization
because blood glucose was controlled.
Action: Inhibits the production of uric acid by inhibiting the action of xanthine oxidase.
How does the medication work, the therapeutic effects? Put in terms your patient would understand. To prevent gout attacks
Contraindications Hypersensitivity
Nursing Care/Monitoring
● Monitor intake and output ratios. Decreased kidney function can cause drug accumulation and toxic effects. Ensure that patient
maintains adequate fluid intake (minimum 2500 – 3000 mL/day) to minimize risk of kidney stone formation.
● Assess patient for rash or more severe hypersensitivity reactions. Discontinue allopurinol immediately if rash occurs. Therapy
should be discontinued permanently if reaction is severe. Therapy may be reinstated after a mild reaction has subsided, at a lower dose
(50 mg/day with very gradual titration). If skin rash recurs, discontinue permanently.
● Gout: Monitor for joint pain and swelling. Addition of colchicine or NSAIDs may be necessary for acute attacks. Prophylactic doses
of colchicine or an NSAID should be administered concurrently during the first 3 – 6 months of therapy because of an increased
frequency of acute attacks of gouty arthritis during early therapy.
● Lab Test Considerations: Serum and urine uric acid levels usually begin to decrease 2 – 3 days after initiation of oral therapy.
● Monitor blood glucose in patients receiving oral hypoglycemic agents. May cause hypoglycemia.
● Monitor hematologic, renal, and liver function tests before and periodically during therapy, especially during the first few mo. May
cause increased serum alkaline phosphatase, bilirubin, AST, and ALT levels. Decreased CBC and platelets may indicate bone marrow
depression. Increased BUN, serum creatinine, and CCr may indicate nephrotoxicity. These are usually reversed with discontinuation
of therapy.
Common Side Effects CV: hypotension, flushing, hypertension, bradycardia, and heart failure (reported with IV administration). CNS:
drowsiness. GI: diarrhea, hepatitis, nausea, vomiting. GU: renal failure, hematuria. Derm: rash (discontinue drug at first sign of rash),
urticaria. Hemat: bone marrow depression. Misc: hypersensitivity reactions.
Life Threatening Side Effects bone marrow depression and heart failure
Evaluation: Did this medication work for the intended purpose? How? Why? Yes, patient did not display any evidence of gout attack.
Generic Name Sevelamer
Action: A polymer that binds phosphate in the GI tract, preventing its absorption.
How does the medication work, the therapeutic effects? Decreased serum phosphate levels in the blood.
Nursing Care/Monitoring
● Assess patient for GI side effects periodically during therapy.
● Monitor serum phosphorus, calcium, bicarbonate, and chloride levels periodically during therapy.
Common Side Effects diarrhea, dyspepsia, vomiting, choking (tablet), constipation, dysphagia (tablet), flatulence, nausea.
Evaluation: Did this medication work for the intended purpose? How? Why? Yes, patient did not have a high serum phosphate level.
Classification Anticoagulant
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Blood clot prevention, prevention
of stroke
Contraindications Hypersensitivity to specific agents or pork products; cross-sensitivity may occur; Some products contain sulfites or
benzyl alcohol and should be avoided in patients with known hypersensitivity or intolerance; Active major bleeding; History of
heparin-induced thrombocytopenia
Nursing Care/Monitoring
Common Side Effects CNS: dizziness, headache, insomnia. CV: edema. GI: constipation, increased liver enzymes, nausea, vomiting.
GU: urinary retention. Derm: alopecia, ecchymoses, pruritus, rash, urticaria. Hemat: BLEEDING, anemia, eosinophilia,
thrombocytopenia. Local: erythema at injection site, hematoma, irritation, pain. MS: osteoporosis. Misc: fever.
Evaluation: Did this medication work for the intended purpose? How? Why? Yes, the patient did not suffer an embolism, heart attack,
or stroke.
