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Abstract
Bael, Aegle marmelos (Linn.) Correa ex Roxb., a tree of Indian origin is known
from pre-historic time. It has a great mythological significance for Hindus. Utilization of bael in
day-to-day life has great nutritional, environmental as well as commercial importance. It has been
in use from time immemorial in traditional systems of medicine for relieving constipation, diarrhoea,
dysentery, peptic ulcer and respiratory infections. Important medicinal properties of bael are
antidiabetic, antimicrobial, anti-inflammatory, antipyretic, analgesic, cardioprotective,
antispermatogenic, anticancer and radioprotective. The present review deals with general and
chemical profile and its economic importance including medicinal and other uses.
Keywords: Bael, Aegle marmelos, Medicinal plant.
IPC code; Int. cl.8 — A61K 36/00, A61K 36/75, A23L 1/00, A23L 2/02
nutritive and therapeutic are getting 1629 A.D. noticed the presence of this Cultivars
popularized in Indian as well as in tree along with other trees in this region16. In India, the plant is widely
international market. In India, there is a It is also grown in some Egyptian cultivated particularly in Uttar Pradesh
large area, which is waste land and and gardens in Surinam and Trinidad. and Bihar. So far around twelve
remains unproductive which can be Specimens of Bael have been procured distinct cultivars, viz. ‘Basti No.1’, ‘Kagzi
exploited with bael cultivation. It can be and maintained in Citrus Collection in Gonda’, ‘Gonda No.1’, ‘Gonda No.2’,
cultivated commercially on waste land and Florida 17. Bael fruit has been used ‘Gonda No.3’, ‘Kagzi Etawah’, ‘Sewan
unproductive land for the upliftment of traditionally in making paints in Burma18. Large’, ‘Mirzapuri’, ‘Deoria Large’,
farmers14. In Bangladesh, the tree has been used for ‘Chakaiya’, ‘Baghel’ and ‘Lamba’ have
Bael plant acts as a ‘Sink’ for fertility control and antiproliferative and been reported. Out of these four cultivars
chemical pollutants as it absorbs in Sri Lanka it has been used for its ‘Kagzi Etawah’, ‘Sewan Large’, ‘Mirzapuri’
poisonous gases from atmosphere and hypoglycemic activities19-21. Bael fruit was and ‘Deoria Large’ have been found to be
make them inert or neutral. It is a member introduced in Europe in 1959(Ref.22). superior and excellent in taste and other
of plant species group known as ‘Climate The tree has also been reported to be qualities26.
Purifiers’, which emit greater percentage cultivated in Ceylon, Northern Malaya, Java
of oxygen in sunlight as compared to other and Philippine Island where it was first Chemical composition
plants. The tree is also considered under fruited in 1914(Ref.23). Various chemical constituents
the category of ‘Fragrant’ species, whose like alkaloids, coumarins and steroids
flowers and volatile vapours neutralize bad Bael in Mythology have been isolated and identified from
smell of pterified organic matter or Hindus hold the tree in great different parts of tree, such as leaves,
decaying refuge and thus save human life venerations. It is one of the most sacred fruits, wood, root and bark.
from bacterial attack by making them trees of India. The leaves are ternate and
inert and deodorizing the bad odour of hence one of the vernacular names is Coumarins
the air15. Tripatra24. It is generally cultivated near Marmelosin, marmesin,
The present review deals with temples and is offered to Lord Shiva, imperatorin, marmin, alloimperatorin,
general and chemical profile of the tree whose worship cannot be completed methyl ether, xanthotoxol, scoparone,
and its economic value including without the leaves of this tree. Lord Shiva scopoletin, umbelliferone, psoralen and
medicinal and other uses. is believed to live under the Bael tree. It marmelide 27 . Marmenol, a
is also called Shivadurme, the tree of 7-geranyloxycoumarin [7-(2, 6-dihydroxy-
Origin and Distribution Shiva. According to Hindu mythology, the 7-methoxy-7-methyl-3-octaenyloxy)
The Bael tree has its origin from tree is another form of Lord coumarin] has also been reported28.
