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*Correspondence to: R. Basson. UBC Departments of Psychiatry and Obstetrics & Gynecology, B.C. Centre for Sexual
Medicine, VHHSC. Echelon 5,855 West 12th Avenue, Vancouver, BC, V5Z 1M9, Canada. Email: sexmedQinterchange.ubc.ca
assumptions about women’s sexual response. tions of dysfunction follow. The overall
Over the course of one year, the committee objective of this committee was to document
formulated modifications and elaborations of the inaccuracies and limitations of the
existing definitions of women’s sexual dys- existing definitions, and to encourage the
function. Many subsequent revisions were researching of further data to support, refute
made, facilitated by three meetings, and or modify these revisions and to test their
ongoing electronic communication especially usefulness and validity in the clinical setting.
once the new formulations were piloted by
some of the authors. It is recognized that EXISTING BELIEFS ABOUT WOMEN‘S
the ultimate validity and reliability of the SEXUAL RESPONSE
proposed modifications must be tested
Organic dysfunction can be meaningfully
formally in both clinical and research settings
separated from psychogenic dysfunction
over the coming months and years.
The traditional models of women’s sexual Both the DSM-IV-TR and the ICDlO definitions
J Psychosom Obstet Gynaecol Downloaded from informahealthcare.com by University of British Columbia on 05/18/10
- I
Positive 1 or more reasons
influence on for sexual activity:
motivat/l not currently aware
of sexual desire
Willingness t o
find/be receptive
I1 Emotional &
physical
satisfaction
I1
Awareness of Sexual stimuli
I
A\ =
sexual desire - with appropriate
triggers unkown
J Psychosom Obstet Gynaecol Downloaded from informahealthcare.com by University of British Columbia on 05/18/10
psychological
Figure 1 Women's sexual response cycle: sexual arousal may precede sexual desire. Reproduced with
permission from the American College o f Obstetricians and gynecologist^^^
for the partner or a need to confirm one's sexual arousal, desire is not triggered and
desirability.In fact, some reasons for engaging further sexual exchange may be avoided.
For personal use only.
in sex are not positive but may be based on a Alternatively, sex may continue but be
wish to avert a negative outcome, for example, experienced without pleasure and often
to avoid a partner's petulance or anger. without further subjective arousal.
Research evidence from nationally repre A different model of women's sexual
sentative community samples of adult response has been described, showing that
women confirms the finding of infrequent arousal and desire coexist and reinforce each
spontaneous sexual thinking in the majority other (Figure 1).Comorbidity of arousal and
of sexually healthy women in longer-term desire may be the rule rather than t h e
relati~nships'~-~~'. exception.
Fantasies, a marker of sexual desire in
many systems including DSM-IV-TR, may, in
Women's sexual arousal is identified primarily
fact, serve as a deliberate means of creating
by genital vasocongestion, vaginal lubrication
arousal and reinforcing desire. Data suggest
andawareness of genital throbbingand tingling
women fantasize as a means to better focus
on their sexual feelings and to avoid distrac- In fact, women's sexual arousal includes
tions during sexual activityz'. various components including sexual excite
ment - a sense of being sexually awakened.
There is heightened awareness of the external
Sexual desire necessarily precedes sexual stimuli that are causing the sexual
sexual arousal excitement.
As discussed in a previous paper, it is often There is also variable awareness of
the case that arousal precedes desireZ2.Data physiological changes in the body including
are emerging on the wide variety of motives vasocongestion of the genitalia and breasts.
women may have for agreeing to, or insti- Genital vasocongestion may be rather mini-
gating, sexual a ~ t i v i t y ~The
~ -willingness
~~. to mally and imprecisely directly recognized by
be sexual, leads to both a deliberate attempt the woman. For many, but not all, healthy
to become aware of subjective and physical women, direct awareness (tingling, throb-
feelings of arousal as well as greater engage- bing, fullness)is not proportional to increased
ment in the sexual situation. These processes vaginal engorgement as measured by vaginal
then facilitate sexual desire and a wish to p h o t o p l e t h y ~ m o g r a p h y ~
However,
~. i t is
continue the sexual acts. On the other hand, awareness of genital arousal that is the focus
without the reinforcement of increasing of the definitions of DSM-IV-TR and ICDIO.
women complaining of poor arousal, their little clinical but some epidemiological
degree of anxiety in response to an erotic relevanceto.
stimulus actually correlates with psycho- In light of all of the above points, we are
physiological measures of genital conges- proposing the following modifications and
tion 18.35 36
elaborations of existing definitions of
Brain imaging in sexually aroused women women's dysfunction. The dysfunctions rarely
is i n keeping with previous psychophysi- occur alone and influence and compound
ological findings that their subjective arousal each other as illustrated in Figure 2.
