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Determinants of patient satisfaction after surgery or corticosteroid injection


for trapeziometacarpal osteoarthritis: Results of a prospective cohort study

Article  in  Archives of Orthopaedic and Trauma Surgery · November 2014


DOI: 10.1007/s00402-014-2119-0 · Source: PubMed

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Arch Orthop Trauma Surg
DOI 10.1007/s00402-014-2119-0

HANDSURGERY

Determinants of patient satisfaction after surgery


or corticosteroid injection for trapeziometacarpal
osteoarthritis: results of a prospective cohort study
Miriam Marks • Laurent Audigé • Lisa Reissner •

Daniel B. Herren • Stephan Schindele •


Thea P. M. Vliet Vlieland

Received: 5 May 2014


Ó Springer-Verlag Berlin Heidelberg 2014

Abstract in the surgical group. In the injection group, a more


Introduction The evaluation of patient satisfaction is advanced Eaton stage of TMC OA and greater pain at
becoming increasingly important in assessing treatment 1 year were associated with reduced satisfaction.
outcomes. The objective of this study was to analyze the Conclusions Surgery for TMC OA leads to high patient
determinants of treatment satisfaction in patients with tra- satisfaction, whereas only half of the patients treated with
peziometacarpal osteoarthritis (TMC OA) after surgery or corticosteroid injection were satisfied with the treatment
corticosteroid injection. result. An advanced stage of TMC OA and higher pain lead
Materials and methods Prospective cohort study of to reduced treatment satisfaction in the latter group, indi-
patients with TMC OA who received surgery or cortico- cating that corticosteroid injection is only effective for
steroid injection was carried out. Socio-demographic and patients in a lower stage of disease. As fulfillment of
clinical data were recorded at baseline and 1 year after the expectations was an important determinant of satisfaction
intervention, and patients filled out the Michigan Hand in the surgical group, we emphasize the need to provide
Outcomes Questionnaire (MHQ). On a 5-point Likert scale, comprehensive information prior to surgery, so that the
patients reported baseline expectations, expectation fulfill- patient’s expectations of treatment outcome are realistic.
ment at 1 year, as well as satisfaction with the treatment
result. To identify determinants of satisfaction, we entered Keywords Carpometacarpal joint  Injection 
these variables into one ordered logistic regression model Osteoarthritis  Satisfaction  Surgery
for surgical patients and another for patients with injection.
Results We included 146 patients, 88 of whom were
treated surgically. With respect to satisfaction at 1 year, Introduction
87 % of the surgical patients were somewhat or very sat-
isfied with the treatment result, whereas only 49 % of the After the distal interphalangeal joints, the trapeziometa-
patients with injection were satisfied. Expectations being carpal (TMC) joint is the hand joint most frequently
fulfilled was the only determinant of treatment satisfaction affected by osteoarthritis (OA) [15]. Treatment strategies
consist of either surgical or conservative management [1].
M. Marks (&)  L. Audigé Trapezium resection with ligament reconstruction and
Department of Research and Development, Schulthess Clinic, tendon interposition (LRTI) is the primary choice for
Lengghalde 2, 8008 Zurich, Switzerland 62–68 % of American hand surgeons who perform surgery
e-mail: Miriam.Marks@kws.ch
for TMC OA [4, 38]. In the conservative treatment of TMC
M. Marks  T. P. M. Vliet Vlieland OA, 89 % of American hand surgeons prefer corticosteroid
Department of Orthopaedics, Leiden University Medical Center, injections [38].
Leiden, The Netherlands Irrespective of the type of intervention, an evaluation of
patient satisfaction is becoming increasingly important in
L. Reissner  D. B. Herren  S. Schindele
Department of Hand Surgery, Schulthess Clinic, assessing treatment outcomes. Satisfied patients are more
Zurich, Switzerland compliant with treatment and are more likely to return to

