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Biperiden is an anticholinergic drug used to treat Parkinsonian syndrome and extrapyramidal symptoms. It works by competitively blocking acetylcholine receptors in the corpus striatum to restore balance. Common side effects include dry mouth, constipation, blurred vision, dizziness, drowsiness and confusion. Nurses should monitor for side effects, advise patients on safe medication use, and reassess the patient's condition after treatment.
Biperiden is an anticholinergic drug used to treat Parkinsonian syndrome and extrapyramidal symptoms. It works by competitively blocking acetylcholine receptors in the corpus striatum to restore balance. Common side effects include dry mouth, constipation, blurred vision, dizziness, drowsiness and confusion. Nurses should monitor for side effects, advise patients on safe medication use, and reassess the patient's condition after treatment.
Biperiden is an anticholinergic drug used to treat Parkinsonian syndrome and extrapyramidal symptoms. It works by competitively blocking acetylcholine receptors in the corpus striatum to restore balance. Common side effects include dry mouth, constipation, blurred vision, dizziness, drowsiness and confusion. Nurses should monitor for side effects, advise patients on safe medication use, and reassess the patient's condition after treatment.
Brand name: Akineton, Akidin, Apiden Drug Classification: Anticholinergic
DOSAGE, ROUTE, FREQUENCY MECHANISM OF ACTION SIDE EFFECTS and ADVERSE
(prescribed and recommended) INDICATION REACTIONS (by system) Description: Biperiden is an Initially 1mg BID, increased by Parkinsonian anticholinergic agent w/ Urinary retention, dry 2mg/day; PO syndrome marked effect on the CNS mouth, constipation, especially to which is important for its nausea, vomiting, dyspepsia, counteract therapeutic application and blurred vision, mydriasis, dry muscular rigidity has weak peripheral eyes, tachycardia, and tremor; vegetative effects. The arrhythmia, dizziness, extrapyramidal mechanism of action is drowsiness, headache, symptoms considered to relate to hallucinations, memory competitive antagonism of impairment, confusion, acetylcholine at cholinergic insomnia, worsening of receptors in the corpus dyskinesia, generalised striatum, which then restores choreic movements, fever the balance. due to anhidrosis, rash, Pharmacokinetics: flushed skin, dry skin, Absorption: Readily absorbed hypersensitivity reactions. from the GI tract. Bioavailability: Approx 30%. Metabolism: Undergoes extensive first-pass metabolism. Excretion: Elimination half- life: Approx 20 hr.
NURSING RESPONSIBILITIES (at least 10)
CONTRAINDICATION/S Untreated narrow-angle glaucoma, 1. Advice patient to take the medication with meals. mechanical stenoses in the GI tract, 2. Assess for parkinsonism, EPS. paralytic ileus, megacolon, prostatic 3. Assess for mental status. adenoma and diseases that can lead 4. Assess patient response if anticholinergics are given. to perilous tachycardia. 5. Assess for tolerance over long term therapy, dosage may have to be increased or changed. 6. Avoid activities that require alertness, may cause dizziness and blurring of vision. 7. This drug may cause drowsiness, dizziness or blurred vision, if patient is affected, do not let him/her drive or operate machinery. 8. Advice patient not to drink alcoholic beverages to prevent drug- food interaction. 9. Monitor patient’s vital signs. 10. Reassess patient’s condition when the medication is expected to take effect.