Female Genital Tract

Q.1) A woman from Asia has increased levels of bHCG. She recently had a pregnancy and it
was a mole. The structure was hemorrhagic and friable, with no chronionic villi. Which of
the following are key features of her disease?
A. malignant cytotrophoblasts
B. malignant syncitiotrophoblasts
C. cured with chemotherapy
D. extensive metastasis
E. all of the above

Q.2) A woman presents with amenorrhea, vomiting and positive for pregnancy test. Three
to four months later, she has vaginal bleeding with grape like structures present. There are
also fetal parts present. The most likely chromosome for her mole is:
A. 69 XXY
B. 46 XX
C. 46 XY
D. None of the above
E. All of the above

Q.3) All of the following are predisposing factors for pre-eclampsia except?
A. primagravida, over 35 years
B. multiple pregnancies, hydramnios
C. preexisting hypertension
D. hyadatiform mole
E. All are predisposing factors

Q.4) A patient presenting with gestational edema, proteinuria, and hypertension, not before
pregnancy, is diagnosed with ____________.
( 1 word )

Possible correct answers:

 Pre-Eclampsia

Q.5) Patient presents with decreased levels of estrogen and progesterone. She has excessive
bleeding due to breaking down of her endometrium. Her uterus is small compared to her
amenorrhea. The bHCG levels are also low, indicating the death of an embryo. What is the
most likely cause of her pregnancy?
A. PID
B. endometriosis
C. PID or endometriosis
D. None of the above
E. it is a hydatiform mole

Q.6) Absence of a plane of separation between villi and myometrium, with severe post
partum hemorrhage and a hysterectomy, all indicate_____________________.
( 2 words )

Possible correct answers:

 placenta accreta

Q.7) A patient presents with papillomatous warts on her cervix. Blood tests reveal that she
has an STD infection, from HPV. Histology reveals koilocytes (which is not indicative of
malignancy). The mechanism of her lesions occurs by activation of _________________.
A. p53
B. rb gene
C. cyclin E
D. all of the above are activated
E. none of the above
Q.8) Postcoital bleeding is associated with _______________.
( 5 words )

Possible correct answers:

 squamous carcinoma of the cervix

Q.9) Sarcoma botryoides is an embryonal rhabdomyosarcoma seen in less than five years
old kids, which looks like a bunch of grapes hanging in the vagina, and is highly _.
( 1 word )

Possible correct answers:

 malignant.