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Natural Product Radiance, Vol. 6(2), 2007, pp.

171-178 Review Article

A review on Bael tree


Prabodh Chander Sharma*, Vivek Bhatia, Nitin Bansal and Archana Sharma
Lord Shiva College of Pharmacy
Post Box No.63, Sirsa-125 055, Haryana, India
*Correspondent author, E-mail: sharma_prabodh@rediffmail.com
Phone: 09416025460; Fax: +91-1666-242695
Received 16 January 2006; Accepted 7 December 2006

Abstract
Bael, Aegle marmelos (Linn.) Correa ex Roxb., a tree of Indian origin is known
from pre-historic time. It has a great mythological significance for Hindus. Utilization of bael in
day-to-day life has great nutritional, environmental as well as commercial importance. It has been
in use from time immemorial in traditional systems of medicine for relieving constipation, diarrhoea,
dysentery, peptic ulcer and respiratory infections. Important medicinal properties of bael are
antidiabetic, antimicrobial, anti-inflammatory, antipyretic, analgesic, cardioprotective,
antispermatogenic, anticancer and radioprotective. The present review deals with general and
chemical profile and its economic importance including medicinal and other uses.
Keywords: Bael, Aegle marmelos, Medicinal plant.
IPC code; Int. cl.8 — A61K 36/00, A61K 36/75, A23L 1/00, A23L 2/02

Introduction pharmaceutical industries (29 indigenous


World Health Organization has species and 11 exotic). Similarly, aroma
listed over 21000 plant species used chemical industries are currently using
around the world for medicinal purposes. only 42 plant species from a diverse
In India, about 2500 plant species genetic base of more than 1300 plant
belonging to more than 1000 genera are species known for their aromatic
being used in indigenous system of properties. Among these 42 plant species,
20 are indigenous and rest being of exotic Aegle marmelos fruiting branch
medicine1. In terms of both quantity and
value of the medicinal plants exported, introduction6. Tandon and Thayil stated
India ranks second in the world2. India is that India’s medicinal heritage; one of the Marredy (Malyalam); Belo (Oriya);
one of the 12 mega biodiversity centers world’s oldest living traditions has been Vilvama, Vilva marum (Tamil); and
of the world with 16 agro-climatic zones3,4 in danger of sliding down towards Bilva, Bilva pandu (Telugu).
and has about 45000 plant species of extinction 7. Bael, Aegle marmelos Bael is known in India from pre-
which 15000 species are of flowering (Linn.) Correa ex Roxb., a plant of historic time13 and has been mentioned
plants having about 7000 species Indian origin having tremendous in the ancient system of medicine. It has
identified as medicinal plants5. There are therapeutic potential is not fully utilized. a great mythological significance also.
about 400 families in the world of the It belongs to family Rutaceae, the family Every part of plant such as fruit, seed,
flowering plants, of which at least 315 of citrus fruits. It is known with different bark, leaf and root are important
are represented by India4. Despite of our names in different languages8-12. Bel, Beli, ingredients of several traditional
rich heritage and knowledge of the use of Belgiri (Hindi); Bilva, Shivadruma, formulations. Due to its curative
plant drugs, little attention has been paid Shivaphala, Vilva (Sanskrit); Bael, properties, it is one of the most useful
to harness the inexpensive remedies to Bengal quince, Golden apple (English); medicinal plants of India. It is utilized in
modern requirements3. Only 40 plant Bel, Bel Kham (Urdu); Bel (Assamese day-to-day life in various forms. The
species are currently used by the and Marathi); Bilivaphal (Gujrati); products obtained from bael, being highly

