6.

Generic Name: Misoprostol Brand Name: Cytotec

Classification: prostaglandin

Therapeutic actions: a synthetic prostaglandin E1 analogue: inhibits gastric

Acid secretion and increases bicarbonate and mucus

production, protecting the lining of the stomach

Indications : w/ mifepristone as an abortifacient ; cervical ripening and labor

Induction
Contraindications: w/ history of allergy to prostaglandins ; use cautiously in
the elderly and with renal impairement
Adverse effects: GI- nausea, diarrhea, abdominal pain
GU- miscarriage, excessive bleeding
Nursing Considerations: assess history of allergy to this drug, take this drug
4x a day, with meals and before bedtime , report
severe diarrhea and spotting

7. Generic Name: Carboprost tromethamine Brand Name: Hemabate

Classification: Abortafacient, prostaglandin
Therapeutic Actions: stimulates the myometrium of the gravid uterus to
contract in a manner that is similar to the contractions
of the uterus during labor, thus evacuating the contents
of the gravid uterus
Indications: termination of pregnancy 13-20 k from the 1st day of the last
menstrual period, postpartum hemorrhage due to uterine atony
Contraindications: w/ allergy to prostaglandin preparations, use cautiously
with history of asthma
Adverse Effects: CNS- headache, flushing, anxiety
CV- hypotension, arrhythmias
GI- vomiting, nausea
GU- endometritis
Nursing Considerations: allergy to prostaglandin preparations, refrigerate
unopened vials, administer by deep IM injections

8. Generic Name: Nalbuphine Hydrochloride Brand Name: Nubain

Classification: opioid antagonist-agonist analgesic
Therapeutic Actions: acts as an agonist at specific opioid receptors in the
CNS to produce analgesia and sedation but also acts to
cause hallucinations and is an antagonist at mu
 receptors
Indications: relief to moderate to severe pain, preoperative analgesia
Contraindications: w/ hypersensitivity to nalbuphine, use cautiously w/
patients w/ history of narcotic abuse
Adverse Effects: CNS- sedation, seating, clamminess
CV- hypotesion, hypertension
GI- nausea, vomiting
Nursing considerations: hypersensitivity to nalbuphine, reassure patient about
addiction liability

9. Generic Name: Terbutaline Sulfate Brand Name: Brethine

Classification: antiasthmatic, tocolytic, bronchodilator
Therapeutic Actions: in low doses, acts relatively at beta2- adrenergic
receptors to cause bronchodilation and relax the
pregnant uterus
Indications: prophylaxis and treatment of bronchial asthma and reversible
Bronchospasm
Contraindications: hypersensitivity to terbutaline, use cautiously w/ diabetes
and CAD
Adverse Effects: CNS- restlessness, anxiety, fear
CV- cardiac arrhythmias, palpitations, angina pain
GI- nausea, vomiting,
Nursing Considerations: drug tolerance can occur w/ prolonged use, don’t
exceed recommended dosage

10. Generic Name: Lidocaine Hydrochloride Brand Name: Dilocaine

Classification: antiarrythmitic , anesthesia
Therapeutic Actions: bocks the generation and conduction of action potentials
in sensory nerves by reducing sodium permeability
Indications: management of acute ventricular arrhythmias during cardiac
surgery, infiltration anesthesia
Contraindications: w/ allergy to lidocaine or amid type anesthesia, use
cautiously w/ hepatic or renal impairement
Adverse Effects: CNS- dizziness, fatigue, drowsiness
CV- cardiac arrest, cardiac arrhythmias
GI- nausea, vomiting
Nursing Considerations: check drug concentration carefully, keep life-suport
and vasopressors readily available, monitor for
malignant hyperthermia