Classification Antianginals
Dosage: 60 mg PO qDay
Action: Produce vasodilation (venous greater than arterial). Decrease left ventricular end-diastolic pressure and left ventricular end-
diastolic volume (preload). Net effect is reduced myocardial oxygen consumption. Increase coronary blood flow by dilating coronary
arteries and improving collateral flow to ischemic regions.
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Treatment of acute chest pain
Nursing Care/Monitoring
● Assess location, duration, intensity, and precipitating factors of anginal pain.
● Monitor BP and pulse routinely during period of dosage adjustment.
● Excessive doses may increase methemoglobin concentrations.
Common Side Effects CNS: dizziness, headache. CV: hypotension, tachycardia, paradoxic bradycardia, syncope. GI: nausea,
vomiting. Misc: flushing, tolerance.
Evaluation: Did this medication work for the intended purpose? How? Why? The patient was not given this medication because his
systolic blood pressure was <100 mmHg.
Generic Name Pantoprazole
Dosage: 40 mg PO qDay
Action: Binds to an enzyme in the presence of acidic gastric pH, preventing the final transport of hydrogen ions into the gastric lumen
Why is patient taking? Diminished accumulation of acid in the gastric lumen, with lessened acid reflux. Healing of duodenal ulcers
and esophagitis. Decreased acid secretion in hypersecretory conditions.
How does the medication work, the therapeutic effects? Prevention of GI ulcers.
Contraindications Hypersensitivity; OB: Should be used during pregnancy only if clearly needed; Lactation: Discontinue breast
feeding due to potential for serious adverse reactions in infants.
Nursing Care/Monitoring
● Assess patient routinely for epigastric or abdominal pain and for frank or occult blood in stool, emesis, or gastric aspirate.
● May cause abnormal liver function tests, including increased AST, ALT, alkaline phosphatase, and bilirubin.
● May cause hypomagnesemia. Monitor serum magnesium prior to and periodically during therapy.
Common Side Effects CNS: headache. GI: PSEUDOMEMBRANOUS COLITIS, abdominal pain, diarrhea, eructation, flatulence.
Endo: hyperglycemia. F and E: hypomagnesemia (especially if treatment duration 3 mo). MS: bone fracture.
Evaluation: Did this medication work for the intended purpose? How? Why? Yes, patient did not have any acid reflux symptoms and
did not display evidence of gastric ulcer.
Action: Maintain acid-base balance, isotonicity, and electrophysiologic balance of the cell. Activator in many enzymatic reactions;
essential to transmission of nerve impulses; contraction of cardiac, skeletal, and smooth muscle; gastric secretion; renal function;
tissue synthesis; and carbohydrate metabolism.
Why is patient taking? hypokalemia
How does the medication work, the therapeutic effects? To restore levels of potassium
Contraindications Hyperkalemia; Severe renal impairment; Untreated Addison’s disease; Severe tissue trauma; Hyperkalemic familial
periodic paralysis; Some products may contain tartrazine (FDC yellow dye #5) or alcohol; avoid using in patients with known
hypersensitivity or intolerance; Potassium acetate injection contains aluminum, which may become toxic with prolonged use to high
risk groups (renal impairment, premature neonates).
Nursing Care/Monitoring
● Assess for signs and symptoms of hypokalemia (weakness, fatigue, U wave on ECG, arrhythmias, polyuria, polydipsia) and
hyperkalemia
● Monitor pulse, BP, and ECG periodically during IV therapy.
● Monitor serum potassium before and periodically during therapy. Monitor renal function, serum bicarbonate, and pH. Determine
serum magnesium level if patient has refractory hypokalemia; hypomagnesemia should be corrected to facilitate effectiveness of
potassium replacement. Monitor serum chloride because hypochloremia may occur if replacing potassium without concurrent
chloride.
● Toxicity and Overdose: Symptoms of toxicity are those of hyperkalemia (slow, irregular heart- beat; fatigue; muscle weakness;
paresthesia; confusion; dyspnea; peaked T waves; depressed ST segments; prolonged QT segments; widened QRS complexes; loss of
P waves; and cardiac arrhythmias).