Vol 6(2) March-April 2007 171


Review Article

nutritive and therapeutic are getting 1629 A.D. noticed the presence of this Cultivars
popularized in Indian as well as in tree along with other trees in this region16. In India, the plant is widely
international market. In India, there is a It is also grown in some Egyptian cultivated particularly in Uttar Pradesh
large area, which is waste land and and gardens in Surinam and Trinidad. and Bihar. So far around twelve
remains unproductive which can be Specimens of Bael have been procured distinct cultivars, viz. ‘Basti No.1’, ‘Kagzi
exploited with bael cultivation. It can be and maintained in Citrus Collection in Gonda’, ‘Gonda No.1’, ‘Gonda No.2’,
cultivated commercially on waste land and Florida 17. Bael fruit has been used ‘Gonda No.3’, ‘Kagzi Etawah’, ‘Sewan
unproductive land for the upliftment of traditionally in making paints in Burma18. Large’, ‘Mirzapuri’, ‘Deoria Large’,
farmers14. In Bangladesh, the tree has been used for ‘Chakaiya’, ‘Baghel’ and ‘Lamba’ have
Bael plant acts as a ‘Sink’ for fertility control and antiproliferative and been reported. Out of these four cultivars
chemical pollutants as it absorbs in Sri Lanka it has been used for its ‘Kagzi Etawah’, ‘Sewan Large’, ‘Mirzapuri’
poisonous gases from atmosphere and hypoglycemic activities19-21. Bael fruit was and ‘Deoria Large’ have been found to be
make them inert or neutral. It is a member introduced in Europe in 1959(Ref.22). superior and excellent in taste and other
of plant species group known as ‘Climate The tree has also been reported to be qualities26.
Purifiers’, which emit greater percentage cultivated in Ceylon, Northern Malaya, Java
of oxygen in sunlight as compared to other and Philippine Island where it was first Chemical composition
plants. The tree is also considered under fruited in 1914(Ref.23). Various chemical constituents
the category of ‘Fragrant’ species, whose like alkaloids, coumarins and steroids
flowers and volatile vapours neutralize bad Bael in Mythology have been isolated and identified from
smell of pterified organic matter or Hindus hold the tree in great different parts of tree, such as leaves,
decaying refuge and thus save human life venerations. It is one of the most sacred fruits, wood, root and bark.
from bacterial attack by making them trees of India. The leaves are ternate and
inert and deodorizing the bad odour of hence one of the vernacular names is Coumarins
the air15. Tripatra24. It is generally cultivated near Marmelosin, marmesin,
The present review deals with temples and is offered to Lord Shiva, imperatorin, marmin, alloimperatorin,
general and chemical profile of the tree whose worship cannot be completed methyl ether, xanthotoxol, scoparone,
and its economic value including without the leaves of this tree. Lord Shiva scopoletin, umbelliferone, psoralen and
medicinal and other uses. is believed to live under the Bael tree. It marmelide 27 . Marmenol, a
is also called Shivadurme, the tree of 7-geranyloxycoumarin [7-(2, 6-dihydroxy-
Origin and Distribution Shiva. According to Hindu mythology, the 7-methoxy-7-methyl-3-octaenyloxy)
The Bael tree has its origin from tree is another form of Lord coumarin] has also been reported28.
Eastern Ghats and Central India. It is Kailashnath 12. It is also sacred to
indigenous to Indian subcontinent and Parvati and is the Vilva rupra, one of Alkaloids
mainly found in tropical and subtropical the Patricas, or nine forms of Goddess Aegelin, aegelenine, marmeline,
regions. The tree is also found as a wild Kali. The planting of this tree by the dictamine, fragrine (C 13 H 11 O 3N), O-
tree, in lower ranges of Himalayas up to waysides gives long life. Its leaves are also methylhalfordinine, O
an elevation of 500 meters. Bael is found used as enchantments. It is incumbent isopentenylhalfordinol27, N-2-[4-(3’,3’-
growing along foothills of Himalayas, Uttar upon all Hindus to cultivate and cherish dimethylallyloxy) phenyl]ethyl cinnamide,
Pradesh, Bihar, Chattisgarh, Uttaranchal, this tree and it is sacrilege to cut it down11. N-2-hydroxy-2-[4-(3’,3’-dimethylallyloxy)
Jharkhand, Madhya Pradesh, The Deccan The mentions of plant have also been phenyl]ethyl cinnamide, N-4
Plateau and along the East Coast8, 12. found in ancient Indian scriptures such methoxystyryl cinnamide, N-2- hydroxy-2-
Hiuen Tsiang, the Chinese as Vedas and Purana25 like Yajurveda (4-hydroxyphenyl) ethyl cinnamide29, 30, O-
Buddhist pilgrim who came to India in and Mahabharata12. (3,3-dimethylallyl) halofordinol, N-2-
172 Natural Product Radiance
Review Article

ethoxy-2-(4-methoxy phenyl) ethyl Utilization has been identified as suitable windbreak


