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Battisputali, Kathmandu
Aashish Pandey| 1
1. Preface
It is great pleasure for me that our teacher has provided me this
opportunity to make this paper. I am very much grateful to college and
our biology teacher for providing me this opportunity.
I have prepared this assignment as per my best, but this is not the result of
my sole efforts. This is a moment of great pleasure for me to extend my
sincere gratitude to those people who have contributed me in different
ways to the successful completion of this work.
I specially extend my highest sense of gratitude to the respected CEO
Ramesh Kumar Silwal sir. Likewise, I acknowledge my profound
gratitude to the respected principal, vice principal and all of the teachers
staffs of the Goldengate International College.
I acknowledge my profound gratitude to my friends Nabin Belbase and
Suman Bhandari for their efforts in making this paper. Their contribution
has helped to improve the quality of this document.
I am also grateful to Mr. Ashok KC from St. Xavier's College, Maitighar
for his supports. I am also thankful to Wikipedia and other sites for
providing the knowledge about the content matter.
Finally and importantly, I would like to express my deep gratitude
towards my parents for making this document more comprehensive and
fruitful.
Aashish Pandey| 2
2. Introduction
Nutrition in Latin refers to Gr. nutrine which means to nourish.
Nutrition, nourishment, or aliment, is the supply of materials - food
- required by organisms and cells to stay alive. Every living
organisms require food to produce energy, growth, In science and
human medicine, nutrition is the science or practice of consuming
and utilizing foods.
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4. Food
Food can be said as very essential component for every living
organism hat is taken up by organisms as the source of energy.
Food is not only the source of energy to do work but it also helps in
growth, repair and development of tissue and also provides
resistances to diseases.
On the basis of function of food, they are further classified into 3
categories and are:
4.1 Energy Producers
Energy producers are also called the food for source of energy.
Fats and lipids fall under this category. These food also help in
maintaining homeostasis.
4.3 Regulators
These include some minerals and vitamins that regulate and co
ordinate the body functions.
On the basis of structure, food of animals are grouped under six
components:
4.4 Carbohydrates
A carbohydrate is a biological molecule consisting
of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a
hydrogen–oxygen atom ratio of 2:1 (as in water); in other words,
with the empirical formula Cm(H2O)n. An adult person requires
about 500gm of carbohydrate daily. Maximum of the carbohydrate
we consume seems to be taken from plant polysaccharide, starch
(two-third portion) and remaining from disaccharide, sucrose and
lactose.
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Fig 1.2 Foods containing carbohydrate (Source: Web)
Sources: Rice, wheat, maize, barley, sugarcane, potato, fruits,
milk, etc.
Carbohydrates are further classified into 3 groups:
i. Monosaccharides: Monosaccharides [Greek monos =
single; sacchar = sugar ]or simple sugars consist of one sugar
unit that cannot be further broken down into simpler sugars.
Examples of monosaccharides in foods are glucose,
fructose and galactose. These are simple carbohydrates
involved in energy production cycles and other functions.
ii. Oligosaccharides: Oligosaccharides [Greek oligo = few
sacchar = sugar] are carbohydrates composed of 3 to
9 monosaccharides. Eg. Maltose, Lactose, etc. They have
some special function by being included in most cell
membranes or plasma membranes. For example by being
part of plasma membranes of Red blood cells (i.e.
erythrocytes) they help in damage of erythrocytes by liver
by indication of their time for damage.
iii. Polysaccharides: Polysaccharides [Greek poly = many;
sacchar = sugar] are complex carbohydrates, composed of
10 to up to several thousand monosaccharidess arranged in
chains. The most common monosaccharides that appear as
parts of polysaccharides are glucose, fructose,
galactose and mannose. Thus function of carbohydrates is
diverse and of vital physiological importance in the body.
Though they are very vital, their imbalance can be trouble
some in some disorder like diabetes etc.
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Functions:
1. Provide instant energy to the body: This appears to be the
primary function of carbohydrates in the body.
Carbohydrates which we consume as food in the form of
starch (ex: potato, bread), sucrose (ex: sugar, fruits)etc. get
digested in the body to release glucose. This glucose after
being absorbed into blood reaches all the body tissues and
cell.
There it gets metabolized to release energy in the from of
ATP in the presence of oxygen inside
the mitochondria. Thus energy is produced in the body due
to breakdown of carbohydrates and it is the prime function
of carbohydrates.
2. Reserve food for the body emergency: The excess glucose
in the body is converted to glycogen due to the stimulation
by the hormone insulin. Glucose in blood is converted into
glycogen and stored in the liver for future needs like
starvation. Some of the glycogen is also reserved in muscles.