● Treatment includes discontinuation of potassium, administration of sodium bicarbonate to correct acidosis, dextrose and insulin to
facilitate passage of potassium into cells, calcium salts to reverse ECG effects (in patients who are not receiving digoxin), sodium
polystyrene used as an exchange resin, and/ or dialysis for patient with impaired renal function.
Common Side Effects CNS: confusion, restlessness, weakness. CV: ARRHYTHMIAS, ECG changes. GI: abdominal pain, diarrhea,
flatulence, nausea, vomiting; tablets, capsules only, GI ulceration, stenotic lesions. Local: irritation at IV site. Neuro: paralysis,
paresthesia.
Life Threatening Side Effects arrhythmias and ECG changes
Evaluation: Did this medication work for the intended purpose? How? Why? The patient was not given this medication because his
potassium was within normal ranges.
Classification Benzodiazepines
Action: Acts at many levels in the CNS, producing generalized depression. Effects may be mediated by GABA, an inhibitory
neurotransmitter.
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Sleep relief
Contraindications Hypersensitivity; Cross-sensitivity with other benzodiazepines may exist; Pre-existing CNS depression; Severe
uncontrolled pain; Angle- closure glaucoma; Impaired respiratory function; Sleep apnea
Nursing Care/Monitoring
● Assess mental status (orientation, mood, behavior) and potential for abuse prior to administering medication.
● Assess sleep patterns before and periodically throughout therapy.
● Prolonged high-dose therapy may lead to psychological or physical dependence. Restrict amount of drug available to patient,
especially if patient is depressed or suicidal or has a history of addiction.
● Geri: Assess CNS effects and risk of falls. Institute falls prevention strategies.
Common Side Effects CNS: abnormal thinking, behavior changes, hangover, dizziness, drowsiness, hallucinations, lethargy,
paradoxic excitation, sleep driving. EENT: blurred vision. GI: constipation, diarrhea, nausea, vomiting. Derm: rash. Misc: physical
dependence, psychological dependence, tolerance.
Evaluation: Did this medication work for the intended purpose? How? Why? Yes, the patient suffered from insomnia, but it was
relieved nightly by this medication.
Action: Inhibits the synthesis of prostaglandins that may serve as mediators of pain and fever, primarily in the CNS. Has no significant
anti-inflammatory properties or GI toxicity.
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Pain and fever relief
Contraindications Previous hypersensitivity; Products containing alcohol, aspartame, saccharin, sugar, or tartrazine (FDC yellow dye
#5) should be avoided in patients who have hypersensitivity or intolerance to these compounds; Severe hepatic impairment/active liver
disease.
Nursing Care/Monitoring
● Assess overall health status and alcohol usage before administering acetaminophen. Patients who are malnourished or chronically
abuse alcohol are at higher risk of developing hepatotoxicity with chronic use of usual doses of this drug.
● Assess amount, frequency, and type of drugs taken in patients self-medicating, especially with OTC drugs. Prolonged use of
acetaminophen increases the risk of adverse renal effects. For short-term use, combined doses of acetaminophen and salicylates should
not exceed the recommended dose of either drug given alone. Do not exceed maximum daily dose of acetaminophen when considering
all routes of administration and all combination products containing acetaminophen.
● Pain: Assess type, location, and intensity prior to and 30 – 60 min following administration.
● Fever: Assess fever; note presence of associated signs (diaphoresis, tachycardia, and malaise).
● Evaluate hepatic, hematologic, and renal function periodically during prolonged, high-dose therapy.
● May alter results of blood glucose monitoring.
● Increased serum bilirubin, LDH, AST, ALT, and prothrombin time may indicate hepatotoxicity.
● Toxicity and Overdose: If overdose occurs, acetylcysteine (Acetadote) is the antidote.