cinnamide, N-2-methoxy-2-[4-(3’,3’- or wind barrier14.
dimethylallyloxy)phenyl] ethylcinnamide, General uses In Indonesia, it is a common
N-2-methoxy-2-(4-methoxyphenyl)- Every part of the bael tree is practice to take bael fruit in breakfast
ethylcinnamide31, 32. utilized for various purposes. The wood either by cutting or breaking open the soft
is yellowish or grayish white, hard fruits and eating the pulp of fruit dressed
Polysaccharides lustrous, aromatic when freshly cut. It in palm sugar. Beating the seeded pulp
Galactose, arabinose, uronic acid takes a fine polish and is suitable for together with milk and sugar makes a
and L-rhamanose are obtained on house building, cart construction, popular drink called Sharbat in India.
hydrolysis33. agricultural implements, carving, pestles, The fruits carry large quantity of tenacious
tool handles, combs, etc., but the tree is transparent gluten, which becomes hard
Seed Oil too valuable to be felled for its timber18, 36. on drying but continues to be transparent
Composed of palmitic, stearic, Wood is employed for making producer and when ripe and mixed with juice of
oleic, linoleic and linolenic acid27. gas plant37 and also used for making small tamarind, forms an agreeable drink. These
household articles and cattle sheds12. The drinks are consumed less as food or
Tannins twigs and leaves are used as fodder. The refreshment than for their medicinal
The maximum tannin content in twigs are also used as tooth brushes or effects. Mature (full grown) but still
bael fruit was recorded in the month of chew-sticks. A sweet-scented water is unripe fruits are made into jam with
January. There is as much as 9% tannin in distilled from the flowers. Leaf juice is addition of citric acid. The pulp is also
the pulp of wild fruits, less in cultivated applied to the body before taking a bath converted into marmalade or syrup, which
type. Tannin is also present in leaves as to remove bad smell25. The most valuable is used as food material as well as a
skimmianine. part of the tree is the fruit. A yellow dye is therapeutic agent in relieving diarrhoea and
obtained from the unripe rind, which is dysentery. A firm jelly is made from the pulp
Carotenoids used with myrobalans in calico printing. alone or combined with guava to modify the
Carotenoids are responsible for In Siam, the shell is used for scenting hair astringent flavour. The pulp is also pickled12, 38.
imparting pale colour to fruit. oil. On distillation, the rind yields the
essential oil known as ‘Marmelle oil’. The Nutritional value
Marmelosin, skimmianine and sweet aromatic fruit pulp is very nutritious, Physico-chemical studies have
umbelliferone are the therapeutically which is used for making Sharbat36. revealed that bael fruit is rich in mineral
active principles of bael plant. Mixed with lime the pulp makes a and vitamin contents 26, 39, 40 . Major
tenacious cement, which is used for the components of nutritional importance are
Minor constituents like ascorbic construction of wells. It is also employed listed in Table 1. Bael pulp is steeped in
acid, sitosterol, crude fibres, tannins, as a varnish (where a polished surface is water, strained, preserved with 350 ppm
α-amyrin, carotenoids, crude proteins required) for pictures and adds brilliancy SO 2 , blended with 30% sugar, then
are also present. Roots of the tree have to water colour paints12. The pulp is often dehydrated for 15 hours at 120°F
also been found to contain used as a substitute for soap for washing (48.89°C) and pulverized. The powder is
psoralen, xanthotoxin scopoletin and clothes as it has detergent properties36. enriched with 66mg/100g Ascorbic acid
tembamide27, 34. The dried fruits, after separating the pulp and can be stored for 3 months for making
from the rind, are used as pill boxes for cold drinks (Squashes). Bael fruit toffee
Compounds such as praealtin D, keeping valuable medicine, sacred ashes is prepared by combining the pulp with
trans-cinnamic acid, 4- methoxy benzoic and snuff balls. Gum from stem is non sugar, glucose, skim milk powder and
acid, betulunic acid, and montanin have edible but acts as a good adhesive and hydrogenated fat. Indian food
also been reported35. used often for book binding12, 18. The tree technologists view the prospects for

