Name: activity4_muhamad faqih d p_136

Exercise 4: Endocrine System Physiology: Activity 4: Measuring Cortisol and Adrenocorticotropic Hormone Lab Report

Pre-lab Quiz Results

You scored 60% by answering 3 out of 5 questions correctly.

1. Cortisol
Your answer : a. release is stimulated by the hypothalamic hormone ACTH.
Correct answer: d. is a hormone important in the body's response to stress.

2. ACTH
Your answer : b. release is stimulated by increased levels of cortisol.
Correct answer: d. is a tropic hormone that stimulates cortisol release.

3. CRH
You correctly answered: b. has a tropic effect on the anterior pituitary gland.

4. Cushing's syndrome refers to

You correctly answered: c. a hypercortisolism, which could be iatrogenic.

5. A condition of hypocortisolism
You correctly answered: d. refers to low levels of cortisol in the blood.

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Experiment Results
Stop & Think Questions:
Normally high levels of cortisol would inhibit release of
Your answer : a. ACTH
Correct answer: c. both ACTH and CRH

Which hormone(s) stimulate(s) the pituitary gland to release ACTH?

Your answer : b. cortisol
Correct answer: a. CRH

Experiment Data:

Patient Cortisol High/Low ACTH High/Low

(mcg/dl) (pg/ml)
1 2.39 Low 19.43 Low
2 37.43 High 13.04 Low
3 44.64 High 86.65 High
4 2.43 Low 99.95 High
5 49.15 High 19.99 Low

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Post-lab Quiz Results
You scored 16% by answering 1 out of 6 questions correctly.

1. Under normal conditions, if the amount of secreted CRH increases, then

Your answer: d. the development of hypocortisolism is likely.
Correct answer: c. the amount of secreted ACTH will increase.

2. Under normal conditions, if the amount of secreted ACTH increases, then

Your answer: c. a diagnosis of Addison's disease is likely.
Correct answer: d. the amount of secreted CRH will likely decrease.

3. Under normal conditions, if the amount of secreted cortisol increases, then

You correctly answered: b. the amount of secreted ACTH will likely decrease.

4. If a hypersecreting pituitary tumor develops, then an expected outcome is

Your answer: c. hypoglycemia in the blood.
Correct answer: a. a diagnosis of Cushing's disease.

5. If a hypersecreting adrenal cortex tumor develops, then an expected outcome is

You did not answer this question.

Correct answer: b. abnormally low levels of CRH due to negative feedback.

6. A patient's chart lists the diagnosis of Addison's disease. Therefore, you expect
Your answer: a. hypercortisol in the blood.
Correct answer: b. abnormally high levels of ACTH.

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Review Sheet Results
1. Which patient would most likely be diagnosed with Cushing's disease (view Table 4.1 in Experiment Results)? Why?
You did not answer this question.

2. Which two patients have hormone levels characteristic of Cushing's syndrome (view Table 4.1 in Experiment Results)?
You did not answer this question.

3. Patient 2 is being treated for rheumatoid arthritis with prednisone. How does this information change the diagnosis (view
Table 4.1 in Experiment Results)?
You did not answer this question.

4. Which patient would most likely be diagnosed with Addison's disease (view Table 4.1 in Experiment Results)? Why?
You did not answer this question.

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