Common Side Effects CNS: agitation (IV), anxiety (IV), headache (IV), fatigue (IV), insomnia (IV). Resp: atelectasis (IV), dyspnea
(IV). CV: hypertension (IV), hypotension (IV). GI: constipation (IV), INCREASED liver enzymes, nausea (IV), vomiting (IV). F and
E: hypokalemia (IV). GU: renal failure (high doses/ chronic use). Hemat: neutropenia, pancytopenia. MS: muscle spasms (IV), trismus
(IV)
Life Threatening Side Effects hepatotoxicity, ACUTE GENERALIZED EXANTHEMATOUS PUSTULOSIS, STEVENS-
JOHNSON SYNDROME, TOXIC EPIDERMAL NECROLYSIS,
Evaluation: Did this medication work for the intended purpose? How? Why? Yes, patient was pain free.
Generic Name magnesium hydroxide/aluminum hydroxide
Classification Antacids
Dosage: 30 mL PO g4hr
Action: Neutralize gastric acid following dissolution in gastric contents. Inactivate pepsin if pH is raised to greater than or equal to 4.
Why is patient taking? Neutralization of gastric acid with healing of ulcers and decrease in associated pain.
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Relief of heartburn, indigestion,
and GERD
Contraindications Severe abdominal pain of unknown cause, especially if accompanied by fever; Renal failure, Products containing
tartrazine or sugar in patients with known intolerance.
Nursing Care:
● Antacid: Assess for heartburn and indigestion as well as location, duration, character, and precipitating factors of gastric pain.
● Monitor serum phosphate, potassium, and calcium levels periodically during chronic use. May cause increase serum calcium
and decrease serum phosphate concentrations.
Common Side Effects constipation, diarrhea, hypermagnesemia, hypophosphatemia
Peak: 30 min Onset: slightly delayed Duration: 30 min-1 hour (empty stomach) 3 hr (after meals)
Evaluation: Did this medication work for the intended purpose? How? Why? Yes, patient did not complain of heartburn, indigestion,
or GERD.
Classification Laxatives
Dosage: 10 mg PO qDay
Action: Stimulates peristalsis. Alters fluid and electrolyte transport, producing fluid accumulation in the colon.
Contraindications Hypersensitivity; Abdominal pain; Obstruction; Nausea or vomiting (especially with fever or other signs of an acute
abdomen).
Nursing Care/Monitoring
● Assess patient for abdominal distention, presence of bowel sounds, and usual pattern of bowel function.
● Assess color, consistency, and amount of stool produced.
Common Side Effects GI: abdominal cramps, nausea, diarrhea, rectal burning. F and E: hypokalemia (with chronic use). MS: muscle
weakness (with chronic use). Misc: protein- losing enteropathy, tetany
Evaluation: Did this medication work for the intended purpose? How? Why? The patient was not given this medication because he did
not complain of constipation.
Action: Promotes incorporation of water into stool, resulting in softer fecal mass. May also promote electrolyte and water secretion
into the colon.
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Softening and passage of stool.
Contraindications Hypersensitivity; Abdominal pain, nausea, or vomiting, especially when associated with fever or other signs of an
acute abdomen.
Nursing Care/Monitoring
● Assess patient for abdominal distention, presence of bowel sounds, and usual pattern of bowel function.
● Assess color, consistency, and amount of stool produced.
Common Side Effects EENT: throat irritation. GI: mild cramps, diarrhea. Derm: rashes.
Classification
Action: Increases coronary blood flow by dilating coronary arteries and improving collateral flow to ischemic regions. Produces
vasodilation (venous greater than arterial). Decreases left ventricular end-diastolic pressure and left ventricular end-diastolic volume
(pre- load). Reduces myocardial oxygen consumption.
Why is patient taking? Relief or prevention of anginal attacks. Increased cardiac output. Reduction of BP.
How does the medication work, the therapeutic effects? Chest pain attacks
Contraindications: Hypersensitivity; Severe anemia; Pericardial tamponade; Constrictive pericarditis; Alcohol intolerance (large IV
doses only); Concurrent use of PDE-5 inhibitor (sildenafil, tadalafil, vardenafil).
Nursing Care/Monitoring
● Assess location, duration, intensity, and precipitating factors of patient’s anginal pain.
