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WOVE style

To Achieve Excellent Results!


The Treatment of The Beauty Clinic for Your Salon

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What is Electroporation?
●Electroporation: Needle-free, Pain-free Anti-Aging Treatment

The origin of the basic methodology of electroporation


was the electrophysiological technique, first developed
in the late 1970s. This technique treated nerve and
cardiac muscle cells.
The first electroporation was a medical device
designed to deliver medicine painlessly into the body.
Peter Agre, an American physician, professor, and
molecular biologist, was awarded the 2003 Nobel Prize
in chemistry for his discovery of aquaporin.

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What is Electroporation?
 Electroporation is in beauty treatment to perform mesotherapy without
needles. note: Mesotherapy treatment is a non-surgical cosmetic solution
by which effective ingredients and/or medicines are injected into the skin for
facial or slimming treatment.

 Electroporation is a mechanical transfection method that uses an electrical


pulse instead of a needle. Electroporation produces temporary pores in cell
membranes through which ingredients or essences can pass into cells in
order to perform treatment such as a facial, slimming, or breasts
enhancement.

 Unlike iontophoresis and supersonic wave methods, electroporation delivers


even high-molecular ingredients into skin.

※Electroporation can inject ingredients approximately 20 to 60 times deeper


than iontophoresis method does.

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What is Electroporation?
【Theory】The theory of the electroporation delivery system.
 Directly acts on the skin, instantly enhances skin tissue penetration. Under the function of
electroshock, holes will be formed in the lipid mobilization of cells; at the same time,
hydrophile molecules, which have not been absorbed originally, can penetrate into cells
inner. (The 2003 Novel Prize in Chemistry for discovery of aquaporin)

 The cell is in an opened condition for a few seconds to minutes, and the hole will close
naturally. The duration of the cell’s opened state depends on the pulse length.

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Theory of the Iontophoresis
◆With the iontophoresis
Iontophoresis is based on the general principle that like
charges repel each other and unlike charges attract
each other. This external energy source can be used to
increase the rate or penetration of beauty ingredients
through the membrane.
◆Disadvantages of Iontophoresis
 The substance to be driven into the tissues needs to be
ionic in nature.

 Minor reactions such as itching, erythema and general


irritations are common. Electrolysis of moisture inside and
outside of the skin occurs when iontophoresis treatment
is performed.
For instance, using a negative electric current decomposes the water in the skin and then,
the skin becomes strongly alkalinity and could suffer itching or irritations.
Pain and irritation of the skin may occur through the pH change.

 Iontophoresis cannot deliver high-molecular beauty ingredients (collagen hyaluronic acid,


elastin). 5
Other introduction methods

Q What is the benefit of electroporation, compared with


other methods?

A Directly delivers beauty ingredients deep into the skin


tissue.
The electroporation creates instant pores
through a cell membrane and therefore
allow uptake even macro-molecular, such
as collagen and hyaluronic acid.

Iontophoresis and other methods cannot


deliver macro-molecular into skin.

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Summary of the characteristics of electroporation
 The electroporation method delivers both low or high molecular substances
into the skin without ionizing the balance.

 The method does not change the pH of the skin surface during treatments.
Therefore, your skin will not feel soreness or pain.

 Because this method is mild on skin, the sensitive skin around eyes can also
be treated.

 This treatment can also be combined with light therapy and supersonic waves.

 You will immediately notice a positive effect of the face treatment after the first
ten minutes.

 The method is suitable for customers who are not satisfied with mere short-
lived treatments.

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One latest mesotherapy machine 【EPOSKIN】

Facial, Body Slimming, Breast enhancement, Lip care, Scalp care


All in one machine!
[EPOSKIN] is the most advanced electroporation machine adjusted in particular to deliver WOVE
style beauty ingredients and growth factors deep into the skin.

Three electroporation probes as well as a cleansing probe are included.


Use a cleansing probe with supersonic wave vibration to thoroughly clean skin and remove dead skin cells.
This machine covers all types of treatments, such as facial, slimming, breast enhancement, lip care, and
scalp care.

Accessories probe
①Cleansing probe
②L probe
③S probe
④2 pin probes
Optional probe
⑤Probe for scalps
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Electroporation Treatment
EPOSKIN completes all treatments; facial, slimming,
breast enhancement, lips care, and scalp care.

◆Triple GF Essence Ⅱ
 Wrinkles and lines
 Skin texture
 Slack/Sagging skin
 Dry skin

◆Triple GF Essence Ⅱ+ VC20 Essence W


 Photo aging
 Dullness
 Blemishes, Freckles

◆Triple GF Essence Ⅱ+ GG Essence


 Tightening Enlarged pores
 Tightening of the skin

◆GF Cell Rebirth Ⅱ+ EP Gel


 The abdomen, Thigh ◆Scalp Care GF Essence
 Buttocks, Upper arm  Thin hair
 Cellulite  Hair loss

◆Triple GF Essence Ⅱ+ EP Gel


 Breast Enhancers The other combination including neck line, décolletage
treatment and more! 9

Commands a wide‐ranging treatment of electroporation!


