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SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Revision Date

according to Regulation (EC) No. 1907/2006 Revision Date 08.06.2010 1. Identification of the substance/mixture and of

08.06.2010

1. Identification of the substance/mixture and of the company/undertaking

Product Information

Catalogue No.:

104864

Product name:

Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Use of the Substance/Mixture

Reagent for analysis, Chemical production, Pharmaceutical production and analysis

Company:

Merck KGaA * 64271 Darmstadt * Germany * Phone:+49 6151 72-0

Emergency telephone:

Please contact the regional Merck representation in your country.

Responsible/issuing person:

EQ-EPS * e-mail: prodsafe@merck.de

2. Hazards identification

GHS Classification Carcinogenicity, Category 1B Germ cell mutagenicity, Category 1B Reproductive toxicity, Category 1B

Oxidizing solid, Category 2 Acute toxicity, Category 2, Inhalation Acute toxicity, Category 3, Oral Acute toxicity, Category 4, Dermal Specific target organ toxicity - repeated exposure, Category 1 Skin corrosion, Category 1B Respiratory sensitization, Category 1

Skin sensitization, Category 1 Acute aquatic toxicity, Category 1 Chronic aquatic toxicity, Category 1

H350: May cause cancer. H340: May cause genetic defects. H360FD: May damage fertility. May damage the unborn child. H272: May intensify fire; oxidiser. H330: Fatal if inhaled. H301: Toxic if swallowed. H312: Harmful in contact with skin. H372: Causes damage to organs through prolonged or repeated exposure. H314: Causes severe skin burns and eye damage. H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled. H317: May cause an allergic skin reaction. H400: Very toxic to aquatic life. H410: Very toxic to aquatic life with long lasting effects.

EC Classification

Carc.Cat.2; R45

Mut.Cat.2; R46

Repr.Cat.2; R60 - 61

O; R8

Xn; R21

T+; R26

T; R25 - 48/23

C; R34

R42/43

N; R50/53

For the full text of the R-phrases mentioned in this Section, see Section 16.

Safety Data Sheet according to Regulation (EC) No. 1907/2006

Catalogue No.:

104864

Product name:

Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

3. Composition/information on ingredients

Formula

K₂Cr₂O₇

Cr₂K₂O₇ (Hill)

CAS-No.

7778-50-9

Index-No.

024-002-00-6

EC-No.

231-906-6

Molar mass

294,19 g/mol

4. First aid measures

General advice

First aider needs to protect himself.

After inhalation: fresh air. If breathing stops: immediately apply mechanical ventilation, if necessary oxygen mask. Immediately call in physician.

After skin contact: wash off with plenty of water. Remove contaminated clothing. Call a physician immediately.

After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist.

If swallowed: give water to drink (two glasses at the most). Seek medical advice immediately. In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a 10% slurry) and consult a doctor as quickly as possible.

Notes to physician

Treatment

Carefully clean wounds and cover with sterile dressing material.

5. Fire-fighting measures

Suitable extinguishing media

Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Specific hazards during fire fighting

Not combustible. Has a fire-promoting effect due to release of oxygen.

Special protective equipment for fire-fighters

Do not stay in dangerous zone without self-contained breathing apparatus. In order to avoid contact with skin, keep a safety distance and wear suitable protective clothing.

Further information

Prevent fire extinguishing water from contaminating surface water or the ground water system.

6. Accidental release measures

Personal precautions

Avoid inhalation of dusts in all circumstances. Avoid substance contact. Ensure adequate ventilation.

Environmental precautions

Do not empty into drains.

Safety Data Sheet according to Regulation (EC) No. 1907/2006

Catalogue No.:

104864

Product name:

Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Methods for cleaning up

Take up carefully. Forward for disposal. Clean up affected area. Avoid generation of dusts.

7. Handling and storage

Handling

Advice on safe handling

Work under hood. Do not inhale substance.

Observe label precautions.

Storage

Further information on storage conditions

Tightly closed. Dry. Away from combustible materials and sources of ignition and heat. Keep locked up or in an area accessible only to qualified or authorised persons.

Store at +5°C to +30°C.

8. Exposure controls/personal protection

Personal protective equipment Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances handled. The resistance of the protective clothing to chemicals should be ascertained with the respective supplier.