Eastern Ghats and Central India. It is Kailashnath 12. It is also sacred to
indigenous to Indian subcontinent and Parvati and is the Vilva rupra, one of Alkaloids
mainly found in tropical and subtropical the Patricas, or nine forms of Goddess Aegelin, aegelenine, marmeline,
regions. The tree is also found as a wild Kali. The planting of this tree by the dictamine, fragrine (C 13 H 11 O 3N), O-
tree, in lower ranges of Himalayas up to waysides gives long life. Its leaves are also methylhalfordinine, O
an elevation of 500 meters. Bael is found used as enchantments. It is incumbent isopentenylhalfordinol27, N-2-[4-(3’,3’-
growing along foothills of Himalayas, Uttar upon all Hindus to cultivate and cherish dimethylallyloxy) phenyl]ethyl cinnamide,
Pradesh, Bihar, Chattisgarh, Uttaranchal, this tree and it is sacrilege to cut it down11. N-2-hydroxy-2-[4-(3’,3’-dimethylallyloxy)
Jharkhand, Madhya Pradesh, The Deccan The mentions of plant have also been phenyl]ethyl cinnamide, N-4
Plateau and along the East Coast8, 12. found in ancient Indian scriptures such methoxystyryl cinnamide, N-2- hydroxy-2-
Hiuen Tsiang, the Chinese as Vedas and Purana25 like Yajurveda (4-hydroxyphenyl) ethyl cinnamide29, 30, O-
Buddhist pilgrim who came to India in and Mahabharata12. (3,3-dimethylallyl) halofordinol, N-2-
172 Natural Product Radiance
Review Article
Table 1 : Nutritional value of Bael fruit (% or per 100g)12, 39, 40 T-lymphoid Jurhat, Beta-lymphoid
Raji, Erythro leukemic HEL 20.
Components Value (%) Components Value (%) Extract of A. marmelos is
antiproliferative but it produces effect on
Water (moisture) 64.2 Potassium 0.6
MCF-7 and MDA-MB-231 breast
Protein 1.8 Iron 0.3
cancer cell line when it is in high
Fat 0.2 Vitamin A (IU) 186
concentration56-58.
Mineral 1.5 Vitamin B1 0.01
Fibre 2.2 Nicotinic acid 0.9
Cardioprotective effects
Carbohydrate 30.6 Riboflavin 1.2
Calcium 0.09 Vitamin C 0.01
The leaf extract has preventing
Phosphorus 0.05 Calorific value 129
effects in isoprenaline (isoproterenol)-
induced myocardial infarction in rats. The
activity of creatine kinase and lactate
expanded bael fruit processing as highly sometime. It is also a valuable remedy for
dehydrogenase was significantly increased
promising. The young leaves and shoots chronic dysenteric conditions characterized
in serum and decreased significantly in
are eaten as a vegetable in Thailand and by alternate diarrhoea and constipation43, 44.
heart of isoprenaline-treated rats59. Use of
used as seasonal food in Indonesia. These Its use has also been reported in the cases
Bael as cardiac depressant and in
are said to reduce the appetite. An infusion of amoebic dysentery45.
palpitation has also been reported10-12, 18.
of the flowers is used as a cooling drink23.
Hypoglycemic/
Antispermatogenic activity
Medicinal uses Antidiabetic activity
The leaf extract possesses
Leaf extract has been used in
anti-spermatogenic activity as it resists
Diarrhoea and Dysentery Ayurveda as a medicine for diabetes. It
the process of spermatogenesis and decreases
The unripe or half ripe fruit is enhances the ability to utilize the external
sperm motility in rats60. Leaves were
the most effective remedy for chronic glucose load in the body by stimulation
used for fertility control in Bangladesh29, 39.
diarrhoea and dysentery without fever. Best of glucose uptake similar to insulin46, 47.
results are obtained by the use of dried Bael extract significantly lowers blood
Antimicrobial/Antifungal activity
fruit or its powder. The fruit, when it is urea and cholesterol in experimental
Bael extract manifests antiviral
still green, is sliced and dried in the sun. diabetic animals21, 48. Extract also decreases
and antimicrobial activities. It has been
The dried fruit slices are reduced into oxidative stress in experimental diabetic
found active against various species such
powder and preserved in air-tight bottles. animals as indicated by significant
as Staphylococcus aureus, S.
The unripe fruit can also be baked and reduction in lipid peroxidation,
epidermidis, Proteus vulgaris,
taken with jaggery or brown sugar41. The conjugated diene and hydroperoxide level
Escherichia coli, Salmonella
fruit appears to have little effect in acute and increased levels of superoxide
typhimurium and Bacillus subtilis. It
dysentery when there is definite sensation dismutase, catalase, glutathione
has also been used for Ranikhet disease
to defecate without the significant amount peroxidase and glutathione levels in serum
virus and intestinal parasites 9, 27. The
of faeces, blood and mucus alone are as well as liver49-54. Juice of leaves is
essential oil isolated from the leaves of
passed. The powdered drug is specially employed as anti-diabetic drug in Unani
Bael exhibits variable efficiency against
recommended in sub-acute or chronic system of medicine also55.
