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Drug Study

Name of Drug Mechanism of Indication Contraindication Side Effects Nursing Responsibility


Action
Generic Name: Action: Therapeutic Pregnancy category CNS: Dizziness, Assessment
Losartan Blocks the outcome: D (2nd/3rd trimester), insomnia,  Assess blood pressure
(low-sar’tan) vasoconstrictor and Decreased blood hypersensitivity anxiety, with position changes,
aldosterone-secreting pressure confusion, pulse rate every 4
Brand Name: effects of angiotensin abnormal hours, rhythm, quality
Cozaar II; selectively blocks Uses: Precautions: dreams,  Monitor electrolytes:
the binding of Hypertension, alone Pregnancy category migraine, potassium, sodium,
Functional class: angiotensin II to the or in combination; C (1st trimester), tremor, vertigo, chloride
Antihypertensive AT1 receptor found in nephropathy in type 2 breastfeeding, headache  Obtain baselines for
tissues diabetes, hypertension children, geriatric renal, liver function
Chemical class: with left ventricular hypersensitivity to CV: angina before therapy begins
Angiotensin II hypertrophy ACE inhibitors, pectoris, 2nd-  Monitor for edema in
receptor (type AT1) hepatic disease, degree AV feet, legs daily
angioedema, renal block, CVA,  Assess for skin turgor,
Pregnancy category: artery stenosis hypotension, MI, dryness of mucous
C (1st trimester) dysrhythmias membranes for
D (2nd/3rd trimester) hydration status
EENT: Blurred
Dosage and routes: vision, burning
Oral: PO 50mg/day eyes, Nursing Diagnosis
alone or 25mg/day conjunctivitis  Fluid volume deficit
when used in
 Noncompliance of
combination with GI: Diarrhea, patient
diuretic, maintenance dyspepsia,
 Knowledge deficit
25-100mg/day anorexia,
constipation, dry
. mouth,
Implementation
flatulence,
 Administer without
gastritis,
regards to meals
vomiting
Patient/family education
Drug Study

GU: Impotence,  Teach patient to avoid


nocturia, urinary sunlight or wear
frequency, sunscreen if in
urinary tract sunlight;
infection, renal photosensitivity may
failure occur
 Advise patient to
HEMA: Anemia comply with dosage
schedule, even if
INTEG: feeling better
Alopecia,  Teach patient to notify
dermatitis, dry prescriber of mouth
skin, flushing, sores, fever, swelling
photosensitivity, of hands or feet,
rash, pruritus, irregular heartbeat,
sweating, chest pain
angioedema  Advise patient that
excessive perspiration,
META: Gout dehydration, vomiting,
diarrhea may lead to
MS: Cramps, fall in blood pressure,
myalgia, pain, consult doctor right
stiffness away
 Inform patient that
RESP: Cough, product may cause
upper respiratory dizziness, fainting,
infection, light-headedness may
congestion, occur
dyspnea,  Caution patient to rise
bronchitis slowly to sitting or
standing position to
minimize orthostatic
hypotension
Drug Study

 Advise patient to use


contraception while
taking product

Evaluation
Positive therapeutic
outcome
 Decrease blood
pressure

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