Name of Drug Classification and Indication and Side Effects or Adverse
(Dosage, Route, Mechanism of Action Contraindication
Frequency, Timing)
Generic Name: Classification: Indication:
Paracetamol Anti-pyretic - Analgesic-antipyretic
inpatients with aspirin
allergy, hemostatic
Brand Name: disturbances, bleeding
Biogesic diatheses, upper GI disease,
gouty arthritis- Arthritis and
rheumatic disorders
Dosage: involving musculoskeletal
137mg Mechanism of Action: pain (but lacks clinically
Reduces fever by acting significant antirheumatic
directly on the and anti-inflammatory
hypothalamic heat- effects)- Common cold,
Route: regulating center to cause flu, other viral and
IV vasodilation and bacterial infections with
sweating, which helps pain and fever- Unlabeled
dissipate heat. use: Prophylactic for children
receiving DPT vaccination to
Frequency: reduce incidence of fever
Q4h and pain
Contraindication:
- Contraindicated with
allergy to acetaminophen.
Timing: -Use cautiously with
PRN for fever impaired hepatic function,
chronic alcoholism,
pregnancy, lactation
Nursing Responsibilities
Reactions
CNS:  In children don’t
Headache exceed five doses
CV: in 24 hours.
Chest pain , dyspnea,  Advise patient
Myocardial damage that drug is only
When doses of 5–8 for short term use
g/day are ingested daily and to consult the
for several weeks or when physician if
doses of 4g/day are giving to children
ingested for 1 yr for longer than 5
GI: Hepatic toxicity days or adults for
and failure, longer than 10
jaundice days.
GU:  Warn patient that
Acute kidney failure, renal high doses or
tubular necrosis unsupervised long
Hematologic: term use can
Methemoglobinemia cause liver
—cyanosis; hemolytic damage.
anemia
— hematuria, anuria;
neutropenia, leucopenia,
pancytopenia,
thrombocytopenia,
hypoglycemia
Hypersensitivity:
Rash, fever