different fungal isolates and causes
dysentery. After the use of the fruit powder
concentration as well as time dependent
in these conditions, the blood gradually Anticancer activity
inhibition of spore germination of all the
disappears and the stools resume a more Bael inhibited in vitro
fungi tested, including most resistant
feculent and solid form42. The mucus also proliferation of human tumour cell lines
fungus, Fusarium udum61.
disappears after continued use for including the lecukenic K562,
174 Natural Product Radiance
Review Article
Radioprotective effect fruit with mustard oil for the treatment treatment of leucorrhoea, conjunctivitis
Treatment with extract of bael of burn cases. One part of powder and and deafness. Fruits give feeling of
reduces the severity of symptoms of two parts of mustard oil are mixed and is freshness and energy71, 72. It is used as
radiation induced sickness and increases applied externally18, 67. carminative and astringent and used in
survival in mice. The radio protective thyroid related disorders73. It is also used
action might be due to free-radical Peptic ulcer in treatment of snakebite. It is a cardiac
scavenging and arrest of lipid peroxidation An infusion of leaves is an stimulant74. Applications have also been
accompanied by an elevation in effective remedy for peptic ulcer. The reported in anaemia, fractures, swollen
glutathione concentration in liver, kidney, leaves are soaked overnight in water. This joints, pregnancy troubles, typhoid40,
stomach and intestine62, 63. water is strained and taken as a drink in coma 75, colitis 37, bleeding sores and
the morning. The pain and discomfort are cramps15. It is also used as anthelmintic.
Antipyretic and Analgesic activities relieved when this treatment is continued It is used in treatment of acute
Bael extract exhibits antipyretic, for a few weeks. The fruit taken in the shigellosis76, as diuretic, in gonorrhoea11
anti-inflammatory and analgesic activities, form of beverage has also great healing and in conjuctivitis72. The powder is used
as it has shown a significant inhibition of properties on account of its mucilage, as stomachic. It is used in the treatment of
the carrageenan induced paw odema, which forms a coating on the stomach irritable bowel syndrome77.
cotton-pellet granuloma and paw itching mucosa and thus helps in the healing of
in mice and rats64. It is also used as ulcers68, 69. Conclusion
febrifuge in night and intermittent Looking upon wide prospects
fever11, 15, 37. Respiratory infections and potential of bael for various purposes,
Medicated oil prepared from it is worthwhile to cultivate this plant on
Constipation leaves gives relief from recurrent cold and large scale especially on unproductive and
Ripe fruit is regarded as best of respiratory infections. The juice extracted wasteland. This will help in financial
all laxatives. It cleans and tones up the from leaves is mixed with equal quantity upliftment of poor and landless farmers.
intestines. Its regular use for two to three of sesame oil and heated thoroughly, a Furthermore, systematic and scientific
months helps in evacuation of even the few seeds of black pepper and half a research is required to explore the
old accumulated faecal matter from the teaspoonful of black cumin are added to maximum potential of this under-utilized
bowels65. For best result, it should be taken the hot oil, and then it is removed from plant. Authors are of the opinion that we
in the form of Sharbat, which is the fire and stored for use when necessary. Indians equipped with modern scientific
prepared from the pulp of the ripe fruit. A teaspoonful of this oil should be techniques and enriched with strong
After breaking the shell, the seeds are massaged onto the scalp before a head traditional knowledge are best suited and
removed and contents are then taken out bath. Its regular use builds up resistance well placed harness to maximum potential
with the help of a spoon and passed against cold and cough. A common of this Plant of Panacea for human
through a sieve. Milk and sugar may be practice in South India is to give the juice and environmental well-being.
added to make it more palatable. The pulp of leaves to bring relief from wheezing
of ripe fruit can also be taken with the cough and respiratory spasm. The leaf Acknowledgements
spoon without addition of milk and sugar. juice is mixed in warm water with a little Authors are thankful to Sh. Desh
About 60g of the fruit/edible part is pepper and is given as a drink40, 70. Kamal Bishnoi, Director, Lord Shiva
sufficient for an adult66. College of Pharmacy, Sirsa, Haryana for
Miscellaneous properties providing necessary facilities and Prof (Dr.)
In Burn cases Bael leaves are useful in jaundice D.N. Mishra, Chairman, Dept. of Pharm.
The traditional healers of and in the treatment of wounds. The Sciences, Guru Jambheshwar University,
southern Chhatisgarh use dry powder of extract of leaves is beneficial in the Hisar, Haryana for his valuable guidance.
Vol 6(2) March-April 2007 175
Review Article
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