● Monitor BP and pulse before and after administration. Patients receiving IV nitroglycerin require continuous ECG and BP
monitoring. Additional hemodynamic parameters may be monitored.
● Lab Test Considerations: May cause increased urine catecholamine and urine vanillylmandelic acid concentrations.
● Excessive doses may cause increased methemoglobin concentrations.
● May cause falsely increase serum cholesterol levels.
Common Side Effects: dizziness, headache, apprehension, restlessness, weakness. EENT: blurred vision. CV: hypotension,
tachycardia, syncope. GI: abdominal pain, nausea, vomiting. Derm: contact dermatitis (transdermal). Misc: alcohol intoxication (large
IV doses only), cross-tolerance, flushing, tolerance.
Evaluation: Did this medication work for the intended purpose? How? Why? The patient was not given this medication because he did
not complain of chest pain.
Action: selectively blocks active site of factor Xa, inhibiting blood coagulation (factor Xa inhibitor)
Why is patient taking? We have you take this drug to prevent any blood clots that may form d/t blood pooling in the heart.
How does the medication work, the therapeutic effects? Put in terms your patient would understand.
Nursing Care/Monitoring:
Assess patient for symptoms of stroke or peripheral vascular disease periodically during therapy.
Instruct patient to take apixaban as directed. Take missed doses as soon as remembered on the same day and resume twice
daily administration; do not double doses.
Do not discontinue without consulting health care professional.
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question) Yes, because when I
came in on Saturday the patient was discharged.
Dosage: 25 mg BID
Action: Blocks stimulation of beta1(myocardial) and beta2 (pulmonary, vascular, and uterine)-adrenergic receptor sites. Also has
alpha1 blocking activity, which may result in orthostatic hypotension.
Why is patient taking? Hypertension. HF (ischemic or cardiomyopathic) with digoxin, diuretics, and ACE inhibitors. Left ventricular
dysfunction after myocardial infarction.
How does the medication work, the therapeutic effects? Put in terms your patient would understand. This medication decreased heart
rate and BP, Improves cardiac output, slowing of the progression of HF and decreases risk of death.
Contraindications History of serious hypersensitivity reaction (Stevens-Johnson syndrome, angioedema, anaphylaxis); Pulmonary
edema; Cardiogenic shock; bradycardia, heart block or sick sinus syndrome (unless a pacemaker is in place); Uncompensated HF
requiring IV inotropic agents (wean before starting carvedilol); Severe hepatic impairment; Asthma or other bronchospastic disorders.
Nursing Care/Monitoring
● Monitor BP and pulse frequently during dose adjustment period and periodically during therapy. Assess for orthostatic hypotension
when assisting patient up from supine position.
● Monitor intake and output ratios and daily weight. Assess patient routinely for evidence of fluid over- load (peripheral edema,
dyspnea, rales/crackles, fatigue, weight gain, jugular venous distention). Patients may experience worsening of symptoms during
initiation of therapy for HF.
Common Side Effects CNS: dizziness, fatigue, weakness, anxiety, depression, drowsiness, insomnia, memory loss, mental status
changes, nervousness, nightmares. EENT: blurred vision, dry eyes, intraoperative floppy iris syndrome, nasal stuffiness. Resp:
bronchospasm, wheezing. GI: diarrhea, constipation, nausea. GU: erectile dysfunction, decreased libido. Derm: itching, rashes,
urticaria. Endo: hyperglycemia, hypoglycemia. MS: arthralgia, back pain, muscle cramps. Neuro: paresthesia. Misc: drug-induced
lupus syndrome.
Life Threatening Side Effects BRADYCARDIA, HF, PULMONARY EDEMA. STEVENS-JOHNSON SYNDROME, TOXIC
EPIDERMAL NECROLYSIS, ANAPHYLAXIS, ANGIOEDEMA
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question)
Pharmacological and Parenteral Therapy (Complete for all scheduled and PRN medications)
Why is patient taking? Diminished accumulation of acid in the gastric lumen, with lessened acid reflux. Healing of duodenal ulcers
and esophagitis. Decreased acid secretion in hypersecretory conditions.
