A prolonged state of unconsciousness is known as coma.

A person is unresponsive to his or her

environment during this time. The person cannot be awakened by any stimulation. Most common
causes of coma are brain injury, brain stroke, brain swelling, blood sugar, brain infection, oxygen
deprivation, seizures etc. Treatment of coma is different for different causes, if there is a brain
infection, antibiotics are administered, Glucose is administered in an event of diabetic shock. Surgery
may also be necessary to relieve the pressure on the brain due to swelling or to remove a tumor.

https://www.omicsonline.org/scholarly/coma-journals-articles-ppts-list.php