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1- Capnophilic bacteria:
i. Require low concentration of O2
ii. Require high concentration of O2
iii. Require high concentration of CO2
iv. Require low concentration of CO2
v. Require alkaline pH
2- Bacterial cell death is balanced by the formation of new cells
in:
i. Lag phase
ii. Exponential phase
iii. Stationary phase
iv. Decline phase
3- Treatment of bacterial culture with gentamycin, an inhibitor of
protein synthesis, would have maximal effect on:
i. Lag phase
ii. Log phase
iii. Stationary phase
iv. Decline phase
Lecture 1 & 2:
1 b
2 b
3 e
4 d
5 c
Lecture 3:
1 c
2 c
3 b
Lecture 4, 5 &6:
1 b
2 a
3 b
4 c
5 b
6 c
Lecture 7:
1 c
2 c
3 d
4 d
5 a
Lecture 8 & 9:
1 e
2 a
3 d
Lecture 11 & 12 overview of immune system:
4- Vaccination:
i. Is a form of antigen specific-immunostimulation
ii. Is a form of antigen-non-specific-immunostimulation
iii. Does not produce immunity
iv. Aims to increase innate immunity
Lecture 13: Innate immunity & Antigens:
1- Phagocytic cells are characterized by the following Except:
i. Play an important defensive role against established viral
infections
ii. Contain digestive enzymes in lysosomes
iii. Have Fc receptors
iv. Produce hydrogen peroxide to kill phagocytosed
organisms
v. Are attracted to site of infection by chemotactic factors
2- Microbicidal substances present in the body fluids as a part of
the innate humoral defence mechanism include all the
following Except:
i. Lysozyme
ii. Complement
iii. Acute phase proteins
iv. Type I interferon
v. Type II interferon
3- A characteristic of the adaptive immune response but not of
the innate response is:
i. Physical barriers
ii. Chemical barriers
iii. Clonal expansion of the effector cells
iv. Inflammatory mediators
v. Phagocytosis
4- Natural Killer cells:
i. Are important phagocytic cells
ii. Are important APCs
iii. Need antigen-specific MHC activation to kill abnormal
cells
iv. Are important in the late stages of viral infection
v. Have Fc receptors
5- A substance that can evoke an immune response is termed a
(an):
i. Immunogen
ii. Hapten
iii. Epitope
iv. Paratope
v. Adjuvant
6- A hapten:
i. Is usually a high molecular weight substance
ii. Acts as an antigen if coupled to a protein molecule
iii. Is a non-specific potentiator of the immune response
iv. Is capable of inducing immune response alone
v. Determines specificity of an antigen
Lecture 13:
1 a
2 e
3 c
4 e
5 a
6 b
Lecture 14 & 15 T-cell mediated immunity:
KEY
1 B
2 D
3 A
4 B
5 A
6 B
7 C
8 D
9 E
10 D
11 A
Lecture 11 & 12 overview of immune system:
4- Vaccination:
i. Is a form of antigen specific-immunostimulation
ii. Is a form of antigen-non-specific-immunostimulation
iii. Does not produce immunity
iv. Aims to increase innate immunity
Lecture 13: Innate immunity & Antigens:
5- Phagocytic cells are characterized by the following Except:
i. Play an important defensive role against established viral
infections
ii. Contain digestive enzymes in lysosomes
iii. Have Fc receptors
iv. Produce hydrogen peroxide to kill phagocytosed
organisms
v. Are attracted to site of infection by chemotactic factors
6- Microbicidal substances present in the body fluids as a part of
the innate humoral defence mechanism include all the
following Except:
i. Lysozyme
ii. Complement
iii. Acute phase proteins
iv. Type I interferon
v. Type II interferon
7- A characteristic of the adaptive immune response but not of
the innate response is:
i. Physical barriers
ii. Chemical barriers
iii. Clonal expansion of the effector cells
iv. Inflammatory mediators
v. Phagocytosis
8- Natural Killer cells:
i. Are important phagocytic cells
ii. Are important APCs
iii. Need antigen-specific MHC activation to kill abnormal
cells
iv. Are important in the late stages of viral infection
v. Have Fc receptors
9- A substance that can evoke an immune response is termed a
(an):
i. Immunogen
ii. Hapten
iii. Epitope
iv. Paratope
v. Adjuvant
10- A hapten:
i. Is usually a high molecular weight substance
ii. Acts as an antigen if coupled to a protein molecule
iii. Is a non-specific potentiator of the immune response
iv. Is capable of inducing immune response alone
v. Determines specificity of an antigen
Lecture 13:
1 a
2 e
3 c
4 e
5 a
6 b
Lecture 14 & 15 T-cell mediated immunity:
KEY
1 B
2 D
3 A
4 B
5 A
6 B
7 C
8 D
9 E
10 D
11 A
Lecture 16 Cytokines:
1- Type I interferon leads to better killing of virus-infected cells
due to:
i. Increased expression of MHC I molecules
ii. Increased activity of NK cells
iii. Both
iv. Neither
2- Interferon inhibits viral growth primarily by affecting:
i. Host cytokine production
ii. Host protein synthesis
iii. Viral protein synthesis
iv. Viral transcription process
v. Viral assembly and release
3- A product of macrophages that induces an antiviral state in
neighboring cells:
i. Complement
ii. Properdin
iii. Lysozyme
iv. Interferon (IFN)-alpha
v. Interferon (IFN)-gamma
4- Development of Th1 cells is promoted by:
i. IL-12
ii. IL-4
iii. Large doses of antigen
iv. a & c
v. b & c
5- Development of Th2 cells is promoted by:
i. IL-4
ii. Small doses of antigen
iii. Both of the above
iv. Neither of the above
6- The actions of IL-5 are mainly related to:
i. Macrophages
ii. Tc cells
iii. Th cells
iv. Eosinophils
7- The primary role of Th-2 cells is to:
i. Function as T killer cells
ii. Activate macrophages
iii. Activate NK cells
iv. Function as antigen-presenting cells
v. Activate B cells
8- Activation of naïve mature B cells requires the following
Except:
i. Surface antibody contact with antigen
ii. T cell cytokine stimulation
iii. B cell CD40 interaction with T cell CD40L
iv. Expression of IgM and IgD
v. Antigen presentation to T cell via class I MHC
9- For full activation, naïve B cells must receive the following
signal(s):
i. Signal derived from antigen binding to BCR
ii. Signal derived from activated cytotoxic T cells
iii. Signal derived from activated helper T cells
iv. a & b
v. a & c
10- Immunoglobulins:
i. Contain Fc regions derived from both heavy and light
chains
ii. Contain antigen-binding sites derived solely from the
heavy chain
iii. Are produced by both T and B-lymphocytes
iv. When bound to an antigen, may activate proteins of
complement system
Anwers :
1- c
2- c
3- d
4- d
5- c
6- d
7- e
8- e
9- e
10- d
Lecture 17 & 18 Humoral immune response: