Endometrial Pathology

Q.1) What is the meaning of endometriosis?

A. Occurrence of endometrial tissue at site other than the lining of uterine cavity
B. cyclical shedding of endometrium, no foothold
C. none of the above
D. all of the above
E. does not matter

Q.2) Postpartum sepsis (puerperal sepsis), ascending gonococcal, and pyometrum

(obstruction of os by neoplasm) as all associated etiologies of _________.
( 1 word )

Possible correct answers: endometritis

Q.3) A woman presents with dysmenorrhea, menorrhagia, and infertility with complications
of tubal pregnancy. She is diagnosed with endometriosis. The possible mechanisms of this
disease include, retrograde movement of blood during menstruation, vascular dissemination
through blood or lymphatics, and metaplasia of celomic epithelium. A key gross feature of
her disease would be ________________.
( 5 words or 2 words )

Possible correct answers:

 chocolate cysts of the ovary
 follicular cysts
 simple cysts

Q.4) A woman, upon taking a biopsy of her endometrial tissue, is said to present with a
premalignant lesion that is in-situ and with atypia. After providing progesterone therapy, the
lesion regressed. Which of the following is the most likely cause of her lesion?
A. increased estrogen levels
B. decreased estrogen levels
C. increased testosterone levels
D. none of the above
E. all of the above
Q.5) A 60 year old woman obese woman, with diabetes and hypertension, presents with
post menopausal bleeding, a biopsy of her tissue is taken and she is diagnosed with cancer
of the endometrium. Grossly you see a polypoind fungating mass in the cavity. What is a key
histological feature of her disease?
A. back to back glands
B. increased cysts in the glands
C. koilocytes
D. all of the above
E. none of the above.

Q.6) A 35 year old woman presents with masses in the endometrium. Gross the cut surface
of the lesion appears as whorled masses. She presents with menorrhagia, metorrhagia, and
acute pain during pregnancy, also known as red degeneration. What are the chances of her
lesion progressing to malignancy?
A. High
B. low
C. very high, because most likely it will lead to leiomyosarcomas
D. all of the above
E. A and C

Q.7) A 70 year old woman presents with post menopausal bleeding. It is known that the
tumor is large, bulky, with hemorrhage, and necrosis. The tumor is not associated with
leiomyosarcoma. What is the prognosis of her tumor?
A. good
B. poor
C. unsure
D. all of the above
E. none of the above