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Immune System

(Prime Rhyme Time)


By: Lauren Witmer

Bacterium, fungus, virus, or disease These signals released upon injury or


infection, histamine is one of the main
They may not enter the body as they
tools
please
Stored in densely packed vesicles of
Committed to destroy and defend
mast cells,
Our immune system is our very best
Histamine is released at sites of
friend
damage, like magic or a secret spell
Innate immunity includes barrier and
It triggers nearby blood vessels to dilate
internal defenses
and become leaky,
This rapid, nonspecific response from
Fluid then leaks into neighboring tissues
birth protects at all expenses
which causes localized swelling (I know,
Pathogens are no match against the pretty freaky)
system
The body must fight in order to survive
Our skin helps us to resist ‘em
Receptor protein-tyrosine kinases are
As the first line of barrier defense, the important in this process; there’s around
skin blocks entry of many pathogens fifty-five

The second being the linings of the Antigens are any molecules capable of
digestive tracts in our abdomens inducing the immune system to respond

Saliva, tears, and mucous secretions all These foreign invaders bind to the B or
help bathe the exposed epithelial tissue T cell receptors in which it corresponds.

This washing inhibits colonization of Slower in response, adaptive and


fungi and bacteria without an issue. specific

Internal Defenses are what happens Acquired Immunity is quite terrific


inside us
Acquired Immunity include humoral and
There are many parts, as we will we cell-mediated
soon discuss
Humoral activates B cells, where
Inflammatory response alerts your plasma and memory cells are created.
body of a tiny boo-boo
What are B and T cells? You may ask
Pain and swelling are usually the result,
B cells remain and mature in the bone
who knew?
marrow proliferating and differentiating
This response comes with changes into memory B cells and antibody
brought about by signaling molecules, secreting plasma cells is its task.
Cell mediated activates cytotoxic T-cells
Immune System
(Prime Rhyme Time)
By: Lauren Witmer

Producing activated and memory Circulating through the body and


cytotoxic T- cells. releasing chemicals that lead to cell
death,
Helper T cells start it all
Natural killer cells don’t engulf
You can thank them for healing you
bacteria, unlike the rest.
after a fall
The chemicals released inhibit the
Helper T cells promotes the secretion
spread of viruses or cancers
of cytokines
The immune system has all of life’s
These send out signals to initiate the
answers.
production of antibodies, there’s many
kinds Detecting the abnormal collection of
surface protein characteristics of some
Antibodies neutralize pathogens and
virus-infected and cancerous cells,
activate t cells that will kill the infected
cells Innate defenses in vertebrates always
excel thanks to these natural killer cells
Activated only when a foreign molecule
can bind specifically to the antigen Active immunity can develop through
receptor of the T- cell. the introduction of antigens into the
body through immunization
Cells within the body capable of
engulfing and absorbing bacteria, Today these immunizations are called
vaccines; they save us from repeated
Phagocytes can break down and ingest
foreign cell contamination
those germs like it’s in the cafeteria
Vaccines contain inactivated bacterial
The two main types are neutrophils and
toxins, killed or weakened pathogens,
macrophages found in mammals,
and even genes encoding microbial
They migrate through the body, always proteins.
in a scramble
Vaccines, like varicella, influenza and
Attracted by signals from infected MMR, are needed by all means.
tissues like the blood,
These immunizations induce a primary
Neutrophils attack and engulf immune response that can last around
pathogens like a flood 10-17 days to the pathogen from the
vaccine
The bigger the better, as they always
say The first time that the immune system
comes in contact with a certain antigen
Macrophages are big, and destroy any is known as primary immune response,
foreign invaders in their way the second time it comes around, it’s
definitely foreseen.
Immune System
(Prime Rhyme Time)
By: Lauren Witmer

Whenever that pathogen is encountered The lymph nodes become swollen with
again it only takes 2-7 days to defeat it, infection, no wonder it’ ns called
inflammatory
The secondary immune response will
be able to fight it off faster and stronger, I know that these processes sound
with memory cells that seek it intense and quite difficult,
Memory cells are long-lived B cells that But really doing this process every
will attack a certain pathogen whenever second is quite typical
it returns
I know there aren’t any fireworks,
B cells divide into plasma cells and
Basically that’s how the immune system
memory cells which a certain pathogen
works
that it learns.
Plasma cells secrete antibodies that fit
with antigen receptors like a lock and
key
Oh boy this is so exciting, I might
actually pee
These antibodies neutralize toxins and
immobilize molecules that are foreign
They bind specifically to an antigen and
targets for destructin’
Killer T- cells fight pathogens when
helpers T cells give the signal
Sometimes known as cytotoxic t cells,
they use proteins to kill infected cells,
really quite simple.
Suppressor T- cells inhibit cell division,
therefore preventing uncontrolled cell
growth,
Lymphatic vessels and lymph nodes
trap foreign substances, the lymphatic
system consists of them both
Consisting of B and T cells and all their
glory