Respiratory protection

required when dusts are generated. Recommended Filter type: Filter P 3 (acc. to DIN 3181) for solid and liquid particles of toxic and very toxic substances

Hand protection

full contact:

splash contact:

Glove material:

Glove thickness:

Break through time:

Glove material:

Glove thickness:

Break through time:

Nitrile rubber 0,11 mm > 480 min

Nitrile rubber 0,11 mm > 480 min

The protective gloves to be used must comply with the specifications of EC irective 89/686/EEC and he resultant standard EN374, for example. KCL 741 Dermatril® L (full contact), KCL 741 Dermatril® L (splash contact). The breakthrough times stated above were determined by KCL in laboratory tests acc. to EN374 with samples of the recommended glove types. This recommendation applies only to the product stated in the safety data sheet and supplied by us as well as to the purpose specified by us. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE- approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Eye protection

Tightly fitting safety goggles

Protective measures

Protective suit

Safety Data Sheet according to Regulation (EC) No. 1907/2006

Catalogue No.:

104864

Product name:

Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Hygiene measures

Immediately change contaminated clothing. Apply skin- protective barrier cream. Wash hands and face after working with substance. Work under hood. Do not inhale substance.

9. Physical and chemical properties

Form

solid

Colour

orange

Odour

odourless

pH

3,6

at 100 g/l

Viscosity, dynamic

no data available

Melting point

398 °C

Boiling point/boiling range

> 500 °C at 1.013 hPa

Ignition temperature

not applicable

Flash point

not applicable

Oxidizing properties

May intensify fire; oxidiser.

Flammability

no data available

Lower explosion limit

not applicable

Upper explosion limit

not applicable

Vapour pressure

not applicable

Relative vapour density

no data available

Density

2,69 g/cm3 at 20 °C

Bulk density

1.250 kg/m3

Solubility/qualitative

no data available

Water solubility

130 g/l at 20 °C

Partition coefficient: n-

no data available

octanol/water Evaporation rate

no data available

Safety Data Sheet according to Regulation (EC) No. 1907/2006

Catalogue No.:

104864

Product name:

Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

10. Stability and reactivity

Conditions to avoid

Strong heating.

Materials to avoid

Risk of explosion with:

Iron, magnesium, hydrazine and derivatives, hydroxylamine, organic combustible substances

Exothermic reaction with:

Boron, anhydrides, Reducing agents, phosphides

A risk of explosion and/or of toxic gas formation exists with the folllowing substances:

organic combustible substances, glycerol, Sulphides, Acetone, conc. sulfuric acid

Hazardous decomposition products

no information available

Thermal decomposition

ca.500 °C

11. Toxicological information

Acute oral toxicity

LD50 rat Dose: 25 mg/kg

(RTECS) Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation

of the oesophagus and the stomach.

absorption

Acute inhalation toxicity

LC50 rat Dose: 0,094 mg/l, 4 h (IUCLID) Symptoms: mucosal irritations, Cough, Shortness of breath, absorption, Possible damages:, damage of respiratory tract

Acute dermal toxicity

LD50 rat Dose: 1.170 mg/kg (IUCLID)

absorption

Skin irritation

Causes severe burns.

Eye irritation

Causes serious eye damage. Risk of blindness!

Safety Data Sheet according to Regulation (EC) No. 1907/2006

Catalogue No.:

104864

Product name:

Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Sensitisation

Sensitisation test (Magnusson and Kligman):

Result: positive

(IUCLID)

Patch test: human Result: positive (IUCLID)

May cause an allergic skin reaction.

May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Specific target organ toxicity - repeated exposure

Causes damage to organs through prolonged or repeated exposure.

CMR effects

Carcinogenicity:

May cause cancer. Mutagenicity:

May cause genetic defects. Teratogenicity:

May damage the unborn child. Reproductive toxicity:

May damage fertility.