[GF introduction course ] GF(Growth Factor) treatment
the ultimate skin regenerating program, based on regenerative medicine
The highly effective products and methods developed at the beauty dermatology WOVE
clinic, proven to be highly effective.

●[ Skin regeneration program ] treatment steps

① ② ③ ④ ⑤ ⑥ ⑦
Cleansing GF
Face Washing Peeling Neutralizing Exfoliating Electroporation Musk Moisturizing

① Cleansing ② Peeling ③ Neutralizer ④ Ultrasonic ⑤ injecting GF ⑥ Mask ⑦ Lotion


Cleansing Gel cleaning serum

A cleansing gel
that’s gentle on Pore cleansing with a
sensitive skin. cleansing probe, whose Revitalizing Mask G
Triple GF
supersonic wave essenceⅡ
Peeling Gel Neutramist vibration is Essence for face pack,
blending 3 types of GF Moisture Lotion
Washing 25000hz/second.
Removes old keratins, The ultimate anti-aging GFs and Glycyl
Fresh Washing Soap Lactic acid Peeling extract, developed from glycine. Harness aquaporin to
AHA neutralizer comedos, and
Gel safe and effective the field regenerative Normalizes ionized open up and allow
thoroughly calms peroxidative fatty acid.
A soap made medicine, EGF, FGF, skin, formulated GG moisture into your
the acidic skin This process enhances
from natural IGF, and HGF. to tighten enlarged skin cells.
the benefit of further
cleansing pores.
skincare treatment.
ingredients.

●[OPTIONS] Using the following products gives you a wide range of treatment options.
◆Special Essence◆
Blotches Acne Aging Dark circles
VC20 Essence W HX Essence
20% of this essence consists of Vitamin C.
Formulated with brightening ingredients, Formulated with Haloxyl to
such as highly-concentrated VC, arbutin, lighten dark circles around
kiribirth, and clairju, as well as white birch eyes. Increases elasticity of
sap. the skin around the eyes.

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[Scalp introduction course] GF(Growth Factor) treatment
the method developed at the anti-aging dermatology WOVE clinic,
proven to be highly effective

●[ Scalp course ] treatment steps

① ② ③ ④ ⑤ ⑥
Cleansing Shampoo GF introduction Massage Finishing
Conditioner
Or
Scalp& Hair
Mask
●Products and equipment for this course

① Cleansing ② Shampoo ③ Delivering GFs ④ Massage ⑤ Conditioner


with EPOSKIN

Cleansing Gel Premium Phyto Premium Phyto


Hair Shampoo Scalp Care
Hair Conditioner
GF Essence

A cleansing gel that is Improves the scalp with Formulated with natural Gently massage the entire Beauty serum conditioner.
gentle on sensitive skin. natural extract and essence and GFs to scalp. Adds bounce to hair fibers.
promotes hair-growth. condition scalp for
ideal hair-growth.

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What does EPOSKIN do?
Scalp, facial, breast firming, slimming, body shaping, all in one EPOSKIN!
Treats delicate features that iontophoresis, supersonic wave
introduction, and phototherapy cannot treat.
GFs (growth factors) and other hair-growth substances rejuvenate the scalp which
Scalp suffers from aging and environmental-stress. Prevents hair-loss and conditions the scalp
for ideal growth, volume, and healthy hair. For unisex use.

Eyelids/ The eyelids and skin around eyes sag or lose plumpness due to advancing age.
EPOSKIN delivers GFs deep into the skin and rejuvenates the cells in these delicate
Around Eyes areas. The region around eyes will appear more youthful.

Cheek/ EPOSKIN rejuvenates skin and tones up muscle to lift up the sagging cheeks or face line.
You’ll get young impression immediately. Not only face line, EPOSKIN tightens the skin
Face Line around of eyes and mouth.
EPOSKIN rejuvenates and gives volume to the lips. It brightens the color of lips by
Lips improving blood circulation. You’ll find you do not need lip sticks anymore.