Vol 6(2) March-April 2007 173


Review Article

Table 1 : Nutritional value of Bael fruit (% or per 100g)12, 39, 40 T-lymphoid Jurhat, Beta-lymphoid
Raji, Erythro leukemic HEL 20.
Components Value (%) Components Value (%) Extract of A. marmelos is
antiproliferative but it produces effect on
Water (moisture) 64.2 Potassium 0.6
MCF-7 and MDA-MB-231 breast
Protein 1.8 Iron 0.3
cancer cell line when it is in high
Fat 0.2 Vitamin A (IU) 186
concentration56-58.
Mineral 1.5 Vitamin B1 0.01
Fibre 2.2 Nicotinic acid 0.9
Cardioprotective effects
Carbohydrate 30.6 Riboflavin 1.2
Calcium 0.09 Vitamin C 0.01
The leaf extract has preventing
Phosphorus 0.05 Calorific value 129
effects in isoprenaline (isoproterenol)-
induced myocardial infarction in rats. The
activity of creatine kinase and lactate
expanded bael fruit processing as highly sometime. It is also a valuable remedy for
dehydrogenase was significantly increased
promising. The young leaves and shoots chronic dysenteric conditions characterized
in serum and decreased significantly in
are eaten as a vegetable in Thailand and by alternate diarrhoea and constipation43, 44.
heart of isoprenaline-treated rats59. Use of
used as seasonal food in Indonesia. These Its use has also been reported in the cases
Bael as cardiac depressant and in
are said to reduce the appetite. An infusion of amoebic dysentery45.
palpitation has also been reported10-12, 18.
of the flowers is used as a cooling drink23.
Hypoglycemic/
Antispermatogenic activity
Medicinal uses Antidiabetic activity
The leaf extract possesses
Leaf extract has been used in
anti-spermatogenic activity as it resists
Diarrhoea and Dysentery Ayurveda as a medicine for diabetes. It
the process of spermatogenesis and decreases
The unripe or half ripe fruit is enhances the ability to utilize the external
sperm motility in rats60. Leaves were
the most effective remedy for chronic glucose load in the body by stimulation
used for fertility control in Bangladesh29, 39.
diarrhoea and dysentery without fever. Best of glucose uptake similar to insulin46, 47.
results are obtained by the use of dried Bael extract significantly lowers blood
Antimicrobial/Antifungal activity
fruit or its powder. The fruit, when it is urea and cholesterol in experimental
Bael extract manifests antiviral
still green, is sliced and dried in the sun. diabetic animals21, 48. Extract also decreases
and antimicrobial activities. It has been
The dried fruit slices are reduced into oxidative stress in experimental diabetic
found active against various species such
powder and preserved in air-tight bottles. animals as indicated by significant
as Staphylococcus aureus, S.
The unripe fruit can also be baked and reduction in lipid peroxidation,
epidermidis, Proteus vulgaris,
taken with jaggery or brown sugar41. The conjugated diene and hydroperoxide level
Escherichia coli, Salmonella
fruit appears to have little effect in acute and increased levels of superoxide
typhimurium and Bacillus subtilis. It
dysentery when there is definite sensation dismutase, catalase, glutathione
has also been used for Ranikhet disease
to defecate without the significant amount peroxidase and glutathione levels in serum
virus and intestinal parasites 9, 27. The
of faeces, blood and mucus alone are as well as liver49-54. Juice of leaves is
essential oil isolated from the leaves of
passed. The powdered drug is specially employed as anti-diabetic drug in Unani
Bael exhibits variable efficiency against
recommended in sub-acute or chronic system of medicine also55.
different fungal isolates and causes
dysentery. After the use of the fruit powder
concentration as well as time dependent
in these conditions, the blood gradually Anticancer activity
inhibition of spore germination of all the
disappears and the stools resume a more Bael inhibited in vitro
fungi tested, including most resistant
feculent and solid form42. The mucus also proliferation of human tumour cell lines
fungus, Fusarium udum61.
disappears after continued use for including the lecukenic K562,
174 Natural Product Radiance
Review Article