Further information

Chromium (VI) is highly toxic. It is absorbed via both the lungs as well as the gastrointestinal tract. Being strong oxidants, chromates/ bichromates can cause burns and ulcerations on the skin and mucous membranes and also irritations in the upper respiratory tract. Poor tendency for ulcers to heal following penetration of substance into the wound. In predisposed persons the substance rapidly leads to sensitization and allergic reactions of the respiratory tract (risk of pneumonia!) and damage to nasal mucous membranes (under given circumstances perforation of the septum). After swallowing severe symptoms in the gastrointestinal tract such as bloody diarrhoea, vomiting (aspiration pneumonia!) spasms, circulatory collapse, unconsciousness, formation of methaemoglobin. Absorption may result in hepatic and renal damage. Inhalable chromium(VI) compounds have clearly shown themselves to be carcinogenic in animal experiments. Lethal dose (man): 0.5 g. Antidotes:

chelating agents such as EDTA, DMPS (Demaval(R)).

Further data:

This substance should be handled with particular care.

12. Ecological information

Ecotoxicity

Toxicity to fish

LC50

Species: Pimephales promelas (fathead minnow) Dose: 26,13 mg/l Exposure time: 96 h (IUCLID)

Safety Data Sheet according to Regulation (EC) No. 1907/2006

Catalogue No.:

104864

Product name:

Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Toxicity to daphnia and other aquatic invertebrates.

EC50

Species: Daphnia magna (Water flea) Dose: 0,77 mg/l Exposure time: 48 h (in soft water) (IUCLID)

Toxicity to algae

IC50

Species: Chlorella vulgaris (Fresh water algae) Dose: 0,16 - 0,59 mg/l Exposure time: 96 h (IUCLID)

Toxicity to bacteria

MICROTOX-TEST EC50 Species: Photobacterium phosphoreum Dose: 58 mg/l Exposure time: 30 min

Persistence and degradability

Biodegradability

The methods for determining the biological degradability are not applicable to inorganic substances.

Additional ecological information

Do not allow to enter waters, waste water, or soil!

13. Disposal considerations

Product

Chemicals must be disposed of in compliance with the respective national regulations. Under www.retrologistik.de you will find country- and substance-specific information as well as contact partners.

Packaging

Merck product packaging must be disposed of in compliance with the country-specific regulations or must be passed to a packaging return system. Under www.retrologistik.de you will find special information on the respective national conditions as well as contact partners.

14. Transport information

ADR/RID UN 3086 TOXIC SOLID, OXIDIZING, N.O.S. (POTASSIUM DICHROMATE), 6.1 (5.1), II

IATA UN 3086 TOXIC SOLID, OXIDIZING, N.O.S. (POTASSIUM DICHROMATE), 6.1 (5.1), II

IMDG UN 3086 TOXIC SOLID, OXIDIZING, N.O.S. (POTASSIUM DICHROMATE), 6.1 (5.1), II

EmS

The transport regulations re cited according to international regulations and in the form applicable in Germany. Possible national deviations in other countries are not considered.

F-A

S-Q

Safety Data Sheet according to Regulation (EC) No. 1907/2006

Catalogue No.:

104864

Product name:

Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

15. Regulatory information

GHS-Labelling

Hazard pictograms

15. Regulatory information GHS-Labelling Hazard pictograms Signal word Danger Hazard statements H350: May cause cancer.

Signal word

Danger

GHS-Labelling Hazard pictograms Signal word Danger Hazard statements H350: May cause cancer. H340: May cause
GHS-Labelling Hazard pictograms Signal word Danger Hazard statements H350: May cause cancer. H340: May cause
GHS-Labelling Hazard pictograms Signal word Danger Hazard statements H350: May cause cancer. H340: May cause
GHS-Labelling Hazard pictograms Signal word Danger Hazard statements H350: May cause cancer. H340: May cause

Hazard statements

H350: May cause cancer. H340: May cause genetic defects. H360FD: May damage fertility. May damage the unborn child. H272: May intensify fire; oxidiser. H330: Fatal if inhaled. H301: Toxic if swallowed. H312: Harmful in contact with skin. H372: Causes damage to organs through prolonged or repeated exposure. H314: Causes severe skin burns and eye damage. H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled. H317: May cause an allergic skin reaction. H410: Very toxic to aquatic life with long lasting effects.

Precautionary statements

P201: Obtain special instructions before use. P280: Wear protective gloves. P301 + P330 + P331: IF SWALLOWED: rinse mouth. Do NOT induce vomiting. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304 + P341: IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. P308 + P313: IF exposed or concerned: Get medical advice/attention.