Neck/ A targeted treatment uniquely designed to eliminate the signs of aging on your neck and
décolleté. EPOSKIN delivers plenty of essences into these areas to restore a youthful
décolleté appearance.
Unfortunately Cooper’s ligaments (connective tissue in the breasts) are very vulnerable
Breasts restores to the aging process and can lose their elasticity in no time at all. EPOSKIN restores
firmness to the breasts by delivering collagen and growth factors.
EPOSKIN delivers slimming essences into the body to reduce fat and achieve toning.
Body
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WOVE style Triple GF Essence (Anti-Aging Total Care Essence)
WOVE style Triple GF Essence Ⅱ
Formulated with four types of Growth Factors, originated in regeneration science.
This essence rejuvenates every cell. In addition, to help the cells generate ATP, the
essence injects a combination of vitamins, which is the same substance as that in a
beauty injection. ATP is essential for healthy and active cells.
Key ingredients

Growth Factors
EGF, aFGF, IGF, HGF

to promote ATP production, to infuse cells with energy


Vitamin C, A,E,B6, Coenzyme Q10. αLipoic acid

to prepare cells for GFs


GF Enhancer

3 major anti-aging substances


Acetyl hyaluronic acid (Super hyaluronic acid), high penetration collagen,

hydrolyzed elastin
anti skin-stress, Ant oxidation, Moisturizer
5mL×12
TRX, Centella asiatica extract, Dipotassium glycyrrhizinate, Raffinose 13
WOVE style GF Cell RebirthⅡ (Slimming GF essence)
WOVE style GF Cell RebirthⅡ
The ultimate slimming essence, formulated with IGF and Phosphatidylcholine; IGF originated in
regeneration science. Phosphatidylcholine is used in mesotherapy injections.

This essence produces multiple benefits: fat combustion, slimming, cellulite removal, and body
toning after slimming.
If you use EP-gel with this essence, you can treat wider area.

Key ingredients

to activate and rejuvenate cells


IGF

for fat combustion and burning


Phosphatidylcholine Carnitine

to prevent fat accumulation, to diminish cellulite


UCP peptide

to promote metabolism and blood circulation


Arginine / caffeine

to eject unwanted substances, to prevent swelling of body


Golden chamomile extract 60mL
Anti-inflammatory/ Firmness/ Moisture 14
Acetyl hyaluronic acid (Super hyaluronic acid)/ Dipotassium glycyrrhizinate/ Raffinose
WOVE style VC20 Essence (Brightening, Anti-Aging, for optional treatment)
WOVE style VC20 Essence
A brightening essence, formulated with a high concentration of VC (20%), arbutin,
kiribirth, clairju, and white birch sap.
This is the first professional-use brightening essence to include multiple brightening
substances.
Add this essence to Triple GF essence II to provide variety of treatments.
Key ingredients

to suppress melanin production


High-density VC

to suppress tyrosinase from becoming active


Arbutin

to suppress tyrosinase from producing enzymes


Kiribirth

to prevent keratinocyte from taking in melanin


Clairju
Hydrolyzed elastin

To promote cell differentiation, to remove active oxygen, to moisturize


30g
White birch sap 15
WOVEstyle HX Essence (to treat dark circles, for optional treatment)
WOVE style HX Essence
Formulated with Haloxyl to treat the problems around eyes. Haloxyl removes hemoglobin
accumulated in the epidermis and/or dermis. Hemoglobin produces dark circles under the
eyes. This essence also prevents pigmentation.

●Haloxyl also removes pigmented resolvent, such as biliverdin,


bilirubin, and iron.

●Packaged in a disposable bottle. Preservative-free.


One bottle can be used for two to three treatments.
1mL x 10 pcs.

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WOVE style Cleansing Gel
Oil-free, gentle even for sensitive skin
With special gel-structure to lift away makeup and sebum.
Oil-free gel cleansing which is mild to sensitive skin. It is washed away
clearly and do not put a burden on skin, unlike oil or cream cleansing do.

suitable for the person attaching eyelash-extension


500g

WOVE style Washing Soap

The rich foam removes dirt easily, so there’s no need for rubbing.
A soap made from natural cleansing ingredients, such as Soap
Nuts and other fatty acids from plants.

A soap well matured without drying in its production process. This


unusual production process achieves creamy lather which covers
your skin and cleans gently. 17
300mL
WOVE style Peeling Gel (ph3.3)

effective lactic acid peeling gel, developed by WOVE clinic


Formulated with lactic, acid which effectively and safely exfoliates
the skin.
It improves skin condition and successfully treats various types of
common problems, such as age-spots, wrinkles, and enlarged
pores.
300mL

WOVE style Neutramist (ph8.4)

α Hydroxy neutralizer, spray type that allows even spreading


AHA neutralizer. The spray action allows you to spray it on the skin
evenly, ensuring every part of the skin is thoroughly neutralized.
Soothes skin after exfoliation.

