Exercise 10: Acid-Base Balance: Activity 4: Respiratory Responses to Metabolic Acidosis and Metabolic Alkalosis Lab

Report

Pre-lab Quiz Results

You scored 100% by answering 4 out of 4 questions correctly.

1. An increase in metabolic rate (without compensation) would result in

You correctly answered: a. more carbon dioxide in the blood.

2. Excessive vomiting results in

You correctly answered: c. loss of acid, metabolic alkalosis.

3. Which of the following is not acidic?

You correctly answered: d. antacids

4. Which of the following decreases the rate of metabolism?

You correctly answered: b. lowered body temperature

010/21/18 page 1
Experiment Results
Predict Question:
Predict Question 1: What do you think will happen when the metabolic rate is increased to 80 kcal/hr?
Your answer : c. respiratory acidosis

Predict Question 2: What do you think will happen when the metabolic rate is decreased to 20 kcal/hr?
Your answer : d. Breaths per minute will decrease.

Stop & Think Questions:

The tidal volume and breaths per minute increased with increased metabolism because
You correctly answered: b. there is more carbon dioxide being formed.

Which body system is compensating for the metabolic alkalosis?

You correctly answered: c. respiratory

Experiment Data:

Metabolic Rate BPM (breaths/min) Blood pH PCO2 [H+] [HCO3-]

(kcal/hr) in Blood in Blood
50 15 7.40 40 40 24
60 17 7.34 45 47 20
80 21 7.24 55 63 14.50
40 13 7.46 37 38 26
20 9 7.52 31 32 30

010/21/18 page 2
010/21/18 page 3
010/21/18 page 4
Post-lab Quiz Results
You scored 100% by answering 4 out of 4 questions correctly.

1. What happened to the breathing when metabolism was increased?

You correctly answered: d. The breaths per minute and the tidal volume increased.

2. Which of the following is not a cause of metabolic acidosis?

You correctly answered: b. constipation

3. If PCO2 in the blood increases, then

You correctly answered: a. [H+ ] increases and pH decreases.

4. Which of the following values increased with decreased metabolism?

You correctly answered: d. pH and [HCO3- ]

010/21/18 page 5
Review Sheet Results
1. Describe what happened to the blood pH when the metabolic rate was increased to 80 kcal/hr. What body system was
compensating? How well did the results compare with your prediction?
Your answer:
Como podemos observar en el experimento, el Ph de la sangre a 80 Kcal/h disminuye obteniendo un Ph de 7.23, dando
lugar a una acidosis respiratoria. presenta compensación respiratoria porque aumenta la PCO2.

2. List and describe some possible causes of metabolic acidosis.

Your answer:
Las causas de la acidosiss metabólica son las siguientes:
- Fallo renal para excretar H+
- Pérdida de bases ( diarrea)
- Formación de ácidos excesivos en anaerobiosis severa ( acidosis láctica)
- Derviados del metabolismo anómalo de aminoácidos y grasas ( cetacidosis), diabetes mellitus

3. Describe what happened to the blood pH when the metabolic rate was decreased to 20 kcal/hr. What body system was
compensating? How well did the results compare with your prediction?
Your answer:
Si observamos el experimento vemos que cuando la tasa metabólica sufre una disminución hasta 20 Kcal/h, se produce un
aumento del Ph hasta 7.53.
El sistema encargado de compensarlo es el respiratorio, disminuye las respiraciones por minute porque la ppresión parcial
del dióxido de carbono baja.

4. List and describe some possible causes of metabolic alkalosis.

Your answer:
Las causas que pueden dar lugar a una alcalosis metabólica son las siguientes:
- Ingestión excesiva de drogas alcalinas (antiácidos conteniendo HCO3).
- Vómito excesivo de ácidos estomacales.
-Diarreas.
- Abuso de laxantes

010/21/18 page 6