Radioprotective effect fruit with mustard oil for the treatment treatment of leucorrhoea, conjunctivitis
Treatment with extract of bael of burn cases. One part of powder and and deafness. Fruits give feeling of
reduces the severity of symptoms of two parts of mustard oil are mixed and is freshness and energy71, 72. It is used as
radiation induced sickness and increases applied externally18, 67. carminative and astringent and used in
survival in mice. The radio protective thyroid related disorders73. It is also used
action might be due to free-radical Peptic ulcer in treatment of snakebite. It is a cardiac
scavenging and arrest of lipid peroxidation An infusion of leaves is an stimulant74. Applications have also been
accompanied by an elevation in effective remedy for peptic ulcer. The reported in anaemia, fractures, swollen
glutathione concentration in liver, kidney, leaves are soaked overnight in water. This joints, pregnancy troubles, typhoid40,
stomach and intestine62, 63. water is strained and taken as a drink in coma 75, colitis 37, bleeding sores and
the morning. The pain and discomfort are cramps15. It is also used as anthelmintic.
Antipyretic and Analgesic activities relieved when this treatment is continued It is used in treatment of acute
Bael extract exhibits antipyretic, for a few weeks. The fruit taken in the shigellosis76, as diuretic, in gonorrhoea11
anti-inflammatory and analgesic activities, form of beverage has also great healing and in conjuctivitis72. The powder is used
as it has shown a significant inhibition of properties on account of its mucilage, as stomachic. It is used in the treatment of
the carrageenan induced paw odema, which forms a coating on the stomach irritable bowel syndrome77.
cotton-pellet granuloma and paw itching mucosa and thus helps in the healing of
in mice and rats64. It is also used as ulcers68, 69. Conclusion
febrifuge in night and intermittent Looking upon wide prospects
fever11, 15, 37. Respiratory infections and potential of bael for various purposes,
Medicated oil prepared from it is worthwhile to cultivate this plant on
Constipation leaves gives relief from recurrent cold and large scale especially on unproductive and
Ripe fruit is regarded as best of respiratory infections. The juice extracted wasteland. This will help in financial
all laxatives. It cleans and tones up the from leaves is mixed with equal quantity upliftment of poor and landless farmers.
intestines. Its regular use for two to three of sesame oil and heated thoroughly, a Furthermore, systematic and scientific
months helps in evacuation of even the few seeds of black pepper and half a research is required to explore the
old accumulated faecal matter from the teaspoonful of black cumin are added to maximum potential of this under-utilized
bowels65. For best result, it should be taken the hot oil, and then it is removed from plant. Authors are of the opinion that we
in the form of Sharbat, which is the fire and stored for use when necessary. Indians equipped with modern scientific
prepared from the pulp of the ripe fruit. A teaspoonful of this oil should be techniques and enriched with strong
After breaking the shell, the seeds are massaged onto the scalp before a head traditional knowledge are best suited and
removed and contents are then taken out bath. Its regular use builds up resistance well placed harness to maximum potential
with the help of a spoon and passed against cold and cough. A common of this Plant of Panacea for human
through a sieve. Milk and sugar may be practice in South India is to give the juice and environmental well-being.
added to make it more palatable. The pulp of leaves to bring relief from wheezing
of ripe fruit can also be taken with the cough and respiratory spasm. The leaf Acknowledgements
spoon without addition of milk and sugar. juice is mixed in warm water with a little Authors are thankful to Sh. Desh
About 60g of the fruit/edible part is pepper and is given as a drink40, 70. Kamal Bishnoi, Director, Lord Shiva
sufficient for an adult66. College of Pharmacy, Sirsa, Haryana for
Miscellaneous properties providing necessary facilities and Prof (Dr.)
In Burn cases Bael leaves are useful in jaundice D.N. Mishra, Chairman, Dept. of Pharm.
The traditional healers of and in the treatment of wounds. The Sciences, Guru Jambheshwar University,
southern Chhatisgarh use dry powder of extract of leaves is beneficial in the Hisar, Haryana for his valuable guidance.
Vol 6(2) March-April 2007 175
Review Article