In times of starvation, this glycogen converts back to
glucose and provides energy.
3. Carbohydrates form other bio molecules: Carbohydrates
in excess are converted into other bio-molecules of
physiological importance like fats, by fatty acid synthesis
reaction in the cell for storage in the body and use in times
of starvation.
4. Detoxification of the body by metabolism: Many drugs,
toxic wastes in the body are metabolized for
easy excretion in the body.
Some of these are water insoluble and hence they are
difficult to be expelled in urine. Body converts them into
glucouronyl conjugates using the glucouronyl moiety
derived from carbohydrates.
A carbohydrate moiety like glucose combines with uronic
acid to form glucouronate. These conjugates of insoluble
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substances with glucouronyls are more water-soluble
and easily excreted from the body. Thus detoxification of
physiological importance is carried out to some extent with
carbohydrate derivatives.
5. As reaction intermediates or accessories: Carbohydrates
participate as reaction intermediates in some vital reactions.
This function of carbohydrates is seen extensively in various
cellular reaction. For example, Vitamin B2 i.e Riboflavin
has ribose sugar (4 carbon) a type of carbohydrate in its
chemical structure and involved in vital reactions at cellular
level. As such carbohydrates are constituents of
many hormones, vitamins, enzymes etc.
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molecules and aid in transfer of oxygen from lungs to the
different tissues.
10. Aid in gut motility: Carbohydrates form fibrous material.
When carbohydrates are digested, this material absorbs
water in the guts, swells and increases the load. This load is
useful to increase intestinal motility and expulsion of waste
(feces). Thus carbohydrates help clear gut and prevent
constipation.
4.5 Proteins
Proteins are essential nutrients for the human body. They are
one of the building blocks of body tissue, and can also serve as a fuel
source. Proteins are polymer chains made of amino acids linked
together by peptide bonds. During human digestion, proteins are
broken down in the stomach to smaller polypeptide
chains via hydrochloric acid and protease actions. This is crucial for
the absorption of the essential amino acids that cannot
be biosynthesized by the body. Proteins are compounds of C, H, O
and N, even some proteins contain S, P and Fe in some amounts. An
adult requires about 50gm of proteins per day.
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On the basis of chemical nature, protein are of three types:
i. Simple Proteins: These proteins are made up of only
amino acids that are interlinked by peptide chains.
Common examples are keratin, chondrin of cartilage,
ossein of bones and myosin of muscles, etc.
ii. Conjugated Proteins: These protein contain non-
proteinous part (called prosthetic group) along with a
proteinaceous part like glycoproteins lipoproteins,
phospoproteins, nucleoproteins, etc.
iii. Derived Proteins: These proteins are obtained by partial
hydrolysis of simple proteins. Eg. Peptones, proteious,
etc.
Functions:
1. Repair and maintenance
Protein is termed the building block of the body. It is called
this because protein is vital in the maintenance of body tissue,
including development and repair. Hair, skin, eyes, muscles
and organs are all made from protein. This is why children
need more protein per pound of body weight than adults; they
are growing and developing new protein tissue.
2. Energy
Protein is a major source of energy. If you consume more
protein than you need for body tissue maintenance and other
necessary functions, your body will use it for energy. If it is
not needed due to sufficient intake of other energy sources
such as carbohydrates, the protein will be used to create fat
and becomes part of fat cells.
3. Hormones
Protein is involved in the creation of some hormones. These
substances help control body functions that involve the
interaction of several organs. Insulin, a small protein, is an
example of a hormone that regulates blood sugar. It involves
the interaction of organs such as the pancreas and the liver.
Secretin, is another example of a protein hormone. This
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substance assists in the digestive process by stimulating the
pancreas and the intestine to create necessary digestive
juices.
4. Ezymes
Enzymes are proteins that increase the rate of chemical
reactions in the body. In fact, most of the necessary chemical
reactions in the body would not efficiently proceed without
enzymes. For example, one type of enzyme functions as an
aid in digesting large protein, carbohydrate and fat molecules
into smaller molecules, while another assists the creation of
DNA.
5. Transportation and storage of molecules
Protein is a major element in transportation of certain
molecules. For example, hemoglobin is a protein that
transports oxygen throughout the body. Protein is also
sometimes used to store certain molecules. Ferritin is an
example of a protein that combines with iron for storage in
the liver.
