MGG 7010 Molecular Biology and Genetics – Fall 2018

Time: 12:30 – 2:10 p.m.

Place: 3125 Scott Hall
Texts: Molecular Cell Biology, 8th ed., Lodish et al. (W. H. Freeman). Additional readings as assigned.

Date Topic Lecturer Chapter

8/29 Introduction to course; Protein Structure and Dr. Grossman 3
Function
8/31 Introduction to Nucleic Acids and Molecular Genetics Dr. Grossman 5.1; 6
9/5 Genetic Analysis and Techniques Dr. Grossman 6
9/7 Genes and Chromosomes Dr. Hüttemann 8; 12.2
9/12 Genes and Chromosomes Dr. Hüttemann 8; 12.2
9/14 Genes and Chromosomes Dr. Hüttemann 8; 12.2
9/19 ✩✩✩ EXAM 1 ✩✩✩ (THROUGH 9/14)
9/21 DNA Replication, Repair and Recombination Dr. Hüttemann 5.5; 5.6; 19.4; 24.4
9/26 DNA Replication, Repair and Recombination Dr. Hüttemann 5.5; 5.6; 19.4; 24.4
9/28 DNA Replication, Repair and Recombination Dr. Hüttemann 5.5; 5.6; 19.4; 24.4
10/3 Cell Biology of Mitosis and Meiosis Dr. Finley 18.1-18.6; 19
10/5 Cell Cycle Regulation – Mitosis Dr. Finley 19
10/10 Cell Cycle Regulation - Proliferation Dr. Finley 19
10/12 Neurobiology Dr. Gow 22
10/17 ✩✩✩ EXAM 2 ✩✩✩ (THROUGH 10/10)
10/19 Protein synthesis Dr. DeGracia 5.3-5.4
10/24 Regulation of Protein Synthesis Dr. DeGracia 5; handout
10/26 ER protein processing; unfolded protein response Dr. DeGracia 13 intro, 13.1-13.3
10/31 Genome Stability Dr. Wu 24
11/2 Oncogenes and Tumor Suppressors Dr. Wu 24
11/7 Transcription factors and distal enhancers Dr. Pique-Regi 9
11/9 Gene Expression: Initiation and Regulation of Dr. Lipovich 5.2; 8.1-8.5; 9.2-
Transcription 9.8
11/14 ✩✩✩ EXAM 3 ✩✩✩ (THROUGH 11/7)
11/16 RNA processing and Post-transcriptional Regulation Dr. Lipovich 10.1-10.5
11/21-23 Thanksgiving recess No class
11/28 Functional non-coding RNA; and mini-review of Dr. Lipovich 6.2, 6.3, refresh
11/17, 12/1, and 12/8 lectures to prepare for Exam 4. 9.7 and 10.4
Other readings for 12/8: http://www.nature.com/encode/threads/non-coding-rna-characterization

and papers hyperlinked on the left side of that

webpage.
11/30 Gene Regulation During Development Dr. Li 15, 16, 21, 22
12/5 Gene Regulation During Development Dr. Li 15, 16, 21, 22
12/7 Gene Regulation During Development Dr. Li 15, 16, 21, 22
12/12 ✩✩✩ EXAM 4 ✩✩✩