does not necessarily correlate with genital
response. In the imaging studies, there is SEXUAL DISORDERS
uptake in areas corresponding to cognitions,
Women's sexual interest/desire disorder
emotions, motivations and in areas organ-
izing and perceiving autonomic reflexes. Of 'Absent or diminished feelings of sexual
note, there is minimal correlation between interest or desire, absent sexual thoughts or
uptake in areas organizing ANS reflexes fantasies and a lack of responsive desire.
and the women's subjective experience of Motivations (here defined as reasons/incen-
arousaP. tives), for attempting to become sexually
aroused are scarce or absent. The lack of
interest is considered to be beyond a normative
Women's sexual response is essentially stable lessening with life cycle and relationship
and invariant across time and circumstance duration'.
It is becoming increasingly apparent as The word 'interest' is preferred given the
Kinseyj9 noted in 1953. that women's sexual aforementioned relative infrequency of desire
response is discontinuous across the repro- being the reasonlincentive for engaging in
ductive and sexual life cycle. It is strongly sexual activity. However, for practical pur-
influenced by the context of any actual or poses of literature review, the combination
potential sexual interaction. It may be is chosen. The definition reflects the data
affected by normal reproductive events which show a paucity of sexual thoughts and
including menstrual cycle, pregnancy, fantasies may be within the broad normative
postpartum and menopause. It may also range. The additional lack of responsive desire
be affected by minor and major medical is essential to the diagnosis of dysfunction.
Vaginismic
difficulties
Figure 2 Schematic for understanding the complexity of women’s sexual dysfunction. Components of
women‘s sexuality overlap significantly. The dark gray area in the middle of the schematic represents the
co-occurrence of all types of dysfunction and is not uncommon in clinical practice.
For personal use only.
her relationship and environment. She is are using the word ‘dysfunction’ to mean
reporting that dysfunction is present - how- simply lack of healthy/expected/normal
ever, factors other than the woman’s own responselinterest. The use of this word does
sexuality need to be highlighted. Agreeing not necessarily imply any pathology within
with Schover e t aL5’who described a multi- the woman.
axial problem-oriented diagnostic system in The phrase ‘ongoing difficulties with’,
1982, we again strongly recommend the might be more accurate than ‘dysfunction’,
inclusion of descriptors within the diagnosis but cumbersome and not in keeping with
as these have such important therapeutic psychological and medical terminology.
implications. The descriptors may or may not Given the documented co-morbidity, often
eventually prove to be etiologically importantseveral diagnoses will apply. Thus, although
- there is often considerable uncertainty. Thethe definitions of women’s sexual dys-
following descriptors appear to be most functions have become somewhat longer and
salient: more complex, we believe that this reflects
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11. Hartmann U, Heiser K, Riiffer-Hesse C. et al. 30.Laan E, Everaerd W, van der Velde J , et al.
Female sexual desire disorders: Subtypes, Determinants of subjective experience of
classification, personality factors, a new sexual arousal in women: Feedback from
direction for treatment. WorldJ Urol 2002;20: genital arousal and erotic stimulus content.
79-88 Psychophysiology 1995;32 :444-51
12.Basson R, Mclnnes R, Smith MD, rt al. Efficacy 31. Everaerd W, Laan E, Both S, et al. Female
and safety of sildenafil citrate in women with sexuality. In Szuchman LT, Muscarella F, eds.
sexual dysfunction associated with female Psychological perspectives of human sexuality. New
sexual arousal. Gend Based Med 2002;11:367-77 York: John Wiley & Sons Inc., 2000
13.Cyranowski JM. Andersen BL. Schemas, 32. Meston CM. Heiman JR. Ephedrine-activated
sexuality. romantic attachment.] Personality physiological sexual arousal in women. Arch
Sor Psycho1 1998:74:13@-79 Gen Psychiatry 1998;55:652-6
14. Derogatis LR, Schmidt CW, Fagan PJ, et al. 33. Meston CM. Gorzalka BB. The effects of immedi-
Subtypes of anorgasniia via mathematical ate, delayed and residual sympathetic activation
taxonomy. Psychosomatics 1989:30:166-73 on physiological and subjective sexual arousal
15. Segraves KB, Segraves RT. Hypoactive sexual in women. Behav Res Ther 1996;34:143-8
J Psychosom Obstet Gynaecol Downloaded from informahealthcare.com by University of British Columbia on 05/18/10
desire disorder: Prevalence and comorbidity 34.Brotto L, Gorzalka B. Genital and subjective
in 906 subjects.] Sex Marital Ther 1991:17:55-8 sexual arousal in postmenopausal women:
16.Rosen RT. Taylor JF. Leiblum SR. Prevalence of Influence of laboratory induced hyperventila-
sexual dysfknction in women: Results of a tion.] Sex Mar R e r 2002:283:39-53
survey study of 329 women in an outpatient 35.MorokoffPJ. Heiman JR. Effects oferotic stimuli
gynecological c1inic.J Sex Marital Ther 199339: on sexually functional and dysfunctional
171-88 women: Multiple measures before and after
17. Meston CM. Validation of the female sexual sex therapy. Behav Res Ther 1980:18:127-37
function index (FSFI)in women with female 36.Laan E, van Driel E, van Lunsen RHW. Seksuele
orgasmic disorder and in women with reakties van vrouwen met een seksuele
hypoactive sexual desire dis0rder.J Sex Marital opwindingsstoornis op visuele seksuele
Ther 2003;29:39-46 stimuli [Sexual responses of women with
18.Trudel G, Ravart M. Matte B. The use of the sexual arousal disorder to visual sexual
multi axis diagnostic system for sexual stimuli]. Tijdschrift voor Seksuologie 2003;27:1-13
dysfunctions in the assessment of hypoactive 37. Wouda JC, Hartman PH, Bakker R, et al.