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the same healthcare provider [23, 28]. However, quanti- In each case, the surgeon chose the treatment strategy in
fying satisfaction is demanding because of the influence of discussion with the patient. Analgesics or hand therapy
a variety of, so far, poorly defined factors on the patient‘s including splinting might have been prescribed additionally
perception of a satisfactory outcome [5, 23]. in both groups, if it was indicated.
In hand surgery, it has been shown that the factors like Some patients were initially treated with injection but
pain and function are associated with treatment satisfac- later decided on surgery. Data available until such time
tion. Furthermore, the appearance of the hand, its strength, were used for the analysis of conservatively treated
range of motion, and expectations fulfilled seem to influ- patients. These patients were not included in the surgical
ence the satisfaction of patients with various hand disorders group in the present analysis to prevent confounding from
[26]. A retrospective study including patients with TMC double inclusion.
OA after implant arthroplasty found that pain, movement,
strength, and functional ability were moderately correlated Outcome measures
with satisfaction [22], but no prospective studies investi-
gating the determinants of patient satisfaction after surgical An independent examiner assessed patients at baseline, and
and conservative management of TMC OA are currently 3, 6, and 12 months after the start of treatment. Socio-
available. demographic and disease-related data were gathered at
The objective of this study was to analyze the deter- baseline. At each study visit, patients underwent a clinical
minants of treatment satisfaction in patients with TMC OA assessment and completed a questionnaire set consisting of
after surgery or corticosteroid injection. the Michigan Hand Outcomes Questionnaire (MHQ) and
the Short Form (SF) 12, version 2.0.
The MHQ, developed by Chung et al. [6], is a hand-
Methods specific questionnaire which yields results for each hand
separately. It consists of 37 items divided into six sub-
This analysis is part of a monocenter, prospective cohort scales: hand function, activities of daily living (ADLs),
study which was carried out in the department of hand pain, work performance, aesthetics, and satisfaction with
surgery of an orthopedic hospital and was approved by the hand function. The psychometric properties of the MHQ
local ethics committee. have been assessed in patients with TMC OA and show
overall good reliability, validity, and responsiveness [25].
Patients and treatment The total score and all six subscale scores are normalized
and range from 0 to 100; higher scores indicate better
The parent study included all patients, with a radiograph- performance, except for the pain subscale, where a higher
ically confirmed diagnosis of TMC OA who underwent score denotes more pain. The German version [19] was
either conservative or surgical treatment for that condition used for this study and the data for the affected hand were
in the months from September 2011 to November 2012. analyzed.
Exclusion criteria were: TMC OA was not the main The SF-12 is a short version of the SF-36 for assessing
problem at the time of consultation, rheumatoid arthritis, quality of life. Its twelve questions give two component
concomitant surgery on other fingers, legal incompetence, summary measures of physical health and mental health.
poor general condition precluding study participation, The scores range from 0 to 100, with higher scores repre-
previous inclusion in this study for the other hand, and senting better health, and the norm value being 50 ± 10
insufficient knowledge of the German language to com- [36]. Although the full version (SF-36) has been investi-
plete the questionnaires. All eligible patients were asked to gated in patients with TMC OA, the SF-12 itself has not
participate by their hand surgeon, and were consecutively [2].
enrolled in the study after they had given written informed Expectations were recorded at baseline. Patients gave
consent. their most important reason for seeking treatment. They
For the present analysis, the surgical group included could choose from a list of 8 predefined reasons, e.g. pain
only patients who received trapeziectomy with LRTI reduction, or add free text. Patients rated their expectation
according to Epping [11], Weilby [37], or Sigfusson and of this reason to be fulfilled after one year on a 5-point
Lundborg [31], whichever method was preferred and rou- Likert scale ranging from ‘totally fulfilled’ to ‘not at all
tinely performed by each surgeon. In some cases, the sur- fulfilled’. At each follow-up, patients were asked if their
geon chose a GraftJacket as interpositional material [20]. expectations regarding the specific reason had been ful-
Additional procedure such as carpal tunnel release was also filled and again they answered on a 5-point Likert scale.
performed, if required. Conservative treatment consisted of At every follow-up visit, we also asked about satisfac-
at least 1 corticosteroid injection. tion with the treatment result, which patients answered on a

