Sei sulla pagina 1di 19

Pharmacy and Biotechnology

Department of Pharmaceutical Technology

Pharmaceutics I
PHTC 311

Tutorial 4: Pharmaceutical Solutions

Course Instructors:
Prof. Dr. Samar Mansour
Dr. Salma Tammam
Dr. Mai Rady

Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 1


Aqueous Pharmaceutical Solutions
1. Gargles

Gargles are aqueous solutions used for treating the pharynx (throat) and nasopharynx mild infections (i.e.
soreness in mild throat infections)

They have antiseptic, astringent, anesthetic and soothing effects.

Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 2


Mouthwashes and gargles Contains:

. Anti- infective Anesthetic


Astringent Flavours Alcohols
agent:

Eucalyptus Chloroform Preservative


Phenol gum Peppermint
water action
Oil

Zinc
Hexitidine chloride Co-solvent
Cinnamon for flavour
Oil
Povidone
iodine
Colour Surfactant
Humectants
Solubilize the
flavour Glycerol
Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 3
Gargles
Phenol Gargle:

Rx

Phenol Anti- Infective Agent

Glycerin Increase viscosity – Sweetening Agent

Tartrazine Coloring Agent

Zinc Chloride Astringent

Oil of Peppermint Flavoring Agent

Tween Solubilize the flavor


Water

Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 4


Gargles
Betadine sore throat gargle
kills most bacteria and viruses implicated in sore throat
(pharyngitis)

Povidone Iodine (Anti- infective agent)

Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 5


Aqueous Pharmaceutical Solutions
2. Mouth Washes

Mouthwashes can be used for therapeutic & cosmetic purposes


(I) Therapeutic mouthwashes can be formulated to reduce plaque, gingivitis, dental caries and stomatitis.

(II) Cosmetic mouthwashes may be formulated to reduce bad breath through the use of antimicrobial
and/or flavoring agents. used to clean and refresh the buccal cavity

Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 6


Mouth Washes
Hydrocortisone

Nystatin Stomatitis

Tetracycline

Tranexamic acid Bleeding

Hexitidine Anti-Infective Agent


Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 7
Aqueous Pharmaceutical Solutions
3. Douches

Douche is an aqueous solution, which is directed against a part or into a cavity of


the body

It functions as a Cleansing or Antiseptic agent.

Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 8


Aqueous Pharmaceutical Solutions
3. Douches

1. An eye douche: to remove foreign particles and discharges from the eyes.

2. Pharyngeal douches: prepare the interior of the throat for an operation and to
cleanse it.

3. Vaginal douches: antiseptic, astringent, or soothing action.

4. Nasal douches: Compound Sodium Borate Solution is used as pharyngeal or


nasal douche.
Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 9
Douches Contains:

. Anti- infective agent: Astringent Anesthetic Ingredients to


chance pH

Phenol Alum Menthol Na


Bicarbonate

Borax
Zinc Sulphate
Citric Acid

Povidone
iodine

Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 10


Douches

Anti- Infective Agent

pH modifying Agent

Astringent

Anaethetic

Anti- inflamatory

Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 11


Douches

Cyteal Antiseptic foaming solution

Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 12


Aqueous Pharmaceutical Solutions
4. Enamas

(I) Evacuation enemas: used to Evacuate the bowel “stool in constipation or before surgery”.
They act by stimulating peristalsis.

(II) Therapeutic enemas: may contain medicaments required to exert a local effect in the large
bowl (e.g., anthelmintic enemas) to treat worms and parasites (destroy intestinal parasites)

(III) Diagnostic enemas: They contain radiopaque substances for X- ray diagnostic
investigation in the large bowel (e.g., Barium sulfate enema)

Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 13


Enamas

Saline Laxative

Preservative

Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 14


Aqueous Pharmaceutical Solutions

5. Otic Solutions

They are simple solutions of medicaments designed to exert a local effect in


the ear, to soften wax, to treat local inflammation and infections, or to relieve
pain.

Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 15


Otic Solutions Contains:

. Antibiotics Anti-iflamatory Anesthetic Solvents

Benzochaine
Gramicidin Hydrocortisone- Water
Cortisone

Cincochaine Propylene
Framycetin glycol
Sulphate Dexamethasone

Glycerol

Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 16


Otic Solutions

Antibiotic
Anti-inflamatory
Local Anesthetic

Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 17


Videos

https://drive.google.com/file/d/0B2IZKpWyP3-
zX2lFUGtJSUVRaEk/view?usp=drivesdk

https://drive.google.com/file/d/0B2IZKpWyP3-
zR1NkX0E0VnROdEE/view?usp=drivesdk

https://drive.google.com/file/d/0B2IZKpWyP3-
zUUFaVm42ZFFYSGc/view?usp=drivesdk

https://drive.google.com/file/d/0B2IZKpWyP3-
zbktjSnpSNE9TdVE/view?usp=drivesdk

Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 18


Thank you
Pharmaceutical Technology Department - (PHTC 311) – Winter 2017 19

Potrebbero piacerti anche