sexual desire. J Sex Marital Ther 1993;19:123-30 Vaginal plethysmography in women with
For personal use only.
19.Bancroft J, Loftus J, Long JS. Distress about sex: dyspareunia.J Sex Res 1998;35:141-7
A national survey of women in heterosexual 38.Karama S,Lecours AR, Leroux JM. et al. Areas
relationships. Arch Sex Behav 2003:32:193-204 of brain activation in males and females
20.Cawood HH, Bancroft J. Steroid hormones, during viewing of erotic film excerpts. Hum
menopause, sexually and well being of women. Brain Mapp 2002;16:1-13
Psychophysiol Med 1996:26:925-36 39.Kinsey A. Sexual Behavior i n the Human Female.
21.Garde K, Lunde I. Female sexual behaviour: Bloomington: Indiana University Press, 1953
The study in a random sample of 4@year+ld 40.Dennerstein L, Lehert P. Burger H, et al. Factors
women. Maturitas 1980;2:225-40 affecting sexual functioning of women in the
22.Basson R. The female sexual response: A midlife years. Climacteric 1999;2:254-62
different Model.J Sex Marital Ther 2000;26: 41. Hill CA. Gender, relationship stage, and
51-65 sexual behaviour: The importance of partner
23.Lunde I, Larson GK. Fog E, et al. Sexual desire, emotional investment within specific
orgasm, and sexual fantasies: A study of 625 situati0ns.J Sex Res 2002;39:228-40
Danish women born in 1910. 1936 and 1958. 42. Fugl-Meyer AR, Sjogren Fugl-Meyer K. Sexual
J Sex Educ Ther 1991:17:111-15 disabilities, problems and satisfaction in 18 to
24.Hill CA. Preston LK. Individual differences in 74-year-old Swedes. ScandJ Sexology 1999;2:
the experience of sexual motivation: Theory 79-105
and measurement of dispositional sexual 43. Sprecher S. Sexual satisfaction in premarital
motives. J Sex Res 1996;33:27-45 relationships: Associations with satisfaction,
25.Galyer KT, Conaglen HM. Hare A. et al. The love, commitment, and stability.] Sex Res
effect of gynecological surgery on sexual 2002;39:190-6
desire. J Sex Marital Ther 1999:25:81-8 44.Kontula 0, Haavio-Mannila E. Sexual pleasures.
26.Weijmar Schultz WCM, van de Wiel HBM. Enhancement ofsex life in Finland. Aldershot, UK:
Hahn DEE. Psychosexual functioning after Dartmouth Pub. Co., 1995:1971-92
treatment for gynecological cancer and 45. Sipski M, Rosen R. Alexander CJ, et al. Sildenafil
integrated model. review of determinant effects on sexual and cardiovascular responses
factors and clinical guidelines. IntJ Gvnerol in women with spinal cord injury. Urology
Cancer 1992;2:281-90 2000:55:812-15
27. Regan P. Berscheid E. Belief about the states, 46.Wilbur JE, Miller AM, Montgomery A, et al.
goals and objects of sexual desire.] Sex Marital Sociodemographic characteristics, biological
Ther 1996;22:110-20 factors and symptom reporting in midlife
28. Klusmann D. Sexual motivation and the women. Menopause 1998;5:43-51
duration of partnership. Arch Sex Behav 2002; 47. Barentsen R, van de Weijer PH, Schram JH.
31:275-87 Continuous low dose estradiol released from a
29.Basson R. Female sexual response: the role of vaginal ring versus estriol vaginal cream for
drugs in the management of sexual urogenital atrophy. EurJ Obstet Gynecol1997;71:
dysfunction. Obstet Gynecol 2001;98:350-3 73-80