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5-point Likert scale ranging from ‘very satisfied’ (5 points) datasets and pooled them using Rubin’s combination rules.
to ‘very dissatisfied’ (1 point). All analyses were done with Stata 12.1.
Key pinch was assessed in a standardized sitting position
using a digital pinch gauge (ELINK, Biometrics Ltd.,
Gwent, UK). We took the average of three measurements Results
on the affected hand for further analysis.
The evaluation of active thumb opposition was based on We included 146 patients in our study, of whom 88 (60 %)
the Kapandji index, ranging from 1 to 10 [16]. Patients try received surgery, while 58 (40 %) patients received an
to touch their fingers with the tip of the thumb. The score is injection (Fig. 1). Fourteen (24 %) patients in the injection
1 when patients are able to touch only the lateral side of the group had surgery during the follow-up period, on average
index finger and 10 when they can reach the volar crease of 7 ± 2.1 months after conservative treatment had started.
the hand. Baseline characteristics for both groups are displayed in
Active MCP I extension was measured with a digital Table 1. At 1 year, data were available from 116 patients,
goniometer (ELINK, Biometrics Ltd., Gwent, UK). which correspond to a follow-up rate of 79 % (Fig. 1).
Standard a/p radiographs of the hand were taken at In both groups, patients showed a significantly improved
baseline, and the severity of OA was graded from stage I hand function after treatment, measured with the MHQ. In
(normal articular contours with joint widening due to lig- the surgical group, the MHQ increased from 46 points at
ament laxity) to stage IV (complete TMC joint deteriora- baseline to 79 at 1 year (p B 0.001), whereas patients in
tion and narrowed, sclerotic scaphotrapezial joint) using the injection group had scores of 59 and 67 points
the Eaton classification [10]. (p = 0.01), respectively (Table 2).
With respect to treatment satisfaction at 1 year, 69
Statistics (87 %) of the surgical patients were somewhat or very
satisfied with the treatment result, whereas only 18 (49 %)
Within-group changes for the abovementioned outcome of the patients in the injection group reported that they
measures over 1 year were calculated using an analysis of were somewhat or very satisfied with the result (Fig. 2).
variance for repeated measures (ANOVA) with Scheffé’s Complications affecting the flexor carpi radialis tendon
post hoc adjustment for multiple comparisons. Differences occurred in three patients after surgery. Two patients
regarding satisfaction between the patients who went to needed surgical revision but were satisfied or very satisfied
surgery following injection compared to those who did not with the treatment result at 1 year. The third patient was
were tested with the Mann–Whitney U test. treated with analgesics and was still dissatisfied after a
We used ordered logistic regression to identify deter- year. At the 3 months follow-up, patients who went to
minants of patient satisfaction. All the outcome measures surgery between 3 and 6 months after injection were not
previously mentioned, at baseline and 1 year were possible less satisfied than those who did not request surgery (sat-
candidates for the regression model, as well as the baseline isfaction score of 3.8 ± 1.8 vs 4.0 ± 1.2; p = 0.995). In
variables of gender, age, duration of thumb complaints, and contrast, those who went to surgery between 6 and
number of previous injections. These variables were first 12 months were less satisfied at the 6 months follow-up
checked for collinearity using the variance inflation factor than patients without subsequent surgery (3.0 ± 1.6 vs
(VIF). A VIF of 5 indicates moderate collinearity and a 4.2 ± 1.1; p = 0.05).
VIF of 10 indicates severe collinearity [3]. We excluded The regression analyses showed that expectations being
variables with a VIF [ 5. The remaining variables were fulfilled was the only determinant of treatment satisfaction
entered into one ordered logistic regression model for at 1 year in the surgical group (Table 3). In the group who
surgical patients and another for patients treated with received injection, a more advanced Eaton stage and
injection, with treatment satisfaction at 1 year being the greater pain at 1 year were associated with reduced satis-
dependent variable. Stepwise backward elimination faction (Table 4).
removed all variables with p [ 0.05, until only variables
with p B 0.05 were left. As some data for the dependent
variable ‘‘treatment satisfaction at 1 year’’ were missing, Discussion
we imputed such data, based on the assumption that values
were missing at random (MAR). Multiple imputation is an The results of this cohort study on the determinants of
accepted statistical technique to reduce bias due to missing satisfaction in patients with TMC OA showed that 87 % of
data and is justified by statistical theory and simulation the surgical patients were satisfied with treatment at 1 year,
studies [7, 17, 32]. A multiple imputation model was built whereas only half of the patients treated with corticosteroid
containing relevant baseline data. We created 20 imputed injection were satisfied at this time. The fulfillment of