References 11. Dhiman AK, In: Discussion of Plants, Sacred 22. Knight RJ Jr, Origin and world importance of
1. Yadav JP, Kumar S and Siwach P, Folk Plants and their Medicinal Uses, Daya tropical and subtropical fruit crops, In:
medicines used in gynecological and other Publication House, New Delhi, 2003, pp. 18-19. Tropical and subtropical fruits, by S Nagar
related problems by rural population of and PE Shah (Eds), AV, Westport, 1980,
12. Purohit SS and Vyas SP, In: Aegle marmelos pp. 1-120.
Haryana, Indian J Trad Knowledge, Correa ex Roxb. (Bael), Medicinal Plant
2006, 5(3), 323-326. Cultivation- A Scientific Approach, Agrobios, 23. Morton JF, Bael Fruit, In: Fruits of Warm
2. Gupta M, Biswas TK, Saha S and Debnath PK, Jodhpur, 2004, pp. 280-285. Climates, by CF Dowling (Ed), Media
Therapeutic utilization of secretory products Incorporated, 1987, pp. 187-190.
13. Bose TK, In: Fruits of India, Tropical and
of some Indian medicinal Plants: A review, Subtropical, B Mittra, Naya Prakashan, 24. Dey KL and Bahadur R, Aegle marmelos,
Indian J Trad Knowledge, 2006, 5(4), Calcutta, 1985, pp. 498-504. In: The Indigenous Drugs of India, 2nd Edn,
569-575. Pama Primlane, 1973, pp. 12-13.
14. Sharma VK, In: Wasteland Horticulture, A.P.H.
3. Setia G, Luthra P and Sharma PC, Siddha Publishing Corporation, New Dehli, 1997, 25. Atal CK and Kapur BM, Medicinal and Aromatic
System: An ancient heritage of India, In: pp. 40, 89. Plants in North-West India, In: Cultivation
Proceedings of National Seminar on Role of and Utilization of Medicinal and Aromatic
Medicinal and Aromatic Plants in Ayurvedic, 15. Agarwal VS, Rural Economics of Medicinal Plants, Regional Research Laboratory, Jammu
Unani and Siddha systems of medicine, Hisar, Plants: Vegetation in the Forests, In: Drug Tawi, Reprint Edn, 1997, pp. 441-457.
2005, pp. 11-14. Plants of India, Vol. 1, Kalyani Publishers,
New Delhi, 1997, pp. 1, 6, 44, 45, 102, 103, 26. Jauhari OS and Singh RD, Bael — a valuable
4. Jain JB, Kumane SC and Bhattacharya S, 129, 160. fruit, Indian Hortic, 1971, 16, 9-10.
Medicinal flora of Madhya Pradesh and
Chhattisgarh — A review, Indian J Trad 16. Sambamurthy AVSS and Subrahmanyam NS, 27. Farooq S, In: 555 Medicinal Plants: Field and
Knowledge, 2006, 5(2), 237-242. Fruits and Nuts, A Text Book of Economic Laboratory Mannual, International Book
Botany, Wiley Eastern Limited, New Delhi, Distributors, Dehra Dun, 2005, pp. 40-42.
5. Chakraborty MK and Bhattacharjee A, Some 1989, Vol. 4, pp. 697-698.
common ethnomedicinal uses for various 28. Kokate CK, Purohit AP and Gokhale SB, Drugs
diseases in Purulia district, West Bengal, 17. Jauhari OS, Singh RD and Awati RK, Survey of containing glycosides, In: Pharmacognosy,
Indian J Trad Knowledge, 2006, 5(4), some important varieties of Bael (Aegle 21st Edn, Nirali Prakashan, Pune, 2002,
554-558. marmelos Correa), Punjab Hortic J, pp.158-239.
1969, 9, 48-53.
6. Gupta V, Role of exotic medicinal and 29. Tuticorin RG and Manakkal SP, Some
aromatic plants in Indian systems of 18. Parmar C and Kaushal MK, Aegle marmelos alkaloids from Aegle marmelos,
medicines, In: Proceedings of National Correa, In: Wild Fruits of the Sub-Himalayan Phytochemistry, 1983, 22(3), 755-757.
Seminar on Role of Medicinal and Aromatic Region, Kalyani Publishers, New Delhi, 1982,
Plants in Ayurvedic, Unani and Siddha systems pp. 1-5. 30. Sharma BR, Rattan RK and Sharma P,
of medicine, Hisar, 2005, pp. 63-65. Marmeline, An alkaloid and other
19. Kala CP, Ethnobotany and ethnoconservation components of unripe fruits of Aegle
7. Tandon V and Thayil S, Saving medicinal plants of Aegle marmelos (L.) Correa, Indian J marmelos, Phytochemistry, 1981,
in South India, Plants Talk 2, 1995, 16-17. Trad Knowledge, 2006, 5(4), 537-540. 20(11), 2606-2607.
8. Singh S, Standardization of Processing 31. Manandhar MD, Shoeb A, Kapil RS and Popli
20. Lampronti I, Martello D, Bianchi N, Borgatti
Technology of Bael (Aegle marmelos SP, New alkaloids from Aegle marmelos,
M, Lambertini E, Piva R, Jabbar S, Choudhari
Correa). Thesis, Doctor of Philosophy in
MS, Khan MT and Gambari R, In vitro Phytochemistry, 1978, 17, 1814-1815.
Horticulture, College of Agriculture CCS, HAU,
antiproliferate effects on human tumour cell 32. Evans WC, Saponin, Cardioactive Drugs and
Hisar, 2000, pp. 1-3.
lines of extract from the Bangledeshi other Stories, In: Trease and Evans
9. Ansary PY, In: A hand book on the plant medicinal plant Aegle marmelos Correa, Pharmacognosy, 15th Edn, British Library
sources of indigenous drugs, International Phytomedicine, 2003, 10(4), 300-308. Cataloguing in Publication Data, 2002,
Book Distributors, Dehra Dun, 2005, pp. 36. pp. 294-298.
21. Karunanayake EH, Welihinda J, Sirimanne SR
10. The Useful Plants of India, Publication and and Sinnadoria H, Oral hypoglycemic activity 33. Basak RK, Mandal PK and Mukherjee AK,
Information Directorate, CSIR, New Delhi, of some medicinal plants of Sri Lanka, Investigation on the structure of a
1986, pp. 16-17. J Ethnopharmacol, 1984, 11(2), 223-231. hemicellulose fraction isolated from the trunk

