PHARMACON CLASSES ¥Daily practice test¥ 20th Sep 2018

A leading & best coaching institute for the preparation of competitive exams like DI/DCO, Pharmacists, GPAT, NIPER, DIPSAR etc)

1. Normal and diastolic BP (mm Hg) respectively 12. Antihypertensive agent should be avoided during
a. < 120 & < 80 pregnancy
b. 120-139 & 80-89 a. Clonidine
c. 140-159 or 90-99 b. Hydralazine
d. 160 or > 100 c. Methyl Dopa
2. Which one is a AT1 receptor blockers d. Captopril
a. Temazepam e. Atenolol
b. Talmisartan 13. Angiotensin II causes all except
c. Terazosin a. Stimulate release of ADH
d. Temozolomide b. Increase thirst
3. ACE inhibitor is c. Cause vasodilation
a. Lisinopril d. Stimulate aldosterone release
b. Losartan 14. Calcium blocking agents of used in the treatment of
c. Lacidipine hypertension include
d. Labetalol a. Prazosin
4. Alpha adrenergic blocker which used in the treatment b. Amlodipine
of hypertension c. Losartan
a. Prazosin d. Captopril
b. Terazosin 15. Longest acting nitroglycerin preparation is
c. Doxazosin a. Glycerin trinitrate
d. All of these b. Amyl nitrate
5. Side effect of Spironolactone c. Pentaerythritol tetranitrate
a. Gynecomastia d. Isosorbide dinitrate
b. Impotence 16. Antihypertensive drugs that cause positive comb's
c. Menstrual irregularities test
d. All of these a. Methyldopa
6. Drawback of diuretic as antihypertensive agent b. clonidine
a. Hypokalemia c. hydralazine
b. Carbohydrate intolerance d. All of these
c. Hyperuricemia 17. Treatment of choice of cyanide poisoning
d. Dyslipidemia a. NaHCO3
e. All of these b. KnMNO4
7. Postural hypotension is caused with the following c. Sod nitrate followed by thiosulphate
drugs d. NaCI
a. Prazosin 18. All are Potassium-sparing diuretic except
b. Eplerenone a. Spironolactone
c. Aliskiren
b. Canrenone
d. Hydrochlorothiazide
8. Antihypertensive agent used in cheese reaction c. Triamterene
a. Phentolamine d. Amiloride
b. Perindopril e. Chlorthalidone
c. Propranolol
d. Clonidine 19. Renin is synthesized in
9. Drug of choice in pregnancy to treat hypertension
a. Heart
a. Methylcobalamin
b. Methyldopa b. Lunch
c. Metyrapone c. Kidney
d. Metolazone d. Liver
e. Metoclopramide 20. Minoxidil is a
10. False statement for minoxidil a. Alpha adreno receptor blocker
a. It is prodrug b. Beta adreno receptor blocker
b. Used in alopecia/increased body hair growth c. Direct acting vasodilator
c. Mechanism of action-potassium channel d. Decrease sympathetic activity through train
openers 21. Hypotensive effect of clonidine is due to its
d. Mechanism of action-potassium channel a. Beta adrenergic blocker
blocker b. Alpha adreno receptor blocker
e. It is vasodilator c. H 2 receptor stimulation
11. Which one drug relax is both resistance and d. H2 receptor antagonism
capacitance vessels 22. Methyldopa is
a. Hydralazine a. Antiarrhythmic drug
b. Diazoxide b. Hyperglycemic drug
c. Sodium nitroprusside c. Antihypertensive drug
d. Minoxidil d. Antithyroid drug