How does the medication work, the therapeutic effects? Prevention of GI ulcers.
Contraindications Hypersensitivity; OB: Should be used during pregnancy only if clearly needed; Lactation: Discontinue breast
feeding due to potential for serious adverse reactions in infants.
Nursing Care/Monitoring
● Assess patient routinely for epigastric or abdominal pain and for frank or occult blood in stool, emesis, or gastric aspirate.
● May cause abnormal liver function tests, including increased AST, ALT, alkaline phosphatase, and bilirubin.
● May cause hypomagnesemia. Monitor serum magnesium prior to and periodically during therapy.
Common Side Effects CNS: headache. GI: PSEUDOMEMBRANOUS COLITIS, abdominal pain, diarrhea, eructation, flatulence.
Endo: hyperglycemia. F and E: hypomagnesemia (especially if treatment duration 3 mo). MS: bone fracture.
Life Threatening Side Effects Psuedomembranous Colitis
Peak: Unknown Onset: 2.5 hr Duration: 1 week
Evaluation: Did this medication work for the intended purpose? How? Why? Patient was discharged by the day of clinical, so I
administered medication to a different patient
Pharmacological and Parenteral Therapy (Complete for all scheduled and PRN medications)
Generic Name Sertraline
Brand Name Zoloft
Classification selective serotonin reuptake inhibitors (SSRIs)
Dosage: 100 mg PO qDay
Action: Inhibits neuronal uptake of serotonin in the CNS, thus potentiating the activity of serotonin. Has little effect on norepinephrine
or dopamine.
Why is patient taking? Major depressive disorder
How does the medication work, the therapeutic effects? Put in terms your patient would understand. This medication will decrease
feelings of depression and decrease incidence of panic attacks.
Contraindications Hypersensitivity; Concurrent use of MAO inhibitors or MAO-like drugs (linezolid or methylene blue); Concurrent
use of pimozide; Oral concentrate contains alcohol; avoid in patients with known intolerance.
Nursing Care/Monitoring
● Assess for suicidal tendencies, especially during early therapy. Restrict amount of drug available to patient
● Monitor appetite and nutritional intake. Weigh weekly. Notify health care professional of continued weight loss. Adjust diet as
tolerated to support nutritional status.
● Assess for serotonin syndrome (mental changes [agitation, hallucinations, coma], autonomic instability [tachycardia, labile BP,
hyperthermia], neuromuscular aberrations [hyperreflexia, incoordination], and/or GI symptoms [nausea, vomiting, diarrhea]),
especially in patients taking other serotonergic drugs (SSRIs, SNRIs, triptans).
● Monitor mood changes. Inform health care professional if patient demonstrates significant increase in anxiety, nervousness, or
insomnia.
Common Side Effects CNS: dizziness, drowsiness, fatigue, headache, insomnia, agitation, anxiety, confusion, emotional lability,
impaired concentration, manic reaction, nervous- ness, weakness, yawning. EENT: pharyngitis, rhinitis, tinnitus, visual abnormalities.
CV: chest pain, palpitations. GI: diarrhea, dry mouth, nausea, abdominal pain, altered taste, anorexia, constipation, dyspepsia,
flatulence, increased appetite, vomiting. GU: sexual dysfunction, menstrual disorders, urinary disorders, urinary frequency. Derm:
increased sweating, hot flashes, rash. Endo: diabetes. F and E: hyponatremia. MS: back pain, myalgia. Neuro: tremor, hypertonia,
hypoesthesia, paresthesia, twitching. Misc:, fever, thirst.
Life Threatening Side Effects NEUROLEPTIC MALIGNANT SYNDROME, SUICIDAL THOUGHTS, SEROTONIN
SYNDROME
Peak: UNKNOWN Onset: within 2-4 weeks Duration: UNKNOWN
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question)
● Antacid: Assess for heartburn and indigestion as well as location, duration, character, and precipitating factors of gastric pain.