6. Antibodies
Protein forms antibodies that help prevent infection, illness
and disease. These proteins identify and assist in destroying
antigens such as bacteria and viruses. They often work in
conjunction with the other immune system cells. For
example, these antibodies identify and then surround
antigens in order to keep them contained until they can be
destroyed by white blood cells.
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Waxes: They are the esters of long chain fatty
acids and long chain alcohol.
b) Compound Lipids: Compound Lipids consist of fatty
acids, alcohols as well as some other substances like
phosphorous, carbohydrate, etc. Eg, Phospolipids,
glycolipids, etc.
c) Derived lipids: Those lipids that don't contain fatty
acids in their chain are called derived lipids. Eg.
Carotenoids, Cholestrol, etc.
Functions
1. Lipids are storage compounds, triglycerides serve as reserve
energy of the body.
2. Lipids are important component of cell membranes structure
in eukaryotic cells.
3. Lipids regulate membrane permeability.
4. They serve as source for fat soluble vitamins like A, D, E, K.
5. They act electrical insulators to the nerve fibres, where the
myelin sheath contains lipids.
6. Lipids are components of some enzyme systems.
7. Some lipids like prostaglandins and steroid hormones act as
cellular metabolic regulators.
8. Cholesterol is found in cell membranes, blood, and bile of
many organisms.
9. As lipids are small molecules and are insoluble in water, they
act as signalling molecules.
10. Layers of fat in the subcutaneous layer, provides insulation
and protection from cold. Body temperature maintenance is
done by brown fat.
11. Polyunsaturated phospholipids are important constituents of
phospholipids, they provide fluidity and flexibility to the
cell membranes.
12. Lipoproteins that are complexes of lipids and proteins, occur
in blood as plasma lipoprotein, they enable transport of
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lipids in aqueous environment, and their transport
throughout the body.
13. Cholesterol maintains fluidity of membranes by interacting
with lipid complexes.
14. Cholesterol is the precursor of bile acids, Vitamin D and
steroids.
15. Essential fatty acids like linoleic and linolenic acids are
precursors of many different types of ecosanoids including
prostaglandins, thromboxanes. These play a important role
in pain, fever, inflammation and blood clotting.
4.8 Vitamins
Vitamins are substances that our body needs to grow and
develop normally. There are 13 vitamins our body needs. They
also protect us from diseases as well as act much more role in
metabolic activities.
Types Of Vitamins
On the basis of solubility vitamins are classified as two:
i. Fat Soluble Vitamins: The vitamins that are soluble in
organic solvnets as alcohol, glycerol, CCl4 are said to be
fat soluble vitamins. They are Vitamin (A, D, E, K).
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ii. Water Soluble Vitamins: Vitamni B and Vitamin C are
said to be water soluble vitamin. Vitamin B include B1, B2,
B3, B5, B6, B7, B9 and B12.
4.9 Minerals
Minerals are the inorganic substances that make up 4-5 part of
the total body weight. They are the chemicals that regulate the
metabolic activities in our body. Some of them are: Na, K, Ca,
Mg, Cu. etc.
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4.10 Water
Water makes up about three quarters of our body, for good
reason. Water is the body's transportation and sanitation system.
It maintains blood volume, regulates temperature, keeps the
tissues in the eyes and mouth functioning properly, it dissolves
waste products and carries them out of the body, and it delivers
nutrients from food to all the body's tissues. We could live for
weeks without food, but only days without any water.
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Fig. 1.3 Sources Of Water (Source: Web)
Sources: Rivers, springs, lake, ponds, etc.
Functions:
1. Moistens the tissues in the mouth, nose, and eyes. If you've
ever had a dry mouth, chapped lips, and irritated eyes, you
have felt the effects of a lack of water in body tissues.
2. Regulates body temperature: when you get too warm, you
produce sweat that helps your body cool itself through
evaporation. A person suffering from dehydration can't
produce enough sweat to keep himself cool.
3. Lubricates joints: Soft tissues like cartilage hold water to
cushion the movement of fingers, hips, spine, and all the
major joints of your body. When you get dehydrated, these
joints can feel achy.
4. Removes toxins and waste products: Excess salt, too much
alcohol, excessive exposure to smog and tobacco, all these
unhealthy components come into your body and wreak
havoc, but water facilitates the cleanup process and flushes
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out the harmful toxins. Having enough water in your system
helps the liver and kidneys work better to keep your internal
environment clean.
5. Protects the vital organs: Your brain, heart, lungs, digestive
system, every major system in your body relies on water for
cushioning and to maintain the proper balance of electrolytes.
6. Delivers nutrients: Water dissolves cellular food and
oxygen and carries it all over the body through the blood
stream.