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300mL
WOVE style Revitalizing Mask G (Finishing Musk)

A mask, formulated with 3 types of growth factors,


used at the end of the treatment. Soothes, moisturizes, and
revitalizes skin. Maximizes the effect of Triple GF Essence II.
Contains all the essential factors for youthful skin, EGF, aFGF, and
IGF-1, to rejuvenate skin-cells which are differentiated by injecting
Triple GF Essence II. Effective treatment for winkles and sagging skin.
Contains Glycyl glycine to tighten enlarged pores. We recommend that
gauze be used to cover the face. 200mL

WOVE style EP Gel


supports the delivery of essences into the skin,
formulated with collagen and hyaluronic acid

After spreading GF Cell Rebirth II, add EP Gel in order to treat


larger areas of the body.
Includes collagen and hyaluronic acid to moisturize and smoothen
the skin.
This gel can also be used for body massage. 19
600g
WOVE style GF Moisture Lotion
Penetrates deep layers of the skin to hydrate every cell.
Harness aquaporin to open up and allow moisture into your skin
cells.
High pressure extraction placenta essence, EGF, plant stem cells,
and other clinical-grade anti-aging substances, fortify cells to
rejuvenate the skin.
Brightening substances, such as a Vitamin C derivatives and TPG2
485mL
prevent age spots and freckles..

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WOVE style Scalp Care GF Essence
(Scalp Care, Hair Growth Promoting Essence)
This introductory essence cures hair problems such as; hair loss, lime and
lifeless hair. Aging and/or ultraviolet rays can cause these kinds of troubles.
This essence conditions your scalp to aid hair growth. For professional and
unisex use.
●Formulated with 3 types of GF (Growth Factors).
⇒Peptide 「PB4」、「aFGF」、「IGF-1」 which have
properties similar to Thymosin β4
●Includes loquat leaf extract which encourages the
production of VEGF (skin growth in the blood vessels),
Swertia extract and arginine which all help to promote
healthy blood circulation. By using this essence, oxygen
and nourishment gently penetrate into the growth regions
of the scalp.
●Copper peptide prevents the male hormones from
combining with 5α reductase. If they are combined, they
would alter DHD which accelerates hair loss.
●Includes super hyaluronic acid which has twice the water-
retaining capacity of traditional hyaluronic acid. This new
type of hyaluronic acid moisturizes and softens the scalp, 10mL×12bottles
preventing skin-consolidation which would cause hair loss.
●Usage: Each bottle contains the appropriate amount for
one treatment.
What is the [growth factor]?
『Growth Factor』
Is essential for the increase and growth of cells.

Growth factors (GFs) naturally exist in the body to promote the increase
and growth of cells. However, GF declines with age: At a younger age,
physical injuries take a shorter time to heal, since younger people have a
greater amount of GFs.

Decrease of GFs accelerate aging.

GFs affects how youthful you look.

Supplying GFs stimulate the skin’s natural ability to heal aging-


damage and maintain beautiful skin structure.
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What are the 4 types of most effective GFs?
EGF⇒ Epidermal Growth Factor works on epidermal cells.
normalizes skin-turnover.
relieves age-spots or other aging signs.

aFGF ⇒ Acidic Fibroblast Growth Factor (works on dermal cells)


works on fibroblast to increase collagen and elastin and to
repair blood vessels.

IGF-1 ⇒ Insulin-like growth factor 1 (works on subcutaneous tissue)


reinforces the function of other GFs.
works on newborn tissue.

HGF ⇒ Hepatocyte Growth Factor


works on fibroblast to increase collagen, elastin,
and hyaluronic acid.
strengthens blood vessels.

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【Clinical result tested on consumer group.】

Different types of growth


factors maximizes
synergistic effect to
increase and grow cells.

Normal cell division EGFs are added Three types of Growth


Factors, EGF, FGF, IGF,
are added

EGF :
Dr. Stanley Cohen was awarded the 1986 Nobel Prize for his discovery of EGF.
At first, EGF was used in skin regeneration medicine, such as burn treatment,
keloid scars, and atopy.
It was extremely expensive at that time; 80 million yen (800,000 US dollar)
per 1 Kg.
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Arms treated with Cell RebirthⅡ
<Before> 30’s Female <After>

1.7cm
loss

1 treatment in every two weeks,


6 treatment session
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Knees treated with Cell RebirthⅡ
<Before> 30’s Female <After>

above-the-knee
1.5cm
loss

1 treatment in every week, 26


5 treatment session
Belly treated with Cell RebirthⅡ
<Before> 30’s Female <After>

4.7cm
loss

1 treatment in every week, 27


5 treatment session
Eye area treated with Triple GFⅡ
<Before> 50’s Female <After>

Crow’s-feet
looked softer and
8 treatment session smoother 28
Eye area treated with Triple GFⅡ

<Before> 50’s Female <After>

1 treatment session
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Hand treated with TGF-VC20 Essence W

<Before> 30’s Female <After>

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1 treatment session
Skin treated with TGF
(Improvement of the ruddy face)
<Before> 30’s Female <After>

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1 treatment session
Lips treated with Triple GF Essence
(plumping the lips)

<Before> 30’s Female <After>

1 treatment session
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Spotty Skin treated with TGF+VC20

<Before> 30’s Female <After>

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