● Monitor serum phosphate, potassium, and calcium levels periodically during chronic use. May cause increase serum calcium and
decrease serum phosphate concentrations.
Action: Blocks stimulation of the beta1-adrenergic myocardial receptors to decrease BP and HR.
How does the medication work, the therapeutic effects? Decreases BP and HR.
Contraindications: Hypersensitivity to β-blockers, cardiogenic shock, heart block (2nd and 3rd degree), sinus bradycardia,
pheochromocytoma, sick sinus syndrome
Nursing Care/Monitoring: Monitor BP, ECG, and pulse before beginning treatment and periodically thereafter. Check apical/radial pulse
before administration (withhold <50bpm). Notify prescriber of any significant changes. Monitor I&O and DW; Assess for HF signs (JVD,
crackles bilaterally, dyspnea, peripheral edema).
Common Side Effects: Fatigue, weakness, depression, colitis, cramps, diarrhea, constipation, flatulence, dry mouth, hiccups, dizziness,
hallucinations, anxiety, headaches, confusion, insomnia, sore throat, dry burning eyes, impotence, rash, increased liver enzymes
Life Threatening Side Effects: Bronchospasm, pulmonary edema, bradycardia, heart failure
Dosage: 300mg po
Action: Mechanism of action is not known. May affect transport of amino acids across and stabilize neuronal membranes
Why is patient taking the medication? To manage pain
IV push medication (rate of administration and dilution)
IV infusion (infusion rate and compatibilities)
How does the medication work, the therapeutic effects? Put in terms your patient would understand.it will help to reduce the pt. pain
Contraindications: All patients (may ↑ risk of suicidal thoughts/behaviors);
Renal insufficiency (↓ dose and/or ↑ dosing interval if CCr ≤60 mL/min);
Nursing Care/Monitoring: Monitor closely for notable changes in behavior that could indicate the emergence or worsening of suicidal
thoughts or behavior or depression
Dosage: 10mg po
Action - Antagonizes the effects of histamine at H1 -receptor sites; does not bind to or inactivate histamine.
Anticholinergic effects are minimal and sedation is dose related.
Why is patient taking the medication? To mange inflammatory response
IV push medication (rate of administration and dilution
IV infusion (infusion rate and compatibilities)
How does the medication work, the therapeutic effects? Put in terms your patient would understand- helps to reduce allergy symptoms
Contraindications: Hypersensitivity to cetirizine, hydroxyzine or any component;
Lactation: Excreted in breast milk; not recommended for use.
Nursing Care/Monitoring: May cause dizziness and drowsiness. Caution patient to avoid driving or other activities requiring alertness
until response to medication is known.
Advise patient to avoid taking alcohol or other CNS depressants concurrently with this drug.
Common Side Effects - dizziness, drowsiness (significant with doses >10 mg/day), fatigue
Dosage: 150mg po
Action: Decreases neuronal reuptake of dopamine in the CNS.
Diminished neuronal uptake of serotonin and norepinephrine (less than tricyclic antidepressants).
Why is patient taking the medication? To manage symptoms of depression
IV push medication (rate of administration and dilution)
IV infusion (infusion rate and compatibilities)
How does the medication work, the therapeutic effects? Put in terms your patient would understand- reduces depression
Contraindications - Concurrent use of MAO inhibitors or MAO-like drugs (linezolid or methylene blue);
Concurrent use of ritonavir; Seizure disorder
Nursing Care/Monitoring - Administer doses in equally spaced time increments during the day to minimize the risk of seizures. Risk
of seizures increases fourfold in doses greater than 450 mg per day.
May be initially administered concurrently with sedatives to minimize agitation. This is not usually required after the 1st wk. of
therapy.
Common Side Effects - agitation, headache, aggression, anxiety, delusions, depression, hallucinations, hostility, insomnia, mania,
panic, paranoia, psychoses
Pharmacological and Parenteral Therapy (Complete for all scheduled and PRN medications)
Why is patient taking the medication? Evacuation of the GI tract without water or electrolyte imbalance.