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Fig. 1 Patient recruitment diagram

Table 1 Baseline characteristics of 146 patients stratified by In this non-randomized study, we saw that patients
treatment treated with a corticosteroid injection had a better func-
Characteristics Surgery Conservative tional status at baseline and shorter duration of complaints
(n = 88) (n = 58) than patients scheduled for surgery. Despite the better pre-
conditions of the conservatively treated patients, these
Female, no. (%) 78 (89) 46 (79)
patients were less satisfied with the treatment result than
Age (years) 63.2 ± 9.1 64.4 ± 9.8
patients who were operated. Furthermore, although being
Patients taking drugs for thumb pain, 40 (45) 12 (21)
no (%)
statistically significant, the change in the MHQ score
between baseline and 1 year in the injection group was
Number of drugs per week for thumb 7.9 ± 5.9 8.5 ± 7.8
pain only 8 points. As this change is below the value of 17
Duration of complaints (months) 45 ± 55 24 ± 21 points for the minimum important change (MIC) [25], we
Eaton stage of osteoarthritis 2.9 ± 0.7 2.7 ± 0.5 can assume that this result is not clinically meaningful for
Intervention, no. the patients. This suggestion is in accordance to other
Trapeziectomy and LRTI 80 studies who found that corticosteroid injections can indeed
Trapeziectomy and LRTI and CTS 6 significantly reduce pain but only in the short term, with a
release single injection being effective for about 4 weeks up to
Trapeziectomy and LR and 2 6 months [14, 18, 21, 33].
interposition with GraftJacket The decision for the treatment strategy was made indi-
Corticosteroid injection 58 vidually for each of our patients. Our hand surgeons usu-
If not otherwise indicated, the mean ± standard deviation is given ally prefer to treat patients with only mild complaints
LRTI ligament reconstruction and tendon interposition, CTS carpal
conservatively, but suggest surgery to patients with severe
tunnel syndrome pain and restrictions in their daily life. This approach is
similar to that in other studies recommending surgery in
cases where pain limits the activities of daily living or
expectations was an important determinant of treatment when conservative treatment fails [1, 8, 39].
satisfaction in the surgical group, while a more advanced Our results show, that expectations being fulfilled is a
Eaton stage and greater pain at 1 year were associated with strong determinant of treatment satisfaction in the surgical
reduced satisfaction in the injection group. group. An association between expectations fulfilled and

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Table 2 Results of the outcome Outcome measure Surgery p value Conservative p value
measures at baseline and 1 year
Baseline 1 year Baseline 1 year

MHQ total score (0–100, 100 = best) 46 ± 15 79 ± 16 £0.001 59 ± 13 67 ± 16 0.010


SF-12 Physical Health (0–100, 37 ± 7.9 46 ± 10 £0.001 40 ± 8.3 40 ± 9.2 0.520
100 = best, 50 = norm)
SF-12 Mental Health (0–100, 50 ± 13 53 ± 11 0.091 50 ± 12 50 ± 10 0.985
100 = best, 50 = norm)
MHQ Michigan Hand Outcomes Kapandji Index (0–10, 10 = best) 8.4 ± 1.8 9.0 ± 1.1 0.005 9.1 ± 1.1 8.9 ± 1.5 0.930
Questionnaire, SF-12 Short Key pinch (kg) 3.0 ± 1.9 3.6 ± 1.8 0.012 4.4 ± 2.2 3.9 ± 2.2 0.445
Form 12 questionnaire, MCP Active MCP extension (°) 7.8 ± 11 12 ± 8.9 £0.001 11 ± 10 11 ± 9.5 0.758
metacarpophalangeal joint I

