Pharmaceutical Impurity Analysis Meeting

December 11-12 n Manchester, UK

Waters is holding a special meeting focused on the Analysis of Impurities in Pharmaceuticals. This meeting is relevant for scientists
working on genotoxic, drug-substance related, drug-product-related or process-related impurities. We will discuss current workflows,
major challenges and future trends in pharmaceutical impurity analysis.
During this meeting, attendees will:
• Learn about the latest workflows in impurity analysis
• Receive technology updates relevant to impurity analysis
• Benefit from discussions with scientists experienced in impurity analysis
Register and value the opportunity to spend time with thought leaders from industry, academia, and Waters.

Please REGISTER at your earliest convenience

Wednesday, December 11 to book your free place and ensure your attendance.
12:00 Registration and lunch www.waters.com/impurity
13:00 Introduction
13:15 Overview of Impurity Analysis in the Pharmaceutical Industry
Dr Ute Gerhard, University of Hertfordshire
13:45 Genotoxic Impurities
Dr Richard Ladd, Senior Director, Pharmaceutical and Life Sciences Marketing, Waters Corporation
14:15 Genotoxic Impurities – Quantitative Analysis
TBC Catherine Brookes, Bristol-Myers Squibb Ltd, UK
14:45 New MS Technology Update
Steve Preece, Strategic Technologies Business Development Team Manager, Waters Corporation
15:00 Break
15:30 Parallel Sessions – Please choose 3 sessions upon registration (30 min duration – each will run 3 times)
Round-tables
Informatics in PGI Analysis
PGI Qualitative Analysis using LC/HRMS and GC/HRMS
PGI Quantitative Analysis: LC, GC and SFC Methodologies and Challenges
PGI Method Transfer: Strategies and Challenges
Presentations
Biopharmaceuticals: Monitoring Aggregation
Demonstrations
Software Demonstration - UNIFI®
Using QTof Technology for Impurity Screening
New UPLC® MS Detector
Meeting Solubility Challenges with UPC2®
High Sensitivity Quantitation with MRM UPLC/MS/MS
17:00 End of day 1
 Pharmaceutical Impurity Analysis Meeting
Thursday, December 12
08:45 Introduction to Day 2
09:00 Process Related Impurities: Overview and Challenges
TBC, Waters Corporation
09:30 Process Related Impurities: Qualititative Analysis
Dr Tony Bristow, AstraZeneca, Macclesfield, UK
10:00 Process Related Impurities: Informatics
TBC
10:30 Coffee Break
11:00 Parallel Sessions – Please choose 3 sessions upon registration (30 min duration – each will run 2 times)
Round-tables
Informatics in Process Related Impurity Analysis
Qualititative Analysis of Process Related Impurities
Quantitative Analysis of Process Related Impurities
Presentations
Biopharmaceuticals: Host Cell Protein Identification and Quantitation
Demonstrations
Using QTof Technology for Impurity Screening
New UPLC MS Detector
PATROL UPLC® Laboratory Analyzer
12:00 Lunch
13:00 Drug Substance Related Impurities: Screening
TBC
13:30 Drug Substance Related Impurities
TBC
14:00 Technology Overview for Leachables and Extractables
Baiba Cabovska, Ph.D., Senior Applications Chemist, Waters Corporation
14:15 Parallel Sessions – Please choose 3 sessions upon registration (30 min duration – each will run 3 times)
Coffee Break 14:45-15:15
Round-tables
Informatics for Drug Substance Related Impurities
Quantitative Analysis of Drug Substance Related
Drug Product Related Impurity Analysis
Qualitative Analysis of DS Related Impurities
Presentations
Biopharmaceuticals: Monitoring Protein Degradation using UPLC
Demonstrations
Software Demonstration – Degradation Analysis
Using QTof Technology for Impurity Screening
New UPLC MS Detector
Efficient UPLC Method Development
15:45 Summary of Round-table Discussions
16:15 Meeting Close

©2013 Waters Corporation. Waters, UNIFI, UPLC, UPC2, PATROL UPLC and The Science of What’s Possible are registered trademarks of Waters Corporation.