Advise patient to notify health care professional if unusual cramps, bloating, or diarrhea occurs.
Common Side Effects urticarial, abdominal bloating, cramping, flatulence, nausea
Life Threatening Side Effects- none
Pharmacological and Parenteral Therapy (Complete for all scheduled and PRN medications)
Generic Name Insulin Aspart
Brand Name NovoLOG
Classification Antidiabetics, hormone
Dosage: sliding scale subcutaneous injection qidACbedtime
Action: Lower blood glucose by: stimulating glucose uptake in skeletal muscle and fat, inhibiting hepatic glucose production. Other
actions: inhibition of lypolysis and proteolysis, enhanced protein synthesis. These are rapid-acting insulins with a more rapid onset
and shorter duration than regular insulin; should be used with an intermediate- or long-acting insulin.
Why is patient taking? Control of hyperglycemia in patients with type 1 or type 2 diabetes mellitus.
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Control of high blood sugar due
to diabetes
Contraindications Hypoglycemia; Allergy or hypersensitivity to a particular type of insulin, preservatives, or other additives.
Nursing Care/Monitoring Assess for symptoms of hypoglycemia (anxiety; restlessness; tingling in hands, feet, lips, or tongue; chills;
cold sweats; confusion; cool, pale skin; difficulty in concentration; drowsiness; nightmares or trouble sleeping; excessive hunger;
headache; irritability; nausea; nervousness; tachycardia; tremor; weakness; unsteady gait) and hyperglycemia (confusion, drowsiness;
flushed, dry skin; fruit-like breath odor; rapid, deep breathing, polyuria; loss of appetite; nausea; vomiting; unusual thirst) periodically
during therapy.
● Monitor body weight periodically. Changes in weight may necessitate changes in insulin dose.
● Assess patient for signs of allergic reactions (rash, shortness of breath, wheezing, rapid pulse, sweating, low BP) during therapy.
● Lab Test Considerations: May cause decreased serum inorganic phosphate, magnesium, and potassium levels.
● Monitor blood glucose every 6 hr during therapy, more frequently in ketoacidosis and times of stress. A1C may also be monitored
every 3 – 6 mo to determine effectiveness.
● Toxicity and Overdose: Overdose is manifested by symptoms of hypoglycemia. Mild hypoglycemia may be treated by ingestion of
oral glucose. Severe hypoglycemia is a life-threatening emergency; treatment consists of IV glucose, glucagon, or epinephrine. Early
signs of hypoglycemia may be less pronounced by long duration of diabetes, diabetic nerve disease, and use of beta blockers; may
result in loss of consciousness prior to patient’s awareness of hypoglycemia.
Common Side Effects hypoglycemia, erythema, lipodystrophy, pruritus, swelling.
Life Threatening Side Effects HYPOGLYCEMIA and ANAPHYLAXIS.
Peak: 1-2 hours Onset: within 15 minutes Duration: 3-4 hours
Evaluation: Did this medication work for the intended purpose? How? Why? ( this is not just a yes/no question)
Generic Name -lactulose
Brand Name - cholac
Classification - laxative
Dosage: 30 po q8hr
Action: Increases water content and softens the stool.
Lowers the pH of the colon, which inhibits the diffusion of ammonia from the colon into the blood, thereby reducing blood ammonia
levels.
Why is patient taking? To help with bowel movement
How does the medication work, the therapeutic effects? Put in terms your patient would understand. Easily movement of the bowel
Contraindications - Patients on low-galactose diets.
Use Cautiously in:
Diabetes mellitus;
Excessive or prolonged use (may lead to dependence);
Nursing Care/Monitoring - Encourage patients to use other forms of bowel regulation, such as increasing bulk in the diet, increasing
fluid intake, and increasing mobility. Normal bowel habits are individualized and may vary from 3 times/day to 3 times/wk.
Common Side Effects - belching, cramps, distention, flatulence, diarrhea