Fig. 2 Treatment satisfaction of surgical and conservatively treated patients at different times of follow-up

Table 3 Results of the ordered logistic regression on treatment sat- Table 4 Results of the ordered logistic regression on treatment sat-
isfaction at 1 year for surgical patients isfaction at 1 year for patients treated with corticosteroid injection
Coefficient Standard p value 95 % Coefficient Standard p value 95 %
error confidence error confidence
interval interval

Expectations 3.17 0.62 B0.001 1.95–4.38 Eaton stage of -2.00 0.68 0.003 -3.34 to
fulfilled at osteoarthritis -0.66
1 year MHQ pain score -0.08 0.02 B0.001 -0.12 to
at 1 year -0.04
MHQ Michigan Hand Outcomes Questionnaire
patient satisfaction has also been reported for patients after
MCP arthroplasty [30]. In patients after carpal tunnel
release, it has been shown that expectations being met and Shoulder and Hand questionnaire (DASH) scores. The
a generally optimistic view of health accounted for 31 % of association between expectations and satisfaction revealed
the variability in postoperative Disabilities of Arm, in our study substantiates the relevance of the decision-

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making process (i.e. shared decision making) prior to a developed questionnaires, statistical comparisons between
surgery. It is important that the physician is aware of the studies are not possible [26]. One focus should be the
patient’s expectations to ensure that the patient makes development of a standardized assessment tool for routine
realistic assumptions about the possible treatment outcome use in clinical practice to evaluate patients’ expectations
[27, 35]. prior to treatment, fulfillment of expectations, and satis-
In patients treated with injection, a more severe stage of faction at the end of treatment.
TMC OA and higher residual pain determined lower Based on our results, we can conclude that surgery for
patient satisfaction, indicating that corticosteroid injection TMC OA leads to high patient satisfaction, whereas only half
is only effective for patients with a lower stage of disease. of the patients treated with a corticoid injection were satisfied
These findings are substantiated by other studies, where with the treatment result. An advanced stage of TMC OA and
patients with stage I or II TMC OA obtain greater and more higher pain lead to reduced treatment satisfaction in the latter
sustained benefit from conservative treatment than patients group indicating that corticosteroid injection is only effec-
with more severe TMC OA [9, 18]. Furthermore, tive for patients with a lower stage of disease. After surgery,
researchers recommend surgery in cases where pain limits expectations being fulfilled is a strong determinant of treat-
the activities of daily living or when conservative treatment ment satisfaction. This highlights the need to evaluate
fails [1, 8, 39]. expectations and provide patients with comprehensive
In a systematic review of determinants of patient satis- information prior to any intervention, to ensure that their
faction after any orthopedic intervention to the hand, it was expectations of the treatment outcome are realistic.
found that other parameters, such as esthetics, range of
motion, or strength may influence satisfaction [26]. How- Acknowledgments We would like to thank Dr. Meryl Clarke for
her support in preparing the manuscript, Prof. Dr. Rob Nelissen and
ever, we did not find any of these variables to be a deter- Dr. Jörg Goldhahn for their contributions during study planning, Dr.
minant of satisfaction in our groups. We suggest that the Sebastian Kluge and Dr. Silvia Kündig for their contributions to
appearance of the hand may not be as important to patients patient recruitment, and Stefanie Hensler and Franziska Kohler for
with TMC OA as it is, for example, to patients with their assistance in data collection.
rheumatoid arthritis [12, 24]. Regarding the so-called
objective outcomes, there is conflicting evidence in the
literature, to what extent they indeed influence patient References
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