7. Prevents constipation: An adequate amount of water keeps
stools soft and easier to move out of the body.
5. Malnutrition
According to WHO, "Malnutrition refers to deficiencies, excesses
or imbalances in a person’s intake of energy and/or nutrients". The
term malnutrition covers 2 broad groups of conditions. One is
‘undernutrition’—which includes stunting (low height for age),
wasting (low weight for height), underweight (low weight for age)
and micronutrient deficiencies or insufficiencies (a lack of important
vitamins and minerals). The other is overweight, obesity and diet-
related noncommunicable diseases (such as heart disease, stroke,
diabetes and cancer).
5.1 Disorders due to under nutrition
Due to deficiency in protein in the food, under nutrition is
caused. This a common problem in under developed countries.
Undernutrition denotes insufficient intake of energy and
nutrients to meet an individual's needs to maintain good health.
Two main disorders Kwashiorkor and Marasmus are said to be
caused due to under nutrition.
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i. Kwashiorkor: Kwashiorkor, also known as “edematous
malnutrition” because of its association with edema (fluid
retention), is a nutritional disorder most often seen in
regions experiencing famine. It is a form
of malnutrition caused by a lack of protein in the diet.
People who have kwashiorkor typically have an extremely
emaciated appearance in all body parts except their ankles,
feet, and belly, which swell with fluid.
Symptoms:
change in skin and hair color (to a rust color) and
texture
fatigue
diarrhea
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loss of muscle mass
failure to grow or gain weight
edema (swelling) of the ankles, feet, and belly
damaged immune system, which can lead to more
frequent and severe infections
irritability
flaky rash
shock
Control Methods:
To prevent kwashiorkor, make sure the diet has enough
carbohydrates, fat (at least 10 percent of total calories),
and protein (12 percent of total calories).
ii. Marasmus:
Marasmus is a form of severe malnutrition. It can occur in
anyone who has severe malnutrition, but it usually occurs
in children. It typically occurs in developing countries.
Marasmus can be life-threatening, but one can get
treatment for it.
Causes:
Nutrient deficiency is the main cause of marasmus. It
occurs in children that don’t ingest enough protein,
calories, carbohydrates, and other important nutrients.
This is usually due to poverty and a scarcity of food.
There are several types of malnutrition. A malnourished
child may have something other than marasmus. Among
the more common types of malnutrition are serious
deficiencies in:
iron
iodine
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zinc
vitamin A
Symptoms:
The main symptom of marasmus is being underweight.
Children with this condition have lost a lot of muscle
mass and subcutaneous fat. Subcutaneous fat is the
layer of fat just under the skin. Dry skin and brittle hair
are also symptoms of marasmus.
In children with marasmus, the following can also
occur:
chronic diarrhoea
respiratory infections
intellectual disability
stunted growth
Control Methods:
The best way to prevent marasmus is to have a well-
balanced diet. Foods rich in protein like skimmed milk,
fish, eggs, and nuts are important for energy and growth.
Vegetables and fruits are important for providing other
nutrients and minerals and for preventing malnutrition
in general.
Ensuring that complications like dehydration
and diarrhea don't reoccur for those who have been
malnourished before or affected by marasmus are very
important.
Good sanitation and hygiene also play a big role in
spreading disease for people in developing countries.
Poor sanitation and hygiene can lead to infections that
may take a toll on someone who is already close to
malnutrition.
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Cooking foods at high heat to destroy bacteria can help,
as can freezing food and reheating it before eating.
Boiling water before drinking, cooking, or bathing in
areas where clean water is difficult to access is
important to prevent spreading waterborne diseases.
New mothers can also help prevent malnourishment in
their newborns by breastfeeding as much as possible.
Symptoms:
Incresed level of cholestrol in body.
Increased heart beat and blood pressure.
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Coronary thrombosis may lead into heart attack.
Prevention Methods:
Regular exercises
Balanced diet
ii. Obesity:
Symptoms:
breathing disorders (e.g., sleep apnea, chronic
obstructive pulmonary disease)
certain types of cancers (e.g., prostate and bowel
cancer in men, breast and uterine cancer in women)
coronary artery (heart) disease
depression
diabetes
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gallbladder or liver disease
gastroesophageal reflux disease (GERD)
high blood pressure
high cholesterol
joint disease (e.g., osteoarthritis)
stroke
Control Methods:
Mental relax
Regular exercise
Proper drinking of water
Balanced diet
Balanced diet:
The food that contains all the required nutrients for our body in
proper and in adequate amount.