176 Natural Product Radiance


Review Article
of a young Bael (Aegle marmelos) tree, 45. Gaur RD and Tiwari JK, Indigenous medicinal hyperglycemic rats, J Environ Biol, 2001,
Carbohydr Res, 1982, 104(2), 309-317. plants of Garhwal Himalaya (India): An 22(1), 53-57.
Ethonobotanical Study, In: Medicinal and
34. Rangari VD, In: Traditional Drugs of India: poisonous plant of tropics, AJM Leeuwenberg 54. Saxena A and Vikram VK, Role of selected
Pharmacognosy and Phytochemistry Part-II, (Ed), International Book Distributors, Dehra Indian plants in management of Type II
1st Edn, Carrier Publications, Nasik, 2004, Dun, 1988, pp. 139-143. diabetes: A review, J Altern Complement
pp. 182-184. Med, 2004, 10(2), 369-378.
46. Upadhya S, Shanbhag KK, Suneetha G,
35. Ali MS and Pervez MK, Marmenol: A 7- Balchandra NM and Uphadya S, A study of 55. Akhtar J, Jamil S and Azhar MU, Diabetes
geranyloxy coumarin from the leaves of Aegle hypoglycemic and antioxidant activity of mellitus: Prevention and Management, Nat
marmelos Corr., Nat Prod Res, 2004, Aegle marmelos in alloxan induced Prod Rad, 2005, 4(5), 413-415.
18(2), 141-146. diabetic rats, Indian J Physiol
56. Lambertine E, Piva R, Khan MT, Lampronti I,
Pharmacol, 2004, 48(4), 476-480.
36. Useful plants of India and Pakistan: A popular Bianchi N, Borgatti M and Gambari R, Effects
handbook of Trees and Plants of Industrial, 47. Gholap S and Kar A, Hypoglycaemic effects of of extract from Bangladeshi medicinal plants
Economic and Commercial Utility, by JF some plant extracts are possibly mediated on in vitro proliferation of human breast
Dastur, D.B.Taraporewala Sons and Co. Ltd., through inhibition in cortico-steroid cancer cell lines and expression of estrogen
Bombay, 1968, pp.15-16. concentration, Pharmazie, 2004, 59 (11), receptor alpha gene, Int J Oncol, 2004,
876-878. 24(2), 419-423.
37. Agarwal VS, Economic Plants of India, Kailash
Parkashan, Calcutta, 1990, pp. 3-9. 48. Kar A, Choudhary BK and Bandyopadhyay NG, 57. Costa-Luatufo LV, Khan MTH, Ather A, Wilke
Comparative evaluation of hypoglycaemic DV, Jimenez PC, Pessoa C, Moaraes MEA and
38. Reuther W, Webber HJ and Batcher LD, The activity of some Indian medicinal plants in Moreas MOD, Studies of anticancer potential
Citrus Indrustry, University of California, 1967, alloxan diabetic rats, J Ethnopharmacol, of plants used in Bangladeshi folk medicine,
Vol. I, pp. 407-409. 2003, 84 (I), 105-108. J Ethnopharmacol, 2005, 99(1) 21-30.

39. Shankar G and Garg KL, In: Nutritional value 49. Sabu MC and Kuttan R, Antidiabetic acitivity 58. Jagetia GC and Baliga MSVP, Fruit extract of
of some important fruits, Handbook of of Aegle marmelos and its relationship with Aegle marmelos protects mice against
Horticulture, Kitabistan, Allahabad, 1967, its antioxidant properties, Indian J Physiol radiation-induced lethality, Integr Cancer
pp. 37-41. Pharmacol, 2004, 48(1), 81-88. Ther, 2004, 3(4), 323-332.