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PHARMACON CLASSES ¥Daily practice test¥ 20th Sep 2018
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23. All of the following class of drugs are used to treat 35. In the stability of emulsion which one critically
hypertension except important steps should be prevented
a. Thiazide a. Flocculation
b. Propranolol
b. Breaking
c. Calcium channel blocker
d. NSAIDs c. Creaming
24. ACE inhibitors d. Coalescence
a. Atenolol 36. Tweens are used to prepare the EMULSION OF
b. Ranitidine a. W/O
c. Enalapril b. O/W
d. Propranolol c. Fine emulsion
25. Angiotensin-converting enzyme act on
d. None
a. Angiotensinogen
b. Angiotensin I 37. The HLB system is used to a classification of
c. Angiotensin II a. Colouring Agent
d. Angiotensin III b. Surfactants
26. What is losartan c. BCS classification of drug
a. ACE inhibitors d. Perfumes
b. Angiotensin II receptor antagonist 38. Creaming is a
c. Angiotensin II receptor agonist
a. Reversible process
d. Active metabolite of lisinopril
27. Arterial and venous vasodilator used as b. Irreversible process
antihypertensive c. Both a and b
a. Hydralazine d. None
b. Minoxidil 39. How does emulsifier works
c. Sodium nitroprusside a. By decreasing the interfacial tension
d. Diazoxide
b. By preventing coalescences of dispersed
28. The antihypertensive drug used for hair Regrowth
a. Clonidine globules
b. Nitroprusside c. Both a and b
c. Verapami d. None of these
d. Minoxidil 40. Medically emulsion administered orally are usually
29. Acidic drugs are best observed in a. O/W
a. Stomach b. W/O
b. Mouth
c. Fine emulsion
c. Intestine
d. Absorption in same in all part of GIT d. Micro emulsion
30. First pass effect result in 41. During conduction test for identification of an
a. Increased bioavailability of drugs emulsion, electric circuit completes when
b. Decrease bioavailability of the drugs continuous phase is
c. Increased protein binding of the drugs a. Water
d. Decrease protein binding of the drugs b. Oils
31. Weakly alkaline drug is best absorbed from
c. Coconut oil
a. Stomach
b. Mouth d. Theobroma oil
c. Intestine 42. Very fine emulsion is prepared by
d. Absorption in same in all part of GIT a. Colloidal mill
32. Creaming in oil in water emulsion normally b. Hammer mill
a. Upward c. Silverson mixer homogenizer
b. Downward d. None of these
c. First upward and downward 43. If surfactant have HLB value 4. Which type of
d. None of these emulsion can be prepared using this surfactant
33. On a commercial scale the emulsion is prepared by a. O/W
a. Freezing b. W/O
b. Homogenization c. BOTH
c. Centrifugation d. NONE
d. Dialysis
34. Ideal emulsifying agent should be soluble in
a. Aqueous phase
b. Oily phase
c. Both a and b
d. Insoluble in both phase
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PHARMACON CLASSES ¥Daily practice test¥ 20th Sep 2018
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44. Bancroft rules describe b. Potency

a. Relationship the nature of emulsifying agent and c. Efficacy
type of emulsion formed d. Selectivity
b. Surfactant is more soluble in water-O/W
emulsion
c. Surfactant is more soluble in oil-W/O emulsion 55. Physiological antagonism is
d. All of these a. Isoprenaline and salbutamol
45. Surfactants having HLB value 3-6, favours the b. Isoprenaline and adrenaline
formation of c. Isoprenaline and propranolol
a. O/W d. Adrenaline and histamine
56. The major mechanism of transport of the drug across
b. W/O
a biological membrane is
c. Fine emulsion a. Passive diffusion
d. Micro emulsion b. Facilitated diffusion
46. Surfactant with HLB value 8-16 favours c. Active transport
a. O/W d. Endocytosis
b. W/O 57. All are reversible indirect acting cholinergic drug
c. Fine emulsion except
a. Endrophonium
d. Micro emulsion
b. Donepezil
47. HLB value indicates with reference to surfactant c. Carbochol
a. Hydrophobic lipophilic balance d. Gallantamine
b. Hydrophilic-lipophilic balance 58. Carbamates poisoning can be treated using
c. Hydrophilic lipophilic balance a. Atropine
d. Henson Lanson balance b. Pralidoxime
c. Both
48. HLB term given by
d. None of these
a. Sorensen
b. Griffin
c. CLC
d. SSJ
49. Flocculation of globules in emulsion can be
prevented by
a. Using uniform sized globules
b. Imparting charged on global
c. By adding inert substance
d. Both a and b
50. Antiemetic drug that are safe in pregnancy
a. Doxylamine
b. Metoclopramide
c. Domperidone
d. Mosapride
51. Which of the following is hypnotic drug increase the
activity of hepatic drug metabolism enzyme
a. Phenobarbitone
b. Zolpidem
c. Flurazepam
d. Zaleplon
52. Propertion of solids in concentrate suspension &
dilute suspension is respectively
a. 2-10 %w/v; upto 50 %w/v
b. Upto 50 % w/v; 2-10 % w/v
c. 2 % w/v; 70 % w/v
d. None
53. Mechanism of action of pralidoxime is
a. Stimulation of Ach receptors
b. Inhibition of breakdown of Ach
c. Blockage of Ach release
d. Reactivation of AchE enzym
54. Therapeutic index measures the
a. Safety
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