Reduced labelling (≤125 ml)

Hazard pictograms

Reduced labelling (≤125 ml) Hazard pictograms Signal word Danger Hazard statements H350: May cause cancer.

Signal word

Danger

Hazard statements

H350: May cause cancer. H340: May cause genetic defects. H360FD: May damage fertility. May damage the unborn child. H330: Fatal if inhaled. H301: Toxic if swallowed. H372: Causes damage to organs through prolonged or repeated exposure. H314: Causes severe skin burns and eye damage. H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled. H317: May cause an allergic skin reaction.

Precautionary statements

The Safety Data Sheets for catalog items are also available at www.merck-chemicals.com

Safety Data Sheet according to Regulation (EC) No. 1907/2006

Catalogue No.:

104864

Product name:

Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

P201: Obtain special instructions before use. P280: Wear protective gloves. P301 + P330 + P331: IF SWALLOWED: rinse mouth. Do NOT induce vomiting. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304 + P341: IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. P308 + P313: IF exposed or concerned: Get medical advice/attention.

Index-No.

024-002-00-6

Labelling according to EC Directives

Symbol(s):

T+

Very toxic

N

Dangerous for the environment

O

Oxidising

R-phrase(s):

45-46-60-61-8-21-

May cause cancer. May cause heritable genetic

25-26-34-42/43-

damage. May impair fertility. May cause harm to the

48/23-50/53

unborn child. Contact with combustible material may cause fire. Also harmful in contact with skin. Also toxic if swallowed. Also very toxic by inhalation. Causes burns. May cause sensitization by inhalation and skin contact. Also toxic: danger of serious damage to health by prolonged exposure through inhalation. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

S-phrase(s):

53-45-60-61

Avoid exposure - obtain special instructions before use. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). This material and its container must be disposed of as hazardous waste. Avoid release to the environment. Refer to special instructions/ Safety data sheets.

EC-No.

231-906-6

EC Label

Reduced labelling (≤125 ml)

Symbol(s):

T+

Very toxic

N

Dangerous for the environment

O

Oxidising

R-phrase(s): 45-46-60-61-21-25-26-

May cause cancer. May cause heritable genetic damage. May impair

 

34-42/43-48/23

fertility. May cause harm to the unborn child. Also harmful in contact with skin. Also toxic if swallowed. Also very toxic by inhalation. Causes burns. May cause sensitization by inhalation and skin contact. Also toxic: danger of serious damage to health by prolonged exposure through inhalation.

S-phrase(s):

53-45

Avoid exposure - obtain special instructions before use. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

National legislation Storage class VCI:

5.1 B Oxidizing agents (TRG 515 Group 2+3)

Major Accident Hazard

96/82/EC

Update: 2003

Legislation:

Very toxic

1

Quantity 1: 5 t Quantity 2: 20 t

Safety Data Sheet according to Regulation (EC) No. 1907/2006

Catalogue No.:

104864

Product name:

Potassium dichromate for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Other regulations:

96/82/EC

Update: 2003

Oxidising

3

Quantity 1: 50 t Quantity 2: 200 t

96/82/EC

Update: 2003

Dangerous for the environment

9a

Quantity 1: 100 t Quantity 2: 200 t

Take note of Dir 94/33/EC on the protection of young people at work. Take note of Dir 92/85/EEC on the safety and health at work of pregnant workers.

16. Other information

Full text of R-phrases referred to under sections 2 and 3

R 8

Contact with combustible material may cause fire.

R21

Harmful in contact with skin.

R25

Toxic if swallowed.

R26

Very toxic by inhalation.

R34

Causes burns.

R42/43

May cause sensitization by inhalation and skin contact.

R45

May cause cancer.

R46

May cause heritable genetic damage.

R48/23

Toxic: danger of serious damage to health by prolonged exposure

R50/53

through inhalation. Very toxic to aquatic organisms, may cause long-term adverse

R60

effects in the aquatic environment. May impair fertility.

R61

May cause harm to the unborn child.

Regional representation:

This information is given on the authorised Safety Data Sheet for your country.

The information contained herein is based on the present state of our knowledge. It characterizes the product with regard to the appropriate safety precautions. It does not represent a guarantee of the properties of the product.