40. Paricha S, Bael (Aegle marmelos) Nature’s 50. Seema PV, Sudha B, Pius SP, Asha A, Reghu 59. Prince PS and Rajadurai M, Preventive effect
most natural Medicinal Fruit, Orissa Rev, KG and Paulose CS, Kinetic studies of purified of Aegle marmelos leaf extract on
2004, 16-17. malate dehydrogenase in liver of isoprenaline-induced myocardial infraction
streptozotocin-diabetic rats and the effect of in rats, J Pharm Pharmacol, 2005,
41. Chopra’s Indigenous Drugs of India, by RN leaf extract of Aegle marmelos (L.) Correa 57(10), 1353-1357.
Chopra, LC Chopra, KL Handa and LD Kapur, ex Roxb., Indian J Exp Biol, 1996, 34,
U N Dhar and Sons Private Ltd., Calcutta, 1985, 600-602. 60. Sur TK, Pandit S and Pramanik T,
Vol. II, pp. 267-269. Antispermatogenic activity of leaves of Aegle
51. Nurendhirakann RT, Subramanian S and marmelos Corr. in albino rats, A preliminary
42. Lamba BV and Bhargava KP, Activity of some Kandaswamy M, Mineral content of some report, Biomedicine, 1999, 19, 199-202.
synthetic and natural products against medicinal plants used in treatment of diabetes
experimental Ankylostomiasis, Indian J mellitus, Biol Trace Elem Res, 2005, 61. Rana BK, Singh UP and Taneja V, Antifungal
Pharmacol, 1969, 1. 103(2), 109-115. activity and kinetic of inhibition by essential
oil isolated from leaves of Aegle marmelos,
43. Shoba FD and Thomos M, Study of 52. Kamalakkannan N and Prince PSM, Effect of J Ethnopharmacol, 1997, 57(1), 29-34.
antidiarrhoeal activity of four medicinal plants Aegle marmelos Correa (Bael) fruit
in castor-oil induced diarrhoea, extracts on diabetic rats, Indian J Exp Biol, 62. Jagetia GC, Venkatesh P and Baliga MS,
J Ethnopharmacol, 2001, 76(1), 73-76. 2003, 41, 1285-1288. Evaluation of the radioprotective effect of Bael
leaf (Aegle marmelos) extract in mice, Int
44. Roy SK and Singh RN, Studies on changes 53. Sachdewa A, Raina D, Srivastava AK and J Radiat Biol, 2004, 80(4), 281-290.
during development and ripening of Bael Khemanio LD, Effect of the Aegle marmelos
fruit, Punjab Hortic J, 1980, 20(3&4), and Hibiscus rosa sinensis leaf extract 63. Jagetia GC, Venkatesh P and Baliga MS, Aegle
190-197. on glucose tolerance in glucose induced marmelos (L.) Correa inhibits the

Vol 6(2) March-April 2007 177


Review Article
proliferation of transplanted Ehrlich ascites pyrano-coumarin and isocoumarin and their 73. Kar A, Panda S and Bharti S, Relative efficacy
carcinoma in mice, Biol Pharm Bull, 2005, effect on prostanoid synthesis using human of three medicinal plant extracts in the
28(1), 58-64. colonic mucosa, Indian J Exp Biol, 2000, alteration of thyroid hormone concentration
35(10), 1080-1083. in male mice, J Ethnopharmacol, 2002,
64. Arul V, Miyazaiki S and Dahananjaya R, Studies 81(2), 281-285.
on the anti-inflammatory, antipyretic, 69. Banerji M, Maiti M, Sem S and Datta PC,
analgesic properties of the leaves of Aegle Pharmacognosy of Aegle marmelos (L.) 74. Basu DK and Brahmankar DM, Studies on
marmelos, J Ethnopharmacol, 2005, Correa seed. A new protein source, Acta interactions of calcium antagonist with
96(1-2), 159-163. Pharm Hung, 1982, 52(3), 97-101. cardioacitve agents, Indian J Pharmacol,
1983, 15(4), 321-330.
65. Tiwari NN and Joshi MP, Medicinal plants of 70. Reddy KN, Reddy CS and Trimurthulu S,
Nepal II, J Nep Med Assoc, 1990, 28, Ethnobotanical survey on respiratory disorders 75. Ahuja BS, Aegle marmelos, In: Medicinal
221-232, 266-279. in Eastern Ghats of Andhra Pradesh, India, plants of Saharanpur, 1 st Edn Dhrampal
www.sis.edu/~ebl/leaflets/reddy.htm, dated Vidhyalankar Publisher, Gurukul Kangri
66. Roy SK and Singh RN, Studies on changes Vishawvidyalaya, Hardwar, 1965, pp. 10-11.
05/12/2006.
during development and ripening of Bael
fruit, Punjab Hortic J, 1980, 20(3&4), 71. Devadi G, Importance of Bael and its 76. Haider R, Khan AK, Aziz KM, Chowdhury A
190-197. use in health care, In: Kalyan Aarogaya Ank, and Kabir I, Evaluation of indigenous plants
Geeta Press Gorakhpur, 2002, Vol. 2, in treatment of acute shizellosis, Trop Geogr
67. Pankaj Oudhia, Bael (Aegle marmelos syn. Med, 1991, 43(3), 266-270.
pp. 401-402.
Crataeva marmelos) as medicinal herb
in Chhattisgarh, Research Notes, Article 107, 72. Kala CP, Farooquee NA and Majila BS, 77. Yadav SK, Jain AK, Tripathi SN and Gupta JP,
www. botanical.com, dated 26.9.2005. Indigenous knowledge and medicinal plants Irritable bowel syndrome: Therapeutic
used by Vaidyas in Uttaranchal, India, Nat evaluation of indigenous drugs, Indian J
68. Goel RK, Maiti RN, Manickan M and Ray AB, Med Res, 1989, 90, 496-503.
Prod Rad, 2005, 4(3), 195-204.
Antiulcer acitivity of naturally occurring

178 Natural Product Radiance

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