Solution Compatibility Chart

Invert sug 10%/W/NS

Dextran 6%/D5W/NS

Na Lactate 1/ 6 M
Fruc 10%/W/NS
Intravenous
Medication

D5/1/ 4NS

D5/1/ 2NS
D21/ 2W

D10W

D5NS

D5LR
/ NS
D5W

D5R
NS

LR
12

R
Acetazolamide C C C C C C C C C C C C C C C C
Acyclovir C C C C C C
Aminophylline C C C C C C C C C C C C C C
Antithymocyte C C C C C C C C
Globulin
Ascorbic Acid C C C C C C C C C C C C C C C C
Aztreonam C C C C C C C C C C
Calcium Chloride C C C C C C C C C C
Calcium Gluconate C C C C C C W C
Cefazolin Na C C C C C C C C C W
Cefoperazone Na C C C C C C C
Cefotaxime Na C C C C C C C W C
Cefotetan C C
Cefoxitin Na C C C C C C C C C C C
Ceftazidime C C C C C C C C W C
Ceftriaxone Na C C C C W C
Cefuroxime Na C C C C C C C C W C
Clindamycin C C C C C C C
Dexamethasone C C
Dobutamine HCl C C C C C C C C C
Dopamine HCl C C C C C C C C
Doxycycline C C C W
Epinephrine C C C C C C C C C C C C C C C
Famotidine C C C C
Fentanyl C C
Folic Acid C C
Furosemide C C C C C C C
Gentamicin C C C C C
Heparin Na C C* C C C C* C C C C C C C
Hydrocortisone C C C C
Phosphate
Hydrocortisone C C C C C C C C C C C C C C C C
Na Succinate
Hydromorphone C C C C C C C C C C W C
HCl
Imipenem-Cilastatin C4 C4 C4 C4 C4 C10
Insulin (Regular) CP C C CP C C
Isoproterenol C C P
C C C C CP C C C C C C C C C
Kanamycin C C C C C
Labetalol C C C C C C C C
Lidocaine CP C C C C C C
Magnesium Sulfate C C C
Meperidine HCl C C C C C C C C C C C C C C C C
Meropenem C1 C1 C1 C1 C4 C4 C4 C1 C2

Copyright © 2018 by Elsevier Inc. All rights reserved.

 Invert sug 10%/W/NS
Dextran 6%/D5W/NS

Na Lactate 1/ 6 M
Fruc 10%/W/NS
Intravenous
Medication

D5/1/ 4NS

D5/1/ 2NS
D21/ 2W

D10W

D5NS

D5LR
/ NS
D5W

D5R
NS

LR
12

R
Metoclopramide HCl C C C C C
Morphine C C C C C C C C C C C C C C C C
Multivitamin C C C C C C W C
Nafcillin Na C C C C C C C C C C C
Nitroglycerin C* C C C* C C C C
Norepinephrine CP CP C C
Ondansetron HCl C C C C C C
Oxacillin Na C C C C C C
Pancuronium C C C C C
Papaverine C C C C C C C C C C C C C C
Penicillin G, K C C C C C C C C C C C C C C C
Pentobarbital Na C C* C C C C C C C C C C C C C C
Piperacillin/ C C C* NS
Tazobactam
Potassium Acetate C C C C C
Potassium Chloride C C C C C C C C C C C C C C C C
Potassium Phosphate C C C C C C C C C C C C
Prochlorperazine C C C C C C C C C C C C C C C C
Propranolol CP C C C C C
Pyridoxine HCl C C C C C C C C C C
Ranitidine C C C C C
Sodium Acetate C C C C C C C
Sodium Bicarbonate C C C C C C C C C C C C C C
Sodium Chloride C C C C C C C C C C C C C C C C
Succinylcholine C C C C C C C C C C C C C C C C
Thiamine C C C C C C C C C C C C C C C C
Thiopental C C C C C6 C C C C
Trace Metals C C C C C
Tranexamic Acid C C C C C C C C C
Warfarin C C C C C* C
Zidovudine CP C

This chart is not all inclusive. It is based on manufacturer’s recommendations and Trissel’s.
KEY
C = Compatible* D5R = 5% Dextrose in Ringer’s solution
W = Compatible in water not NS D5LR = 5% Dextrose in Lactated Ringer’s solution
D21/ 2W = 21/ 2% Dextrose in water Dextran 6%/D5W/NS = Dextran 6% in D5W or normal saline
D5W = 5% Dextrose in water Fruc 10%/W/NS = Fructose 10% in water or normal saline
D10W = 10% Dextrose in water Invert sug 10%/W/NS = Invert sugar 10% in water or normal saline
D5/1/ 4NS = 5% Dextrose in 1/ 4 normal saline Na Lactate 1/ 6 M = Sodium lactate 1/ 6 M
D5/1/ 2NS = 5% Dextrose in 1/ 2 normal saline 1
= Stable for 1 hour
2
D5NS = 5% Dextrose in normal saline = Stable for 2 hours
4
NS = Normal saline = Stable for 4 hours
1/ 2NS =  1/ 2 Normal saline 6
= Stable for 6 hours
10
R = Ringer’s solution = Stable for 10 hours
P
LR = Lactated Ringer’s solution = Preferred diluent

*Compatibility in various concentrations may vary; consult pharmacist.

Copyright © 2018 by Elsevier Inc. All rights reserved.